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Cortexin - instructions for use, analogs, reviews and release forms (injections in injectable ampoules (lyophilizate) 5 mg and 10 mg) of the drug for the treatment of encephalopathy in adults, children (including newborns) and pregnancy "Page 3

Cortexin - instructions for use, analogs, reviews and release forms (injections in injections (lyophilizate) 5 mg and 10 mg) drug for the treatment of encephalopathy in adults, children (including newborns) and pregnancy

In this article, you can read the instructions for using the drug Cortexin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Cortexin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Cortexin in the presence of existing structural analogues.Use for the treatment of encephalopathies and cerebral circulation disorders in adults, children (including newborns), as well as during pregnancy and lactation.

 

Cortexin - Nootropic preparation.

 

Contains a complex of low molecular weight water-soluble polypeptide fractions with a molecular weight of no more than 10 000 Da, isolated from the cerebral cortex of cattle or pigs not older than 12 months of age. It penetrates through the BBB directly to the nerve cells. The drug has nootropic, neuroprotective, antioxidant and tissue-specific effects.

 

Nootropic action

 

Improves the higher functions of the brain, learning and memory processes, concentration of attention, stability under various stresses.

 

Neuroprotective action

 

Protects neurons from damage by various endogenous neurotoxic factors (glutamate, calcium ions, free radicals), reduces the toxic effects of psychotropic substances.

 

Antioxidant action

 

It inhibits lipid peroxidation in neurons, increases the survival of neurons in conditions of oxidative stress and hypoxia.

 

Tissue-specific effect

 

It activates the metabolism of neurons of the central and peripheral nervous system, reparative processes, contributes to the improvement of the functions of the cerebral cortex and the general tone of the nervous system.

 

Pharmacokinetics

 

The complex composition of Cortexin, the active substance of which is a complex of polypeptide fractions, does not allow the usual pharmacokinetic analysis of individual components.

 

Indications

 

In the complex therapy of the following conditions and diseases:

  • disorders of cerebral circulation;
  • craniocerebral trauma and its consequences;
  • encephalopathy of various genesis;
  • Cognitive impairment (including memory disorders and thinking);
  • acute and chronic encephalitis and encephalomyelitis;
  • epilepsy;
  • asthenic conditions;
  • supra-segmental vegetative disorders (vegetative-vascular dystonia);
  • decreased ability to learn;
  • delay of psychomotor and speech development in children;
  • critical conditions of newborns with perinatal damages of the nervous system;
  • various forms of infantile cerebral palsy.

 

Forms of release

 

Lyophilizate for solution for intramuscular injection (injections in ampoules for injection) 5 mg and 10 mg.

 

There are no other forms of release, including tablets or capsules.Perhaps this is a fake.

 

Instructions for use and dosage

 

The drug is administered intramuscularly.

 

Children with a body weight of less than 20 kg of the drug administered at a dose of 0.5 mg / kg of body weight, with children weighing more than 20 kg - at a dose of 10 mg per day for 10 days.

 

If necessary, repeat the course in 3-6 months.

 

Rules for the preparation of solution

 

The contents of the vial are dissolved in 1-2 ml of 0.5% solution of procaine (novocaine), water for injection or 0.9% sodium chloride solution.

 

Side effect

  • individual hypersensitivity to the components of the drug.

 

Contraindications

  • pregnancy;
  • lactation period (breastfeeding);
  • individual intolerance of the drug.

 

Application in pregnancy and lactation

 

The drug is contraindicated for use in pregnancy due to lack of data from clinical studies.

 

If it is necessary to prescribe the drug during lactation, breastfeeding should be stopped (due to the lack of data from clinical trials).

 

Drug Interactions

 

Drug interaction of the drug Cortexin is not described.

 

Analogues of the drug Cortexin

 

Structural analogues of the active substance of the drug Cortexin has not.However, there is a large class of drugs of nootropics with a similar mechanism of action. Preparations of this type are:

  • Aminalon;
  • Ampasse;
  • Bilobil;
  • Gamma-aminobutyric acid;
  • Glycine;
  • Glutamic acid;
  • Hopantenic acid;
  • Idebenon;
  • Lucetsam;
  • Nootropil;
  • Pantogam;
  • Piracetam;
  • Semax;
  • Tenoten;
  • Tenoten for children;
  • Fenibut;
  • Phenotropil;
  • Holilitil;
  • Cebrilysin;
  • Ceraxon;
  • Cerebramine;
  • Cerebrial;
  • Cerebrosolate;
  • Cerebrolysin;
  • Encephabol;
  • The escotrope.

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Reviews (236):
Visitors
sveta_kolo74
Good afternoon. Have discharged cortexin, neuroks and glycine for 10 injections. Cortexin and glycine alternate with the neurox every other day. But after 10 days the neuroxis will end. How to continue?
Administrators
admin
sveta_kolo74, Alternation implies that on the day when colitis is one drug, do not introduce another, especially for injecting drugs.In your case, as I understand it, Cortexin and Glycine take in one day, the next day you do an injection of Neurox and alternate before the end of the course of therapy. Therefore, all drugs must end at the same time. Any ambiguities in the dosing regimen should be clarified by the doctor who prescribes treatment for you.
Visitors
Yuliya0676
Hello! My daughter is 3.5 years old. Have diagnosed paralytic strabismus. The doctor, in combination with other drugs, prescribed cortexin. Is it effective in such diseases?
Administrators
admin
Yuliya0676, Disease rare and sane statistics of the use of any medication you will not find. As far as I know, such diseases do not succumb to any conservative therapy.
Guests
Olesya
Hello. We are 2 years and 3 months old. The weight of the child is 13 kg. Have appointed or nominated a cortexin of 10 mg. Dosage of 8 mg. If you dilute the drug with 2 ml novocaine, then take a solution you need 1.6 ml? I understand correctly? Is the dose for our weight exceeded? If we count according to the instructions, then we need 1.3 ml?
Guests
Angelinka
I want to tell our story. My son is diagnosed with PPR. I scold myself for giving in to the recommendations of well-wishers. The matter is that from early childhood my child grew silent. At first I was advised to wait until three years. I, naive, waited. Then they said: wait until you go to the kindergarten, there to talk. I again waited, I believed experienced moms and grandmothers. She waited. Now, because of my omission, my child is studying in a correctional school, with difficulty adapting to the external environment and talking very badly.
Itself is to blame, and I bear this cross. The only thing that helps my son, even for a while, is Cortexin's injections: he becomes more active, begins to learn the school material better. For me, as for my mother, this is a huge breakthrough and joy.
Advice to all mom: do not listen to any of your girlfriends. If you notice abnormalities in your child, contact a specialist immediately. Modern diagnostic methods will allow early detection of the disease and prevent the result of oversight, which turned out in my case, and supportive drugs, like Cortexin, will help fight the disease more effectively.
Administrators
admin
OlesyaAccording to your child's instructions, a dose of 6.5 mg Cortexin is given. If you dissolve the ampoule of the drug at a dosage of 10 mg of 2 ml of Novocaine, you will need to inject 1.3 ml of the prepared solution for injection. If you fulfill the individual prescription of a doctor who prescribed a dosage of 8 mg per reception, then yes it will be necessary to collect 1.6 ml of the finished solution.
Visitors
maiya2010
Good afternoon. We were discharged neuromultivitis and pantogam. Please tell me which is better. And why were not we discharged cortexin? Can the doctor ask for a discharge of cortexin?
Administrators
admin
maiya2010, And how do I know that you are better. Neither the medical history, nor the diagnosis, nor the description of the patient is present, and psychics do not have a lot to learn about it. The complex for the treatment of neurologic pathology has been prescribed, probably the doctor found this set of medicines more suitable for your situation. Medications are not bad.
Visitors
Jeka
Hello.My doctor prescribed medications for 15 mg of meloxicam for 1 ton # 1p / day (10 days), Vinpocetine 1 ton # 3 r / day (1 month), Cortexin 10 mg IM / 1 # once a day (10 days) (raise 4 ml novocaine), magnelis6, beta-histidine in vegetative-vascular dystonia. Has started to take medicines (except for nyxes) the pressure began to fall, and tell or say please it is possible to accept all these medicines and nyxes together?
Administrators
admin
Jeka, According to the instructions, some of the drugs indicated in the question are able to raise blood pressure as reported side effects, rather than lower it. Meloksikam, Vinpocetin, have this property. You can try to cancel Vinpocetine for a while, because by experience this drug can cause instability with pressure values. Perhaps an idiosyncrasy developed into a group of drugs, or there is an allergic reaction accompanied by a lowering of blood pressure, which requires urgent medical intervention and correction of therapy. Given the number of medications taken, it is better to consult a doctor who has prescribed this treatment regimen for a competent assessment of the situation, taking into account the existing concomitant diseases and conditions.
Guests
Irina
Hello. Her husband's Parkinson's disease is a rigid, trembling form. When the cola cortexin, it becomes noticeably better and speech becomes legible.
Visitors
Juliashem
Hello. To the child 5 months. They put hypertension, arms in tension, often crying, do not turn over, although it crawls in a plastic way. At the reception of a neurologist for nsg the doctor diagnosed gliosis, asymmetry. Assign cortexin at 10 mg every other day, 10 times, and pantogam at 0.4 - 2 r per day for a month. Question on cortexin: according to the instructions, the dose is large, but the doctor explained that they do not immediately excrete from the body, but he works also the next day, therefore every other day. How legitimate is this dosage and not daily? Also have noticed that as have started to put korteksin (and it was more on day of a nyxis), became more strained, tearful and there were also intrusive movements by the right arm or hand. Whether it depends on the drug and whether it is temporary, maybe the drug does not go to us, or is it such an action, should we continue to put it? And an additional question, can clear up: the doctor explained, saying the vessel in the brain is tense, it is necessary to relax it, and it says "gliosis".How dangerous is this diagnosis, because the internet writes little good about it.
Administrators
admin
Juliashem, The instructions are written unambiguously - for children with a body weight of up to 20 kg Cortexin is prescribed in a dose of 0.5 mg / kg. Since the weight of the child is not specified, you can count the numbers on the weight of your baby yourself. And your appointment is an experiment of your doctor, flavored with the experience of his small sample of your own patients and you can not trust such a thing to the full.

All other issues should be solved with an intelligent pediatric neurologist in person, because the symptoms, doctor's explanations and diagnoses in your case do not coincide. Gliosis and then the vessel is "tense", that the reason is that the consequence is whether the porridge is in the doctor's head, or whether you explain it.

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