Spazmol - instructions for use, reviews, analogs and forms of release (tablets 40 mg, injections in ampoules for injection 2 ml) of the drug for the treatment of abdominal pain, with menstruation, colic in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drugSpazmol. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists in the use of Spasmol in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Spazmola in the presence of existing structural analogues. Use for the treatment of abdominal pain, with menstruation, gastric, kidney,hepatic colic and spasms in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Spazmol - antispasmodic myotropic action. The chemical structure and pharmacological properties are close to papaverine, but it has a stronger and longer action. Reduces the tone and motor activity of the smooth muscles of the internal organs, dilates the blood vessels.

Composition

Drotaverina hydrochloride + excipients.

Pharmacokinetics

After taking the drug inside the absorption is high, the half-absorption period is 12 minutes. Bioavailability is 100%. Time to reach the maximum concentration in blood plasma - 2 hours.

Evenly distributed in tissues, penetrates into cells of smooth muscles. Binding to plasma proteins is 95-98%. Does not penetrate the blood-brain barrier (BBB). It is mainly excreted by the kidneys, to a lesser extent - with bile.

Indications

• prevention and treatment of functional conditions and pain syndrome caused by spasm of smooth muscles (including chronic gastroduodenitis, spastic colitis, chronic cholecystitis, cholelithiasis,peptic ulcer of the stomach and duodenum; spasms of the pyloric and cardiac parts of the stomach; with urolithiasis);
• Algodismenorea (painful periods);
• to reduce uterine contractions and to relieve cervical spasm during childbirth;
• spasms of peripheral vessels;
• spasms of cerebral vessels;
• prevention of spasm of smooth muscles in the conduct of instrumental research methods.

Forms of release

Tablets of 40 mg.

Injections in ampoules for injection 2 ml.

Instructions for use and dosing regimen

Pills

Adults appoint 40-80 mg (1-2 tablets) 2-3 times a day. Children under the age of 6 years, the drug is administered orally in a single dose of 10-20 mg (one fourth or half a tablet), at the age of 6 to 12 years - 20 mg (poltabletki) 1-2 times a day.

Ampoules

Inside, intramuscularly, intravenously or subcutaneously, adults - 40-80 mg 1-3 times a day. For hepatic and renal colic, it is recommended to administer intravenously slowly in a dose of 40-80 mg.

With spasms of peripheral arteries, drotaverine can be administered intraarterially.

For children under the age of 6 years when taken orally, a single dose is 10-20 mg, 6-12 years - 20 mg, the frequency of application 1-2 times a day.

Side effect

• dizziness;
• increased sweating;
• palpitation;
• occurrence of arrhythmias
• arterial hypotension (pressure reduction);
• feeling of heat;
• allergic dermatitis;
• when administered intravenously, cases of oppression of the respiratory center are noted.

Contraindications

• severe renal failure;
• severe hepatic impairment;
• severe heart failure (low cardiac output syndrome);
• AV-blockade of 2 and 3 degrees;
• pregnancy, lactation (breastfeeding);
• children's age (for parenteral use);
• hypersensitivity to drotaverine.

Application in pregnancy and lactation

Contraindicated use of spasmol during pregnancy. For the duration of treatment, breastfeeding should be discontinued.

Use in children

With caution, use Spasmol in children. Parenteral use in children is contraindicated.

special instructions

With caution should prescribe the drug to patients with severe atherosclerosis of the coronary arteries, prostatic hyperplasia, glaucoma, arterial hypotension.

Drotaverin can be used as part of a combination therapy for the management of hypertensive crisis.

Drug Interactions

With simultaneous use with tricyclic antidepressants, quinidine, procainamide, the decrease in blood pressure, caused by tricyclic antidepressants, quinidine and procainamide, intensifies.

With simultaneous use, the spasmogenic activity of morphine decreases.

With simultaneous application with levodopa, a decrease in the antiparkinsonian effect of levodopa is possible.

With simultaneous use, the effect of papaverine, bendazole and other antispasmodics (including m-holinoblokatorov) is intensified.

With simultaneous use with phenobarbital, the spasmolytic effect of Drotaverin increases.

Analogues of the drug Spazmol

Structural analogs for the active substance:

• Trust;
• Droverin;
• Drotaverine;
• The nose-sconce;
• But the spine;
• But Forte's spade;
• Ple-Spa;
• Spasmonet;
• Cosporeine;
• Spacock.

Analogues on the pharmacological group (myotropic antispasmodics):

• Avisan;
• Altalex;
• Bendazole;
• Galidor;
• Dibazol;
• Dicetel;
• Driptan;
• Duspatalin;
• Dutan;
• Kellin;
• Librax;
• Mebeverin;
• Neobutin;
• Niaspam;
• Novitropane;
• Oxybutine;
• Papaverine;
• Plantex;
• Platyphylline;
• Spasmodic;
• Sparex;
• Talinda;
• Trimedate;
• Cystenal;
• Cystrin;
• Enablex.

Response of a therapist

Spasmol is a good drug for alleviating the condition of patients with renal, hepatic, gastric colic and spasmodic pain. I recommend medicine for patients with ulcerative gastrointestinal lesions, with exacerbation of urolithiasis and cholelithiasis. Spasmol is perfect for women suffering from painful menstruation. In addition, the active substance of the drug drotaverin is able to dilate the blood vessels, so Spasmol is often prescribed as part of the combined treatment of hypertensive crisis. The drug has no contraindications and side effects are not many - the treatment is tolerated by the patients well.

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