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Prednisolone - instructions for use, reviews, analogs and formulations (1 mg and 5 mg tablets, injections for injections, eye drops, 0.5% ointment) for the treatment of shock conditions in adults, children and pregnancy

Prednisolone - instructions for use, reviews, analogs and formulations (1 mg and 5 mg tablets, injections for injections, eye drops, 0.5% ointment) for the treatment of shock conditions in adults, children and pregnancy

In this article, you can read the instructions for the use of a medicinal hormone drug Prednisolone. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Prednisolone in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of prednisolone in the presence of existing structural analogues.Use for the treatment of shock and urgent conditions, allergic reactions, inflammatory manifestations in adults, children, as well as during pregnancy and lactation.

 

Prednisolone - a synthetic glucocorticoid drug, a dehydrated analog of hydrocortisone. Has anti-inflammatory, antiallergic, immunosuppressive action, increases the sensitivity of beta-adrenoreceptors to endogenous catecholamines.

 

Interacts with specific cytoplasmic receptors (receptors for GCS are present in all tissues, especially in the liver), with the formation of a complex inducing the formation of proteins (including enzymes that regulate vital processes in cells.)

 

Protein metabolism: reduces the number of globulins in the plasma, increases the synthesis of albumins in the liver and kidneys (with increasing albumin / globulin ratio), reduces synthesis and enhances protein catabolism in muscle tissue.

 

Lipid metabolism: increases synthesis of higher fatty acids and triglycerides, redistributes fat (accumulation of fat occurs mainly in the area of ​​the shoulder girdle, face, abdomen), leads to the development of hypercholesterolemia.

 

Carbohydrate metabolism: increases the absorption of carbohydrates from the digestive tract; increases the activity of glucose-6-phosphatase (increased intake of glucose from the liver into the blood); increases the activity of phosphoenolpyruvate carboxylase and the synthesis of aminotransferases (activation of gluconeogenesis); promotes the development of hyperglycemia.

 

Water-electrolyte metabolism: retards sodium and water in the body, stimulates the excretion of potassium (mineralocorticoid activity), reduces absorption of calcium from the digestive tract, reduces the mineralization of bone tissue.

 

The anti-inflammatory effect is associated with the suppression of the release of eosinophils and mast cells by inflammatory mediators; inducing the formation of lipocortins and reducing the number of mast cells that produce hyaluronic acid; with a decrease in the permeability of capillaries; stabilization of cell membranes (especially lysosomal) and membranes of organelles. Effects on all stages of the inflammatory process: inhibits the synthesis of prostaglandins at the level of arachidonic acid (lipocortin depresses phospholipase A2, suppresses the liberation of arachidonic acid and inhibits the biosynthesis of endopersides, leukotrienes,inflammatory cytokines "(interleukin 1, tumor necrosis factor alpha, etc.); increases the resistance of the cell membrane to the action of various damaging factors.

 

Immunosuppressive effect is caused by induced lymphoid tissue involution, suppression of lymphocyte proliferation (especially T-lymphocytes), suppression of B-cell migration and interaction of T and B lymphocytes, inhibition of release of cytokines (interleukin-1, 2, gamma-interferon) from lymphocytes and macrophages and a decrease in the formation of antibodies.

 

The antiallergic effect develops as a result of a decrease in the synthesis and secretion of mediators of allergy, inhibition of release from sensitized mast cells and basophils of histamine and other biologically active substances, a decrease in the number of circulating basophils, T- and B-lymphocytes, mast cells; suppression of the development of lymphoid and connective tissue, reducing the sensitivity of effector cells to mediators of allergy, inhibition of antibody formation, changes in the immune response of the body.

 

In obstructive airway diseases, the effect is mainly due to the inhibition of inflammatory processes,prevention or reduction of the degree of edema of the mucous membranes, a decrease in the eosinophilic infiltration of the submucosal layer of the bronchial epithelium and the deposition of circulating immune complexes in the bronchial mucosa, as well as inhibition of erosion and desquamation of the mucosa. Increases the sensitivity of beta-adrenergic receptors of small and medium-sized bronchial tubes to endogenous catecholamines and exogenous sympathomimetics, reduces the viscosity of mucus by reducing its production.

 

Suppresses the synthesis and secretion of ACTH and, again, the synthesis of endogenous glucocorticosteroids.

 

It inhibits connective tissue reactions during the inflammatory process and reduces the possibility of scar tissue formation.

 

Pharmacokinetics

 

Prednisolone is metabolized in the liver, partially in the kidneys and other tissues, mainly by conjugation with glucuronic and sulfuric acids. Metabolites are inactive. It is excreted with bile and urine by glomerular filtration and is reabsorbed by tubules by 80-90%.

 

Indications

  • shock conditions (burn, traumatic, operational, toxic, cardiogenic) - with ineffectiveness of vasoconstrictors, plasmal replacement drugs and other symptomatic therapy;
  • allergic reaction (acute severe), transfusion shock, anaphylactic shock, anaphylactoid reactions;
  • brain edema (including on the background of a brain tumor or associated with surgery, radiation therapy, or head injury);
  • bronchial asthma (severe form), asthmatic status;
  • systemic connective tissue disease (systemic lupus erythematosus, scleroderma, polyarteritis nodosa, dermatomyositis, rheumatoid arthritis);
  • acute and chronic inflammatory diseases of the joints - gouty and psoriatic arthritis, osteoarthritis (including post-traumatic), polyarthritis, humeropathy periarthritis, ankylosing spondylitis (Bechterew's disease), juvenile arthritis, Still's syndrome in adults, bursitis, nonspecific tenosynovitis, synovitis and epicondylitis ;
  • skin diseases - pemphigus, psoriasis, eczema, atopic dermatitis (common atopic dermatitis), contact dermatitis (affecting a large skin surfaces), drug reaction, seborrheic dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell's syndrome), bullous herpetiformis dermatitis, Stevens-Johnson syndrome ;
  • allergic eye diseases: allergic forms of conjunctivitis;
  • inflammatory diseases of the eyes - sympathetic ophthalmia, severe sluggish anterior and posterior uveitis, optic neuritis;
  • congenital adrenal hyperplasia;
  • blood diseases and hematopoiesis system - agranulocytosis, panmyelopathy, autoimmune hemolytic anemia, acute lympho- and myeloid leukemia, lymphogranulomatosis, thrombocytopenic purpura, secondary thrombocytopenia in adults, erythroblastopenia (erythrocyte anemia), congenital (erythroid) hypoplastic anemia;
  • berylliosis, Leffler's syndrome (not susceptible to other therapy); lung cancer (in combination with cytostatics);
  • multiple sclerosis;
  • prevention of graft rejection during organ transplantation;
  • hypercalcemia on the background of cancer, nausea and vomiting during cytostatic therapy;
  • myeloma;
  • thyrotoxic crisis;
  • acute hepatitis, hepatic coma;
  • Reduction of inflammatory phenomena and prevention of cicatricial narrowing (with poisoning by cauterizing fluids).

 

Forms of release

 

Tablets 1 mg and 5 mg.

 

Solution for intravenous and intramuscular injection (injections in ampoules for injection) 30 mg / ml.

 

Eye drops 0.5%.

 

Ointment for external use 0,5%.

 

Instructions for use and dosage

 

Injections

 

The dose of Prednisolone and the duration of treatment are set by the doctor individually, depending on the indications and severity of the disease.

 

Prednisolone is administered intravenously (by drip or jet) in droppers or intramuscularly. In / in the preparation is usually injected first with a stream, then drip.

 

In acute adrenal insufficiency, a single dose of 100-200 mg for 3-16 days.

 

In bronchial asthma, the drug is administered depending on the severity of the disease and the effectiveness of complex treatment from 75 to 675 mg for a course of treatment of 3 to 16 days; in severe cases, the dose may be increased to 1,400 mg per treatment course and more with a gradual dose reduction.

 

With asthmatic status Prednisolone is administered at a dose of 500-1200 mg per day, followed by a decrease to 300 mg per day and transition to maintenance doses.

 

In thyrotoxic crisis, 100 mg of the drug are administered at a daily dose of 200-300 mg; if necessary, the daily dose can be increased to 1000 mg. The duration of administration depends on the therapeutic effect, usually up to 6 days.

 

In the case of shock resistant to standard therapy, prednisolone is usually injected at the start of the therapy, after which it is switched to a drop introduction.If the BP does not increase within 10-20 minutes, repeat the fluid administration of the drug. After excretion from the shock state, the drip administration continues until the BP stabilizes. Single dose is 50-150 mg (in severe cases - up to 400 mg). Repeated drug is administered after 3-4 hours. The daily dose can be 300-1200 mg (with a subsequent dose reduction).

 

In acute hepatic-renal failure (acute poisoning, postoperative and postpartum periods, etc.), prednisolone is administered at 25-75 mg per day; in the presence of indications, the daily dose can be increased to 300-1500 mg per day or more.

 

In rheumatoid arthritis and systemic lupus erythematosus Prednisolone is administered in addition to the systemic administration of the drug at a dose of 75-125 mg per day for not more than 7-10 days.

 

In acute hepatitis Prednisolone is administered at 75-100 mg per day for 7-10 days.

 

When poisoning with cauterizing liquids with burns of the digestive tract and upper respiratory tract Prednisolone is prescribed in a dose of 75-400 mg per day for 3-18 days.

 

If it is impossible to / in the introduction of prednisolone is administered in / m in the same doses. After relief of acute condition, Prednisolone is given intravenously in tablets, followed by a gradual decrease in dose.

 

With prolonged use of the drug, the daily dose should be reduced gradually. Long-term therapy can not be stopped suddenly!

 

Pills

 

The entire daily dose of the drug is recommended to take a single or double daily dose every other day, taking into account the circadian rhythm of the endogenous secretion of glucocorticosteroids in the interval from 6 to 8 am. A high daily dose can be divided into 2-4 doses, with a large dose taken in the morning. Tablets should be taken orally during or immediately after meals, with a small amount of liquid.

 

In acute conditions and as a replacement therapy, adults are prescribed in an initial dose of 20-30 mg per day, the maintenance dose is 5-10 mg per day. If necessary, the initial dose can be 15-100 mg per day, supporting - 5-15 mg per day.

 

For children, the initial dose is 1-2 mg / kg of body weight per day in 4-6 receptions, supporting - 300-600 mcg / kg per day.

 

When the therapeutic effect is obtained, the dose is gradually reduced by 5 mg, then by 2.5 mg at intervals of 3-5 days, canceling at a later time. With prolonged use of the drug, the daily dose should be reduced gradually.Long-term therapy can not be stopped suddenly! The withdrawal of the maintenance dose is slower the longer the glucocorticosteroid therapy is used.

 

In case of stressful influences (infection, allergic reaction, trauma, surgery, mental overload), the dose of prednisolone should be temporarily increased (in 1.5-3, and in severe cases - 5-10 times) in order to avoid exacerbation of the underlying disease.

 

Side effect

  • decreased glucose tolerance;
  • Steroid diabetes mellitus or manifestation of latent diabetes mellitus;
  • oppression of adrenal function;
  • Isenko-Cushing syndrome (lunar face, pituitary-type obesity, hirsutism, increased blood pressure, dysmenorrhea, amenorrhea, muscle weakness, striae);
  • delay in sexual development in children;
  • nausea, vomiting;
  • steroid ulcer of the stomach and duodenum;
  • erosive esophagitis;
  • gastrointestinal bleeding and perforation of the gastrointestinal wall;
  • increased or decreased appetite;
  • indigestion;
  • flatulence;
  • hiccough;
  • arrhythmias;
  • bradycardia (up to cardiac arrest);
  • ECG changes characteristic of hypokalemia;
  • increased blood pressure;
  • disorientation;
  • euphoria;
  • hallucinations;
  • affective insanity;
  • depression;
  • paranoia;
  • increased intracranial pressure;
  • nervousness or anxiety;
  • insomnia;
  • dizziness;
  • headache;
  • convulsions;
  • increased intraocular pressure with possible damage to the optic nerve;
  • propensity to develop secondary bacterial, fungal or, viral infections of the eyes;
  • trophic changes of the cornea;
  • increased excretion of calcium;
  • weight gain;
  • increased sweating;
  • fluid and sodium retention in the body (peripheral edema);
  • hypokalemic syndrome (hypokalemia, arrhythmia, myalgia or muscle spasm, unusual weakness and fatigue);
  • slowing growth and ossification processes in children (premature closure of epiphyseal growth zones);
  • osteoporosis (very rare - pathological bone fractures, aseptic necrosis of the head of the humerus and femur);
  • rupture of muscle tendons;
  • decrease in muscle mass (atrophy);
  • delayed healing of wounds;
  • acne;
  • stria;
  • skin rash;
  • itching;
  • anaphylactic shock;
  • development or exacerbation of infections (the emergence of this side effect is facilitated by jointly used immunosuppressants and vaccination);
  • withdrawal syndrome.

 

Contraindications

 

For short-term use according to vital indications, the only contraindication is hypersensitivity to prednisolone or the components of the drug.

 

The preparation contains lactose. Patients with rare hereditary diseases, such as lactose intolerance, Lappease lactase deficiency or glucose-galactose malabsorption, should not take the drug.

 

With caution, the drug should be administered in the following conditions and conditions:

  • gastrointestinal diseases - peptic ulcer of stomach and duodenum, esophagitis, gastritis, acute or latent peptic ulcer, newly created intestinal anastomosis, ulcerative colitis with perforation or abscessing threat, diverticulitis;
  • parasitic and infectious diseases of a viral, fungal or bacterial nature (ongoing or recent, including recent contact with a patient)
  • herpes simplex, herpes zoster (viremic phase), chicken pox, measles; amebiasis, strongyloidiasis; systemic mycosis; active and latent tuberculosis.The use in severe infectious diseases is permissible only against the background of specific therapy;
  • pre-and post-vaccination period (8 weeks before and 2 weeks after vaccination), lymphadenitis after BCG vaccination. Immunodeficiency conditions (including AIDS or HIV infection);
  • diseases of the cardiovascular system, incl. the recently transferred myocardial infarction (in patients with acute and subacute myocardial infarction it is possible to spread the focus of necrosis, slow the formation of scar tissue and, as a result, break the heart muscle), decompensated chronic heart failure, hypertension, hyperlipidemia;
  • endocrine diseases - diabetes mellitus (including a violation of carbohydrate tolerance), thyrotoxicosis, hypothyroidism, Itenko-Cushing's disease, obesity (3-4 items);
  • severe chronic renal and / or hepatic insufficiency, nephrourolythiasis;
  • hypoalbuminemia and conditions predisposing to its occurrence (cirrhosis of the liver, nephrotic syndrome);
  • systemic osteoporosis, myasthenia gravis, acute psychosis, poliomyelitis (except for the form of bulbar encephalitis), open and closed angle glaucoma;
  • pregnancy;
  • in children during growth, glucocorticosteroids should be used only in absolute indications and under the close supervision of the treating physician.

 

Application in pregnancy and lactation

 

At pregnancy (especially in 1 trimester) apply only on vital indications.

 

Since glucocorticosteroids pass into breast milk, if it is necessary to use the drug during breastfeeding, it is recommended to stop breastfeeding.

 

special instructions

 

Before the beginning of treatment (if it is impossible due to the urgency of the condition - during the treatment), the patient should be examined for possible contraindications. Clinical examination should include the examination of the cardiovascular system, radiographic examination of the lungs, examination of the stomach and duodenum, urinary system, vision; the control of the formula of blood, the content of glucose and electrolytes in the blood plasma. During treatment with prednisolone (especially prolonged), it is necessary to observe the oculist, control the blood pressure, the state of the water-electrolyte balance, as well as the patterns of peripheral blood and blood glucose levels.

 

In order to reduce side effects, it is possible to prescribe antacids, and also to increase the intake of potassium in the body (diet, potassium preparations). Food should be rich in proteins, vitamins, with a restriction of fat, carbohydrates and table salt.

 

The effect of the drug is enhanced in patients with hypothyroidism and liver cirrhosis.

 

The drug may enhance existing emotional instability or psychotic disorders. When referring to a psychosis in an anamnesis, prednisolone in high doses is prescribed under the strict supervision of a physician.

 

In stressful situations during maintenance treatment (for example, surgical operations, trauma or infectious diseases), a correction of the dose of the drug should be made in connection with an increase in the need for glucocorticosteroids.

 

Patients should be carefully observed during the year after the end of long-term therapy with prednisolone in connection with the possible development of a relative insufficiency of the adrenal cortex in stressful situations.

 

With sudden cancellation, especially in the case of previous use of high doses, it is possible to develop withdrawal syndrome (anorexia, nausea, blocking, gyneralized musculoskeletal pain, general weakness), as well as an exacerbation of the disease for which prednisolone was prescribed.

 

During treatment with prednisolone, vaccination should not be given due to a decrease in its effectiveness (immune response).

 

When prescribing prednisolone in intercurrent infections, septic states and tuberculosis, it is necessary to simultaneously perform antibiotic treatment with bactericidal action.

 

Children during prolonged treatment with prednisolone should carefully monitor the dynamics of growth. Children who were in contact with sick measles or chickenpox during the treatment period prophylactically prescribe specific immunoglobulins.

 

Due to the weak mineralocorticoid effect for substitution therapy for adrenal insufficiency, prednisolone is used in combination with mineralocorticoids.

 

Patients with diabetes should monitor blood glucose and, if necessary, correct therapy.

 

An x-ray control of the osteoarticular system (images of the spine, hands) is shown.

 

Prednisolone in patients with latent infectious diseases of the kidneys and urinary tract can cause leukocyturia, which can have diagnostic value.

 

In Addison's disease, simultaneous administration of barbiturates should be avoided - the risk of acute adrenal insufficiency (addisonic crisis).

 

Drug Interactions

 

Simultaneous appointment of prednisolone with inducers of hepatic microsomal enzymes (phenobarbital, rifampicin, phenytoin, theophylline, ephedrine) leads to a decrease in its concentration.

 

Simultaneous prescription of prednisolone with diuretics (especially thiazide and inhibitors of carbonic anhydrase) and amphotericin B can lead to increased excretion of potassium from the body.

 

Simultaneous prescription of prednisolone with sodium-containing drugs leads to the development of edema and increased blood pressure.

 

The simultaneous administration of prednisolone with amphotericin B increases the risk of developing heart failure.

 

Simultaneous prescription of prednisolone with cardiac glycosides worsens their tolerability and increases the likelihood of developing ventricular extrasystole (due to induced hypokalemia).

 

Simultaneous prescription of prednisolone with indirect anticoagulants - prednisolone enhances the anticoagulant effect of coumarin derivatives.

 

Simultaneous prescription of prednisolone with anticoagulants and thrombolytics increases the risk of bleeding from ulcers in the gastrointestinal tract.

 

Simultaneous prescription of prednisolone with ethanol (alcohol) and non-steroidal anti-inflammatory drugs increases the risk of erosive and ulcerative lesions in the gastrointestinal tract and the development of bleeding (in combination with NSAIDs in the treatment of arthritis, a decrease in the dose of glucocorticosteroids due to the summation of the therapeutic effect) is possible.

 

Simultaneous prescription of prednisolone with Paracetamol increases the risk of hepatotoxicity (induction of hepatic enzymes and the formation of a toxic metabolite of paracetamol).

 

Simultaneous prescription of prednisolone with Acetylsalicylic acid accelerates its excretion and reduces the concentration in the blood (with the withdrawal of prednisolone, the level of salicylates in the blood increases and the risk of side effects increases).

 

Simultaneous prescription of prednisolone with insulin and oral hypoglycemic drugs, hypotensive drugs reduces their effectiveness.

 

Simultaneous prescription of prednisolone with vitamin D reduces its effect on the absorption of Ca in the intestine.

 

Simultaneous prescription of prednisolone with a somatotropic hormone reduces the effectiveness of the latter, and with praziquantel - its concentration.

 

Simultaneous prescription of prednisolone with m-holinoblokatorami (including antihistamines and tricyclic antidepressants) and nitrates contributes to increased intraocular pressure.

 

Simultaneous prescription of prednisolone with Isoniazid and mexiletine increases the metabolism of isoniazid, mexiletine (especially in "fast" acetylators), which leads to a decrease in their plasma concentrations.

 

Simultaneous prescription of prednisolone with inhibitors of carbonic anhydrase and amphotericin B increases the risk of osteoporosis.

 

Simultaneous prescription of prednisolone with Indomethacin - displacing prednisolone from bond with albumin, increases the risk of its side effects.

 

Simultaneous prescription of prednisolone with ACTH increases the effect of prednisolone.

 

The simultaneous administration of prednisolone with ergocalciferol and parathyroid hormone interferes with the development of osteopathy caused by prednisolone.

 

Simultaneous prescription of prednisolone with cyclosporine and Ketoconazole - cyclosparin (inhibits metabolism) and ketoconazole (lowers clearance) increases toxicity.

 

The emergence of hirsutism and acne is facilitated by the simultaneous use of other steroid hormonal drugs (androgens, estrogens, anabolic, oral contraceptives).

 

The simultaneous administration of prednisolone with estrogens and oral estrogen-containing contraceptives reduces the clearance of prednisolone, which may be accompanied by an increase in the severity of its therapeutic and toxic effects.

 

The simultaneous administration of prednisolone with mitotane and other inhibitors of adrenal cortex function may necessitate an increase in the dose of prednisolone.

 

With simultaneous use with live antiviral vaccines and against other types of immunization increases the risk of virus activation and the development of infections.

 

With simultaneous use of prednisolone with antipsychotic drugs (neuroleptics) and azathioprine, the risk of developing cataracts increases.

 

Simultaneous administration of antacids reduces the absorption of prednisolone.

 

With simultaneous use with antithyroid drugs is reduced, and with thyroid hormones, the clearance of prednisolone increases.

 

When used simultaneously with immunosuppressants, the risk of infection and lymphoma or other lymphoproliferative disorders associated with the Epstein-Barr virus increases.

 

Tricyclic antidepressants can increase the severity of depression caused by taking glucocorticosteroids (not shown for the therapy of these side effects).

 

Increases (with prolonged therapy) the content of folic acid.

 

Hypokalemia caused by glucocorticosteroids may increase the severity and duration of muscle blockade against the background of muscle relaxants.

 

In high doses reduces the effect of somatropin.

 

Analogues of the drug Prednisolone

 

Structural analogs for the active substance:

  • Decortin H20;
  • Decortin H5;
  • Decortin H50;
  • Medomobred;
  • Prednisol;
  • Prednisolone 5 mg of Jenafarm;
  • Prednisolone buff;
  • Prednisolone hemisuccinate;
  • Prednisolone Nycomed;
  • Prednisolone-Ferein;
  • Prednisolone sodium phosphate;
  • Sol-Decortin H25;
  • Solu-Decortin H250;
  • Sol-Decortin H50.

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Reviews (211):
Guests
nyusha
The drug is effective for its indications, but it is obligatory for the doctor's prescription, since there are so many side effects. When he was appointed to me - very quickly gained weight. Since the drug is hormonal and all the time very much like to eat, so the kilograms were added before our eyes, swelled like a barrel. Do not take risks with health and potent medicines, such as prednisolone.
Guests
ambulance doctor
Let's go through the vein in case of shock conditions. A good remedy for relief of emergency conditions.
Guests
Sasha
And whether it is possible to use Prednisolonum at an illness or a genyantritis?
Administrators
admin
Sasha, There is no sense to use a hormonal drug for an infectious disease, I will even say more - it can do harm. Probably, the doctor has appointed or nominated to you this preparation from other disease, but at a genyantritis to accept Prednisolon it is necessary with care as he can promote development or an aggravation of infectious diseases.
Guests
Masha
At the child purulent angina, together with an antibiotic have appointed or nominated prednisolonum and bifidumbacterin. Why prednisolone?
Administrators
admin
Masha, And I do not understand. If the doctor thus wanted to hedge against possible allergic manifestations of the antibiotic (once doctors in Soviet times gave such a cocktail), then this is the last century and just profanity. If your child has a concomitant disease, then the use of Prednisolone in the treatment regimen can be justified. In any case, the rationale for prescribing any medicine should be consulted by the doctor who appointed it.
Guests
Julia
Strong rash from the suppositories of Viferon, in the children's consultation pricked prednisolone, why? And is it a strong hormone?
Administrators
admin
Julia, Prednisolone is a strong hormone. They were stabbed, probably because there were fears that Quincke's edema would develop or another allergic manifestation. Do not use Viferon anymore. This medicine does not go to you (assuming, of course, that an allergic reaction has arisen on this drug and nothing else has been applied).
Guests
Inna
Mom was prescribed prednisolone (bronchial asthma, an allergy), but did not register how long to take it. As a result, I took the year exactly, but I felt much better. Now the doctor canceled the appointment, it became worse. Is it possible to start taking this medication again? Is there a time limit ?? Because newly prescribed drugs - antibiotics cause the strongest allergy, it becomes much worse.
Administrators
admin
InnaThe whole question is that hormones (to which Prednisolone belongs) can be seriously ensnared, as addiction develops to them. If the doctor canceled the drug, then began to observe and side effects of the reception. Of course, why he prescribed antibiotics as a substitute is not clear, you can see your case is complicated and do not consult in absentia, so communicate more closely with the doctor, and ask more questions.
Guests
Julia
From a severe allergy swelled all over the face I drank cetrin after two hours of worsening caused an ambulance to me in the tawigil prick and prednisolone the doctor said to drink suprastin and prednisolone 2 mg per 1 kg,and when and how many days it is not clear in the morning rose all the redness was asleep there is no itch but the nose and eyelids are the top of the bottom watery from what did not understand and what do I do not know whether to drink or not prednisolone?
Administrators
admin
Julia, The ambulance doctor should advise you to consult the therapist at the local clinic (or to your doctor), since you yourself do not have to joke with hormones, you need to look at your previous diseases and conditions associated with allergies.
Guests
Maria Sergeevna
Is it possible to take alcohol while taking prednisolone? We are not talking about the constant use of alcohol, but only about a single, we have a holiday soon and I think it's worth supporting friends or not))))) I take prednisolone for a week, prescribed an allergy effect is already there! What to do? Prompt.
Administrators
admin
Maria SergeevnaSimultaneous intake of alcohol and prednisolone increases the risk of erosion and ulcers of the gastrointestinal tract, so that friends may have fun with alcohol, and I would advise you on juice, water and other non-alcoholic drinks.
Guests
Maria Sergeevna
Thank you! I'll drink juice! :))
Guests
Julia B
To the child of 8 years, the diagnosis from year - an allergic dermatitis. Last year, after the south, + bullous dermatitis was delivered. This year came to the south on 18.07, TODAY (20) already there are small rashes, like urticaria (in the past it started with the same). I have a panic, and tickets back only to 4.08. Can I start giving prednisolone and in what dose? Cetrine does not help.
Administrators
admin
Julia BIn your difficult situation, you can recommend Prednisolone only at that dose and only if you have already taken it at home (you were prescribed an allergist or dermatologist, to which you applied last time). The second point - why are you taking the poor child to the south, if there is an allergic reaction there? Rest on your latitudes, many diseases are contraindicated to the south and nothing, resting near water bodies in their latitudes.
Guests
Nikolai
Not approached. The ulcer was sick and vomited.
Guests
Svetlana
Returning from the south on the train, an unbearable itching, diarrhea began, and at night when leaving the toilet she lost consciousness. The whole body was in red plaques and combs. At home she took cetrin, for a couple of hours it became easier. And enterofuril with furazolidone. The throat was pressing, it was difficult to breathe and swallow. She ran to the doctor appointed Prednisolone (according to the grid to decrease the application) Stugeron and Fluconazole. Prior to that, Tavegil was injected into the procedure room and what a hormone in D. Tell me, will this whole medication cocktail benefit you?
Administrators
admin
SvetlanaYou have some kind of strong or combined reaction. So to understand your specific situation is necessary with the treating doctor internally. Be sure to visit an allergist.
Guests
Jeanne
My son is 2 years old. Perhaps, after taking Ibufen, red spots appeared on his body. The allergist diagnosed: urticaria. Has registered: an zodak and a momat. For a couple of days it became easier. We went to our neighborhood, but on the way again all poured out. They called an ambulance. The suprastin and prednisolone were injected in the hospital. It's all over.The next day I poured out again. The pediatrician has appointed: 1 tablet Suprastinum 2 r. per day, activated charcoal 1,5 tab. - 3 r.v day, Prednisolone 15 td - once a day. Today is the second day. Day passes, and at night in the morning again pours out. What to do? All this began with us from August 29, 2013. Can he have such a reaction to the vaccination of the HAV, which we were given on August 22, 2013?
Guests
Maria
I took prednisolone for about 6 months, gained 10 kg. Will I be able to get back to my weight? And how much time do I need?
Administrators
admin
MariaIf you see a withdrawal of the hormone drug Prednisolone, then you can fully return to your own weight. It is possible, for accuracy, to check with an endocrinologist to make sure that there is no hormonal failure in the body. With terms it is better not to force the process of weight loss and for six months or a year the body should come back to normal.
Administrators
admin
Jeanne, With allergies it's always difficult. It is difficult to establish the cause, it is difficult to treat afterwards.Most of the diseases in general are in the idiopathic category (that is, without an established cause).

So in your case, I would start with an exact definition of what this situation could be (taking a medicine, having a vaccine, changing the food - then any small thing can help). The setting of allergic tests also helps (though not always) to determine the causes of allergic reactions. Because when the allergic process is started, it is possible to provoke external manifestations of allergy by various factors that previously could not cause an allergy. Consultation of an allergist and / or an immunologist should also help.

The pediatrician has appointed everything within its competence, there is nothing to complain about, but if the treatment does not help and the attack does not stop, then it is necessary to change the combination of drugs and remove the factors that cause the allergy.
Guests
yana
Prednisalone was prescribed a month ago (hepatitis c). The drug works, but the stomach and face are badly swollen, especially the lower part and from the muscles immediately left only the skin. Tell me, will this pass or will I remain such a rickets?
Visitors
lisa_alisa
Hello! .. Please tell me, please, and maybe because of prednisolone in pricks from a single application against allergies to stay a month for five days? .. Just the situation was strange ... I bought pills from cystitis palin, I had it allergic in the form of redness and urticaria pruritus drank suprastin and activated charcoal did not help ... An ambulance came to me from the allergy and said that it was necessary to do a prednisone even in a vein, I was against since I know this drug from a not very good side, I asked it exactly and nothing is gone? To which the doctor assured me that the dosage is small and what is this in order to remove the allergy and for some reason asked about the monthly .... And now the number of monthly a week is not there ... This is what? .. And when now wait *? ... And not what will not be serious health from one time ... Especially since I breastfeed the year ... At that time I really day after the injection expressed ... Thank you in advance.
Administrators
admin
yanaMost of the side effects caused by taking medications are temporary.With regard to hormonal drugs, which includes and prednisolone, all the more difficult and time to restore is required more, sometimes years.

By the way, considering your diagnosis, your dystrophy (decrease) of muscles can be caused by illness, and not by the intake of Prednisolone. In any case, you need to bring the changes in the body to your treating doctor, so that he consulted, given your illness and related conditions.

lisa_alisaA little bit does not fit a few moments - breastfeeding and menstruation. If you feed regularly, then hormones should block monthly, if irregularly - then this is quite possible.

The same can be said about the delay in menstruation - it is necessary to look at the next date of the onset of the next (on a cycle), if they do not go at the set time, then contact the gynecologist. It is doubtful that the delay is caused by Prednisolone.
Guests
lerok
With bronchitis the doctor prescribed 60 mg (2 ampoules at a time) of prednisolone in / muscularly for 3 days, the first time it was put, it became bad, until the loss of consciousness, now it is better to continue to put on or to give a larger dose?
Administrators
admin
lerok, I would cancel after the first injection (when it became bad), but now speak better, so you can try and put it a third time, but you need to do this under the supervision of a doctor (in the treatment room, where they can help if something happens) .

Probably you are mistaken with a diagnosis or you have one of the types of chronic bronchitis (possibly with an asthmatic component), because with acute bronchitis Prednisolone is not prescribed.
Guests
Anya
At me a hyperteriosis, antibodies 1500, the rest in norm or rate, this preparation is obligatory?
Administrators
admin
Anya, Your condition is not for correspondence online consultation, such a drug through the Internet can only appoint an illiterate doctor, only at home. The fact that prednisolone reduces the amount of antibodies produced is a fact, and then talk with your doctor.
Guests
Olya
Hello! Have appointed this drug in connection with inflammation of the facial nerve, 10 tablets a day. Very afraid to take, tell me,please, whether it is necessary? I read that after they are very recovered and do not return to the previous weight, in this regard, strong experiences.
Administrators
admin
OlyaIf the disease is serious, then drugs for treatment are prescribed serious. In any case, in your case, prednisolone is the base drug and you can not refuse it. In the issue of the adequacy of Prednisolon, and not some other drug, you need to contact your doctor if there is no trust in yours - contact another neurologist, he can tell you a more gentle treatment regimen (although not a fact, this). Do not be afraid, because someone is recovering, and someone's weight is normal or even reduced, it's a side effect, not the main one.
Guests
Elena
Took prednisolone for about 6 years, and it's wrong: morning and EVENING! The doctor did not explain how to take. Now more than 10 years I take beklazone. Now I have trouble with the skin: it is very thin on the hands and on the legs, it is easily traumatized, just torn, permanent bruises.Still the muscles of the arms and legs are very flabby, no fiz. load does not help. Is it possible to get rid of this somehow? Has forgotten: at me a bronchial asthma in a stage of remission, I know as to support myself in a normal status.
Administrators
admin
Elena, I can only advise to adjust the dosage of hormonal drugs. Judging by your problems all the troubles go from this.

Bruises can be problems on the part of the blood, coagulation may be impaired, to make an analysis, make an analysis on MNO.

Problems require a lot of consultation of the doctor with all the results of the tests and the schemes of the previous treatment.
Visitors
Taras
Clotting is not broken, there are no problems with blood, bruises only on the ground with thin skin.
Administrators
admin
TarasThen only questions with a dosage or the scheme of reception of hormones. Can overdo it. Prolonged reception of hormones in any case does not pass without a trace.
Visitors
Taras
Admission of hormones according to vital indications, everything is under control.
Guests
Lyudmila
Prompt, please, mixed MG and ML on the package in the end instead of 50 mg once a day slapped 150 (!), But I feel good.
But I have these injections according to the scheme: 1 day - 50 mg, 2 - 50 mg, 3 - 25, 4 - 25, something needs to be adjusted in case I am so confused on the first day? Can generally not put more? (((
Administrators
admin
LyudmilaBe the next time careful with hormones. Now you need to switch to the standard decreasing dosage of Prednisolone. That is, in your scheme there will be such dosages: the first day - 150 mg (it is wrong sometimes), the second day - 50 mg, 3 - 25 mg, 4 - 25 mg, etc. according to your scheme. The main thing is no longer make mistakes, but the body can not stand it.
Guests
Lana
At the husband hair drop out, on a head almost does not remain, drop out on all body. Wants to drink (without consulting a doctor) prednisolone. Question with dosage. To the doctor refuses to go categorically.
Administrators
admin
Lana, This is nonsense so you can tell your husband.If he wants to become fat impotent, with greasy skin, then go ahead. To ruin your health by the irrational intake of hormonal drugs has not been prohibited by any decrees and conventions. I even have a history of the disease before my eyes, I do not prescribe a hormone remotely to a person.
Visitors
Svetoulya
The child (4 years) has pneumonia. On the fourth day of treatment, the doctor listened to whistles in the lungs. Said that something is allergized. We prescribed prednisolone 20 mg per day for 5 days. There are no signs of an allergy any more. The child is active, is recovering. Is there really a need for taking the drug only on the basis of whistles?
Administrators
admin
Svetoulya, Only the whistles in the lungs can not be the basis for the installation of a "diagnosis" "allergized." And for the appointment of prednisolone, serious reasons are needed. For the situation as you described - I would not appoint.
Guests
Sofia
To the son of 8 months, doctors put that atopic dermatitis, then milk croup.Prescribed for 5 days intramuscularly. Is it worth it to kidnap him?
Administrators
admin
SofiaYou need to treat only what is correctly diagnosed. Such a serious drug as Prednisolone to give a small child (and also an adult too) can only be for serious reasons. Therefore, find a doctor who will put you the right diagnosis and only then will prescribe an adequate treatment.
Guests
Dmitriy
To a daughter 2 years, the itching red maculae on all body began to appear and two eyes swam. The allergist has appointed or nominated one injection Prednisolonum 25 mg v / m + 1 month Zodak. Is it worth to be afraid that one injection of prednisolone will cause irreversible effects to the child's organism (side effects will appear)?
Administrators
admin
Dmitriy, Standard with the appointment of hormonal drugs, such as Prednisolone, the doctor realizes that it can cause potential harm to the child, therefore uses this arsenal only when the other methods are exhausted or the situation is critical.

Judging by the swollen eyes, in your case there can be a critical situation when the swelling will pass to the respiratory tract and cause asphyxia, in which oxygen can not enter the child's body. So do not delay with treatment.

Qualifications of narrow specialists (allergists including) are sufficient to prescribe Prednisolone.
Guests
Alyona
Hello! My daughter is almost 2 years old. We were diagnosed with a clinical diagnosis: idiopathic nephrotic syndrome, full, peak period. We were prescribed prednisolone at 8 am - 2.5 tablets, and at 11 o'clock - 2 tablets. 1 tablet - 5 mg. Is not this medicine a lot for this age ???
Administrators
admin
Alyona, To determine the dosage of Prednisolone, it is better to indicate the weight of the child, and not the age, since the drug is titrated in children by weight. But judging by what you indicated, there is no excess of the dose in the appointment of the hormone. Take and recover.
Guests
Olga K.
Chronic bronchitis, propyl antibiotics and drugs for cough.After treatment, blood tests are even worse. Have prescribed prednisolone injections and tsikloferon. I am afraid of prednisolone - the husband from him has strongly recovered (rheumatoid polyarthritis). The truth to me only three ampoules have written out (whether costs or stands?)
Guests
Maria
At me at first the rash on arms or hand and legs or foots is not clear on what in the afternoon. Put suprastin in / m. Arriving home in the evening, my face and spasm of the larynx began to swell. She called an ambulance they gave me prednisone 90 mg IV. Then the measured pressure was high 150/80. They gave the Caventon a language. After 15 minutes, the pressure dropped to normal, the swelling passed but the feeling of lump left in the throat. I went to bed closer to the morning again woke up with a feeling of strangulation, the voice was not there again called the ambulance they put me again prednisolone, but already 60 mg IV and tavigil IM. And they told me to go to the therapist tomorrow and go to the allergist. In the morning, I got up from my face, the swelling was gone, but the itch became all over my body and the blisters appeared. having come to the allergist. She told me everything. She has appointed or nominated to me again tavigil and prednizalon v / m, and for the night zirtek. I began to tell her that I now do not recommend gynecologists to take any hormones.The allergist said that it is necessary to put it. I'm afraid to put it. when the speed that put me immediately there were pains in the lower abdomen. Is it worth it to put prednisolon?
Administrators
admin
MariaYou have a serious problem. I see in your history first of all an ambulance defect that did not take a person to the hospital with a beginning laryngeal edema from which you might well have died, and there you could conduct an initial screening test to determine the cause of this condition. But it's okay, now it's essentially a problem.

Probably from Prednisolonum you should not refuse and here it is necessary to look what problem on gynecology at you. In any case, the priority in treatment is life-threatening, and in your case it is an allergic reaction (until you know your gynecological diagnosis), in any case, before the treatment begins, go to the gynecologist and describe the situation that has arisen.

Olga K., To be afraid of hormonal preparations it is not necessary. Especially if you have already been treated by some means earlier and passed the tests. If to you for the first time prescribe Prednisolonum without life-threatening conditions,then it is worth not to trust. And so it is necessary to take the treatment prescribed to you, so as not to aggravate the progression of the disease.
Guests
Michael
Have appointed or nominated prednisolonum and for the first time have stuck it or him, it was wildly sick. He himself is so sick or wrongly pricked?
Administrators
admin
Michael, With the introduction of Prednisolone intramuscularly, pain can be observed both with administration and some time after. The intensity for each of the sensations will be different. But if the pain persists for a long time after the injection, it can be assumed and improper introduction and development of the abscess at the injection site.
Guests
Guzel
How does prednisol affect hemoglobin levels?

Good afternoon.
Papa has been drinking prednisone for a year from ulcerative colitis (NNC), which is characterized by frequent diarrhea with an admixture of blood.
The day before yesterday, my father began to drink a smaller dose of this drug (three tablets a day), as a result, his health worsened. The diarrhea became more frequent, empty desires, stretching downwards, appeared, blood became more and more, weakness, my father became gloomy and in the morning he could not stand it and drank 6 tablets of prednisolone, then today at dinner 4 more pills.In total already 10. In the evening plans 2 more tablets. The condition as soon as it improved, the diarrhea ceased, cheerfulness appeared.
QUESTION: I ask you to analyze this situation. What was it? Dependence on the drug? How to stop drinking this drug while maintaining health? And how prednisolone affects hemoglobin levels. he has a raised papa = 167. Thank you so much!!
Guests
Nora
Hello! My mother was diagnosed with Sarcoidosis. The respiratory rate increased to her appointed prednisolone. Takes more than a year. The face was swollen and her weight gained. There was chronic heartburn and a week passed a leg hurts or bones of one side. She has a fear, she worries that she will stop walking at all. Tell me, please, can she refuse prednisolone? And it seems to me that the doctor has everything on the drum. In addition to prednisolone did not offer anything. Especially this drug is not canceled, type like you want to live, take it constantly. Can not you live without PREDNISOLON !! ((I'm very upset ((Thanks
Guests
Ekaterina Petrovna
What lek-va to drink when injected Prednisalon to protect the stomach, joints and genitourinary system?
Administrators
admin
Ekaterina PetrovnaIf at the beginning of treatment with your health everything is in order, then I do not appoint any additional safety appointments. There is no sense in this, in addition, the appointment of a large number of medicines at the same time can adversely affect the drug interaction between them with each other. If you already have problems with the specified systems, then you need to continue to take the standard treatment of these diseases, naturally before starting treatment, see how the drugs interact with Prednisolone.
Administrators
admin
GuzelIn principle, I do not know the specific instructions about hemoglobin in Prednisolone. The level of glucose in the blood can be increased by increasing the intake of glucose from the liver into the blood, it can still change the blood formula, but again not hemoglobin.

As for the situation described by you, you can see that it is probably too early to cancel a hormone, since the underlying disease makes itself felt. The possibility of gradual cancellation will probably appear in the future, but not now.If the prescribed course of treatment has already been completed by the doctor, then it is necessary to apply for a second consultation, since Prednisolone is a strong medicine and you do not need to take it yourself.

Nora, Sarcoidosis is a complex disease because until the end of the cause of its occurrence are not identified and everything is at the level of guesswork and assumptions. That is, the version of why it appears is, but it is specifically because of what it occurs (mycobacterium tuberculosis, viruses, other bacteria, immune system problems) is unknown. Therefore, the difficulty with treatment. In our TB dispensary it is also treated with schemes involving Prednisolone and positive dynamics. But the side effects of this hormone are, if the medicine is required by the indications so simply not canceled and replaced.

If there are communication problems with the doctor, then they need to be adjusted or replaced by a doctor for another, more adequate. Independently your problem by online consultation is not allowed, the disease is serious.
Guests
Nora
Thank you for answering my question. Yes of course they changed the doctor, everything was done anew. But there was already a different diagnosis. Bronchial asthma.They, of course, stopped prednisolone and were treated with other drugs. Three months later, the temperature did not drop. And immediately I had to take Prednisolone. (((That's why I was worried, 11 days today, my leg hurts, it says it hurts when I walk.
Administrators
admin
Nora, And what is this creepy unprofessionalism, when sarcoidosis suddenly jump to bronchial asthma? After all, the diagnosis of sarcoidosis is made quite easily on the basis of specific granulomas, which are found during X-ray examination, in a controversial situation they can make a biopsy and confirm the diagnosis.

In general, your mother's health problem is greater in the defects of medical care in Russia in general, and not in the wrong diagnosis or treatment. And the pain in the leg, most likely, is not connected with taking Prednisolone as I see this situation remotely. Give a biochemical blood test with all markers of inflammation, rheumatoid factor, anti-streptolysin. Do an X-ray examination of the joints of the affected leg, the reason is most likely in the joint group, rather than Prednisolone.
Guests
Marina
There was a strong allergic reaction with swelling of the throat. In the hospital, prednisolone was dripped the first day of 90 ml, the second-fourth day twice a day for 90 ml, the fifth and sixth day once a day for 90 ml. In parallel, prednisolone is given in tablets of 20 mg per day for ten days. Do I need to drink P. after a discharge with a lowering regimen?
Administrators
admin
MarinaLife-threatening conditions are treated first at home, and then at home. If doctors have written out Prednisolone on the house - it is necessary to drink. This is better than dying from a sudden swelling of Quincke or another allergic reaction. Treatment of a serious allergy is complex and occurs gradually, including other antiallergic drugs (antihistamines, hepatoprotectors, adsorbents, etc.).
Guests
Marina
The fact of the matter is that the doctor did not prescribe to drink Prednisolon at home. No downsizing scheme. Just canceling everything. I'm worried if it can be so abruptly abandoned. Do we need a reducing regimen after the above treatment in the hospital?
Administrators
admin
MarinaAs I remember your question, you take Prednisolone for ten days. In your case, you need a gradual decrease in the medication you use. It is permissible to give up Prednisolonum concomitantly, if you take it for at least three days, but not 10. It is necessary to consult a doctor to clarify the treatment scheme.
Guests
Marina
Thank you very much for your answer. What is fraught with a sharp throw? The attending physician at the hospital said that you do not need to drink anything else. Perhaps, I will go to the doctor in the district clinic.
Guests
Marina
Thank you very much for your answer. I clarified with the attending physician in the hospital, she said that gradual reduction is not necessary. I think I'll have to see a doctor at the polyclinic. What is fraught with a sharp throwing P. after ten days of admission?
Visitors
Svetik
Good afternoon! To me of 28 years, I am ill 4 years sarcoidosis of lungs 2 st.chronicheskoe a relapsing current, I accept a preparation prednisolon too 4 years under the scheme or plan of 25 ml. per day (5 tons) followed by a 1/4-fold decrease in 10 days (the total rate is 9 months).With the use of this drug, edemas appeared on the face (cheeks and a second chin appeared), constant headaches, eyes ache, grew on the neck from the back of the hump, the abdomen grew, stretch marks and varicose veins appeared on the legs, recovered from 45 kg. up to 70 kg., constant fatigue, when I take this medication from the side of the disease I feel fine, but I do not want to live a general condition, but as soon as I reduce it to 1/2 t. a day everything passes, but the disease returns, tell me what to do , I consist on the account at the lung specialist, whether there is a replacement of this preparation?
Administrators
admin
MarinaIf you suddenly stop taking Prednisolone, then perhaps the development of withdrawal syndrome: anorexia, nausea, inhibition, generalized musculoskeletal pain, general weakness, as well as an exacerbation of the disease, which was prescribed prednisolone. Many patients note a very painful sensation as a result of a sharp abolition of this hormone, so I would ask my doctor and the treatment plan.

MarinaProbably the doctor considered the course fleeting for your condition.Maybe he's right, although they certainly pumped you Prednisolone well. The main thing is that the allergic reaction is not returned. But go to the polyclinic, let them see what the doctors from the hospital wrote there, maybe less prednisolone was prescribed for the appointment than you wrote, this also happens.

Svetik, I'd be glad to help, but Sarcoidosis is not a common disease, plus it shows successful results on Prednisolone. So address to the lung specialist, something new has appeared in treatment of this disease, even experimental. Age at you young, probably to something and you will come, considering by-effects of a hormone. Therapists do not treat this themselves.
Guests
Marina
Yes, the attending physician said that the course is short and there will be nothing after the cancellation. Now I do not accept P. the third day. After lifting the allergic reaction returned, though not as much as it was at the beginning, but decently, throughout the body. From time to time heart palpitation. And also I either caught a cold in the hospital, or an allergic cough developed, I do not know, in general, the condition is classic influenza with temperature (for me it is absolutely uncharacteristic, because I never get flu).There are no other symptoms of withdrawal. In the clinic went, the therapist without a sound wrote a referral to an allergist in monica. The district endocrinologist slightly ofigela from that after such doses the decrease was not appointed or nominated and has told or said to run to the endocrinologist in moniki stvoprimshchas. Both doctors in the clinic are surprised that after this treatment the allergy has not passed. No recommendations were given. Doses P. indicated correct, I fotkala my card in the hospital, there all legibly written.
I correctly think, that the allergist will appoint or nominate necessary analyzes and inspections? Is it necessary to pay special attention to something or to ask separately about some surveys? Whether there is a necessity to hand over analyzes on hormones of adrenals after the spent course of treatment of P.?
Administrators
admin
Marina, Adrenal hormones do not need anything - it's superfluous. To the allergist to go necessarily, on Prednisolone relapse is not an ice. And tell the doctor everything you remember, including allergies from early childhood, and that preceded the attack. Let's hope everything will be fine.
Guests
Marina
The allergist did not say anything new in fact. Hives of unknown origin. Drink antihistamines and keep to a diet until it does not pass. No tests were taken, no tests were scheduled. As for prednisolone, it seems to be reassured that there should not be a short course from the short course. The spots do not pass and itch, but the general condition is better, the cough is less, there are no other consequences of the cancellation yet.
Guests
Valentina
Kind time of the day! My mother was prescribed prednisolone in connection with the detected disease - pneumosclerosis, pulmonary fibrosis. After a long reception of the drug without positive dynamics (according to the results of tomography), the dose was increased. Of course, all the side effects were on the face. But the result of treatment of the disease was not, progressing shortness of breath, choking cough, a new darkening on the lung, etc. Mom, in search of a panacea, turned to alternative medicine (although this is not even medicine at all) - a sorcery. The folk healer managed to prescribe dietary supplements, conducted a course of "treatment", left the prescriptions (certain exercises at a strictly prescribed time) and strictly forbade the taking of any tablets. Believing him, (not realizing the consequences), she abruptly stopped taking Prednisolone. It was very bad the first day, the next it seemed easier, but then it became hard again. At present, it carries the whole weight of a sharp rejection of the hormone - pain in the muscles, joints, the desire not to move, to lie - all of what I am now reading in the reviews. What to do? A week has passed since she left. Maybe she can start drinking hormone again. She planned to look at the effect in a month, then go through the examination, go to the doctor in charge. But I'm afraid of irreversible consequences that may already have begun. Tell me, please, this disease can progress with double force under such circumstances. Until I sounded the alarm personally to her, I did not want to undermine the forces of auto-suggestion, which, as it is known, can create a miracle, but I myself will not find a place, suddenly we lose precious time. I will be very grateful for the answer.
Administrators
admin
Valentina, The hormone itself does not begin to be taken anew - the body can generally disagree on this, but it is better to contact a doctor right away.Apparently you need another doctor, lung specialist, if the existing one is only trying to increase the dose of one medication, on which the disease still progresses, in spite of the ongoing treatment. The forces of autosuggestion with your disease will not help, you need adequate therapy. It is necessary to watch the situation internally.
Guests
Valentina
Thank you very much for your response. Indeed, it was not known how to rely on such a serious disease. Such mistakes, illiteracy can be expensive. Thanks again.
Guests
Vera
Yesterday my son had a rash on his face, cough, went to a polyclinic, the doctor advised me to make 2 cubes of prednisolone, today my son has a temperature of 37.2. Strong! a headache, a vomiting (water), prompt please, this preparation could not give such reaction? (To the child of 6 years, in 1 year put intracranial pressure)? Thank you.
Administrators
admin
Vera, You better tell me on what basis the doctor prescribed Prednisolone? From your words, I did not see a reason for this.Can the child have already been diagnosed differently, except for increased intracranial pressure? Beginning allergies, there may be a laryngeal edema was (changes in voice, hoarseness), then it is absolutely fair and then the hormone will not go to the sentiments or not, they are pricked and that's it. Life is more important. The temperature of Prednisolone hardly increased. Examine the child as soon as possible.
Guests
lily
Good afternoon. I have Polymyositis and Primary Hypotritis. severity. The neurologist prescribed Prednisolone 50mg in the morning to 8.00, Omega 20mg 2 times a day. The endocrinologist prescribed L-thyroxin 100. Both drugs are hormonal. Tell me please whether they can be combined. Thank you.
Administrators
admin
lily, All the medications you specify are combined. At least, there are no indications of the side effects of all three mutually in the corresponding instructions. The only thing I can advise you still periodically to take biochemical tests, including the level of glucose in the blood (sugar), because the metabolism of your body due to the appointment of these drugs will be changed.
Guests
Victor
Good afternoon. Two days ago I was discharged from therapy. Diagnosis: psoriasis, psoriatic polyarthritis, moderate degree of anemia, osteochondrosis of the lumbar spine, mycosis esophagitis, chronic gastritis, bilateral nephroptosis and yet found one bad thing, that is, they found AIDS (doctor's illegible handwriting). Have written out many different preparations including prednisolone 5 mg. 2 tablets after breakfast. The doctor said that it is dangerous to increase the dose because of AIDS. Is the doctor right?

And if you can help with the schedule of taking pills. Table of tablets: Prednisolone 2 tablets after breakfast (not indicated how many days to drink), Omeprazole half an hour after taking prednisolone, Fluconazole for 20 days capsule, NSAID I was used to Diclofenac 100mg for pain, Pentoxifylline 100mg 1 tablet 3 times after food - 1 month, chondroprotector Arthra 2 tablets, vitamins (B6, B1, C, E). Help please make a schedule. Such a huge number of tablets. thanks in advance.
Administrators
admin
Victor, Sorry for the long answer, since your case is not trivial, I had to work with him longer than with other questions.

About the restriction of the use of the drug Prednisolone in HIV infection (AIDS), this can be justified, since the hormone has a pronounced immunosuppressive effect (suppresses the response of immunity, therefore it is used to treat inflammatory diseases and you, I suspect, was prescribed for polyarthritis treatment). Its use in this concomitant disease in large doses is undesirable (with HIV infection, the body already suffers from immunodeficiency and should not be driven harder). This drug should be canceled by a doctor, gradually in a stepwise scheme, so that there is no relapse, but it may take a long time to take.

The moment that I did not like in your treatment scheme - there is no specific treatment for HIV infection (antiretroviral, immunocorrective, etc. drugs). This is your basic therapy, although at different stages of the development of the pathological process it can be prescribed by courses or absent, but how to act in your case the doctors should have explained.

According to the scheme of taking those medications that you prescribed there are no difficulties:
Prednisolone and Omeprazole are clearly painted and taken in the morning.
Fluconazole can be taken before meals at any hour, most importantly, it should be the same time.
Pentoxifylline after meals 3 times a day.
Taking Arthra is also not dependent on food intake and does not interact with other medications, so choose a separate time for this drug and take it on the same day every day until the end of the course.
With Diclofenac it is necessary to be extremely cautious (in this scheme I would say that it is superfluous, but given the severity of the concomitant diagnoses, we will conditionally leave it). Take it better after eating and strictly monitor the state of the gastrointestinal tract, as in conjunction with Prednisolone can cause severe disturbances in the mucosa of the stomach and intestines with the development of ulcers and / or bleeding.
Vitamins can also be taken after a meal, but they do not interact with other medications.

I would also like to wish you success in treatment and more is in contact with specialists, as now they guarantee the preservation of your life and its quality.
Guests
Vika
Hello! I can not breathe the air to the very end, how I suffocate, all tests are normal - thyroid, heart, hormones, blood test, urine, everything was checked for allergies, everything is OK! Was at six doctors, diagnose VSD, a neurosis, speak,that it's respiratory spasms! Such at me was in 15 years, have cured - 10 days pricked - in the morning prednisolonum and eufilin, in the evening eufilin! Now to me of 28 years, the first doctor has appointed or nominated treatment - 5 days prednisolon on 60, 10 days of calcium gluconat, calming or abirritating and vitamins with B6, treatment has almost helped or assisted, but in a week again all anew has gone! Other doctors prescribed such medicines as actovegin, cocarboxylase, mexidol, tranquilizers, soothing, the treatment almost did not help! I went to the first doctor, he prescribed me - prednisolone 60mg 10 days, nicotinic acid 3 cubes / m - 10 days, vitamins B1 and B6 a day later to stab and soothing! Is this treatment correct? And in general, with the VSD appoint hormones, some doctors simply, when they find out that they've been stabbing my hormone, they say that it was useless! This state has not been going on for 4 months.
Administrators
admin
Vika, VSD hormones naturally no one heals. If the problem is in the lungs and there were already many doctors, then the last is always to pass a specialist in lungs - a pulmonologist.

About treatment, most likely, there is some hidden inflammatory process,although the analyzes say everything is clean or maybe your gasping as a harbinger of bronchial asthma (for this you need to measure the function of breathing, before the examination the pulmonologist should prescribe this examination). In any case, before treating it is not clear what, it is necessary to get to the truth and treat the disease intentionally, and not to drive the body with hormones.
Guests
Vika
Thanks for the answer! They do not tell me that the problem is in the lungs, when I ask if it's asthma, the doctors say that it's not exactly, they say that at least some wheezing in the lungs would have cough even a little! I will pass this analysis and pulmonologist! Hormones it is better not to prick? Can they hurt? Tell me, can I suffocate until I find out the reason?
Administrators
admin
Vika, Hormones can be stabbed when there are good reasons for this, but at a young age to have the potentially possible side effects of taking hormones and suffer in vain if the cause is different. Pulmonologist and additional research you need to go as soon as possible.And about suffocating, it is better for doctors to ask who is watching you (the one that is the most adequate). Serious health problems are not solved on online consultations, I will not take sin upon myself.
Guests
Vika
Thank you! Prompt, and with what this hidden inflammatory process, what organs can be connected?
Administrators
admin
Vika, Judging by the symptomatology, most likely in the lungs, therefore, I advise you to consult a pulmonologist. But very similar to the precursors of obstructive pulmonary disease (obstructive bronchitis, bronchial asthma).
Guests
Irina
Good afternoon. For several years I have been suffering from seborrheic dermatitis on my face. The dermatologist except for a cream and ointment akriderm nothing appointed or nominated. How harmful is this hormone and does it help with my disease?

admin, The drug Acriderm is present in the Directory. Please add questions and feedback to the relevant products. Seborrheic dermatitis in indications for use in this drug is absent.
Visitors
cucushcka.75
Good afternoon! With intravenous administration of prednisolone (prednisolone 50 mg saline up to 10 ml.) When the blood gets into the syringe (checked if the vein did not come out) the solution as it thickened and was introduced with great difficulty, and then did not even enter . Why? I made a mistake? I'm honey. sister, your answer is very important to me.
Administrators
admin
cucushcka.75, It seems all right. Why thickened is not clear. All the ingredients were fresh? The water is heated to 37 degrees or even to the ambient temperature? If everything is so, then what is the reason for the thickening is not clear to me.
Guests
Nat1
Hello! Tell me, please, what dose of tablets of prednisolone can be drunk once, to knock down the swelling of the quinckle when the urticaria exacerbate. At me a urticaria against a background of a thyrotoxicosis, an exacerbation each time before a menses, constantly fast to cause it would not be desirable (certainly if absolutely an extreme case that I shall call). 2 months this infection already and 1 time an exacerbation in the form of an edema of eyes and labiums, fast - suprastin 25 mg and prednisolone 50 mg.Is it possible to drink tablets of suprastin and prednisolone and in what dose to bring down? Thanks in advance.
Administrators
admin
Nat1, No doctor tells you the dosage, because Prednisolone is a serious drug, and Quincke's edema is the most serious complication that caused the death of many patients. The point here is not in your thyrotoxicosis or menstruation. You need advice from an allergist and possibly a basic therapy for an allergic disease, which you certainly have. Maybe for food, maybe for drugs. It is necessary to search for the cause of your condition and to be treated, and not to write off it for indirect reasons.
Guests
Nat1
I wrote to you earlier from 29,10,2014. I also observe an endocrinologist (I drink tirozol for 2 months with a decrease in the dose already 5 mg, the scutellum comes back to normal) and an allergist. The allergist has diagnosed as well as the endocrinologist, that this urticaria of an autoimmune origin (a chronic urticaria on a background of a thyrotoxicosis, hormonal), there is a probability, that when hormones shchitovitki come to norm or rate then the urticaria will pass or take place.I treated urticaria with antihistamine and fexadine 180 mg, and cetrine 10 mg, and suprastin, and loratadine, but it does not really help anything, it can, if sometimes it's an itch.

She began to fall asleep in the morning face and for the day 2 before menstruation edema (after the menstruation begins, there are no rashes on the face, only on the body), an allergist, tried to drink prednisolone 15 mg with a dose reduction, , even after the drug was discontinued it just happened one week before the menstruation again began to pour on the eyes and lips and face and one fine morning the lips and eyelids swelled, the ambulance - suprastin and prednisolone are put. I visit again an allergist and she says that there may be an exacerbation before menstruation, tk. I have hives connected to the hormonal background, as she explained to me. She prescribed me montelukast 10 mg 1 time before going to sleep for 3-4 weeks along with antihistamines, I asked her about prednisolone tablets whether she could swallow the swelling, she answered that it is possible, but about a single dose (how much to drink tablets , so that the edema is released, if it already does not help for some time, then call an ambulance) I missed asking, they started talking. And I will not go to her soon, and there is no such opportunity to go to her every week. So I'm wondering if you can help me in this matter. Allergies NEVER suffered for anything. Thank you in advance.
Administrators
admin
Nat1In emergency conditions, a single dose of Prednisolone is 20-30 mg, followed by a decrease in dosage (which in your case is irrelevant, since it is assumed a one-time intake). You ambulance gave 50 mg, in principle, this option is also possible, but I would still with smaller doses started. In any case, it is necessary to obtain an opinion of an allergist, since this situation will turn out to be unclear in the future.
Guests
Lena
Hello, daughter, 2 years old, lay in a hospital with a severe allergy, something similar to hemorrhagic vasculitis, intravenously injected prednisolone, pentussin, all through a dropper, wrote and wrote us a scheme for reducing prednisolone, by the floor of the pill every 3 days, it turns out we will drink it where then 2 weeks approximately. Along with prednisolone, aspark and finontodine and zirtek were prescribed, I have a question whether it can all be taken together, and what side effect do these drugs have? I'm worried because child small.Write, please about these preparations. And prednisolone.
Administrators
admin
LenaIf you have prescribed Prednisolone, then the child had not a banal allergy, but a serious, bordering life condition. Yes, I do not want to take a hormone at any age, but if there is a choice of life with a hormone or death without it, I will choose the first.

Any medicines have side effects, and you have been prescribed a whole treatment complex, so you should monitor your child, changes in his behavior and state of health and immediately inform the doctor in charge, the pediatrician about the changes that have occurred. In the instructions a lot of things are written, but all this pobochka not necessarily manifested, but has a frequency of 1 to 10 000, per 100 000 people, that is the probability. You need a child to be treated, but not bother searching for dirty tricks.

Your medicines are compatible with each other. And even for the protection of the gastrointestinal tract, famotidine (probably you have incorrectly written the name) is appointed correctly. Although the instruction prohibits the use of Famotidine for children under 3 years of age, but this is because the child may be suppressed by a pill before the specified age and it will be necessary to triturate it into powder. I have no complaints about this treatment. Now the main thing is to help.
Guests
Paul
Good afternoon! I had an acute respiratory disease, I had cough, fl uurography and ROE analysis - everything was normal, but I was forced to drink Zitrolid and expectorant, the cough did not go to the end, but it became better, I decided to try ACC - the cough increased, but did not expectorate, today went to reception to the pulmonologist, diagnosed Acute Bronchitis and appointed Lazolvan 10-14 days and Prednisolone 5 mg 3 times a day for 5 days. Should I take prednisolone? She assured that nothing terrible with such short terms of admission is not present, but having looked at the list of collateral - I'm shocked ...
Administrators
admin
Paul, For the treatment of acute bronchitis no one prescribes Prednisolone, with this disease it is contraindicated. You need to understand with your doctors what is your specific diagnosis, that in the analysis of the blood, that on the x-ray of the lungs. If there are problems with breathing - check the respiratory function of the lungs (HPH, etc.). Or do you come across illiterate doctors with such treatment schemes, or do you say one thing, but write a different diagnosis, but I consider this to be a violation of ethical norms and patient rights.
Guests
Lyudmila
Hello my daughter 4 years, about 2 weeks ago we were taken away at night to the ambulance in an allergic center with a sharp severe urticaria, tk. went swelling. There, for 5 days, 2 times a day, injections of prenisalone were given. We were discharged, we are already at home for a week, but the question remained, how can this course affect the daughter in the future? Can we go through some additional tests to make sure that everything is fine? I understand that in our case, without this drug simply could not do?
Administrators
admin
LyudmilaIf you were brought to the hospital and there was not a one-time course of treatment with Prednisolone, then the condition was critical and threatening the life and health of the child. As for additional tests - take care of money, most likely you will need them for consultation of an allergist and subsequent treatment (although a child can outgrow his allergy, this also happens). It makes sense to worry only if there are any unusual changes in the appearance and behavior of the child (skin discoloration, itching, increased or decreased body weight, anxiety, etc.).If you have enough money, you can take tests for a mineralocorticoid group of hormones and ultrasound of the abdominal cavity, but I would save the finances.
Guests
Alyona
Good afternoon! Tell me please. The endocrinologist has diagnosed the Subacute thyroiditis and has appointed or nominated Prednizalonum 2 tab. early in the morning, and 2 tab. by 12 o'clock. Is it possible to replace this drug with something else? Very much I am afraid of hormones ...
Administrators
admin
Alyona, Unfortunately no. You can replace only synthetic analogs, these will be the same hormones in their action. To be afraid it is not necessary, if the doctor to you has appointed or nominated a hormonal preparation, means, without this appointment to not manage. And for anti-inflammatory effect in general, there are no medications for Prednisolone.
Guests
VDanilenko
Good afternoon! 3 months ago I had a subacute thyroiditis, the endocrinologist prescribed treatment with prednisolone. Initially, there was a course - 6 tablets, 2 at 8 am, 2 at 12, and 2 at 4 days. Then went on to decline, somewhere in a month. Now I have 3 tablets, 2 in 8, o.5 in 12 and 0.5 in 4 days. Recently, the face swells very strongly, a second chin appeared, and fats began to be deposited in incomprehensible places.Tell me, how soon can I return to my previous form and what do I need to do? Very worried about the second chin and excess weight. Does it make sense now to go to the gym or do this after the complete cessation of the medication?
Administrators
admin
VDanilenkoIf excess weight is a consequence of hormonal problems, then it will be impossible to solve this issue by diet or exercise in the gym - the problem arises at the level of metabolism. Taking Prednisolone can lead to the appearance of excess weight. Therefore, the scheme of action is that if after the end of taking the medication the weight within a month or two will not return to normal (but after the treatment it is already necessary to eat a balanced diet and metered physical exertion, that is, to watch for yourself), then it makes sense to contact the endocrinologist for the delivery of tests on hormones and look that could break, including because of reception of Prednisolonum.
Visitors
VDanilenko
Thanks for the answer! I ask you to clarify why, when the drug was abolished, edema only increased, initially on 6 tablets the face was not so round, now on 3 tablets, the cheeks can be seen almost from behind.And I would like to know how quickly side effects go and how individual it is?
Administrators
admin
VDanilenko, I have already painted everything in detail. Puffiness happens and in standard cases passes or takes place for a month-two after a canceling of a preparation. If during this time does not pass, you need to be examined and find the cause of the appearance of edema, perhaps something broke down in the body because of the hormone or in general these are different things, this also happens.
Guests
Irina
Good afternoon! Have appointed or nominated to accept Prednisolonum 3 times a day (before drank two times morning / evening) - 5 mg-2,5mg-2,5mg. What time is it better to take it?
Administrators
admin
IrinaSince the drug is taken during or immediately after a meal, tie the medication to breakfast, lunch and dinner so that the intervals between meals (and accordingly Prednisolone) are approximately equal in time.
Visitors
ASIA
Hello. To the child 1 year 11 months. the temperature was 39 and the throat was red. The pediatrician diagnosed acute.pharyngitis. Treated "Cefriaxone" and the temperature dropped to 35 and diarrhea. Then they prescribed amoxicillin and diarrhea, and the child was covered with red spots. They said - hives. Began to prick tavegil and prednisolone. Now the spots are gone, but at night the baby cries, does not sleep well, scratches hands and feet. Tell me, please, are they being treated correctly? Is it possible to prune prednisolone at this age? Earlier, I was not seriously ill, did not take antibiotics. Thank you.
Administrators
admin
ASIA, And did not understand why after Ceftriaxone was prescribed Amoxicillin, because the indices, judging by everything, were already normal and the temperature dropped. Diarrhea was treated with Amoxicillin? Then this is the height of stupidity. Then, naturally, antiallergic treatment was prescribed (Prednisolone can be given to children if the condition threatens life and health), which, judging by the residual symptoms, did not give the desired results, or some skin problems have already begun (as indicated by the itching of the skin). My advice to you, find a competent allergist and continue treatment with him, the situation is ambiguous. Perhaps, residual events will pass by themselves, but this is no reason to do nothing now.

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