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Is it possible to divide the tablets and how to choose the right dosage? Is it possible to open capsules and use powder in them to prepare a suspension?

Is it possible to divide the tablets and how to choose the right dosage? Is it possible to open capsules and use powder in them to prepare a suspension?

Modern medications usually do not require any division. I define this very simply if the tablet has a dividing line in the middle, then you can divide if there is no such feature, then the tablet is indivisible and you need to look for other dosages of this medication, as you will not be able to divide it accurately in half. Also, instructions for smaller dosages (for example, for children) are indicated in the drug instructions, provided that there are no smaller dosage forms, and they are indicated in the instructions.

 

Composite drugs that can contain two or more components in their composition are also not recommended to divide or take double doses, since additional components may contain different dosages. For example, antibiotic Amoxiclav contains in its composition two components: Amoxicillin and Clavulanic acid, but in different dosages of tablets, contains a different amount of these components.

 

There are the following dosages: 250 + 125 mg (250 mg of Amoxicillin and 125 mg of Clavulanic acid), 500 + 125 mg, 875 + 125 mg. It's natural for people to question: if there is no dosage of 500 + 125 mg in the pharmacy, can a double dose of 250 + 125 mg be used? The answer: no, it is impossible, because by Amoxicillin we go to the desired dosage (500 mg), but for Clavulanic acid the excess, instead of 125 mg, 250 mg will be obtained, the final tablet will be 500 + 250 mg.

 

The difference is obvious, it is also impossible to predict the effects. Therefore, always follow the dosage regimen prescribed by your doctor. There is no medicine in one pharmacy - go to another.

 

And do not try to replace drugs with cheaper generics, as well as non-obvious benefit in terms of price, can adversely affect recovery. After all, not always the substance for such drugs is completely identical to the original, plus additional components from manufacturers of cheap medicines, may also be of a worse quality than the original.

 

About opening the capsule and using powder to prepare the suspension.This is often like making moms for their children. This is also an incorrect approach. Capsule largely protects the contents from the acidic environment of the stomach, where the drug can break down or modify their properties and breaks down in the alkaline environment of the intestine where the drug active ingredient is freely absorbed and starts acting. Thus, the preparation of the suspension from the components of the capsule is incorrect.

 

There are preparations in the form of dispersible tablets (antibiotics Flemoclav solute or Ceforal solutab), so they can be dissolved in water and use the resulting suspension for use in pediatrics or in people who can not swallow large tablets. But this is a special case, also mentioned in the instructions to these drugs.

 

I want to believe that now there will be less questions about the division or multiplication of dosages of tablet formulations, as well as the use of capsule contents for the preparation of the suspension.

Reviews (7):
Visitors
oksana30
Good evening! Tell me, please, what to do.The doctor prescribed a dosage of 250 mg / 125 mg, 3 times a day, I bought them, coming home mixed up with another jar! 500mg / 125mg (they stood side by side on the shelf in the same package, and they still have a shelf life of up to 12 months 2015) to a child of 10 years old, weight 38 kg, what should I do next? How to give in the morning. Thank you in advance!
Administrators
admin
oksana30, The name of the drug is not indicated and it is better to ask this question to a specific drug, and not in the information topic, where I even can not understand what kind of medicine is involved. I sense a sensation in the morning that it is an antibiotic called Amoxiclav or Augmentin, but I will not predict it.
Visitors
oksana30
Sorry, the first time on this site is the antibiotic Amoxiclav.
Administrators
admin
oksana30, Here's the question for Amoksiklavu and ask. Many people, I want to believe, will be interested in the question and the answer to it, but in another topic it is of no interest to anyone and nobody will see it here.
Guests
Milena
What a nonsense.Clavulanic acid in different doses of antibiotic, contains a different amount. It depends on what dose the doctor appointed. 875/125 it is impossible to divide precisely, all the others are possible. Read the instructions before taking. And before you write this, read the instructions.
Guests
Milena
Sorry. I mean Flemoklave solute.
Administrators
admin
Milena, Less emotion and more common sense. For this, in each tablet with a combination of amoxicillin and clavulanic acid and a different amount of clavulanic acid in order to select the required dose by the amount of amoxicillin. And nothing special about Flemoklav is there, the same different dosages of tablets for different regimens and a suspension for children, in which the recalculation goes for amoxicillin and the weight of the baby. These tablets are indivisible.

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