Galazolin - instructions for use, analogs, reviews and release forms (nasal drops and nasal gel 0.05% and 0.1%, spray) for the treatment of the common cold, sinusitis, pollinosis in adults, children and pregnancy. Composition and habituation

In this article, you can read the instructions for using the drug Halazolin. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Galazolin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Halazolin in the presence of existing structural analogues. Use to treat the common cold, sinusitis, hay fever in adults, children, as well as during pregnancy and lactation. Composition and addiction to the drug.

Halazolin - Vasoconstrictive preparation for topical application in ENT-practice.

Alpha-adrenomimetic from the group of imidazole derivatives. In low concentrations it acts on alpha2-adrenergic receptors, in high concentrations it has an effect on alpha1-adrenoreceptors. With topical application causes narrowing of the blood vessels, which leads to a decrease in edema and hyperemia of the mucous membranes of the nasopharynx and a decrease in the amount of discharge, to facilitate nasal breathing.

The drug starts in 5-10 minutes and lasts for 5-6 hours.

Composition

Xylometazoline hydrochloride + excipients.

Pharmacokinetics

When the drug is used in recommended doses, Xylometazoline is practically not subject to systemic absorption, so there is no data on the pharmacokinetics of galazoline.

Indications

• acute rhinitis of viral or bacterial origin;
• allergic rhinitis;
• acute and chronic sinusitis;
• Pollinosis;
• otitis media (to reduce the swelling of the nasopharyngeal mucosa).

Forms of release

The drops in the nose are 0.05% and 0.1%.

Nasal gel 0.05% and 0.1%.

Other dosage forms, whether spray, aerosol or ointment, do not exist.

Instructions for use and how to use them

Nasal drops

Galazolin in the form of drops 0.05% prescribed to children aged 2 to 6 years 1-2 drops in each nostril 1-2 times a day.

Galazoline in the form of drops 0.1% is prescribed for adults and children over 6 years 2-3 drops in each nostril 2-3 times a day.

Gel nasal

Halazoline in the form of a nasal gel 0.05% is administered by administering to children aged 3 to 6 years, 1 dose (1 injection) into each nostril 1-2 times per day. Children aged 6 to 12 years are prescribed an average of 1-2 doses (1-2 injections) in each nostril 2-3 times a day.

When administered with a dosing device 1, a dose of 0.05% nasal gel contains 50 μg xylometazoline.

Galazolin in the form of nasal gel 0.1% is administered by administering to adults and children over 12 years of age 1 dose (1 introduction) to each nostril 2-3 times a day.

When administered with a dosing device 1, a 0.1% nasal gel dose contains 100 μg of xylometazoline.

Before applying the nasal gel each time, remove the nozzle, then press the dispenser 3-5 times until the appearance of the drug.

Do not use the drug in the form of a nasal gel or drops more than 3 times a day. The course of treatment is no more than 3-5 days. The maximum duration of application is 2 weeks, otherwise tachyphylaxis (addictive) or iatrogenic rhinitis may develop.

Side effect

• irritation and / or dryness of the nasopharynx mucosa;
• burning and paresthesia of the mucous membrane of the nasal cavity;
• sneeze;
• hypersecretion of the mucous membrane of the nasal cavity;
• edema of the nasal mucosa;
• palpitation;
• tachycardia;
• arrhythmia;
• increased blood pressure;
• headache;
• vomiting;
• insomnia;
• impaired vision;
• depression.

Contraindications

• atrophic rhinitis;
• angle-closure glaucoma;
• arterial hypertension;
• severe atherosclerosis;
• tachycardia;
• hyperthyroidism;
• surgical interventions on the meninges (in the anamnesis);
• simultaneous administration of MAO inhibitors and a period of 14 days after the end of their use;
• pregnancy;
• Children under 6 years of age (for 0.1% of nasal drops) and up to 2 years (for 0.05% of nasal drops);
• Children under 12 years of age (for 0.1% of nasal gel) and up to 3 years (for 0.05% of nasal gel);
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

The drug should be used only after assessing the risk-benefit ratio for the fetus and the mother.

Do not exceed recommended doses during pregnancy and lactation (breastfeeding).

Use in children

Contraindications: children under 6 years of age (for 0.1% of nasal drops) and up to 2 years (for 0.05% of nasal drops); Children under 12 years of age (for 0.1% of nasal gel) and up to 3 years (for 0.05% of nasal gel).

special instructions

Before application, it is necessary to clean the nasal passages.

Do not use the drug in patients with chronic or vasomotor rhinitis, as they tend to use the drug for more than 2 weeks.

Prolonged use of the drug (more than 2 weeks) can lead to a secondary expansion of the blood vessels and subsequently to iatrogenic rhinitis. The cause of this disease is the inhibition of norepinephrine release from the nerve endings by excitation of presynaptic alpha 2 receptors.

Impact on the ability to drive vehicles and manage mechanisms

Does not affect the ability to drive vehicles and service moving machinery.

Drug Interactions

With the simultaneous use of galazoline (with overdose or accidental ingestion) with tricyclic antidepressants or MAO inhibitors (including and before the application of xylometazoline), there is an increase in blood pressure.

Analogues of the drug Galazoline

Structural analogs for the active substance:

• Briisolin;
• Grippostad Rino;
• Fornos;
• Dr. Thyss Nazolin;
• Dr. Theiss Rinotheyss;
• Star;
• Influrin;
• Xylen;
• Xilobene;
• Xylometazoline;
• Ximelin;
• Ximelin Eco with menthol;
• Nosoline;
• Nosoline balm;
• Olint;
• Otrivin;
• Rhinomaris;
• Rinonorm;
• Rhinorus;
• Rhinostop;
• Sanorin Xylo;
• Sialer;
• Snoop;
• Suprema;
• Tizin Xylo;
• Tizin Xylo Bio;
• Pharmazoline;
• Eucazoline Aqua;
• Espazolin.

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