Odeston - instructions for use, reviews, analogs and dosage forms (tablets 200 mg) of choleretic medication for the treatment of cholecystitis, cholangitis, conditions after removal of the gallbladder in adults, children and pregnancy
In this article, you can read the instructions for using the drug Odeston. There are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists in the use of Odeston in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Odeston in the presence of existing structural analogues.Use to treat cholecystitis, cholangitis, conditions after removal of the gallbladder in adults, children, as well as during pregnancy and lactation.
Odeston - Cholagogue preparation. Increases the formation and secretion of bile. Has a selective antispasmodic effect on the bile duct and sphincter of Oddi. The drug does not reduce the peristalsis of the gastrointestinal tract and blood pressure.
Reduces stagnation of bile, prevents the crystallization of cholesterol and thus the development of cholestasis.
Composition
Gimecromone + auxiliary substances.
Pharmacokinetics
After oral administration, it is rapidly absorbed from the digestive tract. Poorly binds to plasma proteins. It is excreted in urine: about 93% in the form of glucuronate, 1.4% - in the form of sulfonate, 0.3% - unchanged.
Indications
- dyskinesia of bile ducts and sphincter of Oddi in hyperkinetic type;
- non-calculous chronic cholecystitis, cholangitis, cholelithiasis;
- condition after surgery on the gallbladder and biliary tract;
- a decrease in appetite, nausea, constipation, vomiting (on the background of hypoxecretion of bile).
Forms of release
Tablets 200 mg.
Instructions for use and dosage
The drug is prescribed inside for 30 minutes before meals.
Adults appoint 200-400 mg 3 times a day. The daily dose is 1200 mg.The course of treatment is 2 weeks.
Side effect
- diarrhea;
- flatulence;
- abdominal pain;
- Ulceration of the mucosa of the gastrointestinal tract (ulceration);
- allergic reactions;
- headache.
Contraindications
- obstruction of the bile ducts;
- kidney failure;
- liver failure;
- ulcerative colitis;
- Crohn's disease;
- peptic ulcer of the stomach and duodenum;
- hemophilia;
- children's age till 18 years;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
There is no data on the safety of gemecromone during pregnancy and lactation.
The appointment of Odeston during pregnancy and lactation (breastfeeding) is only permissible if the intended benefit to the mother exceeds the potential risk to the fetus or child.
Use in children
Contraindicated in children and adolescents under the age of 18 years.
special instructions
Does not impair the secretory function of the digestive glands and intestinal absorption processes.
Impact on the ability to drive vehicles and manage mechanisms
The drug does not affect the ability to drive vehicles and engage in other potentially hazardous activities,requiring increased concentration of attention and speed of psychomotor reactions.
Drug Interactions
With the simultaneous use of morphine, which causes spasm of the sphincter of Oddi, weakens the effect of Odeston.
With the simultaneous use of Odeston and metoclopramide, there is a mutual weakening of the effect.
Odeston enhances the effects of indirect anticoagulants.
Analogues of the drug Odeston
Odeston does not have structural analogs for the active substance.
Analogues on the pharmacological group (choleretic preparations):
- Allochol;
- Altalex;
- Berberis Homaccord;
- Berberis plus;
- Betaine citrate;
- Vitanorm;
- Gepabene;
- Hepatofalk the plant;
- Demidov elixir;
- Gastrointestinal collection;
- Cholagogue collection;
- Covechol;
- Livedoksa;
- Oxaphenamide;
- Olymetine;
- Sibektan;
- Tanacecole;
- Travohal;
- Tyqveol;
- Urdoks;
- Urolesan N;
- Urso 100;
- Ursodez;
- Ursodeoxycholic acid;
- Ursodex;
- Ursuliv;
- Ursor;
- Ursosan;
- Ursofalk;
- Febihol;
- Phytogastrol;
- Phytohepatol;
- Flamin;
- Chagolol;
- Cholebil;
- Holemax;
- Holenzim;
- Holos;
- Holosas;
- Holudexan;
- Hofitol;
- Tsinarix;
- Exxhol.
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