Genferon - instructions for use, analogs, testimonials and release forms (candles 125 000, 500 000, 1 000 000 and spray for light form) drugs for the treatment of herpes, chlamydia and other infections in adults, children and pregnancy
In this article, you can read the instructions for using the drug Genferon. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Genferon in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Genferon in the presence of existing structural analogues. Use for the treatment of genital herpes, chlamydia, ureaplasmosis and other urological infections in adults, children, as well as during pregnancy and lactation.
Genferon - Combined drug, the effect of which is due to the components that make up its composition. Has a local and systemic immunomodulatory effect.
Interferon alfa-2 has antiviral, antimicrobial and immunomodulatory effects. Under the influence of Interferon alpha-2, the activity of natural killers, T-helpers, phagocytes, as well as the intensity of differentiation of B-lymphocytes, increases. Activation of leukocytes contained in all layers of the mucosa ensures their active participation in the elimination of primary pathological foci and the recovery of production of secretory immunoglobulin A.
Taurine has membrane and hepatoprotective, antioxidant and anti-inflammatory properties, enhances tissue regeneration.
Benzocaine is a local anesthetic. Reduces the permeability of cell membranes for sodium ions, displaces calcium ions from receptors located on the inner surface of the membrane, blocks the conduct of nerve impulses. Prevents the appearance of painful impulses in the endings of the sensory nerves and their conduction along nerve fibers.
Pharmacokinetics
In vaginal or rectal application, interferon alpha-2 is absorbed through the mucous membrane, enters the surrounding tissues, into the lymphatic system, providing systemic action. It also has a local effect due to partial fixation on the cells of the mucous membrane.
The decrease in the level of serum interferon 12 hours after the administration of the drug necessitates its repeated administration.
Indications
As part of complex therapy for infectious and inflammatory diseases of the urogenital tract:
- genital herpes;
- chlamydia;
- ureaplasmosis;
- mycoplasmosis;
- recurrent vaginal candidiasis;
- gardnerellez;
- trichomoniasis;
- papillomavirus infections;
- bacterial vaginosis;
- erosion of the cervix;
- cervicitis;
- vulvovaginitis;
- bartholinite;
- adnexitis;
- prostatitis;
- urethritis;
- balanitis;
- balanoposthitis.
Forms of release
Candles for vaginal or rectal use 250 000 ME, 500 000 ME, 1 000 000 ME.
Candles Genferon Light vaginal or rectal 125 000 ME.
Spray for nasal application of Genferon Light dosed with 50 thousand IU + 1 mg / dose.
Instructions for use and dosing regimen
In infectious and inflammatory diseases of the urogenital tract in women, the drug is administered intravaginally with 1 candle (250thousand or 500 thousand IU, depending on the severity of the disease) 2 times a day for 10 days. For chronic diseases, the drug is prescribed 3 times a week (every other day) for 1 candle for 1-3 months.
In infectious and inflammatory diseases of the urogenital tract in men, the drug is administered rectally for 1 suppository (500,000 to 1 million IU, depending on the severity of the disease) 2 times a day for 10 days.
At the first sign of the disease, Genferon Light spray is administered intranasally for 5 days at a single dose (one push on the dispenser) to each nasal passage 3 times a day (one dose of approximately 50,000 IU of interferon alfa-2b, daily should not exceed 500,000 IU).
When in contact with an acute respiratory viral infection and / or during supercooling, the drug is administered according to the indicated scheme 2 times a day for 5-7 days. If necessary, preventive courses are repeated.
Spray Instructions
1. Remove the protective cap.
2. Before using for the first time, press the dispenser several times until a thin jet appears.
3. When using, keep the bottle in an upright position.
4. To make the injection of the preparation with a single pressure on the dispenser in each nasal turn alternately.
5. After use, close the dispenser with a protective cap.
To avoid the spread of infection, individual use is recommended (each member of the family has his own package).
Side effect
- skin rash, itching (these phenomena are reversible and disappear after 72 hours after dose reduction or drug withdrawal);
- headache;
- leukopenia, thrombocytopenia;
- increased body temperature;
- increased sweating;
- fatigue;
- myalgia;
- loss of appetite;
- arthralgia (pain in the joints).
Contraindications
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
If it is necessary to use the drug in the 2nd and 3rd trimester of pregnancy, the prospective benefit for the mother and the potential risk for the fetus should be correlated.
special instructions
The drug should be administered with caution to patients with allergic and autoimmune diseases in the acute stage.
Drug Interactions
When combined with antibiotics and other antimicrobials used to treat urogenital infections, the effectiveness of Genferon increases.
When used simultaneously with Vitamins E and C, the action of interferon increases.
When combined with non-steroidal anti-inflammatory drugs and anticholinesterase drugs, the action of benzocaine is potentiated.
When combined, the atibacterial activity of sulfonamides decreases (due to the action of benzocaine).
Analogues of the drug Genferon
There are no structural analogs to the active substance of the drug Genferon. However, there is a whole class of similar drugs that have a different chemical structure of their composition:
- Altevir;
- Alfaron;
- Alfaferon;
- Wallferon;
- Grippferon;
- Interferal;
- Interferon alfa-2 human recombinant;
- Intron A;
- Inferon;
- Layfferon;
- Lokferon;
- Ophthalmoferon;
- Realdiron;
- Reaferon-EU.
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