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Metronidazole - instructions for use, analogs, reviews and release forms (tablets 250 mg, suppositories 100 mg and 500 mg, cream, gel and injection solution) of the drug for the treatment of infections in adults, children and pregnancy

Metronidazole - instructions for use, analogs, reviews and release forms (tablets 250 mg, suppositories 100 mg and 500 mg, cream, gel and injection solution) of the drug for the treatment of infections in adults, children and pregnancy

In this article, you can read the instructions for using the drug Metronidazole. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Metronidazole in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Metronidazole in the presence of existing structural analogues. Use to treat infectious diseases of the sexual and intestinal sphere in adults, children, as well as during pregnancy and breast-feeding.

 

Metronidazole - antiprotozoal and antimicrobial drug, a derivative of 5-nitroimidazole. The mechanism of action is the biochemical reduction of the 5-nitro group by intracellular transport proteins of anaerobic microorganisms and protozoa. The reduced 5-nitro group interacts with the DNA of a cell of microorganisms, inhibiting the synthesis of their nucleic acids, which leads to the death of bacteria.

 

Metronidazole is not sensitive to aerobic microorganisms and facultative anaerobes, but in the presence of mixed flora (aerobes and anaerobes) metronidazole acts synergistically with antibiotics effective against conventional aerobes.

 

Increases the sensitivity of tumors to radiation, causes sensitization to alcohol (disulfiram-like action), stimulates reparative processes.

 

Pharmacokinetics

 

Has a high penetrating ability, reaching bactericidal concentrations in most tissues and body fluids, including lungs, kidneys, liver, skin, cerebrospinal fluid, brain, bile, saliva, amniotic fluid, abscess cavities, vaginal secretion, seminal fluid, breast milk, penetrates through blood-brain and placental barrier. It is excreted by the kidneys 60-80% (20% unchanged), through the intestine - 6-15%.

 

Indications

  • protozoal infections: extraintestinal amoebiasis, including amoebic liver abscess, intestinal amoebiasis (amoebic dysentery), trichomoniasis, giardiasis, balantidiasis, cutaneous leishmaniasis, trichomonas vaginitis, trichomonas urethritis;
  • infections caused by Bacteroides spp. (including V. fragilis, V. distasonis, V. ovatus, V. thetaiotaomicron, V. vulgalus): infections of bones and joints, infection of the central nervous system (including meningitis, brain abscess), bacterial endocarditis, pneumonia , empyema and abscess of the lungs;
  • Infections caused by Bacteuroides species, including B. fragilis group, Clostridium, Peptococcus and Peptostrеptococcus species: peritoneal infection (peritonitis, liver abscess), pelvic infections (endometritis, endometriometritis, fallopian tube and ovarian abscess, vaginal vagina infections after surgical operations) , skin and soft tissue infections;
  • infections caused by species of Bacteroides, including the B. fragilis group and Clostridium species: sepsis;
  • pseudomembranous colitis (associated with the use of antibiotics);
  • gastritis or duodenal ulcer associated with Helicobacter pylori;
  • alcoholism;
  • prevention of postoperative complications (especially interference on the colon, near-rectal area, appendectomy, gynecological operations);
  • radiation therapy of patients with tumors - as a radiosensitizing agent, in cases,when tumor resistance is due to hypoxia in tumor cells.

 

Forms of release

 

Tablets 250 mg.

 

Vaginal Candles 500 mg and 100 mg.

 

Cream for external use 1%.

 

Gel for external use 1%.

 

Gel for vaginal application 1%.

 

Solution for infusions (injections) 0,5%.

 

Instructions for use and dosing regimen

 

Inside, during or after a meal, (or squeezed milk), without chewing.

 

When trichomoniasis - 250 mg twice a day for 10 days or 400 mg 2 times a day for 5-8 days. Women should additionally be prescribed Metronidazole in the form of vaginal suppositories or tablets. If necessary, you can repeat the course of treatment or increase the dose to 0.75-1 g per day. Between the courses should be a break in 3-4 weeks with the conduct of repeated control laboratory tests. An alternative scheme of therapy is the appointment of 2 g once to the patient and his sexual partner. Children 2-5 years - 250 mg per day; 5-10 years - 250-375 mg per day, over 10 years - 500 mg per day. The daily dose should be divided into 2 divided doses. The course of treatment is 10 days.

 

With giardiasis, 500 mg twice a day for 5-7 days. Children under 1 year - 125 mg per day, 2-4 years - 250 mg per day, 5-8 years - 375 mg per day, over 8 years - 500 mg per day (in 2 divided doses). The course of treatment is 5 days.

 

With giardiasis - 15 mg / kg per day in 3 divided doses for 5 days.

 

Adults: with asymptomatic amoebiasis (if a cyst is detected), the daily dose is 1-1.5 g (500 mg 2-3 times a day) for 5-7 days.

 

In chronic amoebiasis, the daily dose is 1.5 g in 3 divided doses for 5-10 days.

 

In acute amoebic dysentery - 2.25 g in 3 doses until the symptoms stop.

 

In liver abscess - the maximum daily dose - 2.5 g in 1 or 2-3 doses, for 3-5 days, in combination with antibiotics (tetracyclines) and other methods of therapy. Children 1-3 years - 1/4 of the adult dose, 3-7 years - 1/3 of the adult dose, 7-10 years - 1/2 dose of the adult.

 

When balantidase - 750 mg 3 times a day for 5-6 days.

 

With ulcerative stomatitis, adults are prescribed 500 mg twice a day for 3-5 days; children in this case, the drug is not shown.

 

With pseudomembranous colitis, 500 mg 3-4 times a day.

 

To eradicate Helicobacter pylory - 500 mg 3 times a day for 7 days (as part of combination therapy, for example, combination with Amoxicillin 2.25 g per day).

 

In the treatment of anaerobic infection, the maximum daily dose is 1.5-2 g.

 

In the treatment of chronic alcoholism, 500 mg per day for a period up to 6 (not more than) months are prescribed.

 

For the prevention of infectious complications - 750-1500 mg per day in 3 doses 3-4 days before surgery, or once 1 g in the 1-st day after the operation.1-2 days after the operation (when already allowed ingestion) - 750 mg per day for 7 days.

 

Ointment and gel

 

Assign intravaginally. The recommended dose is 5 g (one complete applicator) 2 times a day (morning and evening). The course of treatment is 5 days.

 

Side effect

  • diarrhea;
  • anorexia;
  • nausea, vomiting;
  • intestinal colic;
  • constipation;
  • metallic taste in the mouth;
  • dry mouth, glossitis;
  • stomatitis;
  • dizziness, impaired coordination of movements;
  • ataxia;
  • confusion of consciousness;
  • irritability;
  • depression;
  • increased excitability;
  • weakness;
  • insomnia;
  • headache;
  • convulsions;
  • hallucinations;
  • urticaria, skin rash;
  • hyperemia of the skin;
  • nasal congestion;
  • fever;
  • candidiasis;
  • neutropenia, leukopenia.

 

Contraindications

  • leukopenia (including in the anamnesis);
  • organic lesions of the central nervous system (including epilepsy);
  • hepatic failure (in the case of the appointment of large doses);
  • pregnancy (1 trimester);
  • lactation period;
  • hypersensitivity.

 

Application in pregnancy and lactation

 

Contraindicated in the 1st trimester of pregnancy and lactation. Use with caution in the 2nd and 3rd trimesters of pregnancy.

 

special instructions

 

During the treatment, the use of ethanol (alcohol) is contraindicated (it is possible to develop a disulfiram-like reaction: spastic abdominal pain, nausea, vomiting, headache, sudden rush of blood to the face).

 

In combination with amoxicillin it is not recommended to use in patients younger than 18 years.

 

With prolonged therapy, it is necessary to monitor the blood picture.

 

The appearance of ataxia, dizziness and any other deterioration in the neurological status of patients requires discontinuation of treatment.

 

Can immobilize treponema and lead to Nelson's false positive test.

 

Stains urine in a dark color.

 

When treating trichomonadal vaginitis in women and trichomoniasis in men, it is necessary to abstain from sexual activity. It is necessary to simultaneously treat sexual partners. Treatment does not stop during menstruation. After trichomoniasis therapy, control tests should be performed for three consecutive cycles before and after menstruation.

 

After the treatment of giardiasis, if symptoms persist, after 3 to 4 weeks, 3 feces should be analyzed at intervals of several days (in some successfully treated patients lactose intolerance caused by invasion may persist for several weeks or months, recalling the symptoms of giardiasis).

 

Drug Interactions

 

Increases the effect of indirect anticoagulants, which leads to an increase in the time of prothrombin formation.

 

Similarly to disulfiram, causes intolerance to ethanol (alcohol).

 

Simultaneous use with Disulfiram can lead to the development of various neurologic symptoms (the interval between appointments is at least 2 weeks).

 

Cimetidine inhibits metronidazole metabolism, which can lead to an increase in its serum concentration and an increased risk of side effects.

 

Simultaneous administration of drugs that stimulate enzymes of microsomal oxidation in the liver (phenobarbital, phenytoin) can accelerate the elimination of metronidazole, as a result of which its concentration in the plasma decreases.

 

With simultaneous administration with lithium preparations, the concentration of the latter in the plasma and the development of symptoms of intoxication may increase.

 

It is not recommended to combine with nondepolarizing muscle relaxants (vecuronium bromide).

 

Sulfonamides increase the antimicrobial effect of metronidazole.

 

Analogues of the drug Metronidazole

 

Structural analogs for the active substance:

  • Bacimex;
  • Deflamon;
  • Clion;
  • Metrovagin;
  • Metrogil;
  • Metroxan;
  • Metrolacker;
  • Metron;
  • Metronidazole Nycomed;
  • Metronidazole-AKOS;
  • Metronidazole-Altpharm;
  • Metronidazole-LekT;
  • Metronidazole-UBF;
  • Metronidal;
  • Metroseptol;
  • Orvagil;
  • Rosamet;
  • Rosex;
  • Siptrogyl;
  • Tricho-PIN;
  • Trichobrol;
  • Trichopol;
  • Trichosept;
  • Flagel;
  • Efloran.

Similar medicines:

Other medicines:

Reviews (73):
Guests
TomaT
I was treated with metronidazole for acne. Before the onset of menstruation, they poured out huge pimples, each time, and the pimples then merged into one huge bubble, which left behind huge red spots. And as soon as one bubble passed, another appeared immediately. Every menses was excruciated. As a result, bought Metronidazole in the pharmacy and after she drank all 20 tablets, the skin cleared and now even before the menstrual period and during the period of the skin is clean,I do not observe any acne. The truth is to appear to the doctor before the treatment, after all, the drug is strong.
Guests
Anton
Metronidazole was treated with colitis, associated with a prolonged intake of antibiotics (chronic infection). No complaints about the medicine I will not find, it was cheap, angry though long, but the disease is not ordinary, the main thing is to drink medicine as prescribed by a doctor, after all, an antibiotic.
Guests
Marina
I was prescribed a drop of Metronidazole - AKOSA in the hospital. I sustained only 2. I will begin with the fact that during the infusion the hand was terribly ill, all numb and cold to the touch. After the coordination of movements was disrupted, I could not focus my eyes on objects, I was stuck in walking, before my eyes everything "floated", nauseated, metallic taste in my mouth, depression right down to suicidal thoughts! In short, a full Trinde! I will never again agree to this "medicine".
Guests
Basil
After a 2-day drinking-bout, I drank 2 days with horse doses, this drug - I go like a plant .... If I was taking care of beer, it would be faster and more pleasant! )
Guests
Irina
They stabbed with an erosive gastritis. After a week, lactation began. I'm terrified! At the doctor I in practice such first. Canceled. On the third day passes. Well, metallic taste in the mouth all the time.
Administrators
admin
Irina, Galactorrhea is indeed a very rare side effect of taking Metronidazole. You can see this antibiotic does not suit you, given that there is also a metallic taste in your mouth.
Guests
olga
After taking metronidazole, she noticed that my pulse rate increased, I could not fall asleep until I drank Corvalol.
Guests
Tatyana.
To me have attributed at a genyantritis. In the instruction there is nothing about it. I take pills. It seems a little easier.
Guests
Lyudmila
Toxicosis after metronidazole. Nausea, wild intestinal colic, generally none, not workable. With that, I take metronidazole along with the lineage.
Visitors
Elena5031
I started taking yesterday from demodicosis according to the doctor's prescription, I drank only 2 tablets, today all the sweltering woke up, my face burns, a headache, a metallic taste in my mouth and cystitis began. I'm afraid to continue taking this drug. And now what i can do? Than it is possible to replace?
Administrators
admin
Elena5031, It is necessary to cancel, since there are obvious signs of adverse reactions, and numerous, so treatment has not gone and this is not your drug. Perhaps, it is worthwhile once again to see a doctor, since with demodicosis did not come across and the effective treatment tested by experience will not prompt, but Metronidazole with this diagnosis is really a good drug.
Guests
Galina
I was given candles Flagil for 467 r, when I read that it was metronidazole, I was upset, I even went to the doctor to understand why she writes such unemployed workers. As a result, the doctor assured me that the usual metronidazole is harder to cure, since it is hard and goes all out. Is she right?
Administrators
admin
Galina, The active ingredient in the drugs is the same - metronidazole, various auxiliary substances: Flagil is a solid fat, Metronidazole in candles has a macrogol. Your doctor, of course, knows better, because he is responsible for the result, but I write out my medicine for my patients to my patients. Can he buy a good imported - let him buy, can not - better write domestic, so that at least he bought and healed, than he abandoned the matter altogether. Sometimes our help is not worse.
Guests
Nina Viktorovna
Have a nice day! I was tortured with my ears: from the cervical chondrosis the hearing decreased. Now I'm swept off the drugs with ototoxic properties. Please, tell me, are good people, metronidazole or trichopolum affected negatively by hearing ?! I am immensely grateful for your reply!
Administrators
admin
Nina Viktorovna, Injectable form of metronidazole (in injections) can lead to hearing loss (such side effect is present in the instructions for use). The tablet form of the preparation does not contain such a side effect.
Visitors
nadia
Hello, how often can I take metronidazole? Taken in the treatment of postinfection colitis in the hospital. Now the condition has worsened, the pediatrician and the doctor from the hospital say the child checked everything in the statement is, the child is 16 years old, last drank metronidazole a month ago with a course of 5 days.
Administrators
admin
nadia, Metronidazole can be taken for a long time, if there is a need, which should be determined by the attending physician, in your case, the pediatrician. About the statement did not understand. If any recommendations were given in the discharge from the hospital, they are also required to perform, especially with such a complex diagnosis as colitis.
Guests
my mother
my mother, Moved your question to the drug Flagil, where it is more appropriate.
admin
Visitors
FantamasOFF
I'm lying with a broken jaw and metronidazole is being injected through the system. For what? It will be interesting to know.
Administrators
admin
FantamasOFF, Probably for the prevention of infectious complications and gangrene, especially if the skin was damaged. Perhaps there were other reasons. I propose to ask you about this from your doctor.
Visitors
Vitara
The drug was prescribed together with ciprofloxacin after removal of the uterine polyp. As I understand it, as prevention of complications. I drink the second day and immediately after taking terrible pain in the stomach, literally on the wall creep, nauseated, dizzy. Should I still continue to take these drugs with such pills or quit? Take 5 more days, but I think I can not stand it.
Administrators
admin
Vitara, See a doctor who has given you Metronidazole after surgery to prevent infectious complications. Antibiotics now let a lot choose the one that is right for you. I do not advise you to throw the medication yourself, it is possible to develop infectious complications, and this is completely different antibiotics will be used or surgical treatment.
Visitors
oksana 74
Hello. Diagnosis of bacterial vaginosis. How many days is enough to take this drug?
Administrators
admin
oksana 74, On average 5 to 8 days of taking Metronidazole in tablets or vaginal suppositories will be enough. However, a more precise time frame for your case and the dosage form of admission will tell you the gynecologist to whom you need to apply for a prescription.
Guests
Alyona
Saw by appointment of the doctor, these pills, on the first day, began a terrible pain in the lower abdomen, made an enema, sort of let go. On the second day by the evening I was so shaken, vomiting began, all the night I turned inside out, I thought I would lose consciousness ... It was all over in the morning, when they injected the cerucal. I do not take the second day, but I still feel sick. I am now afraid. Over night 2 kg was gone. Here such I had consequences.
Guests
Irina
Appointed after curettage + suppositories ruferon.
Visitors
Obloka5320
Hello. Lamiter was prescribed and to enhance the effect of metronidazole (1 ton per day) from mycosis of the feet (fungal nail fungus), but nothing is indicated in the instruction on the antifungal effect of metronidazole. Maybe something is not right?
Administrators
admin
Obloka5320The combination is correct. Metronidazole refers to the azole group of drugs, which includes such antimycotic (antifungal) drugs as Itraconazole, Fluconazole, Clotrimazole and others. And the drug Lamiter contains Terbinafine, which refers to allylamines and this group of drugs also fights well with the fungus. As a result, both components of your treatment mutually potentiate the antifungal effect and, in the case of a fungal run, the feet will be more effective. There are also many antifungal drugs based on combinations with Metronidazole - Vagiferon, Clomegel, Neo Metronikon, Neo Penotran and many others.
Visitors
Obloka5320
Thanks for the answer.
Visitors
elena 555
Metronidazole with helicobacter pylori is effective.
Administrators
admin
elena 555If this was a question, then yes, Metronidazole is used in eradication schemes for Helicobacter pylori treatment. But since according to recent studies in our latitudes the effectiveness of using Metronidazole in Helicobacter therapy is 50%, in the triple regimens of treatment (for example, the proton pump inhibitor (Omeprazole) + Amoxicillin + Metronidazole) this antibiotic is not used. But in schemes with four drugs - use, but primarily usually Metronidazole is not prescribed, since the first line of therapy is a triple scheme of eradication.
Visitors
hzitywtdf73
The throat hurts already three weeks, has spent on drink amoxicillinum, constantly I rinse with a camomile, I splash hexosphere, everyones lollipops from a throat, honey with a lemon, nothing helps or assists. Now have appointed metronidazole, in the instruction on application nothing is told or said, about a sick throat ... How to be?
Administrators
admin
hzitywtdf73If more than 3 or more than 4 weeks have passed since the antibiotic treatment, I would have given smears from the pharynx to the flora and sensitivity to antibiotics. And then the antibiotic alone and the effect is gone, why the second time to be treated with your finger in the sky, when you can find out which bacterium (and possibly the fungal infection) causes soreness and is already aiming to deal with it. And can there already a tonsillitis in a stage of a decompensation and it is necessary to delete tonsils. So address to responsible LORu that has looked or seen you and has directed where it is necessary.
Guests
Elena78
Elena78, Postponed your question-feedback to the drug Metrogil, where it is more appropriate.
admin
Visitors
Oksana_
Good afternoon! 3 days the temperature reached 39, it was bad. Analyzes showed ESR 56, white blood cells 15.2, lungs clean, no pneumonia, no signs of SARS, throat, nose all right. Only general weakness is felt, bones ache and all. At the moment, the temperature is 37. The doctor prescribed the antibiotic Unidox and Metronidazole. Prompt at this point it makes sense to take metronidazole or we need to do some other examinations? I would be grateful for the recommendations!
Administrators
admin
Oksana_, Total blood is done, you can make a general urine to exclude inflammation in the urinary tract, a lung X-ray and a consultation of the gynecologist is shown - if the patient is a woman. Inflammation of some kind is present, but here so immediately without a clear focus to treat - I do not. The reason is paramount.
Visitors
Eva55
Hello. From gardnerelly the doctor prescribed metronidazole 2 tablets (500 mg) 2 times a day for 7 days and clindacin. Is the treatment correct and will there be an overdose?
Visitors
suntsvetlana
I am treating periodontitis of teeth. The doctor prescribed metronidazole 2 tablets 2 r / day. I'm allergic to antibiotics and the allergist said no more to provoke the body with antibiotics, tk. there was a swelling of the Quincke. Can I drink this medicine or can I substitute something (if possible with something natural)?
Administrators
admin
Eva55When determining the pathogen according to the correct one, the sensitivity of the seeded to antibiotics should be determined. Having an antibioticogram in my hands, I could tell you clearly whether the treatment was prescribed correctly.And we like to determine the cause and to treat a finger in the sky, based on our own experience, so the treatment schemes for the same diseases will differ for different doctors.

Gardnerella is difficult to cure, to say for sure whether you will be enough for a prescribed complex of drugs is difficult. Try, you still do not have any alternatives or you look for a doctor who heals by science and sends you for retake of tests if you have not yet begun taking antibiotics.

suntsvetlanaHaving a history of Quincke's edema, of course, one should be extremely cautious with any antimicrobial drugs and start taking them in medical institutions where emergency medical care can be provided. Metronidazole in this regard can not be an exception.

I am not a dentist, therefore, for the treatment of periodontal disease, you should contact a specialist from whom you were, so that he corrects the treatment regimen that will help your problem and not cause unnecessary allergic reactions.
Guests
Zavadskaya Ali
A terrible drug! I vomited from him, I felt sick for 2 days, my head was spinning, my stomach ached. And the whole face was covered with pimples.And I found confirmation that it was all because of him. This is what he has in his hand. I do not advise in any way!
Guests
olga
Hello, but this medicine suits me, there are no side effects. I treated my throat, and before that on gynecology.
Guests
Tatyana
With a cyst on the kidney, can I take this medication?
Administrators
admin
Tatyana, Kista on the kidney is not a contraindication limiting the intake of the drug Metronidazole. If the question was whether such an appointment is necessary - this is already for your treating doctor, he decides the origin and tactics of cyst treatment.
Guests
Galymzhan
Hello. I have a diagnosis of giardiasis. A terrible stink of gold of the mouth, can this be related to this? All teeth are normal. In the program Elena Malysheva recommend this particular medicine. Tell me whether it helps 100%?
Administrators
admin
Galymzhan, Metronidazole is used to treat giardiasis.A detailed scheme of therapy and the reasonableness of the appointment of this particular drug will be prompted by a doctor, to whom you need to address internally.
Visitors
cobra
Hello! The doctor diagnosed thrombophlebitis and prescribed Metronidazole and Xarelto. The latter in the instructions indicated "Xarelto is not recommended for use in patients receiving systemic treatment with antifungal agents of the azole group." Does this mean that Metronidazole and Xarelto are incompatible?
Administrators
admin
cobra, Does not mean. Metronidazole does not belong to the antifungal drugs of the azole group. This group includes the antimycotics ketoconazole, clotrimazole, miconazole, bifonazole, fluconazole and others.
Visitors
suvalova.yu
Have appointed or nominated metronidazolum 0,5 3 times a day from an inflammation in gynecology. Already on day 2, I felt sick and dizzy. Should I reduce the dose?
Administrators
admin
suvalova.yuIf side effects are significant and interfere with normal daily activities, it is best to consult a doctor who has appointed Metronidazole to cancel the drug or replace it with another medicine. From the reduction of dosage will be only harm, because pobochka can not go away, and treatment in this case will not give the proper effect.
Guests
Selena1111
Tell me if there will be an overdose of the drug with the tank. Vaginosis use candles twice a day and take a pill morning and evening? Or one of this is enough?
Administrators
admin
Selena1111, Ask your doctor, I do not comment on self-treatment. Maybe these schemes are prescribed to you by an expert - then change the doctor to an adequate one.
Guests
Irina
Does demodicosis help? The instructions do not say anything about demodex.
Administrators
admin
Irina, Dermatologists appoint Metronidazole from demodex mites. They say it helps.
Guests
Ruzanna
Hello.I'm already 5-th day as I drink metronidazole. The doctor on gynecology has appointed or nominated, but at me the toxicosis has begun: the head turns round, nervousness, delicacy awful, but for me it is tolerant. After treatment, will there be side effects?
Administrators
admin
RuzannaIf side effects are caused by taking Metronidazole, then most likely they will pass after the end of the course of treatment. If these negative symptoms are caused by other causes or are a consequence of the disease itself (which is not indicated in the question), it is unlikely.
Hello, dear admin!
Tell me, please, metronidazole is used intravenously with a preliminary diagnosis of cholecystitis? The question is not about self-medication. The patient is of age.

I also want to ask what to do. To the father after systems with this preparation flocks of birds flock in the ward and outside the windows. To say this to the doctors is terrible, they will find it, it is clear for whom. I put a normal person in the hospital. Droppers with metronidazole are diagnosed with gallstones and acute cholecystitis.

Dear admin, help, please. Unfortunately, my worst fears were justified. Arriving today to my father in the ward, I found out that he would not recognize me, after another intravenous infusion of the metronidazole vial. After he received another bottle of this infernal drug with me, he began to confuse the windows of the room with the doors, and the ceiling of the room with the table, which he told me. I'm in such a shock that I do not know what to do and I can not sleep right now. Dad gets metronidazole and injections of some antispasmodic and antibiotic in the preliminary, without ultrasound and analysis, the diagnosis of gallstones and cholecystitis. The diagnosis was based on the image of the uzi apparatus. On uzi the doctor on uzi-diagnostics, as she said, has noticed, that at it or him are completely filled in with stones by ducts of cholic. He is also being given, as I was told, an "infusion" with intravenous sodium chloride and glucose injections to remove intoxication and remove the toxins. On my hands, I have analyzes a month ago, on which both the bilirubin of blood is normal, and there are not any ocas that should be with inflammation and gallstones. I do not know if I can hope for your help, but my email address is ***** (please do not show it and this message is here on the site).
Tell me, is it true that metronidazole is contraindicated in patients with polyneuropathy? The father has symptoms: tingling in the skin, a feeling of dryness and roughness of the hands, a tied gait, difficulties in holding things in hands, feeling numbness in the limbs.
Administrators
admin
Natalia 08042015, I do not consult by mail, only within the site and only to registered visitors. On your question - the first thing to do is to calm you down. The second is to tell about the patient having side effects in the form of mental disorders to the doctor. What they think is their problems, the main thing is for them to understand that before the admission the patient was adequate, but now it is not. If the patient is an age-old, it is quite possible that the blood circulation of the brain is by itself, and cholecystitis and the drugs used separately. Here it is necessary to understand everything that happens to be reported to the attending physician. If everything is as you describe, perhaps the appointment of antibiotics is justified, because if you do not fight with inflammation, plus stones, stasis of the bile ducts can develop, jaundice will go and an urgent operation will be needed.So from the available doctors usually choose the best, but when the psychiatric symptomatology after the treatment goes, the problem is either not connected (other organs and systems are involved), or intoxication, or a side effect from the drugs being administered. It's not a fact yet that Metronidazole is to blame, because, judging by the question, you do not know the full spectrum of the treatment you are taking. Blood tests of a month ago are not indicative, if the condition is urgent, then the blood can react swiftly, so if there is an ultrasound of the liver and ducts of a month ago and there are no stones, then it would be extremely strange.

Natalia 08042015, Not true. Metronidazole may cause symptoms of peripheral polyneuropathy, but this is not a contraindication to admission. Naturally, any doctor when prescribing a drug looks at the accompanying diseases and conditions of the patient and tries to prescribe a medicine that will help in the treatment of the underlying disease and does not provoke exacerbations of the attendant, but not always it is possible, then the question of choice in life priorities and medical experience.
Visitors
Vlada
Hello! I accept Metronidazole Nycomed in the scheme of the second line of eradication Helikobakter. The doctor prescribed 10-14 days. Is it enough 10 days or better still 14? I would not want to finish the liver (there was chronic hepatitis). And can you advise an antifungal agent? In the scheme there is also tetracycline. Always after antibiotics thrush begins.
Administrators
admin
VladaIf the first time you spend eradikatsii helikobakter enough and 10 days of taking Metronidazole and other drugs according to the scheme. After you can poprinimat with another month Omeprazole or Omez, if there are negative symptoms from the gastrointestinal tract associated with gastritis, ulcer, GERD.

Of antibacterial drugs, I prefer Diflucan, but it's expensive. Any fluconazole and its commercial counterparts can be used cheaper.
Dear admin, I am grateful and grateful to you for your time and so detailed answers.You with a holiday of worthy people - on February, 23rd!
Visitors
Vlada
The first eradication was unsuccessful (Razo, Flemoksin, Vilprafen, De-Nol) 14 days.
This is the second line (I indicated). Then all the same 14 days?
Omeprazole is somewhat better than other PPIs?
Thank you.
Administrators
admin
Vlada, Then it is better to take all 14 days. Of proton pump inhibitors (PPIs), I prefer Pantoprazole and its commercial counterparts (Nolpaza, Sanpraz and others), as well as Esomeprazole and its commercial counterparts (Emanera, Nexium and others).
Is it necessary after taking the metronidazole systems received by the patient with gall bladder stones and cholecystitis, to take drugs that restore the intestinal microflora (linex)? There is a B12 deficiency and the question of the state of the intestinal microflora.

Tell me, please, whether metronidazole administration has limitations on such grounds as:
-About 70 years of age,
Cardiovascular diagnoses (hypertension, angina pectoris, aortic stenosis, anemia with B12 deficiency),
-symptoms of polyneuropathy,
-increased number of leukocytes (4.3).

Thank you very much in advance.
Administrators
admin
Natalia 08042015, On the first question. Restore anything is necessary only if the intestinal dysbiosis is really disturbed, there are stool disorders, nausea, which continue for 3 days after the end of antibiotic intake. In the rest it is possible to do with the use of sour-milk products (kefir, yogurt and others), this is enough to restore a slight violation of microbial balance in the intestine.

On the second question. I remember that your age patient Metronidazole was prescribed for cholecystitis. In this case, for one cup of weights, we add the patient's burden from the new sore, the dynamics of the development of the disease, to the other - all that you listed in the question. Sometimes you have to take a reasonable risk and give even antibiotics forbidden to a particular patient if a significant deterioration or possible death is expected. Here you can already sort out only in person, watching the patient.
According to the instructions, metronidazole is able to cause polyneuropathy. What does he do with nerve cells, what kind of damaging effect does this drug have on them? I would at least understand what happened to my father.

Before metronidazole, he had polyneuropathic symptoms, which the CRH doctors did not want to see, as well as the fact that he had a B12 deficiency. With the beginning of the course of metronidazole, polyneuropathy became sharply aggravated.

After replenishing the level of vitamin B12 in the blood (from the initial 30 pg / ml to the current 394), neurologic manifestations were not completely removed, poorly owned hands. The neurologist gives treatment for alcoholic polyneuropathy, which has nothing to do with our case.
Administrators
admin
Natalia 08042015, The concrete mechanism of the destructive effects of Metronidazole on the nervous system in the case of your father will not prompt, I do not know this mechanism. Probably, the toxic effect of the medicine, which has stratified on already begun manifestations of neuropathy, plus age. In terms of alcohol and non-alcoholic neuropathy treatment will be the same,so I would have used a better term such as toxic neuropathy, and already with what poison (alcohol or other toxin) nerve fibers were damaged for treatment is not particularly important.
Guests
Olga
I drink metronidazole as prescribed by the doctor for 7 days. I transfer the drug tolerantly, from pobochek: sour taste, depression and insomnia, sometimes faster pulse. Remained 3 days, but yesterday, in addition to the above pobochek, a panic attack occurred. I used to know how to fight it with a bubble of Corvalol. And what about now, in the composition of corvalol ethanol which is strictly contraindicated in the administration of metronidazole. How to be, what sedatives can I take?
Administrators
admin
Olga, All true alcohol with Metronidazole to accept categorically it is impossible, it causes reactions of a poisoning (spasmodic pains in a stomach, a nausea, vomiting, a headache, a sudden rush of blood to the person).

If a panic attack is provoked by an organic disease of the nervous system, it is better to consult a doctor who will tell you the necessary medications.If everything is as described, then probably you can only focus on the methods of auto-training without the use of medication or help taking Phenobarbital (this substance is contained in Corvalol and determines its sedative or soothing effect). And if the attack was provoked by taking Metronidazole and is not associated with an organic disease, in this case, the use of suppressive drugs will be useless and will help only the withdrawal of the drug. In any case, consult a doctor in person.
Visitors
alexander88
alexander88, Moved your question to the drug Metrogil, where it is more appropriate.
admin
Visitors
kristina66
Tell me, how much can I re-smear the flora after taking metronidazole?
Administrators
admin
kristina66A second smear for the definition of sexually transmitted infections (STIs) is acceptable after 3 weeks after taking antibiotics. I advise my patients to do this in a month, for reliability.
Guests
Olga
It is best to drink Trichopolum.

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