Sextapage - instructions for use, analogs, reviews and release forms (liquid polyvalent solution for external use) of the bacteriophage drug for the treatment of purulent infections in adults, children and in pregnancy
In this article, you can read the instructions for using the drug Sextapage. There are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists in the use of the bacteriophage Sextafag in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Sextapage in the presence of existing structural analogues.Use to treat purulent infections and treatment of wounds in adults, children, as well as during pregnancy and lactation.
Sextapage - has the ability to specifically lyse microorganisms (staphylococci, streptococci, pathogenic intestinal and pseudomonas aeruginosa), Proteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae.
Composition
Mixture of phagolysate of staphylococci, streptococci, Escherichia coli, Proteus, Pseudomonas aeruginosa and Klebsiella pneumonia (Piobacteriophage polyvalent) + Auxiliaries.
Indications
Prevention and treatment of various forms of diseases and conditions caused by the above pathogens:
- purulent-inflammatory diseases of the ear, throat, nose, respiratory tract, lungs and pleura (inflammation of the sinuses of the nose, middle ear, sore throat, pharyngitis, laryngitis, tracheitis, bronchitis, pneumonia, pleurisy);
- surgical infections (purulent skin lesions, suppuration of wounds, abscess, phlegmon, mastitis, osteomyelitis, peritonitis, burns);
- urogenital infection (urethritis, cystitis, pyelonephritis, colpitis, endometritis, salpingoophoritis);
- enteral infections (gastroenterocolitis, cholecystitis, intestinal dysbacteriosis);
- generalized septic states;
- purulent-septic diseases in newborns and infants (omphalitis, pemphigus, gastroenterocolitis, sepsis);
- treatment of freshly infected wounds;
- prevention of nosocomial infections due to epidemiological indications.
Forms of release
Solution for oral, topical and topical use (liquid polyvalent) 20 ml.
Instructions for use and how to use them
Before use, the bacteriophage vial must be shaken and scanned. The drug should be clear and free of sediment.
Attention! In case of turbidity, do not use the drug!
Due to the content of the nutrient medium in which the bacteria can develop from the environment, causing the drug to cloud, it is necessary to observe the following rules when opening the vial:
- Wash hands thoroughly;
- treat the cap with an alcohol-containing solution;
- remove the cap without opening the plug;
- Do not put the stopper on the inside of the table or other objects;
- do not leave the vial open;
- The opened vial should be stored only in the refrigerator.
When using small doses (2-8 drops), the drug should be taken with a sterile syringe in a volume of 0.5-1 ml.
The preparation from the opened bottle under observance of storage conditions, the above rules and absence of turbidity can be used during the whole shelf life.
Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both topically and by taking the drug inside within 7-20 days (according to clinical indications).
Depending on the nature of the source of infection, the bacteriophage is used:
1. Locally in the form of irrigation, lotion and tamponization with liquid phage in an amount up to 200 ml, depending on the size of the affected area. When abscesses, the bacteriophage is injected into the cavity of the focus after removal of the pus by puncture. The amount of the drug administered should be somewhat less than the volume of the removed pus. When osteomyelitis after appropriate surgical treatment, a bacteriophage 10-20 ml is poured into the wound.
2.Introduction into cavity - pleural, articular and other limited cavities up to 100 ml of bacteriophage, after which capillary drainage is left, through which bacteriophage is repeatedly introduced for several days.
3. For cystitis, pyelonephritis, urethritis, the drug is taken orally.In case the cavity of the bladder or renal pelvis is drained, the bacteriophage is injected through the cystostomy or nephrostomy 1-2 times a day for 20-50 ml in the bladder and 5-7 ml in the renal pelvis.
4. With purulent-inflammatory gynecological diseases, the drug is injected into the cavity of the vagina, the uterus in a dose of 5-10 ml daily once.
5. With purulent-inflammatory diseases of the ear, throat, nose, the drug is administered in a dose of 2-10 ml 1-3 times a day. Bacteriophage is used to rinse, rinse, instill, inject wetted turund (leaving them for 1 hour).
6. With conjunctivitis and keratoconjunctivitis, the drug is injected 2-3 drops 4-5 times a day, with a purulent ulcer of the cornea - 4-5 drops, with purulent iridocyclitis, the drug is used 6-8 drops every 3 hours in combination with oral intake.
7. In the treatment of stomatitis and chronic generalized periodontitis, the drug is used in the form of mouth rinses 3-4 times a day at a dose of 10-20 ml, as well as by insertion into the periodontal pockets of turunds soaked with iobacteriophage for 5-10 minutes.
8. When intestinal forms of the disease, diseases of internal organs, dysbacteriosis bacteriophage is used through the mouth and in the form of enemas for 7-20 days.Through the mouth, the bacteriophage is given 3 times a day on an empty stomach 1 hour before meals. In the form of enemas prescribed 1 time per day instead of one reception through the mouth.
In the event that chemical antiseptics were used before the bacteriophage was used to treat wounds, the wound should be thoroughly washed with a sterile 0.9% solution of sodium chloride.
Use of bacteriophage in children (up to 6 months)
In sepsis, enterocolitis of newborns, including premature babies, the bacteriophage is used in the form of high enemas (through the gas pipe or catheter) 2-3 times a day. In the absence of vomiting and regurgitation, the use of the drug through the mouth is possible. In this case, it is mixed with breast milk. Perhaps a combination of rectal (in enemas) and oral (through the mouth) application of the drug. The course of treatment is 5-15 days. With a recurring course of the disease, repeated courses of treatment are possible. In order to prevent sepsis and enterocolitis with intrauterine infection or the danger of nosocomial infection in newborns, the bacteriophage is used as an enema 2 times a day for 5-7 days.
In the treatment of omphalitis, pyoderma, infectedwounds the drug is applied in the form of applications daily twice (the gauze wipe is moistened with a bacteriophage and applied to the umbilical wound or to the affected area of the skin).
Side effect
There have been no reactions to the administration of Sextapage.
Contraindications
- individual intolerance of the drug.
Application in pregnancy and lactation
It is advisable to use the drug during pregnancy and during breastfeeding in the presence of infections caused by phagosensitive strains of bacteria (on the recommendation of a doctor).
Use in children
It is possible to use the drug in children according to age-related dosages.
special instructions
Opening of vials and ampoules, the procedure for the introduction of a polyquatic Sextapage is carried out with strict adherence to the rules of antiseptics. Before use, the vials and ampoules are shaken and scanned - the preparation should be clear and free of sediment. If the drug is clouded or the integrity of the package is not affected, it is not used. Storage of the drug after opening the vial or ampoule is not allowed.
Drug Interactions
The use of Sextapage does not exclude the use of other antibacterial and anti-inflammatory drugs.
Analogues of the drug Sextapage
Structural analogs for the active substance:
- Piobacteriophage complex liquid;
- Piobacteriophage polyvalent purified;
- Piopolyphage;
- Sextapage (Piobacteriophage polyvalent liquid).
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