Betaserk - instructions for use, analogs, reviews and release forms (tablets 8 mg, 16 mg, 24 mg) of the drug for the treatment of Ménière syndrome and dizziness in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Betaserc. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Betaserka in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Betaserk with available structural analogues. Use to treat Meniere's syndrome, dizziness and tinnitus in adults, children, as well as during pregnancy and lactation.Composition of the preparation.

Betaserc - a synthetic analog of histamine. The agonist of histamine H1 receptors of the inner ear vessels and the antagonist of histamine H3 receptors of the vestibular CNS nuclei. According to preclinical studies, by relaxing the pre-capillary sphincters of the inner ear vessels, it improves blood circulation in the vascular space of the inner ear.

It dose-dependently reduces the generation of action potentials in the neurons of the lateral and medial vestibular nuclei. Accelerates the recovery of the vestibular function after unilateral vestibular neurectomy, speeding up and facilitating central vestibular compensation (due to antagonism with histamine H3 receptors). It alleviates symptoms in Meniere's syndrome and vertigo.

Composition

Betahistine dihydrochloride + excipients.

Pharmacokinetics

When ingesting Betaserk quickly and almost completely absorbed from the digestive tract. After absorption, the drug is quickly and almost completely metabolized to form an inactive metabolite of 2-pyridylacetic acid. The excretion of Betagistin by the kidneys or through the intestine is negligible. When taking the drug with food, the maximum concentration of the drug in the blood is lower than when taken on an empty stomach.However, the total absorption of betahistin is the same in both cases, indicating that eating only slows the absorption of betahistine.

Indications

Meniere's syndrome, characterized by the following main symptoms:

• dizziness (accompanied by nausea, vomiting);
• hearing loss (hearing loss);
• noise in ears.

Symptomatic treatment of vestibular vertigo.

Forms of release

Tablets 8 mg, 16 mg and 24 mg.

Instructions for use and dosage

The drug is prescribed inside while eating. The dose should be selected individually depending on the response to treatment.

For adults, the dose is 24-48 mg per day.

Betaserc 8 mg - 1-2 tablets 3 times a day.

Betaserc 16 mg - 1 / 2-1 tablets 3 times a day.

Betaserc 24 mg - 1 tablet 2 times a day.

Tablet 16 mg and tablet 24 mg can be divided into 2 equal parts. To do this, put the tablet on a hard surface with a risk upward and press down on it with your thumb.

Improvement is sometimes observed only after several weeks of treatment, and a stable therapeutic effect - after several months of treatment. There is evidence that the administration of the drug at the onset of the disease prevents its progression and / or hearing loss at later stages.

In elderly patients, as well as in patients with renal and / or hepatic insufficiency, dose adjustment is not required.

Side effect

• nausea, vomiting;
• dyspepsia;
• gastrointestinal pain;
• bloating;
• angioedema;
• hives;
• itching;
• rash;
• anaphylactic reaction.

Contraindications

• hypersensitivity to the components of the drug;
• in children and adolescents under the age of 18 due to the lack of data on efficacy and safety.

Application in pregnancy and lactation

There are insufficient data on the use of Betaserc in pregnant women. The potential risk to humans is unknown. The use of Betaserk during pregnancy is possible only if the intended benefit to the mother exceeds the potential risk to the fetus.

It is not known whether betagistin is excreted in breast milk. Do not prescribe the drug during breastfeeding. The question of the appointment of Betaserk should be taken only after comparison of the benefits of breastfeeding with the potential risk for an infant.

special instructions

With caution should prescribe the drug to patients with peptic ulcer of the stomach or duodenum in the anamnesis. During the use of the drug, patients with pheochromocytoma and bronchial asthma should be under medical supervision.

Impact on the ability to drive vehicles and manage mechanisms

It is believed that the effect of betahistine on the ability to manage motor transport and other mechanisms is absent or insignificant, since it has not been found in clinical studies related to the use of betahistine that effects potentially affecting this ability.

Drug Interactions

In vivo studies aimed at studying the interaction with other drugs have not been conducted.

In vitro studies suggest that there is no inhibition of the activity of cytochrome P450 isoenzymes in vivo.

The patient should inform the doctor about taking any medications now or in the recent past.

Analogues of the drug Betaserc

Structural analogs for the active substance:

• Asnithon;
• Betaver;
• Betagistin;
• Betagistin hydrochloride;
• Betahistine dihydrochloride;
• Betacentrine;
• Vasoserk;
• Vestibo;
• Vestap;
• Denoise;
• The micrometer;
• Tagist.

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