En DE FR ES PL
Preductal - instructions for use, reviews, analogs and formulations (tablets 20 mg and 35 mg MB MP) of a medicament for the treatment of coronary heart disease in adults, including during pregnancy and lactation

Preductal - instructions for use, reviews, analogs and formulations (tablets 20 mg and 35 mg MB MP) of a medicament for the treatment of coronary heart disease in adults, including during pregnancy and lactation

In this article, you can read the instructions for using the drug Preductal. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Preductal in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Preductal in the presence of existing structural analogues. Use for the treatment of coronary heart disease and prevention of angina attacks in adults, children, as well as in pregnancy and lactation.

 

Preductal MB - prevents a decrease in the intracellular content of ATP by maintaining the energy metabolism of cells in a state of hypoxia. Thus, the drug ensures the normal functioning of membrane ion channels, transmembrane transfer of potassium and sodium ions and preservation of cellular homeostasis.

 

Trimetazidine (the active ingredient of the drug Preductal) slows the oxidation of fatty acids by selective inhibition of long chain 3-ketoacetyl-CoA thiolase, which leads to an increase in glucose oxidation and the restoration of conjugation between glycolysis and oxidative decarboxylation and causes myocardial protection from ischemia. Switching of oxidation of fatty acids to glucose oxidation underlies antianginal action of trimetazidine.

 

It has been experimentally confirmed that Preductal has the following properties:

  • maintains the energy metabolism of the heart and neurosensory organs during ischemia;
  • reduces the magnitude of intracellular acidosis and the degree of changes in the transmembrane ion flow that occurs with ischemia;
  • lowers the level of migration and infiltration of polynucleated neutrophils in ischemic and reperfusion tissues of the heart;
  • reduces the size of myocardial damage;
  • does not directly affect the parameters of hemodynamics.

 

In patients suffering from angina, Preductal:

  • increases coronary reserve, thereby slowing the development of ischemia caused by physical exertion, starting from the 15th day of therapy;
  • limits severe fluctuations in blood pressure caused by physical exertion, without any significant changes in heart rate;
  • significantly reduces the frequency of angina attacks and the need for short-acting nitroglycerin;
  • improves the contractile function of the left ventricle in patients with ischemic dysfunction.

 

In clinical studies of 2 months, it was shown that adding Presedtal MV 35 mg to Atenolol at a dose of 50 mg after 12 hours resulted in a significant slowdown in the onset of ischemic depression in the ST segment during exercise tests.

 

Pharmacokinetics

 

After taking the drug, the drug is rapidly absorbed. Eating does not affect the pharmacokinetic properties of the drug. It is excreted from the body mainly by the kidneys in unchanged form.

 

Indications

  • cardiology: prolonged therapy of IHD, prevention of attacks of stable angina (monotherapy or as part of combination therapy);
  • ENT diseases: treatment of cochlear-vestibular disorders of ischemic nature, such as dizziness, tinnitus, hearing impairment;
  • ophthalmology: chorioretinal disorders with ischemic component.

 

Forms of release

 

Tablets coated with 20 mg and 35 mg (Preductal MR).

 

Instructions for use and dosing regimen

 

Preductal MV is prescribed 1 tablet 2 times a day during meals in the morning and in the evening. The duration of therapy is set individually.

 

Tablets I take inwards whole, without chewing and washing down with water.

 

Side effect

  • stomach ache;
  • diarrhea;
  • dyspepsia;
  • nausea, vomiting;
  • dizziness;
  • headache;
  • extrapyramidal symptoms (tremor, rigidity, akinesia), reversible after drug withdrawal;
  • a feeling of palpitations;

  • extrasystole;

  • tachycardia;

  • marked decrease in blood pressure;

  • Orthostatic hypotension, which may be accompanied by general weakness, dizziness or loss of balance, especially with the simultaneous use of antihypertensive drugs;

  • flushes of blood to the skin of the face;
  • skin rash;
  • itching;
  • hives;
  • asthenia.

 

Contraindications

  • marked renal failure (CC less than 15 ml / min);
  • hypersensitivity to the components of the drug;
  • children and adolescents under the age of 18.

 

Application in pregnancy and lactation

 

In experimental studies, the teratogenic effect of Trimetazidine has not been established. However, due to the lack of clinical data, the drug is not recommended for use in pregnancy.

 

It is not known whether trimetazidine is excreted in breast milk. Therefore, if it is necessary to prescribe the drug during lactation, breastfeeding should be stopped.

 

Use in children

 

Due to the lack of sufficient clinical data, it is not recommended to prescribe the drug to children and adolescents under the age of 18 years.

 

Application in elderly patients

 

Caution should be used to prescribe Preductal MB to elderly patients over 75 years of age who may have an increase in exposure.

 

special instructions

 

Preductal MB is not intended for relief of angina attacks and is not indicated for the initial course of therapy for unstable angina or myocardial infarction at the prehospital stage or in the first days of hospitalization.

 

In the case of an angina attack, treatment should be reviewed and adapted (drug therapy or revascularization procedure).

 

MB reductase may cause or worsen symptoms of parkinsonism (tremor, akinesia, tone increase), therefore, regular monitoring of patients, especially of the elderly, should be carried out. In doubtful cases, patients should be referred to a neurologist for an appropriate examination.

 

When motor disorders such as Parkinsonism symptoms, restless legs syndrome, tremor, Romberg pose instability and gait unsteadiness occur, Preductal MB should be finally abolished.

 

Such cases are rare and symptoms usually pass after discontinuation of therapy: in most patients - within 4 months after discontinuation of the drug. If the symptoms of parkinsonism persist for more than 4 months after discontinuation of the drug, you should consult a neurologist.

 

There may be cases of falls associated with instability in the Romberg position and the "shakiness" of the gait or pronounced decrease in blood pressure, especially in patients taking antihypertensive drugs.

 

Caution should be used to prescribe Preductal MB to patients who may have an increase in exposure:

  • with renal insufficiency of moderate and severe degree;
  • in elderly patients older than 75 years.

 

Impact on the ability to drive vehicles and manage mechanisms

 

In the course of clinical studies, there was no evidence of the influence of Preductal MB on hemodynamics, however, in the period of post-marketing use, cases of dizziness and drowsiness were observed, which could affect the ability to drive vehicles and carry out work requiring increased rates of physical and mental reactions.

 

Drug Interactions

 

Drug interaction of the drug Preductal MP is not described.

 

Analogues of the drug Preductal

 

Structural analogs for the active substance:

  • Angiosyl retard;
  • Antisthenes;
  • Antistene CF;
  • Vero-Trimetazidine;
  • Depenorm MB;
  • Carditrim;
  • Metagard;
  • Predizin;
  • Precardard;
  • Romekor;
  • Rimecor MB;
  • Tridoukard;
  • Trimectal;
  • Trimectal;
  • Trimetazide;
  • Trimetazidine;
  • Trimetazidine MB;
  • Trimetazidine-Biocom MB;
  • Trimetazidine-ratopharm;
  • Trimetazidine dihydrochloride;
  • Trimitard MV.

Similar medicines:

Other medicines:

Reviews (68):
Guests
tanto
A good drug for heart pain.For a long time my grandmother was tormented by bouts of pain under the scapula, which did not remove either Validol, Neither her tincture of any peonies and other herbs. They sent her to the neurologist and to the therapist and the ECG did which showed nothing. Until finally, they sent her to a cardiologist who pointed out heart problems and prescribed Preductal MV, which, after a month of receiving the scheme, helped our grandmother get rid of the pains under the scapula (as the cardiologist said it is an analogue of heart pains). Plus, the head became better, it began to forget less, memory improved in the grandmother, so that from all sides a good medicine, true and expensive. MV by the way means a modified release, that is, it acts gradually and continuously, which increases the effect of treatment.
Guests
Love
At me a combined vice of MK stenosis of valves and insufficiency of valves, -2,65sm2. The doctor assigned me a preductal - would it be useful?
Administrators
admin
Love, The doctor also appointed you for some purpose (he can support the heart, maybe for what else). It was necessary to ask the specialist you appointed, why and for what purpose he did it.The medication itself can not harm, but the appropriateness depends on the diagnosis - including those accompanying the underlying disease. The fact that the stenosis from Preductal is unlikely to change - this is my belief, the rest to you to the doctor.
Guests
Svetlana
Preductal did not help me after 4 tablets at night did not sleep well. I crushed my throat and there was dryness in my nose at night. And so two nights. His stomach ached. And the adrenal gland.
Guests
Sasha
My opinion is that Preductal works. Sam repeatedly resorted to his help.
Guests
Antonina
Accepted deprenorm and presidin. The result is positive. Periodically I accept.
Guests
somm
Yes, they helped me.
Guests
Vera
I'm 38, and I'm practically healthy. But when I'm very tired, but still a lot of things, I take 1 tablet of a preductal. The effect is magical. Only in the evening it is not necessary. Do not fall asleep.
Guests
IRINA
For several years I have been taking preductal,packaging is not cheap, probably already in the area of ​​a thousand, and today the endocrinologist has prescribed trimetazidine mv and it turns out to be practically the same preductal, but costs 130r.
Guests
Anya
I began to have pain in the heart after the preductal, after the first pill, burning, pressure, shooting pain. On the third day, the reception was much worse, I had to lie because of the pain, I stopped taking it, everything went away in a day. It is interesting, why it is appointed, as absolutely harmless means, without contraindications. In the package, too many tablets, given that the drug may not be suitable, and the medicine is expensive.
Guests
Mayan
After taking the reductase, the tachycardia begins at night. Can drink only in the morning. The diagnosis is widespread ohz, myocardiosclerosis is myocarditis. nmk -1 ntk -2 primary osteochondrosis with knee joint damage.
Administrators
admin
Mayan, I see the error in taking you drug. Preductal MB is taken 1 tablet 2 times a day, and you take 1 tablet a day.It is necessary that your cardiologist adjust the dosage. Yes, Preductal can cause a tachycardia, but its appearance may not be associated with taking the drug, but with the administration of another medication or in general indirectly (coincidence), so there is also an occasion to consult with the attending physician.
Guests
Lyudmila
I suffer from high blood pressure. I drink a lot of medicines. The doctor has written out yet Preductal MB. From the first day there were unpleasant sensations in the heart. Pain was not, but as it is not comfortable. I felt the heaviness, with the return to the shoulder blade. The reception is already a week. Perhaps the medicine is such a change? Can not you combine it with Lozap +, Konkor and Physiotens?
Administrators
admin
Lyudmila, Preductal is combined with all these drugs. Try to cancel it and see if any unpleasant sensations have disappeared. This component of treatment can be considered as additional, since Preductal is like a vitamin for the heart, and not the main treatment. If necessary, you can do without it.
Guests
Basil
Yesterday I took it for the first time. He listened ...There was a slight dizziness, anxiety ... After a minute. 5-7 norm. He fell asleep badly and for a long time. The first time I saw AD 120,110 / 70 in the evening, it was basically 90/60. After stenting, it took about 4 months. I think everything, can I still not take Preductal? Today I took just before meals, the same dizziness, a sense of anxiety ... It happened right away during a meal ...
Administrators
admin
BasilIf the doctor has prescribed Preductal (and your cardiologist should prescribe with your problem), then it is not too early. A pill is better to evaluate the day in 3-4 if it is not critical to health and is not pronounced. Perhaps you are winding yourself up. Try to ignore the medication, but if, after that, pobochka will remind you of yourself - this is an occasion to consult a cardiologist for advice and change the treatment schedule.
Visitors
Galina
Question. What analogues of preductal, more consistent with it - it is very expensive, cardiologists have prescribed to drink constantly.
Administrators
admin
Galina, All analogues specified in the instructions are 100% active, that is, they can be used in treatment as similar. But the question of replacement should still be agreed with the attending physician - there are few nuances of admission, since Preductal is taken by courses, and not constantly, and it confuses me in your appointment.
Guests
Lyudmila
When taking the first pill, there was an anxiety and a feeling of a presyncope. Carvalole helped, after a short time again a repeat. She called 03. The doctor in the hospital expressed doubt. I will make one more attempt.
Guests
olga
Pain under the right scapula, anxiety, flushes of blood to the face, weakness, also a feeling of a presyncope. I do not want to drink it anymore. It's a pity money - packing 60 tablets and not cheap.
Guests
Tatyana
The drug is effective, I went very well. There were pains under the scapula, ECG did not show any changes, but the therapist preshadal appointed to reinforce the heart muscle. I felt relieved, took it strictly on the recommendation, there were no side effects.
Guests
Natallia Mikhailovna
I am 65 years old. There was shortness of breath, swelling on the legs, sometimes (with physical exertion), the lips turn blue. Has addressed to the doctor. They diagnosed IHD, the doctor prescribed a preductal, I drink 15 tablets a day for 15 days, pains in my heart have passed, my lips have turned pink, but the swelling on my legs has not yet passed. All is well, but after taking the drug, the head is very sore and almost every day should take a pill of headache (citramone or trimol).
Guests
Gal
I use medicine when I am not able to go to work (IHD, GB, etc.). 2 years ago, the doctor prescribed several medications, including Panangin and Preductal (permanently). Of all this she left. Slut-but, I drank courses, with interruptions until several. months. In July I bought again - last week there was a strong shortness of breath when walking, legs became leaden, I had to slow down, breathe like a dog, terrible arrhythmia with loss of pulse, pressure shot at 120 from the usual 160. Three days on b / l, I go to an apartment with a dyspnea or shortness - here as me this vitamin (this day only has reached to check up it on responses). In the morning was the last pill - the rest.
Guests
Old Nick
11 years ago received a massive heart attack. After the main treatment, the doctor prescribed me, among other drugs, a preductal. Taken without any side effects, one course, as a maintenance therapy. There are no claims to the drug. The help from him was on his face - pain in the heart decreased, breathing was almost lost, and overall well-being became better. It is possible to write off all this for other drugs, but then, at least, from the preductal, there was no harm.
Guests
Lyudmila
I drink the second day of Preductal MR as prescribed by a doctor. At morning reception - podtashnivaet somewhere 1 hour. At evening - hardly longer. And the squeezing pain on the left in the chest and, as it were, the breathing stopped. I accept validol - a little easier in a few minutes. Do I need to take further of the drug in spite of these pimples or stop it?
Administrators
admin
LyudmilaMore similar not to side effects, but to the development of ischemia, heart failure. So I would not delay with the delivery of the ECG and a call to the doctor urgently.If I am mistaken and this is normal neuralgia or osteochondrosis, then I think that the admission of Preductal can be continued if nausea (which most likely can be from taking the drug) does not greatly interfere with normal life activity.
Guests
Lyudmila
I took the reductase MR two months. The state of health improved. A good vitamin for the heart!
Guests
Tatyana
Mom is 90 years old. She was prescribed a reductase. And the instructions say that the elderly are contraindicated. Whom to believe?
Administrators
admin
TatyanaThe instruction says that the drug Preductal should be prescribed with elderly patients (over 75 years old) with caution, since it is possible to increase its exposure, that is, the products of its metabolism can be more slowly excreted from the body of an elderly person, but this does not mean that the medicine is contraindicated. It requires more control over the patient's condition with dose adjustments or cancellations, depending on the situation.
Guests
Julia is 67 years old.
I have high blood pressure and tachycardia. The doctor appointed - Lozap and Preductal. I drink 2 months - I feel fine without side effects.
Guests
VAL'EVA OLYMPIAD IS 76 YEARS OLD
Trimectal took 4 days. The head hurts, the back of the head hurts, the night has not slept well. I have a blood pressure of 190/100 - 160/60, my heart ached.
Guests
Ольга, 61 years old
It was a feeling of pressure in the chest, lack of air during fast walking, pressure jumps, cardiogram - normal. I take the drug for 2 weeks, I feel better, there are no side effects.
Guests
Olga
Has bought or purchased on purpose or appointment of the cardiologist Preductal MB 35 mg. After the third pill started to vomit. Unpleasant, disturbing feeling. Today I cut the tablet in half (thus I myself reduced the dose not to throw away the same package, going for the same in 20 mg). Still unpleasant sensations. At me an arrhythmia + from pressure I accept Arifon retard and Aprovel of 75 mg. From 150 mg my blood pressure dropped to 100 units.
Visitors
KVN
By appointment, the doctor took a course of preductal MB (two packs of 60 tablets each), the effect is positive.Tell me how soon or after what time and whether you need to repeat this course? Since I'm a pensioner, I'm still interested in this question (because of the price). Trimetazidine - will it be the same or not? Thank you.
Administrators
admin
KVN, I try to adhere to the treatment of specific patients those drugs that give a positive effect and do not change them to analogues. Because the original is suitable, but the generic is not. You can try, if the issue of price is significant, then there is no choice. In most cases, the result is positive, but there are also misfires.

Two courses of admission Preludtal MV per year I think normal and do not appoint my patients anymore. To whom it is necessary simply I extend the duration of the course (up to 2 months).
Guests
Lyudmila
After taking the preductal, there were pains in the abdomen, flatulence.
Guests
Galina
I drink it for two days. After the morning pill, everything is normal, no sensations, after the evening pill 30-40 minutes later there is a pain in my heart.
Guests
Nisad
To me 66, a long-term hypothyrosis. Therefore, atherosclerosis develops, and the initial stage of angina, the pressure rises from 90 to 160. The cardiologist after the echogram prescribed - in the morning concor 2.5, in the evening preductal. From the first day of admission, night swelling to the eyes and pains in the heart stopped. But the pressure is still floating up and down.
Visitors
Sofia
My mother (79 years old) was prescribed Preductal and Lozap. At first everything was fine, and now she has terrible swelling on her face like a bee stings. What to do? Why is this happening?
Administrators
admin
SofiaFor Preduktal, edematous syndrome is not typical. Lozap can cause swelling, but it is better to show the doctor's mom, so as not to miss an allergic reaction, and this is a threatening health and life condition. I fully admit that puffiness can be in no way connected with taking medications (as I understood from the question, she took them earlier), but you can understand this only by looking at the patient's medical history and the appearance of swollen tissues. On the Internet, you can hardly find an acceptable solution.
Guests
Nina
Is there a withdrawal syndrome in the preductal?
Administrators
admin
Nina, No. Preductal MB or OD has no withdrawal syndrome and the drug can be withdrawn at the same time.
Guests
Olga
In 2003, at 48 years, suffered a massive heart attack, barely survived. All these years, of course, I take various cardiac preparations, but in recent years, pains have become especially acute with physical exertion or I'm very nervous, I immediately take Preductal MV. He helps me relieve the pressing pains in my heart, but after all, each person has a different organism and therefore, of course, to whom he helps, and who does not and it is difficult to judge a good drug or not, because I also have cholesterol, and bradycardia, low blood pressure and a rare pulse. So I feel that helps, then I accept.
Tell me, please, what consequences can the reception of a preductal or trimetazidine have (recommended is the preductal) with a neurologist diagnosed before the onset of a shaky Romberg pose?
Administrators
admin
Natalia 08042015, Everything is in the instruction: "When there are motor disorders such as Parkinsonism symptoms," restless legs "syndrome, tremor, instability in Romberg's pose and" gait "gait, Preductal MB should be finally canceled."

So further on such a question should puzzle your neurologist if there is damage to the brain structures (although it may not be), so that he assesses the permissibility of using the drug Preductal in this patient.
Guests
Love
I was very helped by the reductase. True, I took him for three or four months, then moved to another city and the treatment stopped, nothing bothered me. And now for almost two years I have been taking antistene. The noise in my head disappeared, I was ringing in one ear. The doctor tells me to continue the treatment.
Guests
Tatyana
When taking this drug, the head became very dizzy. After stopping the reception of dizziness stopped.
Guests
Taisia
In the morning I drink preduktal MR 35 mg.In the evening zorem Czech (in our normodipin) on the floor of the pill. Since zorev 5 mg is at risk and is divided into 2 and 3 mg, I take 2 or 3 mg respectively in the evening. I had shortness of breath, climb freely in the hill, without slowing down. The diagnosis is left ventricular myocardial hypotrophy. I drink regularly 3 months. I'm going to see a cardiologist about the clarification of taking medications, because I read that the preductal should not be drunk constantly, but with interruptions.
Guests
Galina
I accept preductal the 2nd month. Everything would be fine, but there were foot swelling.
Guests
Tatyana
Very good drug. I had no side effects. The positive effect felt almost immediately. There was a feeling of ease, dyspnea was gone, my heart is working quietly. An excellent product.
Guests
Olga
Mother 78 years. After taking preductal for the purpose, 2 times a day, there are pain in the heart, nausea, vomiting, worsening of the general condition.
Guests
Galina
I have been taking courses for Preductal CF for a long time, I always felt an improvement in my state of health.And this time I decided to buy Premedtal OD with prolonged release to take the drug 1 time a day in the morning. The instructions say that the pronounced therapeutic effect comes from the 14th day of application. I drink the third week, I still do not feel the effect.
Guests
Olga
I was 68 years old when a doctor prescribed a preductal and said that I had an electrocardiogram worse and I had to drink vitamin for the heart. After a while, heart attacks began, a strong palpitations, weakness, and so on every day, then several times a day. I thought it was time to die. Then she guessed that the so-called "vitamins for the heart" were to blame, she threw them to drink and after 2 days everything went back to normal. Now 2 years I treat all sorts of medicines with great care.
Guests
love
The first time I repressed the saw 6 years ago and everything was fine. But since last year I can not stand it. Causes a strong extrasystole and its analogues also work. Even two cases of arrhythmia are fixed. And the doctor appoints him again. Independently stopped his reception.
Guests
Yudlll
Preductal is a very expensive drug, but it's of little use. I drink five years.
Guests
alla
I am 55 years old. Pain in the heart began. The doctor attributed the preductal. Saw 2 months. Pain was not. Two days after stopping the medication, pains in the heart started again.
Guests
Tatyana
Six years ago, Cardiologist appointed Preductal. I drink all these years, when the pain in my heart or it becomes difficult to breathe. Helps at once. I did not go to the doctor any more. A good drug. I like. I am 63 years old.
Guests
Alexandra Vasilievna
I've been on drugs for four years, it helps very well, but the pressure is jumping lately. At me a hypertonia, happens 170 on 90, I drink captopril, falls 105/60 and the head strongly hurts, constantly I accept lopaz.
Guests
Ablina Lyudmila
Pugh Preductal CF second month. In general, well-being improved, but worse began to fall asleep.
Visitors
valent.spb
It would be desirable to learn or find out, what preparation from group Trimetazidina is the original, and what dzhenerikami. For example, preductal, antisthene, etc. Thank you.
Administrators
admin
valent.spb, Trimetazidine is not really branded, because the active substance is not protected by patents. Look at the manufacturer who is more trusted. Now on the market of medicines in Russia, almost all of Russia's production or CIS. On the basis of trimetazidine, the Israeli-German Trimetazidine Teva is only produced in foreign countries, the rest is Russia, the CIS, Poland, Romania.
Visitors
ma129336
Good afternoon. To the husband the cardiologist has appointed or nominated preduktal 80 mg 1 time a day during meal. He has hypertension, ischemic disease and bradycardia (pulse 50 - 55). Takes a few years for a tween 10 + 80 without complications. After taking the reductase in the next 4 days, the pulse 46. There are no other complications. Thank you.
Visitors
ma129336
Can the reductase act on the heart rate in the direction of decrease?
Administrators
admin
ma129336, Tachycardia, as a side effect of using the drug Preductal, is described in the manual,but about bradycardia or a decrease in heart rate in relation to this drug there is no such information. If only consider it as an individual response of the patient to taking this medication.
Visitors
ma129336
Hello. The husband takes several years of twintus 10 + 80, appointed after a survey in the cardiology of the City Clinical Hospital of 51 Moscow. The drug lowers blood pressure well, but recently there has been a pronounced bradycardia 44 - 46, sometimes 42. Normally, he always had a pulse of 55 - 56. In this case, his ECG in 2011 shows a complete blockade of the right leg of the bundle of His. Age of 77 years. Recently, the chief cardiologist in GP 218 in Moscow, the doctor said that nothing special, said that will help preduktal. Our actions? Thank you.
Administrators
admin
ma129336To interfere with the treatment that another doctor appointed, I can not, but the bradycardia as an infrequent side effect is stated in the instructions to the Twist drug. Therefore, or you trust your doctor and take Preductal, or adjust the treatment with other drugs.The difference between the heart rate is 55 and 45 bpm. is also small, so a detailed in-depth analysis of the situation is needed here, plus monitoring of blood pressure and pulse within a week or two, plus ECG, ultrasound, daily monitoring according to the indications.
Tell me, please, what are the differences between the preductal and rimecor? Mom was appointed precisely rimecor. She has hypertension, ischemic heart disease, a recent heart attack six months ago.
Administrators
admin
Natalia 08042015, Produktal of prolonged action. If Rimecor MB is used, it is also prolonged, but it is necessary to look at the prescribed dosages of these medications, because they have the active substance, and the dosages for all tablets or capsules are different. In my practice, I often use Preductal OD.

Rules for publishing reviews and visitor questions