Omez - instructions for use, analogs, reviews and release forms (tablets, capsules 10 and 20 mg, powder (Insta)) drugs for the treatment of peptic ulcer of the stomach and duodenum in adults, children and in pregnancy

In this article, you can read the instructions for using the drug Omez. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Omez in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Omezes in the presence of existing structural analogs. Use for the treatment of peptic ulcer of the stomach and duodenum, as well as erosive and ulcerative lesions of the digestive tract in adults, children,as well as during pregnancy and lactation. Types of drug Omez D and Insta and their difference from the original Omez.

Omez - antiulcer drug. Omeprazole (an active ingredient in the preparation of Omez) inhibits the enzyme H + -K + -ATP-asu (proton pump) in parietal cells of the stomach and blocks the final stage of the synthesis of hydrochloric acid. This leads to a decrease in the level of basal and stimulated secretion, regardless of the nature of the stimulus.

After a single dose of the drug, omeprazole is administered within the first hour and lasts for 24 hours, the maximum effect is achieved after 2 hours. In patients with duodenal ulcer, the omeprazole dose of 20 mg maintains an intragastric pH of 3 units. within 17 hours After discontinuation of the drug secretory activity is completely restored after 3-5

Pharmacokinetics

Omez quickly absorbed from the digestive tract. Omeprazole is almost completely metabolized in the liver. It is excreted mainly by the kidneys in the form of metabolites.

Indications

• peptic ulcer of the stomach and duodenum;
• reflux esophagitis;
• erosive and ulcerative lesions of the stomach and duodenum associated with the administration of NSAIDs, stress ulcers;
• erosive and ulcerative lesions of the stomach and duodenum, associated with Helicobacter pylori (as part of complex therapy);
• Zollinger-Ellison syndrome.

Forms of release

There is an erroneous opinion that there is such a form of release of the drug as a tablet, rush to grieve, and maybe please - it is produced in all forms, except for tablet.

Capsules soluble in the intestine 10, 20 and 40 mg.

Omez D, contains, in addition to omeprazole, also domperidone, which enhances the intestinal peristalsis and promotes digestion. In capsules of 20 mg.

Омез �?нста - a powder for preparation of a suspension for reception inside, with a pleasant smell, very well approaches or suits children.

Instructions for use

Take it by mouth with a small amount of water; the contents of the capsule can not be chewed.

Peptic ulcer of duodenum in the phase of exacerbation: 20 mg (1 caps.) Per day for 2-4 weeks, in resistant cases - up to 40 mg (2 caps.) Per day.

Stomach ulcer in the acute phase and erosive-ulcerative esophagitis: 20-40 mg (1-2 caps.) Per day for 4-8 weeks.

Erosive-ulcerative lesions of the gastrointestinal tract caused by the intake of NSAIDs: 20 mg (1 caps.) Per day for 4-8 weeks.

Eradication Helicobacter pylori: 20 mg (1 caps.) 2 times a day for 7 days in combination with antibacterial agents.

Anti-relapse treatment of peptic ulcer of the stomach and duodenum: 20 mg (1 caps.) Per day.

Antrepid treatment of reflux esophagitis: 20 mg (1 caps.) Per day for a long time (up to 6 months).

Zollinger-Ellison syndrome: the dose is selected individually depending on the initial level of gastric secretion, usually starting from 60 mg per day. If necessary, the dose is increased to 80-120 mg per day, in this case it is divided into 2 divided doses.

Omez D

Take inside, washed down with a small amount of water, 1 capsule 2 times a day, 15-20 minutes before meals.

Omez Insta

The drug should be taken orally 30 minutes before eating. Pour the contents of the sachet into a cup, add 1-2 tablespoons of water (do not use other liquids or food products), stir well until a homogeneous suspension is obtained and immediately drink. If necessary, you can drink a small amount of water.

For a quick relief of the symptoms of heartburn, a single dose of 20 mg is sufficient.

Side effect

• diarrhea or constipation;
• nausea, vomiting, flatulence;
• abdominal pain;
• dry mouth;
• violation of taste;
• stomatitis;
• hepatitis (including jaundice);
• headache, dizziness;
• agitation, drowsiness, insomnia;
• paresthesia;
• depression;
• hallucinations;
• muscle weakness;
• myalgia, arthralgia;
• leukopenia, thrombocytopenia;
• agranulocytosis, pancytopenia;
• itching, hives, angioedema;
• bronchospasm;
• anaphylactic shock;
• impaired vision;
• peripheral edema;
• increased sweating.

Adverse reactions occur rarely and are reversible.

Contraindications

• childhood;
• pregnancy;
• lactation period;
• hypersensitivity to the drug.

Application in pregnancy and lactation

The drug is contraindicated for use in pregnancy and lactation.

special instructions

Before the start of therapy, it is necessary to exclude the presence of a malignant process (especially with peptic ulcer disease), because treatment, masking symptoms, can delay the setting of the correct diagnosis.

Taking the drug simultaneously with food does not affect its effectiveness.

In patients with severe hepatic insufficiency, the daily dose should not exceed 20 mg.

Drug Interactions

Long-term use of Omega in a dose of 20 mg once a day in combination with caffeine, theophylline, piroxicam, diclofenac, naproxen, metoprolol, propranolol, ethanol, cyclosporine, lidocaine, quinidine and estradiol did not lead to a change in their concentrations in the blood plasma.

No interaction with concomitant antacids was noted. Changes the bioavailability of any drug, the absorption of which depends on the pH (for example, iron salts).

Analogues of the drug Omega

Structural analogs for the active substance:

• Gastrozole;
• Demeprazole;
• Zhelezolic;
• A zerocide;
• Losek;
• Omesol;
• Omekaps;
• Omeprazole;
• Omepros;
• Omeface;
• Omizak;
• OmiPix;
• Omitox;
• Ortanol;
• Ozid;
• Pepticum;
• Petipack;
• Pomez;
• Romesque;
• Ulzol;
• Ulcozol;
• Ultop;
• Helicid;
• Helol;
• Cisagast.

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