Kagocel - instructions for use, reviews, analogs and forms of release (tablets 12 mg) drugs for the treatment and prevention of influenza, ARVI and herpes in adults, children and during pregnancy and lactation. Composition
In this article, you can read the instructions for using the drug Kagocel. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Kagocel in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Kagocel with available structural analogues. Use for the treatment and prevention of influenza, ARVI and herpes in adults, children, as well as during pregnancy and lactation (lactation). Composition of the preparation.
Kagocel - antiviral drug. Inductor synthesis of interferon.
It causes the formation in the body of the so-called late interferon, which is a mixture of alpha and beta interferons, which have high antiviral activity. Kagocel causes the production of Interferon in almost all cell populations that participate in the antiviral response of the body: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When administered in one dose of the drug Kagocel titer interferon in the serum reaches its maximum values after 48 hours. The interferon response of the body to the administration of Kagocel is characterized by a prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of accumulation of interferon in the intestine when taking the drug inside does not coincide with the dynamics of the circulating interferon titers. In the blood serum, the content of interferon reaches high values only 48 hours after taking Kagocel, while in the intestine the maximum production of interferon is observed after 4 hours.
The greatest effectiveness in the treatment with Kagocel is achieved with its appointment no later than the 4th day after the onset of acute infection.For preventive purposes, the drug can be used at any time, incl. and immediately after contact with the infectious agent.
Composition
Copolymer gossypol (one of the pigments of cotton, natural polyphenol, toxic in a free form) with carboxymethyl cellulose + auxiliary substances.
Pharmacokinetics
When administered orally, about 20% of the administered dose of the drug enters the total blood flow. 24 hours after ingestion, the drug accumulates mainly in the liver, to a lesser extent - in the lungs, thymus, spleen, kidneys, lymph nodes. Low concentration is noted in adipose tissue, heart, muscles, testes, brain, blood plasma. The low content in the brain is explained by the high molecular weight of the drug, which hinders its penetration through the BBB. Output is mainly through the intestine: after 7 days after intake, 88% of the administered dose is withdrawn from the body, including 90% with feces and 10% with urine. In the exhaled air the drug was not detected.
Indications
- prevention and treatment of influenza and other ARVI in adults and children aged 6 years and older;
- treatment of herpes in adults.
Forms of release
Tablets 12 mg. Special pediatric form of the drug is not marked.
Instructions for use and dosage
The drug is taken orally.
Adults for treatment of influenza and SARS are prescribed in the first 2 days - 2 tablets 3 times a day, in the next 2 days - 1 tablet 3 times a day. In total, the course lasts 4 days - 18 tablets.
Prevention of influenza and ARVI is carried out by 7-day cycles: 2 days - 2 tablets once a day, break for 5 days. Then the cycle is repeated. The duration of the preventive course varies from 1 week to several months.
For the treatment of herpes, 2 tablets are prescribed. 3 times a day for 5 days. In total for a course lasting 5 days - 30 tablets
Children aged 3 to 6 years for treatment of influenza and SARS are prescribed in the first 2 days - 1 tablet 2 times a day, in the next 2 days - 1 tablet 1 time per day. In total, the course lasts 4 days - 6 tablets.
Children aged 6 years and older for treatment of influenza and SARS are prescribed in the first 2 days - 1 tablet 3 times a day, in the next 2 days - 1 tablet 2 times a day. In total, for a course of 4 days - 10 tablets.
In children aged 3 years and over, the prevention of influenza and ARVI is carried out by 7-day cycles: 2 days - 1 tablet 1 time per day, break for 5 days, then repeat the cycle. The duration of the preventive course is from 1 week to several months.
Side effect
- allergic reactions.
Contraindications
- pregnancy;
- lactation period (breastfeeding);
- children under 3 years;
- deficiency of lactase, lactose intolerance, glucose-galactose malabsorption;
- increased individual sensitivity.
Application in pregnancy and lactation
The drug is contraindicated for use in pregnancy and lactation (breastfeeding).
Kagocel, when prescribed in therapeutic doses, is non-toxic, does not accumulate in the body. The drug does not have mutagenic and teratogenic properties, it is not carcinogenic and does not have embryotoxic effect.
Use in children
Kagotsel is contraindicated in children under 3 years of age.
Children aged 3 to 6 years for treatment of influenza and SARS are prescribed in the first 2 days - 1 tablet 2 times a day, in the next 2 days - 1 tablet 1 time per day. In total, the course lasts 4 days - 6 tablets.
Children aged 6 years and older for treatment of influenza and SARS are prescribed in the first 2 days - 1 tablet 3 times a day, in the next 2 days - 1 tablet 2 times a day. In total, for a course of 4 days - 10 tablets.
In children aged 3 years and older, the prevention of influenza and ARVI is carried out by 7-day cycles: 2 days - 1 tablet 1 time per day, break for 5 days,then the cycle is repeated. The duration of the preventive course is from 1 week to several months.
special instructions
To achieve a therapeutic effect, Kagocel should be taken no later than the 4th day after the onset of the disease.
Kagocel is well combined with other antiviral drugs, immunomodulators and antibiotics.
Drug Interactions
With the simultaneous use of Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect is observed (they enhance each other's action).
Analogues of the drug Kagocel
Kagocel does not have structural analogs for the active substance.
Analogues for the pharmacological group (antiviral agents):
- Avonex;
- Alloferon;
- Altevir;
- Alfaferon;
- Amizon;
- Amiksin;
- Anaferon;
- Anaferon child;
- Arbidol;
- Acyclovir;
- Bonaphoton;
- Valaciclovir;
- Valtrex;
- Vivorax;
- Virazole;
- Virolex;
- Viferon;
- Genferon;
- Gerpevir;
- Herpferon;
- Groprinosin;
- Zovirax;
- Ingavirin;
- Interferon;
- Inferon;
- Lavomax;
- The Medovar;
- Nevirapine;
- Neovir;
- Oxolin;
- Panavir;
- Reaferon EU Lipint;
- Relenza;
- Remantadine;
- Ribavirin;
- Rimantadine;
- Tamiflu;
- Tyloron;
- Famvir;
- Famciclovir;
- Cyclovir;
- Epigenum sex;
- Epigen labial;
- Ergoferon.
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