Diazolin - instructions for use, analogs, reviews and release forms (tablets and pills 50 mg and 100 mg) drugs for the treatment of allergies in adults, children and pregnancy
In this article, you can read the instructions for using the drug Diazoline. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Diazolin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Diazoline in the presence of existing structural analogues. Use to treat allergic diseases (hives, eczema, rhinitis) in adults, children, as well as during pregnancy and lactation.
Diazoline - blocker of histamine H1 receptors, ethylenediamine derivative. Has antiallergic, antipruritic, antiexudative, and also weak sedation. It has m-cholinoblocking properties.
Pharmacokinetics
After oral administration, it is rapidly absorbed from the digestive tract. Virtually does not penetrate the blood-brain barrier. Metabolised in the liver by methylation. It is excreted by the kidneys.
Indications
- hay fever;
- hives;
- eczema;
- itching;
- allergic rhinitis;
- allergic conjunctivitis;
- skin reaction after an insect bite;
- bronchial asthma (as part of combination therapy).
Forms of release
Tablets of 50 mg and 100 mg.
Dragee 50 mg and 100 mg.
Instructions for use and dosage
Adults and children over 10 years of age - 100-300 mg per day. The daily dose for children aged 5-10 years is 100-200 mg; 2-5 years - 50-150 mg; up to 2 years - 50-100 mg.
Side effect
- dry mouth;
- Dyspeptic phenomena due to irritation of the gastric mucosa;
- dizziness;
- paresthesia;
- increased fatigue;
- tremor;
- drowsiness;
- granulocytopenia, agranulocytosis;
- dysuria.
Contraindications
- hypertrophy of the prostate;
- angle-closure glaucoma;
- peptic ulcer of the stomach and duodenum;
- inflammatory diseases of the digestive tract in the phase of exacerbation;
- increased sensitivity to mebhydroline (active ingredient of Diazoline);
- pyloric stenosis;
- epilepsy;
- disorders of the heart rhythm (having a vagolytic effect, can improve AV-conduction and promote the development of supraventricular arrhythmias);
- pregnancy;
- lactation period.
Application in pregnancy and lactation
Diazolin is contraindicated in pregnancy and lactation (breastfeeding).
special instructions
Use with caution in hepatic and / or renal failure (dosage and interval between doses may be required).
Impact on the ability to drive vehicles and manage mechanisms
During the treatment period, one should refrain from engaging in potentially dangerous activities requiring increased attention and speed of psychomotor reactions (driving vehicles or working with mechanisms).
Drug Interactions
Mebhydroline increases the effect of sedatives and ethanol (alcohol).
Analogues of drug Diazolin
Structural analogs for the active substance:
- Mebhydrogen;
- Mebhydroline Napadisylate.
Analogues on the class of medicinal effect (antihistamines):
- Aviomarine
- Alerza
- Allergodyl
- Allergoferon
- Allertec
- Allergies
- Astemizole
- Betadrine
- Bonin
- Bronal
- Vibrocil
- Gismanal
- Gistalong
- Histafen
- Histimet
- Gifast
- Glenceth
- Desloratadine
- Dimebon
- Dimedrol
- Dinox
- Donormil
- Dramina
- Zincet
- Zirtek
- Zodak
- Kestin
- Claritin
- Clarifer
- Clemastine
- Xizal
- Letizen
- Lomilan
- Loratadin
- Lordestine
- Mebrogroline
- Parlazin
- Pipolphen
- Rapido
- Rupafin
- Semprex
- Ciel
- Sowentol
- Suprastin
- Tavegil
- Telfast
- Fexadine
- Femizol
- Fenistil
- Fenkarol
- Chloropyramine
- Cezera
- Cetirizine
- Cetiriax
- Cetrin
- Erespal
- Erius
- Erolin.
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