Driptan - instructions for use, reviews, analogs and formulations (5 mg tablets) drugs for the treatment of urinary incontinence and nocturnal enuresis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Driptane. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Driptan in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Driptan analogs in the presence of existing structural analogues. Use for the treatment of urinary incontinence and nocturnal enuresis in adults, children, as well as in pregnancy and lactation. Composition of the preparation.

Driptane m-cholinoblocker from the group of tertiary amines. Along with moderate m-holinoblokiruyuschey activity has the ability to directly affect the smooth muscles of internal organs (myotropic antispasmodic effect). Eliminates spasms and lowers the tone of smooth muscles of the internal organs: gastrointestinal tract, biliary tract, uterus, urinary tract, incl. Bladder. With a neurogenic bladder, oxybutynin relaxes the detrusor of the bladder, reduces spontaneous reductions in detrusor, increases the capacity of the bladder, reduces the frequency of urinary urges.

Composition

Oxybutynin hydrochloride + excipients.

Pharmacokinetics

After ingestion Cmax is reached after 45 minutes, the concentration value is proportional to the applied dose. In elderly people the half-life increases.

Indications

• urinary incontinence due to unstable bladder function of a neurogenic nature (detrusor hyperreflexion, for example, in multiple sclerosis or spina bifida) or idiopathic nature;
• nocturnal enuresis in children older than 5 years (in the form of monotherapy or in combination with other medicines).

Forms of release

Tablets 5 mg.

Instructions for use and course treatment

Is taken internally. Adults - 5 mg 2-3 times a day. In elderly patients at the beginning of treatment, 2.5-3 mg twice a day is used, then, if necessary, gradually increase the dose to 5 mg twice a day.

Children older than 5 years - the initial dose of 2.5-3 mg 2 times a day, if necessary, gradually increase the dose to 5 mg 2-3 times a day. At night enuresis, the last dose should be taken immediately before bedtime.

Side effect

• dry mouth;
• nausea;
• constipation, diarrhea;
• discomfort in the abdominal area;
• headache;
• drowsiness;
• dizziness;
• decreased visual acuity;
• dry skin;
• tides (more often in children);
• difficulty urinating;
• retention of urine;
• arrhythmias.

Contraindications

• violation of the outflow of urine from the bladder, when precipitation of delayed urine is possible;
• intestinal obstruction;
• intestinal atony;
• severe ulcerative colitis;
• expansion of the colon;
• myasthenia gravis;
• glaucoma;
• lactation (breastfeeding);
• children under 5 years;
• hypersensitivity to oxybutynin.

Application in pregnancy and lactation

In pregnancy Driptan is used only on strict indications, when the expected benefit for the mother exceeds the potential risk to the fetus.

Oxibutinin is contraindicated for use during lactation (breast-feeding).

Use in children

Contraindicated in children under 5 years.

Application in elderly patients

Use with caution in elderly patients.

special instructions

With caution apply Driptan in elderly patients, with neurocirculatory dystonia, violations of liver or kidney function, thyrotoxicosis, arrhythmia, IHD, chronic heart failure, arterial hypertension, initial manifestations of benign prostatic hyperplasia, NNC, in patients with ileostomy, colostomy, and hernia of the esophagus of the diaphragm, accompanied by reflux esophagitis.

Impact on the ability to drive vehicles and manage mechanisms

They are used with caution in patients whose activity requires increased concentration of attention, high speed of psychomotor reactions.

Drug Interactions

When used simultaneously with drugs that have an anticholinergic effect, it can be amplified.

With simultaneous application of Itraconazole increases the concentration of oxybutynin in the blood plasma.

Drug analogues Driptan

Structural analogs for the active substance:

• Novitropane;
• Oxybutine;
• Cystrin.

Analogues on the curative effect (means for the treatment of urinary incontinence):

• Adenostop;
• Adiuretin;
• Amizole;
• Amirol;
• Anaphranil;
• Brusniver;
• Vesicar;
• Gopantam;
• Gutron;
• Detruzitol;
• Clominal;
• Librax;
• Mininin;
• Pantogam;
• Pantogam is an asset;
• Pantokaltsin;
• Pyramids;
• Raveron;
• Rolitan;
• Spazmeks;
• Triptysole;
• Urotol;
• Cystrin;
• Enablex;
• Estrokad.

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