Nystatin - instructions for use, analogs, reviews and release forms (tablets and suppositories (vaginal and rectal) 250 thousand units and 500 thousand units, ointment for external use) of the drug for treatment of thrush in adults, children and pregnancy
In this article, you can read the instructions for using the drug Nystatin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Nystatin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Nystatin in the presence of existing structural analogues.Use to treat and prevent candidiasis (thrush) in adults, children, as well as during pregnancy and lactation.
Nystatin - an antifungal agent from the group of polyenes. By binding to sterols in the cell membrane of fungi, it breaks its permeability, which leads to the release of the main components of the cell. It has a fungistatic effect.
Active with yeast-like fungi of the genus Candida.
Pharmacokinetics
After ingestion, nystatin is poorly absorbed from the digestive tract. When topical application is not absorbed into the systemic circulation. Do not cumulate. It is excreted from the body with feces.
Indications
For tablets and ointments
- Candidiasis of the skin and mucous membranes;
- Candidiasis of internal organs;
- prevention of candidiasis with long-term antimicrobial therapy, especially in depleted and debilitated patients.
For vaginal suppositories
- vaginal candidiasis;
- prevention of fungal complications with local antimicrobial therapy.
For rectal suppositories
- candidiasis of the lower intestine;
- prevention of fungal lesions in pre- and postoperative periods.
Forms of release
Tablets coated with 250,000 units and 500,000 units.
Candles vaginal 250000 ED and 500000 units.
Candles for rectal use 250,000 units and 500,000 units.
Ointment for external use.
Instructions for use and dosing regimen
In the treatment of candidiasis of internal organs Nystatin is prescribed inside regardless of food intake.
Adults appoint 500 000 units 4-8 times a day.
In generalized candidiasis, up to 6,000,000 units per day is prescribed.
Children aged 1-3 years are prescribed 250 000 ED 3-4 times a day, at the age of over 3 years - 250 000-500 000 units 4 times a day. Duration of treatment is 10-14 days. If necessary, repeat the treatment in a week.
In the treatment of candidiasis of the skin and mucous membranes, the ointment is applied a thin layer on the affected areas 2 times a day, daily for 7-10 days. The use of the ointment can be combined with taking Nystatin by mouth.
Vaginal suppositories are inserted into the vagina after hygienic procedures 1 candle 2 times a day (morning and evening). The course of treatment is 10-14 days.
Rectal suppositories are injected deep into the rectum 1 candle 2 times a day (morning and evening). The course of treatment is 10-14 days.
If necessary, repeat courses of treatment.
Side effect
- nausea, vomiting;
- diarrhea;
- itching;
- chills;
- temperature increase;
- there is a risk of spreading resistant forms of fungi, which requires the withdrawal of the drug.
Contraindications
- impaired liver function;
- pancreatitis;
- peptic ulcer of the stomach and duodenum;
- pregnancy;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
Nystatin is contraindicated in pregnancy and during breastfeeding.
special instructions
With the development of adverse reactions should reduce the dose or cancel the drug.
When menstruating, do not interrupt treatment with vaginal suppositories. In fungal diseases of the vagina, simultaneous treatment of the sexual partner is recommended. During the period of treatment, sexual contact should be avoided.
Drug Interactions
With the simultaneous use of nystatin and clotrimazole, the activity of the latter decreases.
Analogues of the drug Nystatin
Nystatin does not have structural analogs for the active substance.
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