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Riboxin - instructions for use, reviews, analogs and formulations (200 mg tablets, 200 mg capsules, injections injections) drugs for the treatment of myocardial infarction, hepatitis and other diseases in adults, children and pregnancy

Riboxin - instructions for use, reviews, analogs and formulations (200 mg tablets, 200 mg capsules, injections injections) drugs for the treatment of myocardial infarction, hepatitis and other diseases in adults, children and pregnancy

In this article, you can read the instructions for using the drug Riboxin. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Riboxin in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Riboxin analogs in the presence of existing structural analogues.Use for the treatment of myocardial infarction, hepatitis and other metabolic diseases in adults, children, as well as during pregnancy and lactation.

 

Riboxin - refers to the group of drugs that regulate metabolic processes. The drug is a precursor of the synthesis of purine nucleotides: adenosine triphosphate and guanosine triphosphate. The active substance of the drug is Inosine.

 

Has antihypoxic, metabolic and antiarrhythmic effect. Increases the energy balance of the myocardium, improves coronary circulation, prevents the consequences of intraoperative kidney ischemia. It takes a direct part in the exchange of glucose and promotes the activation of metabolism in conditions of hypoxia and in the absence of adenosine triphosphate.

 

Activates the metabolism of pyruvic acid to ensure a normal process of tissue respiration, and also promotes the activation of xanthine dehydrogenase. Stimulates the synthesis of nucleotides, enhances the activity of certain enzymes of the Krebs cycle. Penetrating into cells, increases the energy level, has a positive effect on the metabolic processes in the myocardium, increases the strength of the heart contractions and promotes more complete relaxation of the myocardium in diastole,as a result of which the shock volume of blood increases.

 

Reduces platelet aggregation, activates the regeneration of tissues (especially the myocardium and mucous membrane of the gastrointestinal tract.

 

Pharmacokinetics

 

It is well absorbed in the gastrointestinal tract. Metabolised in the liver with the formation of glucuronic acid and its subsequent oxidation. In a small amount is excreted by the kidneys.

 

Indications

  • IHD;
  • myocardial dystrophy;
  • condition after myocardial infarction;
  • congenital and acquired heart defects;
  • heart rhythm disturbances, especially with glycosidic intoxication;
  • myocarditis;
  • dystrophic changes of the myocardium after heavy physical exertion and transferred infectious diseases or due to endocrine disorders;
  • hepatitis;
  • cirrhosis of the liver;
  • fatty degeneration of the liver, incl. caused by alcohol or drugs;
  • prevention of leukopenia during radioactive irradiation;
  • operations on an isolated kidney (as a means of pharmacological protection in the temporary absence of circulation in the operated organ).

 

Forms of release

 

The tablets covered with a cover of 200 mg.

 

Capsules 200 mg.

 

Solution for intravenous administration (injections in ampoules for injection) 20 mg / ml.

 

Instructions for use and dosing regimen

 

Tablets, capsules

 

Assign adults inside, before eating.

 

The daily intake for oral administration is 0.6-2.4 g. In the first days of treatment, the daily dose is 0.6-0.8 g (200 mg 3-4 times a day). In case of good tolerance, the dose is increased (2-3 days) to 1.2 g (0.4 g 3 times a day), if necessary - up to 2.4 g per day.

 

The duration of the course is from 4 weeks to 1.5-3 months.

 

With urocoppororphy, the daily dose is 0.8 g (200 mg 4 times a day). The drug is taken daily for 1-3 months.

 

Ampoules

 

When administered, the initial daily dose is 600-800 mg, then the dose is gradually increased to 2.4 g per day in 3-4 doses.

 

With intravenous (jet or drip in the form of a dropper), the initial dose is 200 mg once a day, then the dose is increased to 400 mg 1-2 times a day.

 

The duration of the course treatment is set individually.

 

Side effect

  • allergic reactions in the form of urticaria, skin itching, skin hyperemia (drug withdrawal required);
  • increased concentration of uric acid in the blood and exacerbation of gout (with prolonged use).

 

Contraindications

  • hypersensitivity to the drug;
  • gout;
  • hyperuricemia;
  • children under 3 years;
  • fructose intolerance and glucose / galactose absorption disorder or sugarase / isomaltase deficiency.

 

Application in pregnancy and lactation

 

The safety of the drug Riboxin during pregnancy and lactation is not established. Riboxin is contraindicated during pregnancy. For the duration of treatment with Riboxin, breastfeeding should be stopped.

 

Use in children

 

Contraindicated in children under 3 years.

 

special instructions

 

During the treatment with Riboxin, the concentration of uric acid in the blood and urine should be monitored.

 

Information for patients with diabetes: 1 tablet of the drug corresponds to 0.00641 units of bread.

 

Does not affect the ability to drive vehicles and manage mechanisms that require increased concentration.

 

Drug Interactions

 

Immunosuppressants (azathioprine, antilympholine, cyclosporine, thymodepressin, etc.) with simultaneous use reduce the effectiveness of Riboxin.

 

Analogues of the drug Riboxin

 

Structural analogs for the active substance:

  • Inosie-F;
  • Inosine;
  • Inosine-Eskom;
  • Riboxin bufus;
  • Riboxin-Vial;
  • Riboxin-LexT;
  • Riboxin-Ferein;
  • Riboxin injection 2%;
  • Ribonosine.

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Reviews (46):
Guests
chaclun
Riboxin pills were prescribed to me by my former classmate, and now a respected doctor in the city, when I turned to him with heart problems. It feels like my work has exhausted me and dried it, and my heart has tumbled like a broken engine of a driindul. So, rehabilitation was urgently needed and it came in the form of Mildronate and Riboxin. What is worth noting after the course of treatment. Got in weight - three kilograms for sure, maybe because of the pills, or maybe because he decided to take a timeout and get enough sleep,with the heart of problems also did not become, now it knocks exactly, and does not give in a throat as before, so could not fall asleep.
Guests
Oksana
Riboxin is a fairly reliable and effective drug that my mother took for heart problems. Her heart rhythm disturbances were observed, the medicine after a long period of time took off the unpleasant symptoms and became lighter. The only thing that she constantly had to check the blood and urine for the concentration of uric acid.
Guests
Ksenia
Is it possible to squeeze reboxin?
Administrators
admin
KseniaAs a concomitant component of treatment (as a metabolic means, to improve the effectiveness of treatment of patients with lupus carditis and other cardiac dystrophies) Riboxin can be used in the case of lupus erythematosus.
Guests
Galina
It helps, but it seems I'm gaining weight - maybe it's a coincidence.
Administrators
admin
GalinaIt is possible that because of the drug, it is still a metabolite in its essence, and the drugs of this group can give an increase in weight.
Guests
Valentina
Very good drug. Ten years ago in a sanatorium in Kislovodsk, the doctor recommended intravenous Riboxin intravenously in the spring and autumn. I follow the advice and is very grateful to him, tk. the result is excellent. The weight is not affected.
Guests
valentines
A wonderful product, it helps a lot.
Guests
vladimir
At me at change of weather of a problem with the complicated breathing, feeling of squeezing of a thorax. About 10 years ago I went to a doctor - it's useless. The neighbor advised Riboxin, tablets. After taking the pack of pills completely gone. And did not bother until recently. Now I've had a few packs of pills - it does not help!
Visitors
Vera VV
I was diagnosed with ventricular extrasystole. Has drunk pananginum, does not help or assist. Propanorm only relieves symptoms.Whether it is possible to be treated Riboxinum?
Administrators
admin
Vera VVAnd why should Riboxin help? You need to take all the tests (blood, biochemistry, ultrasound of the heart and kidneys, ultrasound of the vessels of the neck and legs, electrocardiogram) and after consulting with the cardiologist. Perhaps he will recommend daily monitoring of the ECG if the extrasystoles are rare and not fixed on the usual ECG. You yourself can not adequately treat such symptoms.
Visitors
Vera VV
All ultrasound and blood tests are within normal limits. Daily monitoring showed extrasystole. The trouble is that I was not prescribed treatment, only withdrawal of symptoms by propanorm. And somehow very long time from an arrhythmia to me the riboxin helped or assisted, and many years I did not recollect about her. Or is it just an accident?
Administrators
admin
Vera VV, Single extrasystole at 24-hour monitoring? Everything is right for you then appointed. There is nothing more to look for from drugs, and this is not a sentence with which it is impossible to live.
Visitors
Vera VV
It is written: "A single gastric es of type 1 in total - 221 (221 wakefulness), single supraventricular es only 23 (15 wakeful)." It's hard for me, even dark in my eyes sometimes.
Administrators
admin
Vera VVWith such monitoring data it is necessary that you be referred to a cardiologist. The therapist does not have the right to appoint something here, it's not his competence, the more you have manifestations of rhythm disturbances and the functions of the heart muscle.
Guests
Maric
I have a child of 13 years. And at the training camp (she is an athlete), her trainer is given a riboxin. I want to know whether it can be used for children? and how many per day?
Administrators
admin
Maric, Riboxin can be used for medicinal purposes for children over 3 years of age. Sports medicine is a slightly different field of activity. I perceive it more as mobilizing for the athlete's organism before and during the competition. Eligibility for the use of this drug for sporting purposes, including that of children, lies entirely with sports physicians.They use it in profile medicine, most likely for a set of muscle mass, increasing endurance in athletes.
Visitors
tandem
The doctor prescribed a 4-month-old grand daughter of riboxin and Actovegin. Can I use a liquid form instead of tablets?
Administrators
admin
tandem, I do not understand how doctors can prescribe tablets coated with children, if they are not intended for this age group. To separate such tablets is physically impossible, can thus mask the placebo effect (primarily for the parents of such children). So only injection forms are shown to such small children as your granddaughter.

Although it is worth noting, the fact of the effectiveness of Riboxin use in children has not yet been confirmed by anyone, that is, no clinical studies and evidence (tested in large groups of patients) that this drug has a positive effect in treatment, as well as no reports of harm to children from the use of this drug. Similarly, this applies to Actovegin.So here everything is up to the discretion of the doctor. I try not to experiment on my children, but I need to know the situation and sometimes this risk is justified if there is nothing to replace the medicine.
Visitors
tandem
Can I take the injectable form inside? How to calculate the dosage for 8 kg of weight? We took 1/4 tablet.
Administrators
admin
tandemInjectable forms serve for injection. All the rest is a balancing act, which is not a fact that will bring the desired result. It is better to dissolve the right amount of tablets in water. Although these appointments for a quarter of tablets are generally something of shamanism, because it is often impossible to adequately divide the tablet into 4 parts (the dividing risk is only in half, but not two risks for dividing into 4 parts), and Riboxin tablets also Covered with a coating that plays a role in transporting the active substance of the drug to the site of action. It seems to me that your doctor is doing a placebo for the parents of a sick child or that they are untied, such dosages seem to be weak for treatment.The truth and the diagnosis I have not heard, but it seems like that.
Visitors
Irina S
I was diagnosed with hypertension of 1 degree. My pressure before the illness was 110 now, 135, sometimes higher, my heart began to crush. This year she underwent an ENT surgery, there was a complication of great blood loss, lost weight. Will the course of taking riboxin help me to put the pressure back to normal? The therapist advised bisoprolol, but you do not want to drink it for life.
Administrators
admin
Irina S, First you need to be examined (tests, ECG, ultrasound of the heart and possibly vessels according to the indications), and then consult a cardiologist and neurologist (because the pain in the heart can be associated with the development of osteochondrosis of the spine). The pressure of 135 can still be taken as the norm, but if it periodically rises above 140, then it is already hypertension, although the initial stage and shows a constant intake of small doses of antihypertensive drugs. More questions are caused by constrictive pain in the region of the heart, this may be a harbinger of ischemia and this is already very dangerous.So you need to be examined and to the diagnostician. Riboxin is not worth taking.
Guests
Suzanne
Riboxin was prescribed intravenously, during the injection a very strong reaction to the drug: pain, numbness of the hand, burning and tingling, it is very difficult to tolerate: (The nurse says that bad veins.
Guests
Irina
I have IHD. A 2-chamber pacemaker with a heart rate of 60 beats / min is installed, Bradycardia and weak sinus node syndrome. IV infusions with Riboxin were given intravenously every other day. Pain after the droppers began. Pulls the veins from under the knee to the hip.
Guests
Marina Kr.
A wonderful drug! I was appointed by a doctor, tk. on a background of an autoimmune thyroiditis there was a cardiodystrophy (the electrocardiogram has shown). Everything passed and the pulse became normal (there was a tachycardia). Then a few years later, my heart began to ache again at night and the bradycardia began. Riboxin again helped. And recently I to myself have made an appointment, have spent on drink 2 packings of a riboxinum. I just remembered that he had not drunk for years. Also has noticed, that there was a dyspnea which attacks me sometimes and excruciates for some weeks, and it is not connected neither with respiratory organs, nor with thyroid, so doctors have told.And from what shortness of breath no one knows! And now she drank, so to speak for prophylaxis and dyspnea, imperceptibly left. I can also add that my mother lived for many years on riboksin and pananginum, and the arrhythmia of the heart actually passed! It's true now in the 88 years she went to a depression. So, I do not react to the doctors' comments about riboxin as a dummy. By the way, the doctor-therapist who appointed me this drug for the first time, was a doctor from God, knowing, experienced and not indifferent!
Visitors
surp
Is it possible to take Riboxin as a preventive agent for chronic atrophic gastritis and atrophic condition of the duodenum, if there is a large loss of weight. Thank you in advance.
Administrators
admin
surp, Riboxin - a drug in which a set of muscle mass is more a side effect and not a fact that you will manifest it. With gastritis, there should be no loss of body mass, atrophy of the duodenum may reduce absorption, but for diffodiagnosis it is necessary to make an analysis of the stool and determine the degree of digestibility of food in the gastrointestinal tract.It is also necessary to check the digestive glands (liver, pancreas) and exclude oncology (start diagnostics with ultrasound of the abdominal cavity and biochemical blood test).
Guests
Valentine.
When my sleep is disturbed, I take riboxin, it helps perfectly.
Visitors
shamray_u
Hello, the child was given a blood test for 4 years, the child had a CR 40.23 increase in creatine kinase, the result was a sinus rhythm, a heart rate of 12-98 Udine, a slight sinus arrhythmia, an electric vertical, a repolarization of the ventricles, a juvenile inversion of the T wave in the right thoracic leads. DS Postinfection cardiopathy. The doctor prescribed Riboxin 1/4 tablet 3 times a day for 20 days and magnesium B6 for 1 ampoule 2 times a day for 20 days, taken concomitantly with riboxin. And in the annotation to the drug write that its riboksin can not be taken simultaneously with vitamins, tell me, please, how should we be? Can I drink a magnesium after riboxin?
Administrators
admin
shamray_u, I do not know where you read about vitamins. Looked in the two reference books, including the active ingredient inosine. Nowhere is there anything about banning the joint use of Riboxin and vitamins. So take together (this means first Riboxin, and 15-30 minutes after Magne B6), as the doctor advised. There are no special prohibitions in this scheme, but cardiopathy is serious. Watch for any infections in your child and treat them in a timely manner.
Guests
Galina
In September 2015 I felt very bad, so bad that I could not even wash the dishes. Water with me river, weakness, shortness of breath. Crawled into the clinic. I did not get a reception - it was Friday, the doctor ran to the conference, but gave me a direction on the ECG. The procedure was carried out by a young m / s. The ECG showed that I have some abnormalities and I need to see a doctor urgently. But the doctor was not there and I crawled home. I opened the card, found the record of a cardiologist in 2007, and found that I was prescribed riboxin. She looked in the medicine cabinet, found an old blister of riboxin, looked in the instructions how to drink and drank these 10 tablets. And for three days come to life! (Even from old tablets).Then I bought a new one, but in the future, my blood pressure started to increase, and I stopped drinking it. The drug is wonderful!
Guests
alcoholic
Hello. I'm a beer alcoholic. The experience of drinking beer is about 10 years. Last time sometimes there are attacks of an extrasystole. Terribly it becomes for the life. I'm 31, even a week of abstinence does not help to eliminate extrasystoles. Especially arrhythmia occurs with physical activity. It seems that soon to me - to the next world: (Maybe Riboxin will help? Also I want to quit with alcohol once and for all, but it does not work yet.) Scots in the eyes began to appear, what to do? If I stop using alcohol, what are my chances?
Administrators
admin
alcoholic, You understand that with such problems at a young age you definitely go to the doctor for examinations and taking tests. Without this, a diagnosis will not be made and a normal treatment will not be prescribed. It's like doing nothing and waiting for something. It was necessary to throw alcohol yesterday, and further chances can be assessed only after assessing the functioning of the internal organs, it will be difficult to make one symptom.
Guests
M
How often can I do Riboxin intravenously?
Administrators
admin
M, 2 times a year can be repeated exactly. If more often - this requires the reasons from the patient's health.
Guests
Khalid
Is it possible to drive riboksin complex with cocarboxylase?
Administrators
admin
Khalid, Not prohibited. According to the instruction of negative side effects with the joint use of Riboxin and Cocarboxylase should not be. Only in one dropper these medicines are better not to mix, although there is no direct prohibition.
Guests
Gulimhan
You can use Riboxin in diabetes?
Administrators
admin
GulimhanUse Riboxin in diabetes mellitus is acceptable. Just keep in mind that it contains carbohydrates as fillers and the translation into grain units is in the instructions.
Guests
Tatyana Korzh
On the basis of nervous high stress, I was prescribed Riboxin with ascorbic and, of course, cerucal, as in the mornings I felt sick and vomited. But something already on the second day of treatment, I began to be sausage is not childish.
Guests
Olga
Tell me, please, how often do I have to take Riboxin? Thank you.
Administrators
admin
OlgaWhen no diagnosis is given or the case history is not described in detail, there can be only one answer - as recommended by the attending physician.
Guests
Olga
Good afternoon. My daughter has 14 years of mitral valve prolapse. In physical culture, when jumping rope, she had a pain in her heart. We went to the pediatrician - we were prescribed Asparks and Riboxin, should this be taken? Thank you.
Administrators
admin
Olga, Radically to struggle with prolapse it is possible only surgical operation if it is shown to the patient. In other respects, non-specific treatment is used - sedatives with severe stress, balneotherapy and spa treatment.In respect of your daughter recommended dosage physical activity is not in the general group, and in the group of therapeutic physical education, that is, with restrictions on the maximum workload, for such limitations, the doctor must also write out an order to the school.
Guests
Igor Chernyaev
There was an arrhythmia. A friend advised Riboxin. After a month of reception, the heart beats like a metronome. It was 15 years ago, until now everything is fine. I am now 55 years old. My wife had the same crap, also got rid of Riboxin. So tablets are checked for themselves and, importantly, - inexpensive.

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