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Wilprafen - instructions for use, reviews, analogs and forms of release (tablets 500 mg and 1000 mg of solute) for the treatment of ureaplasmosis, chlamydia and other infections in adults, children and pregnancy »Page 3

Wilprafen - instructions for use, reviews, analogs and forms of release (tablets 500 mg and 1000 mg of solute) for the treatment of ureaplasmosis, chlamydia and other infections in adults, children and pregnancy

In this article, you can read the instructions for using the drug Wilprafen. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Vilprafen in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Wilprafen in the presence of existing structural analogues. Use for the treatment of ureaplasmosis, chlamydia, bronchitis, pneumonia and other infections in adults, children, as well as during pregnancy and lactation.

 

Wilprafen - antibacterial drug from the group of macrolides. The mechanism of action is associated with a violation of protein synthesis in the microbial cell due to reversible binding to the 50S subunit of the ribosome. In therapeutic concentrations, as a rule, has a bacteriostatic effect, slowing the growth and multiplication of bacteria. When creating high concentrations in the focus of inflammation, a bactericidal effect is possible.

 

Josamycin (the active substance of the drug Vilprrafen) is active against Gram-positive and Gram-negative bacteria.

 

As a rule, it is not active against enterobacteria, therefore it negatively affects the microflora of the digestive tract. In some cases, it remains active in the resistance to Erythromycin and other 14- and 15-membered macrolides (streptococci, staphylococci). Resistance to Josamycin is less common than to 14- and 15-membered macrolides.

 

Pharmacokinetics

 

After ingestion, Vilprafen is rapidly absorbed from the digestive tract. Eating does not affect bioavailability. Josamycin is well distributed in organs and tissues (with the exception of the brain), creating concentrations exceeding the plasma concentration and remaining at the therapeutic level for a long time.Especially high concentrations of josamycin create in the lungs, tonsils, saliva, sweat and tear fluid. The concentration in the sputum exceeds the concentration in the plasma by 8-9 times. Passes the placental barrier, is secreted into breast milk. It is excreted mainly with bile, excretion in the urine does not exceed 10%.

 

Indications

 

Infectious-inflammatory diseases caused by microorganisms sensitive to the preparation:

  • upper respiratory tract infection and ENT organs (pharyngitis, tonsillitis, paratonzillitis, laryngitis, otitis media, sinusitis);
  • diphtheria (in addition to treatment with diphtheria antitoxin);
  • scarlet fever (with hypersensitivity to penicillin);
  • infection of the lower respiratory tract (acute bronchitis, exacerbation of chronic bronchitis, community-acquired pneumonia, including caused by atypical pathogens);
  • whooping cough;
  • psittacosis;
  • infection of the oral cavity (gingivitis, pericoronitis, periodontitis, alveolitis, alveolar abscess);
  • infection of the eyes (blepharitis, dacryocystitis);
  • infections of the skin and soft tissues (folliculitis, furuncle, furunculosis, abscess, acne, lymphangitis, lymphadenitis, phlegmon, panaritium, wounds / incl.postoperative / and burn infections);
  • anthrax;
  • erysipelas (with hypersensitivity to penicillin);
  • urinary tract infection and genital tract (urethritis, cervicitis, epididymitis, prostatitis caused by chlamydia and / or mycoplasmas);
  • venereal lymphogranuloma;
  • gonorrhea, syphilis (with hypersensitivity to penicillin);
  • Gastrointestinal diseases associated with Helicobacter pylori (including gastric ulcer and duodenal ulcer, chronic gastritis).

 

Forms of release

 

Tablets 500 mg and 1000 mg (Wilprafen Solutab).

 

Instructions for use and dosage

 

The recommended daily dose of the drug for adults and adolescents over the age of 14 years is 1-2 g in 2-3 doses. If necessary, the dose may be increased to 3 g per day.

 

Children aged 1 year have an average body weight of 10 kg.

 

The daily dose for children with a body weight of at least 10 kg is prescribed based on a calculation of 40-50 mg / kg body weight daily, divided into 2-3 sessions: children with a body weight of 10-20 kg are prescribed 250-500 mg (1 / 4-1 / 2 tablets dissolved in water) 2 times a day, children with a body weight of 20-40 kg prescribed 500-1000 mg (1 / 2-1 tablets dissolved in water) 2 times a day, children with weight body more than 40 kg - 1000 mg (1 tablet) 2 times a day.

 

Usually, the duration of treatment is determined by the doctor and is from 5 to 21 days, depending on the nature and severity of the infection. In accordance with the recommendations of the WHO, the duration of treatment of streptococcal tonsillitis should be at least 10 days.

 

In the schemes of anti-Helicobacter therapy Wilprafen is prescribed in a dose of 1 g 2 times a day for 7-14 days in combination with other drugs in their standard doses:

  • famotidine 40 mg per day or ranitidine 150 mg twice daily + josamycin 1 g 2 times a day + metronidazole 500 mg 2 times a day;
  • omeprazole 20 mg (or lansoprazole 30 mg, or pantoprazole 40 mg, or esomeprazole 20 mg, or rabeprazole 20 mg) 2 times a day + amoxicillin 1 g 2 times a day + josamycin 1 g 2 times a day;
  • omeprazole 20 mg (or lansoprazole 30 mg or pantoprazole 40 mg or esomeprazole 20 mg or rabeprazole 20 mg) twice a day + amoxicillin 1 g 2 times a day + josamycin 1 g 2 times a day + bismuth tricalium dicitrate 240 mg 2 times a day;
  • famotidine 40 mg per day + furazolidone 100 mg twice daily + jozamycin 1 g 2 times a day + bismuth tricalium dicitrate 240 mg 2 times a day).

 

In the presence of atrophy of the gastric mucosa with achlorhydria, confirmed at pH-metry: Amoxicillin 1 g 2 times a day + josamycin 1 g 2 times a day + bismuth tricalium dicitrate 240 mg 2 times a day.

 

For common and globular acne, it is recommended that Vildrafen be administered at a dose of 500 mg twice daily for the first 2-4 weeks, then 500 mg of josamycin once a day as maintenance treatment for 8 weeks.

 

Vilprafen Solutab tablets can be taken in various ways: the tablet can be swallowed whole, washed down with water or beforehand, before taking it, dissolved in water. Tablets should be dissolved in at least 20 ml of water. Before the reception, the resulting suspension should be thoroughly mixed.

 

When taking Wilprafen, it should be borne in mind that if one dose is missed, the dose of the drug should be taken immediately. However, if it's time to take the next dose, you should not take the missed dose, you need to return to the usual treatment regimen. Do not take twice the dose. A break in treatment or premature discontinuation of the drug reduces the likelihood of treatment success.

 

Side effect

  • discomfort in the stomach;
  • nausea;
  • discomfort in the abdomen;
  • vomiting;
  • diarrhea, constipation;
  • stomatitis;
  • decreased appetite;
  • pseudomembranous colitis;
  • hives;
  • angioedema;
  • anaphylactoid reaction;
  • bullous dermatitis;
  • multi-form exudative erythema (including Stephen-Johnson syndrome);
  • jaundice;
  • dose-dependent transient hearing impairment;
  • purpura.

 

Contraindications

  • severe violations of liver function;
  • children with body weight less than 10 kg;
  • hypersensitivity to the components of the drug;
  • increased sensitivity to antibiotics of macrolides.

 

Application in pregnancy and lactation

 

It is allowed to use during pregnancy and during breastfeeding after a medical evaluation of the benefit or risk.

 

The WHO European Office recommends Wilprafen as the drug of choice in the treatment of chlamydial infection in pregnant women.

 

special instructions

 

In the case of persistent severe diarrhea, one should keep in mind the possibility of developing a pseudomembranous colitis dangerous for life against the background of josamycin.

 

In patients with renal insufficiency treatment should be conducted taking into account the results of appropriate laboratory tests (determination of the clearance of endogenous creatinine).

 

Consideration should be given to the possibility of cross-resistance to various antibiotics from the macrolide group (microorganisms resistant to treatment with antibiotic related chemical structures may also be resistant to josamycin).

 

Drug Interactions

 

Because bacteriostatic antibiotics in vitro can reduce the antimicrobial effect of bactericidal antibiotics, their joint use should be avoided. Vilprafen should not be administered together with lincosamides. possibly a mutual reduction in their effectiveness.

 

Some representatives of the macrolide group slow down the elimination of xanthines (theophylline), which can lead to the appearance of signs of intoxication. Clinical and experimental studies indicate that josamycin has less effect on the elimination of theophylline than other macrolides.

 

With the joint appointment of Vilprafen and antihistamines containing terfenadine or astemizole, the risk of life-threatening arrhythmias may increase.

 

There are some reports of increased vasoconstriction after the joint administration of ergot alkaloids and antibiotics from the group of macrolides, incl. Single observation on the background of josamycin.

 

The joint administration of josamycin and cyclosporine can cause an increase in the level of cyclosporine in the blood plasma and increase the risk of nephrotoxicity.The concentration of cyclosporine in the plasma should be monitored regularly.

 

With the joint administration of josamycin and digoxin, an increase in the level of the latter in the blood plasma is possible.

 

Analogues of the drug Vilprafen

 

Structural analogs for the active substance:

  • Wilprafen solute.

Similar medicines:

Other medicines:
Reviews (271):
Visitors
Natalya78
In the treatment of dry cough, mycoplasma was found pneumatik. Have appointed or nominated 10 days to drink vilprafen. The cough was gone. Have appointed or nominated 4 more days, did not spend on drink. After 5 days I cough again. Can I drink another 4 days after the break?
Administrators
admin
Natalya78, Have a drink better Ambroxol, ATSTS, Bromheksin or any other expectorant. After a break in treatment, an antibiotic of another group is prescribed, and more often these drugs are prescribed to eliminate the residual manifestations of the disease. The body will fight the bacterium itself, if you only have a small cough and no more symptoms. And next time, strictly observe the prescriptions of the doctor or look for the source of your infection in the near circle and strengthen your own immunity.
Guests
Irina
Hello. Tell me, please, is it possible to take vilprafen with karsilom and cholagogue?
Administrators
admin
Irina, It is not prohibited. But I would take Karsil and choleretic after the termination of the course of taking Vilprrafen (if this is not a compound treatment course), because changing the hepatic metabolism we can influence the absorption and accelerated removal of the drug from the body. It will be very difficult to prescribe an adequate dosage of antibiotic, which will support the antibacterial level of the drug in the blood.
Visitors
zaaya
Hello! We with the husband for a long time plan pregnancy, but at us it turns out nothing, send on doctors. To me the doctor has appointed or nominated to hand over a femoflor and to the husband spermogrammu. All have handed over, at me anaerobic dysbiosis, a ureaplasmosis, a mycoplasmosis is found out. The doctor said there is nothing wrong with this, and does not affect pregnancy in any way. Has written out Klindatsin B prolong 3 syringes and vilprafen 3 times a day 7 days. Strict barrier contraception. At the husband on spermogramm the gynecologist has looked or seen and has sent it or him to the doctor and has told or said, that a problem in it or him, but when we have come to the urologist he has told or said a semen ideal. Although according to the graph of the WHO standard there are points of deviation such as: a viscosity of 5 cm, there is no complete dilution, aggregation of sperm +, the question is how should we be? Go to another doctor? Because in the competence of my doctor I'm 100% sure, she could not be mistaken, sending him to the doctor. And why barrier prevention if no one has prescribed any treatment for him? Thank you for attention.
Administrators
admin
zaaya, Many have written, but the problem is complex, therefore, I will answer that which is clearly understandable from the question.

A husband needs to be examined for sexually transmitted diseases, that is, he can not avoid putting a smear, plus there is agglutination of spermatozoa, so I would give him an examination for sugar, including latent glucose. According to the results of the research, it will be clear to him that antibiotic treatment as well as to you or barrier barrier will be enough, and without any examination and treatment of a partner in such contraception, there is really no benefit.

And the semen needs to be examined by an adequate specialist, if there are ECO centers in your city, it is better for the reproductive expert there, they understand more in these analyzes and know what parameters are necessary for conception and which are secondary. And since the viscosity is large, plus agglutination - it is necessary to treat.

And I would not be so sure in my gynecologist, you have two infectious agents in the analyzes and no problems because of this with pregnancy, this is doubtful.

In general, be treated, be surveyed further and successes to you.
Visitors
zaaya
I do not understand what kind of doctors we have a nightmare. I knew that the urologist just waved us off, because he worked the last day before vacation.At the expense of myself I can say, thanks for such a quick and specific answer.
Visitors
Katya Katya
Good afternoon! At me are found out: gardnerella, a ureaplasma and VPCH 18. The doctor has registered suppositories Terzhinan, vitamins Rejtoil and Vilprafen 500 on 1 tablet once a day (course of treatment - 10 days). I have no complaints about candles and vitamins))) but on antibiotic, I doubt ... The instructions indicate the period of antibiotic action - 12 hours, was it wise to prescribe one pill a day? And can I replace Wilprafen with Macropen and take it according to the instructions?
Administrators
admin
Katya KatyaIn regard to the infections you have found, I would advise to leave Wilprafen and not replace it with Macropen, to which many infections have already developed resistance. And you need to take an antibiotic correctly 2 or even 3 times a day. And in your case it turns out and the dosage is weak (500 mg to adult patients no one appoints, such doses from 1 gram per day start) and the reception mode is incorrect. It would be necessary to clarify once again the treatment scheme of the attending physician.
Guests
Guzel
Good afternoon. I am ill for the second week, the temperature is 38 ° C in the evenings. The therapist has registered vilprafen 1000, but since. I nursing mother said to express milk before each feeding. Tell me please, is it safe for the baby (3 months)?
Administrators
admin
GuzelDuring feeding, the antibiotic Vilprafen is the drug of choice and, according to strict indications, its use in nursing mothers is permissible. To express and emit breast milk when taking this antibiotic is not needed, but the child's condition in such treatment should be monitored and, when changes occur, notify the attending physician about it, to correct the treatment.
Visitors
Ramina
Hello. I was diagnosed with gonorrhea, given a complex for infection, among them only gonorrhea, my friend discovered gonorrhea and chlamydia. The doctor prescribed this treatment 1x Ceftriaxone + Wilprafen 1 tablet three times a day, 7 days course. After 3 days for the control check.Question: Is the treatment right? Are antifungal drugs prescribed during treatment with Vilprafen? Thank you in advance.
Administrators
admin
RaminaIf you have a clamidiosis in your sexual partner, then you have it, just the causative agent did not get into the material under investigation. According to the treatment, everything is prescribed correctly, two antibiotics from different groups (Ceftriaxone once), considering two infections it is necessary to apply a massive blow to the pathogens, so that the diseases do not go into chronic form.

I think Vilprafen's course is only too small in duration, I would give a minimum of 10 days, not 7. I need antifungal drugs, best twice during the treatment, the last appointment after the course of antibiotic therapy.

It is also better to pass a control test later, for example, in two weeks. The point is that they will set the pathogen in 3 days (in case of ineffectiveness of the treatment) still need to prescribe other antibiotics and the tactics of the early control smear will not affect it in any way.
Visitors
Ramina
Good afternoon. Thank you for the answer. Advise, please, what antifungal agent to take? It's strange that the doctor did not appoint me, although it's not surprising, because when she prescribed the treatment she was guided by the book. Thank you in advance.
Administrators
admin
Ramina, You can take any remedy based on fluconazole (Diflucan, Fluconazole, Flucostat and many others), ketoconazole (ketoconazole), terbinafine (Terbizil, Terbinafine). I like the import Diflucan, one capsule can be taken in the middle of the antibiotic treatment course, the other one immediately after the course of therapy.
Visitors
Nika)))
Hello. I am treated for ureaplasma and mycoplasma. At the moment the treatment is coming to an end, there are 2 days left. The question interests, how much or as far as in your opinion an effective scheme or plan of treatment?
The first day in the evening on the eve - tinidazole 4 pcs. once. Next 5 days Ornidazole 2 tablets a day. Next 5 days Metronidazole 1 tablet 3 times a day. Further Vilprafen solutab 1000 for 3 tablets a day - 5 days ..
During the administration of Ornidazole and Metronidazole - Candles Genferon 500/2 times a day in the vagina for 10 days, i.e. only 20 candles.During the reception Vilprafena - candles Gexikon 2 times a day / 5 days, i.e. only 10 candles.
+ During treatment, injections of Cycloferon every other day.
And of course Karsil, Lineks, Flukostat / Fluconazole. And after treatment of the candle Bifidumbacterin.
Thanks for the answer.
Administrators
admin
Nika))), Slightly different than the one you already mentioned in the question to the drug Zitrolide, but the essence is the same. If you are cured, what's the point now in another scheme? Both are good. In general, before the start of antibiotic therapy, it would be good to determine the sensitivity of the planted pathogens to an antibiotic and to be treated sightingly, and not a finger to the sky. Antibiotics are now many and schemes can be written a lot.
Visitors
Nika)))
Thank you very much for the answer! wink
Guests
Magamadova Madina
At me one year ago all internal bodies have swelled up. I thought I would put a dropper and it will all go away. Earlier, too, it happened and I was saved by droppers ringer, pills and nyxes Essential, but this time the disease lasted as much as 7-8 months.Nothing, nothing helped. I was in the hospital, I was given about a hundred droppers, but the pain and nausea were as they were, and they stayed. I was discharged with a diagnosis of acute pancreatitis, hepatosis of the liver, cholecystitis, in addition to kt found an ovarian cyst. With this set, I left the hospital. As I said earlier, after the hospital, I took all the prescriptions of doctors, followed a diet, I lay in the day hospital, I was pricked with antibiotics, droppers were put, but the long-awaited recovery did not come. In addition, I left the hospital with a temperature of 37, and she stayed with me until my complete cure. And it came in 7 months. In a word, I brought all this list to tell you that after the prescription, which the wonderful person and professional of the business wrote to me, gastroenterologist Irina Valeryevna, where wilprafen 1000 was present, I felt better on the 5th day. I did not believe this miracle: I let go of the liver, stomach, pancreas, the temperature dropped, began to go through my eternal chill (all these months I was terribly cold, I threw off a kilogram of 12, most of my hair fell out, my stomach was swollen and even insignificant to him brought a hell of pain).And so it was hard for me to believe that my torment was over, that God had mercy on me and sent help in the person of Irina Valeryevna. Together with such drugs as Elton, Ursosan, Losse, rioflora, enterofuril suspension, ulkavis and our vilprafen disease released its iron fight. I, of course, try to follow a diet, although I admit there are inaccuracies, but today I can control my illness. It's impossible to cure my bunch of sores forever, but it's quite real to live until Allah calls to him. Wilprafen is an excellent product.
Visitors
Alexander Yu
Hello. Please answer my question. My throat was very bad and nothing else, went to Laura, diagnosed catarrhal angina, received a full course of treatment: rinse with chlorophyllipt, tonsilotrene, nimesil, zirtec, avamis spray, golaprop spray and antibiotics in the form of flemoxin solute and metrim with vitamin C + glucose. Five days passed the effect of zero. Having phoned him advised to address someone else, began to engage in self-treatment, i.e. soar his feet, rub and continue his treatment. However, after 3 days I was convinced of inefficiency.I went to another lor, a diagnosis of tonsillopharyngitis. She initially prescribed a local treatment, although her throat became less aching, but still hurt a little, i.e. the pain did not go to the end. Another 3 days passed, and again an antibiotic (Vilprafen 500) was prescribed for 1 tablet 3 times a day. I take it for the third day, the pain in my throat has gone, but it feels dry, I'm already worried about the treatment and hence the question is whether to replace wilprafen 500 by 1000 and on what day should the throat pass?
Administrators
admin
Alexander Yu, Given the previous treatment with Flemoxinum, 3 days of receiving Vilprafen should help to cope with any bacterial infection. I can assume either the viral nature of the disease - then the antiviral medication will help, or if the patient at the age can assume some form of atrophy, that is, atrophic pharyngitis, in which case the back wall of the pharynx should be oiled, inhaled, and antibiotics in this case will be are useless. But without an examination, it's probably impossible to predict anything remotely, although by description I would put on atrophic processes in the back wall of the pharynx.
Visitors
advert
Good afternoon. Literally a month and a half ago, itching and burning of the penis began. I thought it would pass, did not pass. I went to the venereologist, since we do not have a urologist. Has handed over the analysis of a smear from a urethra. The analysis came, the doctor said that I will have a urethritis (from where I can not understand, since I do not have a frequent sexual life, and consequently there was no sexual contact for a long time). He explained what could be due to a cold, and by that time I had been sick for a month already. After consultations he registered. Wilprafen 2 times a day for 5 days. Doxycycline 2 times a day for 5 days. Methyluracil suppository at night (was hemorrhoids, mb therefore appointed) Nystatin ointment was smeared on the foreskin. It took 5 days exactly, went and passed the tests. Dear tell me whether I recovered? The doctor says that everything is fine, I apply the screen from the tests with the results. Itching and burning have gone away, but there is some discomfort in the lower abdomen.
Links to the analysis, I'm sorry, but I do not know how to add pictures here. Thank you in advance :)
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Administrators
admin
advert, In some leukocyte laboratories the norm is up to 10 in the field of view, in some up to 5, therefore it is necessary to know the norms of your laboratory. Otherwise, cocci and other meager microflora may be present in the urethra, even intestinal sticks, especially if unprotected sex is practiced. In your situation, you need to deal with your doctor in person or wait and see for the presence / absence of symptoms of urethritis. By analysis I can assume the norm.
Visitors
Lisochka
Hello. Handed over the analyzes planned (dysplasia, postoperative control). They found out the bacterial flora, they sent it for sensitivity. On its own initiative, I submitted another PCR to the ureaplasma and chlamydia. Bac.posev revealed staphylococcus to an insignificant degree. But the PCR showed ureaplasma. The doctor prescribed the treatment of vilprafen solutab at 500 * 3 / 10d, junidox solute 100 * 3 / 7d, suppositories viferon 10d. me and my husband + me candles neo-pentotran forte 7d., and after me there are candles geneferon 10d. We drank wilprafen, junidox and my neo-pentotrans. On the sixth day, I had a rash on my face, then on my chest and neck. In another day all this became covered with abscesses.Tell me, is this a normal pobochka? I was told that this is similar to the development of staphylococcus aureus! How so? To the doctor to go there is no opportunity, NG at all)))
And more, do I need to apply further and geneferon in candles?
Visitors
Direktor2000
Hello. The girl found chlamydia and ureaplasma. The doctor appointed both:
Wilprafen 0,5 3 / day 21 days
Nystatin 4 r / day 21 days
Mycosyst 1 tab in the beginning after 3 days
Normobakt 2p / day 21 days
Genferon candle 2 p / day
After this course, 7 days, Trichopolum 2p / day.
There is no intolerance. I am being treated for the first time. Are not too many drugs? And not a long course? Do I need to send close relatives for examination with whom I contact each day?
Administrators
admin
Lisochka, There may be a side effect from the use of antibiotics, and maybe the gastrointestinal tract has failed after the load. Try to drink probiotics (Linex, Bifidumbacterin and others), and also include in the diet more fermented milk products (yogurt, yogurt). The course of treatment is completed, all the more serious you have already taken.
Administrators
admin
Direktor2000, Nystatin and Mikosist appoint together, I think unnecessarily, because the same type of medicine for the treatment of fungal infection against a background of massive antibiotic therapy and you can leave one thing (better Mycosyst), and the rest is an adequate course, given that ureaplasma is always difficult to treat and prolonged antibiotic therapy is justified. A month after the end of treatment, both sex partners need to re-take tests. In the treatment of relatives in the absence of sexual contact, there is no need.
Visitors
Ketevan
Hello. Carried out analyzes of PCR, found gardnerella vaginalis, candida albicans, ureaplasma species. The doctor prescribed vitprafen 500 mg 3 times a day for 10 days, trichopolum 2t 2 times a day for 10 days and candle clion 10 days, but after the monthly ones go. They did not go, and I decided to take the pills, on the 5th or 6th day of taking the pills, the menstruation went, I missed one day of the candle because of the strong current, and missed the vilprafen and trichopolum for 2 days, but not in a row, because it was very bad for these tablets. I completely drank my dose of pills, but with badges.Prompt please, treatment will give result if tablets 2 days, but not successively and one day of a candle have been passed or missed?
Visitors
olga alexandrovna
The son has radiographs - signs of bronchial (as it is written) changes, there is no cough, but the temperature is 37.2-37.3 for a week. According to the analysis of blood, the excess of the norm of monocytes (14.4%) and lymphocytes (42.4%). The rest is normal, the urine test is normal. The doctor prescribed vitprafen and zitrox 500 at the same time. I have doubts, is this correct, do you think, a respected site administrator?
Administrators
admin
Ketevan, Predicting is impossible, you will learn the result on repeated smears, which I recommend taking in a month after the end of the course of treatment. Sometimes, strict adherence to the dosing and receiving regimen does not allow all such infections to be cured immediately and other antibiotics must be repeated.
Administrators
admin
olga alexandrovna, Two antibiotics from one pharmacological group (in your case macrolides), no one appoints. Or it was suggested to choose Sitrox or Wilprafen, or the doctor is incompetent.
Guests
Victoria
She started taking pills and stiffness of the body part, inhibition, wringing her shoulders.
Guests
margarit
Before parting with her husband for good, had an intimate contact with him, after which I realized that there was treason. He swore like everyone else that there was nothing. Year he lived to himself quietly, as well as all men often do not bother anything there - just carry. ((I've been asking all year for all gynecologists that for strange transparent odorless discharge and all the gynecologists and even professors of gynecology (I'm observed for hyperplasia years 10 at them) repeated - there are no infections.While I did not pay the tests for 13-15 infections of all kinds of hidden ones, I found out a ureaplasma .. My husband then told me about the affair with the 25-year-old ... by phone.I am a chemist, I was not too lazy and passed the analysis on the sensitivity to antibiotics, and so there is no azit omitsin, nor anything usually prescribed in any way, but only Wilprafen and Doxycycline were effective, only 2. I drank Wilprafen 500 mg twice a day for 10 days and passed the tests faster, the PCR showed the presence of ureaplasmas, I was upset (((I decided then But just in case, I sowed the sowing on the ureaplasma, but it is not. I already did not take it several times.Conclusion: the drug is good, there was no side effects. Already and effectively treated the upper respiratory and medial, too)) PCR after the treatment of ureaplasma to take it is not in a hurry, there are fragments of ureaplasma dead still there))) Only Wilprafen. Other chimois can not be added at all, unless it is a bouquet with other dirty tricks.
Visitors
Minona
Hello. I'll start, perhaps, from the beginning. At the end of September she very badly caught cold, she did not go to the doctor, as she was on vacation, she was treated for herself for a month herself, squirted spray in her nose and took Ampicillin (I can not remember the dosage according to the instructions), for a couple of days in the morning my eyes watered. Until the end of October, there were still weak signs of a cold, but except chamomile with carmolis, nothing more drank. At the end of November, before treating erosion (I have it for more than 5 years), I was referred to an ELISA for infection, I passed it on 28.11. Since in our consultation this ELISA is done for 14 days, I was sent to the treatment of erosion without results, where the doctor limited only to the biopsy of the uterus (because erosion was old to exclude the presence of cancers), it was 29.11. And I registered this course:
Doxycycline for 1т 3р / д - 5 days
Metronidazole 0.25 to 1T 3p / d - 5days
Fluconazole 0.15 on the 3rd day of treatment
After that, Methyluracil by 1sv n / night - 10 days
I finished the tablets 10.12, the candles were 20.12, then I had a doctor's appointment, where she told me to give the PCR to HPV types 16 and 18 and prescribed treatment (about it below). In a day I received the results of 28.11 ELISA:
Chlamydia trachomatis IgA titer 8.1 (1:80)
Chlamydia trachomatis IgG titer 12.9 (> 1: 160)
Mycroplasma hominis IgA titer 0.1
Mycroplasma hominis IgG titer 0.0
Ureaplasma urealyticum IgA titer 0.2
Ureaplasma urealyticum IgG titer 0.0
Reception was only after NG, therefore I have decided to hand over PTSR and on a chlamydia. 06.01 Has handed over in Invitro the analysis PTSR on a chlamydia and VPCH, results both negative, my groom handed over in the same laboratory for a week before me, at it or him the result positive! Extraneous contacts are excluded, the last 4 months by coincidence of circumstances are constantly in sight of each other. After putting the tests on 10.01 I started the course, appointed at the last reception, namely:
Metronidazole 0.25 to 1т 3р / д - 7days
Terzhinan on 1t for the night - 10days
Panavir by 2pieces of 3p / d - 10days
Visitors
Minona
She finished the course on January 19, 30.01, she was at the doctor, she looked at the results of IFA and she said that the infection was fresh, and it is very strange that my partner had positive PCR (by the way, he had not shown any signs of chlamydia.)I told her that I was sick for a month and was sitting on antibiotics, and that once with an old partner I had signs of infection with chlamydia (pain in sex), then I had erosion, but then the pains passed and I did not feel anything did not treat, then I still had PCOS (on laparoscopy, could not solve PCOS or cyst), I also did not heal it yet. On the question whether it is possible that this was a relapse, she did not really answer, she said that maybe against the background of antibiotics so (which meant "so" I did not understand). Has told the groom to address to the urologist, and to me has appointed or nominated a course:
Wilprafen by 1t 3p / d - 10days
Metronidazole 0.25 to 1т 3р / д - 10 days
Fluconazole 0.15 on the 3rd and 5th day of treatment
Miramistin or Chlorhexidine syringe for the night - 10 days
Polizhinaks on 1sv n / night vaginally - 10days
Viferon 1mln / night rectally - 10 days
Wobenzym 2t 3p / d 28days

The questions are:
1) The dosage of Vilprrafen is not indicated in the prescription, Soluteb was given at the pharmacy. How to use? on 1000 3 r / d, or in the recipe all the same was meant Wilprafen 500, and to accept 1000 on 3p / d is dangerous and it is necessary on 1000 2р / д?
2) Both Wilprafen and Wobenzym should be taken 30 minutes before meals. Wobenzym wash down with water, it's understandable, but how to take Wilprafen (a whole 1000 I'm not likely to swallow, I'll have to make a suspension, written at least 20ml of water)so in what maximum amount can you dissolve it, and can this solution be washed down with Wobenzym? Or you need to drink for 40 minutes Wobenzym, and then after 10 minutes a suspension of 20ml, and can you wash it with water? Or drink them in a row? On the Internet, I did not find anything, as in the instructions.
3) Wobenzym is written from 3t for prophylaxis, for strengthening antibiotics 5t 3p / d, and I was prescribed only 2t 3d / d, is there any sense from such acceptance? Or is it to not burden the body?
4) Whether it will be necessary after 10 days of tablets to take Lactofiltrum, or from a dysbacteriosis will be Wobenzym?
5) How effective is this scheme of treatment for chlamydia, considering all the above, and what is the probability that this is not a new disease after all, but a relapse amid a monthly weakening of immunity and taking antibiotics? In this case, why is PCR negative? How likely is it that the antibiotic treatment affected the surge of antibodies, and the analysis was incorrectly done (possibly on HPV too, because the material was taken 1 time for both tests), given that my fiancé is positive and has good immunity , and he did not take any medications at all?

Forgive that so much, just to draw a conclusion as much as possible the information is not superfluous. And I just do not have anyone to turn to, the city we have a small, literate gynecologist is almost impossible to find, but in the current I'm not so sure.
Administrators
admin
Minona, The question is so extensive that it does not fit in the standard text field of the site or you did not finish it. Although I did not see the question specifically (you can specify in the comments later), I can say that you will not find the guilty in this situation if before the beginning of sexual activity with this partner you took both smears and they were clean then there would be food for thought, and so these infections can be inherited and lived for a long time, without thinking about the consequences, but the human factor in the form of external sexual relations has not been canceled. Treatment is shown to both of you if the infection is observed in one, most likely it will be in another partner. If your fiancé was giving a smear, then most likely they should have made an antibioticogram of the sown pathogens, then it is treated better with antibiotics that are sensitive to the pathogen,plus it is possible for women to add local and immune drugs (the same Terzhinan, Genferon, Panavir, Polyoxidonium and other drugs).
Administrators
admin
Minona, Here is the continuation of the question. I will answer questions on the points:
1) Wilprafen is most likely 500 mg. Because the maximum daily dosage of an antibiotic is 2 grams, you get 1.5 grams (although I would take 1000 mg and take 2 times a day).
2) Take 30 minutes before eating Wobenzyme in the form of a suspension (dissolving tablets in water), after 10 minutes you can take Wobenzyme, washing down with water. It is not recommended to mix different medications in the same treatment, although there is nothing to worry about from the momentary reception of Vobenzima and Vilprafen (this is in case the scheme can not be sustained or hurry somewhere), but I would not mix it.
3) It is better to take 3 tablets 3 times a day. There is nothing to load here, the enzyme systems, loaded with antibiotic, you only will say thanks for Wobenzym.
4) Lactofiltrum or any other bacterial preparation or probiotic will be acceptable after a massive course of antibiotic therapy.
5) As answered in the answer to your first question, what will it give you? If you want to blame your fiancé or yourself - this is no longer a medical issue, but a social one. Possible and the so-called relapse, but these infections do not have the concept of relapse, causative agents or are present in the body or they do not exist in principle. Therefore, treat together, give in a month control smears (you can additionally take immunology for chlamydia and HPV) and be healthy.
Visitors
Minona
Hello again. Thank you for providing answers. In the 5th question I wrote:
"How effective is this treatment for chlamydia, considering all the above, and what is the probability that this is not a new disease after all, but a relapse amid a monthly weakening of immunity and taking antibiotics? In that case, why is PCR negative? How likely is the antibiotic treatment affected a burst of antibodies, and an analysis was incorrectly done (possibly on HPV too, because the material I took was 1 time for both tests), given that my fiancé is positive, and his immunity is good, and he did not take any medication Posted in General? "
The goal is not so much for accusation as for understanding the situation as a whole, because my gynecologist says that the infection is fresh, I, considering all the above facts, believe that the exacerbation has passed into a hidden form, because such obvious signs (pains at the PA) as many years ago I never had any more. It is still not clear with the results of the tests: is it possible to determine by the number of antibodies at what stage of the infection the infection is fresh or not, and why was the PCR negative, is it possible that this was due to taking the first and second courses of drugs described above . Well, considering all the above, what is your probability of being cured by this scheme of drugs for one course (I mean the last assigned, where is Wilprafen and Wobenzym)?
Administrators
admin
MinonaA diagnostic test for sexually transmitted diseases is a smear with pathogens. The determination in the blood test is not a guaranteed prognostic criterion (with the exception of chlamydia, trachomatis can be determined by blood). Therefore, next time, take a smear plus an antibioticogram and do not have to be tricky.Old, new infection does not matter if they found pathogens to be treated. Do not want to re-infection - treat your sexual partner the same (except for vaginal suppositories, of course). And to predict something is now difficult. Infections have become evil, there are a bunch of drugs patients take and in control smears a month later still discover the pathogens, you have to change the scheme of therapy and treat again.
Visitors
Nazsaqyoon
Hello. In December, I had a miscarriage. To find out the reason the analysis has handed over, have found out a cytomegalovirus and a ureaplasma. The doctor prescribed the injections. Cicloferon 10 days alternate with Milgamma 5 days, Valtrex 2 times a day course 14 days, Vilprafen 500 mg solutab 2 times a day course 5 days. To the husband too. And even an additional hexon candles course 10 days. I'm interested in when you can pass repeated tests? I really want to get pregnant again)
Administrators
admin
Nazsaqyoon, A month after the end of the course of treatment, you can pass a control smear (including her husband) and if everything is purely planned for pregnancy.
Guests
Evgesha9393
Hello, tell me, please. The doctor prescribed vilprafen 3 times a day for 7 days, but one tablet is not enough. Can I not drink one tablet?
Administrators
admin
Evgesha9393, 1 tablet Wilprafen can not drink. I doubt that this will make the antibacterial effect worse or weaker.
Guests
Olga
Hello. I'm planning a pregnancy. One and a half month ago, for the first time in my life, condylomas came out, HPV was detected. Have appointed Isoprinosine + Genferon + Epigen. I see no effect, only new warts appear. Now the doctor on examination has told or said, that at me also herpes (too never in a life it or him was not), and has remembered still, that in the past to year in analyzes on IPPP at me the ureaplasma Parvumum is found out. That is, I gave all the infections last year several times, and no HPV, no herpes and nothing else, only the last time there was ureaplasma less than 10 to 4 degrees, so nothing was treated. But now the doctor remembered all this and appointed: Wilprafen + Valtrex for three months + Wobenzym for a month.And no planning for pregnancy before removing all infections.

Tell me, is this appointment adequate? And I now already know that HPV is not being treated, that ureaplasma in small credits does not threaten anything, but what about herpes, what if pregnancy suddenly happens?
Visitors
Olga 003
Hello. They could not tell me .... The doctor prescribed the antibiotic Wilprafen Solutab for 1 tablet 2 times a day (for 2 weeks, a strong cough and runny nose are excruciating). I read the instructions and in contraindications it is written that the drug can not be taken to people with severe impairment of liver function. And I have cirrhosis of the liver (nonalcoholic). The doctor knows this. Can I drink it? Or is it better to stop taking this antibiotic? Thank you.
Administrators
admin
Olga 003And what is the alternative? Alternatives to antibiotics in the prolonged course of an infectious bacterial process are not present. In your case, most likely, they chose less of two evils, so in general, such an appointment can be considered adequate.True, given the concomitant disease should have recommended any hepatoprotector to help the liver during the extra workload and to protect it (Essentiale, Ursosan, Ursofalk, Heptral and others).
Administrators
admin
Olga, Oral herpes (the one that can appear on the lips) does not bring any particular harm, but genital herpes before the planned pregnancy should be treated and controlled this process, because this type of herpes affects the development of the fetus.

Otherwise, some porridge, retake the panel on viruses and STDs again to remove existing issues and calm yourself and the doctor. If something is found, it is better to treat before pregnancy than in time.
Visitors
Osten
Hello. I was prescribed a course of the following drugs for 2 weeks:
1) Wilprafen
2) Wobenzym
3) Linex
And in parallel I have to drink from herpes acyclovir.
Today started drinking according to the instructions drunk Wobenzym 30 minutes before meals, acyclovir while eating, Wilprafen and Linex after a meal.
At me a question correctly I distributed them and whether it is possible to combine all these medicines simultaneously? I'm worried that this will be a big load on the body. recently the body is very weak and often there is an arrhythmia of the heart.
Administrators
admin
Osten, All the medicines indicated in the question are combined together with simultaneous admission. Distributed you treatment is normal. As for the indications and contra-indications of specific medications, including against the background of the course of concomitant diseases, it is better to contact the doctor in person, who has the opportunity to see what the patient was treated and how his medical history proceeds.

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