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Dexamethasone - instructions for use, reviews, analogs and forms of release (tablets 0.5 mg, injections in ampoules (solution for injection), drops ophthalmic ophthalmic) drugs for the treatment of inflammation in adults, children and pregnancy »Page 2

Dexamethasone - instructions for use, reviews, analogs and formulations (tablets 0.5 mg, injections in ampoules (solution for injections), drops ophthalmic ophthalmic) drugs for the treatment of inflammation in adults, children and pregnancy

In this article, you can read the instructions for using the drug Dexamethasone. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Dexamethasone in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Dexamethasone in the presence of existing structural analogues. Use for the treatment of inflammatory and systemic diseases, including the eyes, in adults, children, as well as during pregnancy and lactation.

 

Dexamethasone - synthetic glucocorticosteroid (GCS), methylated derivative of fluoride prednisolone. Has anti-inflammatory, antiallergic, immunosuppressive action, increases the sensitivity of beta-adrenoreceptors to endogenous catecholamines.

 

Interacts with specific cytoplasmic receptors (receptors for GCS are present in all tissues, especially in the liver), with the formation of a complex inducing the formation of proteins (including enzymes that regulate vital processes in cells.)

 

Protein metabolism: reduces the number of globulins in the plasma, increases the synthesis of albumins in the liver and kidneys (with increasing albumin / globulin ratio), reduces synthesis and enhances protein catabolism in muscle tissue.

 

Lipid metabolism: increases synthesis of higher fatty acids and triglycerides, redistributes fat (accumulation of fat occurs mainly in the area of ​​the shoulder girdle, face, abdomen), leads to the development of hypercholesterolemia.

 

Carbohydrate metabolism: increases the absorption of carbohydrates from the gastrointestinal tract; increases the activity of glucose-6-phosphatase (increased intakeglucose from the liver to the blood); increases the activity of phosphoenolpyruvate carboxylase and the synthesis of aminotransferases (activation of gluconeogenesis); promotes the development of hyperglycemia.

 

Water-electrolyte metabolism: retards Na + and water in the body, stimulates the excretion of K + (mineralocorticoid activity), reduces the absorption of Ca + from the gastrointestinal tract, reduces the mineralization of bone tissue.

 

The anti-inflammatory effect is associated with the suppression of the release of eosinophils and mast cells by inflammatory mediators; inducing the formation of lipocortins and reducing the number of mast cells that produce hyaluronic acid; with a decrease in the permeability of capillaries; stabilization of cell membranes (especially lysosomal) and membranes of organelles. It acts on all stages of the inflammatory process: it inhibits the synthesis of prostaglandins (Pg) at the level of arachidonic acid (lipocortin depresses phospholipase A2, suppresses the liberation of arachidonic acid and inhibits the biosynthesis of endoperoxides, leukotrienes, promoting inflammation, allergies, etc.), the synthesis of "pro-inflammatory cytokines" ( interleukin 1, tumor necrosis factor alpha, etc.); increases the resistance of the cell membrane to the action of various damaging factors.

 

Immunosuppressive effect is caused by induced lymphoid tissue involution, suppression of lymphocyte proliferation (especially T-lymphocytes), suppression of B-cell migration and interaction of T and B lymphocytes, inhibition of release of cytokines (interleukin-1, 2, gamma-interferon) from lymphocytes and macrophages and a decrease in the formation of antibodies.

 

The antiallergic effect develops as a result of a decrease in the synthesis and secretion of mediators of allergy, inhibition of release from sensitized mast cells and basophils of histamine and other biologically active substances, a decrease in the number of circulating basophils, T- and B-lymphocytes, mast cells; suppression of the development of lymphoid and connective tissue, reducing the sensitivity of effector cells to mediators of allergy, inhibition of antibody formation, changes in the immune response of the body.

 

In obstructive airway diseases, the effect is mainly due to inhibition of inflammatory processes, prevention or reduction of mucosal edema, a decrease in the eosinophilic infiltration of the submucosal layer of the bronchial epithelium and the deposition of circulating immune complexes in the bronchial mucosa, as well as inhibition of erosion and desquamation of the mucosa.Increases the sensitivity of beta-adrenergic receptors of small and medium-sized bronchial tubes to endogenous catecholamines and exogenous sympathomimetics, reduces the viscosity of mucus by reducing its production.

 

Suppresses the synthesis and secretion of ACTH and, again, the synthesis of endogenous GCS.

 

It inhibits connective tissue reactions during the inflammatory process and reduces the possibility of scar tissue formation.

 

The peculiarity of the action is a significant inhibition of the pituitary function and a virtually complete absence of mineralocorticosteroid activity.

 

Doses of 1-1.5 mg per day depress the function of the adrenal cortex; the biological half-life is 32-72 hours (the duration of oppression of the hypothalamic-pituitary-cortical adrenal gland system).

 

The strength of the glucocorticoid activity of 0.5 mg of dexamethasone corresponds to approximately 3.5 mg of prednisone (or prednisolone), 15 mg of Hydrocortisone or 17.5 mg of cortisone.

 

Pharmacokinetics

 

Easily passes through the histohematological barriers (including through blood-brain and placental). Metabolised in the liver (mainly by conjugation with glucuronic and sulfuric acids) to inactive metabolites. It is excreted by the kidneys (a small part by the lactating glands).

 

Indications

 

Diseases requiring the introduction of high-speed GCS, as well as cases where oral administration of the drug is not possible:

  • endocrine diseases: acute insufficiency of the adrenal cortex, primary or secondary insufficiency of the adrenal cortex, congenital hyperplasia of the adrenal cortex, subacute thyroiditis;
  • shock (burn, traumatic, operating, toxic) - with ineffectiveness of vasoconstrictors, plasma-substituting drugs and other symptomatic therapy;
  • cerebral edema (with a brain tumor, craniocerebral trauma, neurosurgical intervention, cerebral hemorrhage, encephalitis, meningitis, radiation injury);
  • asthmatic status; severe bronchospasm (exacerbation of bronchial asthma, chronic obstructive bronchitis);
  • severe allergic reactions, anaphylactic shock;
  • rheumatic diseases;
  • systemic connective tissue diseases;
  • acute severe dermatoses;
  • malignant diseases: palliative treatment of leukemia and lymphoma in adult patients; acute leukemia in children; hypercalcemia in patients with malignant tumors, with the impossibility of oral treatment;
  • blood diseases: acute hemolytic anemia, agranulocytosis, idiopathic thrombocytopenic purpura in adults;
  • severe infectious diseases (in combination with antibiotics);
  • in ophthalmic practice (subconjunctival, retrobulbar or parabulbar injection): allergic conjunctivitis, keratitis, keratoconjunctivitis without epithelial damage, iritis, iridocyclitis, blepharitis, blepharoconjunctivitis, scleritis, episcleritis, inflammation after eye injuries and surgical interventions, sympathetic ophthalmia, immunosuppressive treatment after transplantation cornea;
  • local application (in the area of ​​pathological education): keloids, discoid lupus erythematosus, annular granuloma.

 

Forms of release

 

Tablets 0.5 mg.

 

Solution in ampoules for intravenous and intramuscular injection (injections for injections) 4 mg / ml.

 

Ophthalmic eye drops 0.1%.

 

Ophthalmic suspension 0.1%.

 

Instructions for use and dosage

 

The dosage regimen is individual and depends on the indications, the patient's condition and his reaction to therapy. The drug is administered intravenously slowly by jet or drip (in acute and urgent conditions); intramuscularly; possibly also local (in pathological education) introduction.To prepare a solution for intravenous drip infusion (dropper), an isotonic solution of sodium chloride or a 5% solution of Dextrose should be used.

 

In an acute period with various diseases and at the beginning of therapy, Dexamethasone is used in higher doses. During the day, you can inject 4 to 20 mg of Dexamethasone 3-4 times.

 

Doses of the drug for children (intramuscularly):

 

The dose of the drug for substitution therapy (with adrenal cortex insufficiency) is 0.0233 mg / kg body weight or 0.67 mg / m2 body surface area, divided into 3 doses, every 3rd day or 0.00776 - 0.01165 mg / kg body weight or 0.233 - 0.335 mg / m2 body surface area daily. For other indications, the recommended dose is from 0.02776 to 0.16665 mg / kg body weight or 0.833 to 5 mg / m2 body surface area every 12-24 hours.

 

When the effect is achieved, the dose is reduced to a maintenance dose or until the treatment is discontinued. The duration of parenteral use is usually 3-4 days, then switch to maintenance therapy with dexamethasone in tablets.

 

Long-term use of high doses of the drug requires a gradual dose reduction in order to prevent the development of acute adrenocortical insufficiency.

 

Drops

 

Conjunctival, adults and children over 12 years with acute inflammatory conditions: 1-2 drops 4-5 times a day for 2 days, then 3-4 times a day for 4-6 days.

 

Chronic conditions: 1-2 drops 2 times a day for a maximum of 4 weeks (no more).

 

In postoperative and post-traumatic cases: starting from the 8th day after surgery for strabismus, retinal detachment, cataract extraction and from the time of injury, 1-2 drops 2-4 times a day for 2-4 weeks; with antiglaucoma filtering operation - on the day of surgery or the day after it.

 

Children from 6 to 12 years with allergic inflammatory conditions: 1 drop 2-3 times a day for 7-10 days, if necessary, treatment is continued after 10 days of monitoring the condition of the cornea.

 

Side effect

 

Usually Dexamethasone is well tolerated. It has a low mineralocorticoid activity, i.e. its effect on water-electrolyte exchange is small. As a rule, low and medium doses of Dexamethasone do not cause delays in sodium and water in the body, increased excretion of potassium. The following side effects are described:

  • decreased glucose tolerance;
  • Steroid diabetes mellitus or manifestation of latent diabetes mellitus;
  • oppression of adrenal function;
  • Isenko-Cushing syndrome (moonlike face, pituitary-type obesity, hirsutism, increased blood pressure, dysmenorrhea, amenorrhea, muscle weakness, striae);
  • delay in sexual development in children;
  • nausea, vomiting;
  • pancreatitis;
  • steroid ulcer of the stomach and duodenum;
  • erosive esophagitis;
  • gastrointestinal bleeding and perforation of the wall of the gastrointestinal tract;
  • increased or decreased appetite;
  • indigestion;
  • flatulence;
  • arrhythmias;
  • bradycardia (up to cardiac arrest);
  • increased blood pressure;
  • hypercoagulation;
  • thromboses;
  • euphoria;
  • hallucinations;
  • affective insanity;
  • depression;
  • paranoia;
  • increased intracranial pressure;
  • nervousness or anxiety;
  • insomnia;
  • dizziness;
  • headache;
  • convulsions;
  • increased intraocular pressure with possible damage to the optic nerve;
  • propensity to develop secondary bacterial, fungal or viral infections of the eyes;
  • trophic changes of the cornea;
  • exophthalmos;
  • sudden loss of vision (with parenteral administration in the area of ​​the head, neck, nasal concha, scalp may deposition of drug crystals in the vessels of the eye);
  • hypocalcemia;
  • weight gain;
  • negative nitrogen balance (increased protein breakdown);
  • increased sweating;
  • fluid retention and sodium (peripheral edema);
  • slowing growth and ossification processes in children (premature closure of epiphyseal growth zones);
  • osteoporosis (very rare - pathological bone fractures, aseptic necrosis of the head of the humerus and femur);
  • rupture of muscle tendons;
  • delayed healing of wounds;
  • steroid acne;
  • stria;
  • propensity to develop pyoderma and candidiasis;
  • skin rash;
  • itching;
  • anaphylactic shock;
  • local allergic reactions.

 

Local with parenteral administration: burning, numbness, pain, tingling at the injection site, infection at the injection site, rarely - necrosis of surrounding tissues, scar formation at the injection site; atrophy of the skin and subcutaneous tissue with the / m introduction (especially dangerous is the introduction to the deltoid muscle).

 

Contraindications

 

For short-term use according to vital indications, the only contraindication is hypersensitivity to dexamethasone or the components of the drug.

 

In children during the growth period, SCS should be used only in absolute indications and under the strictest supervision of the attending physician.

 

With caution, the drug should be administered in the following conditions and conditions:

  • gastrointestinal diseases - peptic ulcer of stomach and duodenum, esophagitis, gastritis, acute or latent peptic ulcer, newly created intestinal anastomosis, ulcerative colitis with perforation or abscessing threat, diverticulitis;
  • parasitic and infectious diseases of a viral, fungal or bacterial nature (currently or recently transferred, including recent contact with a patient) - herpes simplex, herpes zoster (viremic phase), chicken pox, measles; amebiasis, strongyloidiasis; systemic mycosis; active and latent tuberculosis. The use in severe infectious diseases is permissible only against the background of specific therapy.
  • pre- and post-vaccination period (8 weeks before and 2 weeks after vaccination), lymphadenitis after BCG vaccination;
  • immunodeficiency states (including AIDS or HIV infection);
  • diseases of the cardiovascular system (incl.recently suffered myocardial infarction - in patients with acute and subacute myocardial infarction, a foci of necrosis may develop, a delay in the formation of scar tissue and, as a consequence, a rupture of the heart muscle), severe chronic heart failure, hypertension, hyperlipidemia);
  • endocrine diseases - diabetes mellitus (including a violation of carbohydrate tolerance), thyrotoxicosis, hypothyroidism, Itenko-Cushing's disease, obesity (3-4 items)
  • severe chronic renal and / or hepatic insufficiency, nephrourolythiasis;
  • hypoalbuminemia and conditions predisposing to its occurrence;
  • systemic osteoporosis, myasthenia gravis, acute psychosis, poliomyelitis (except for the form of bulbar encephalitis), open and closed angle glaucoma;
  • pregnancy.

 

Application in pregnancy and lactation

 

In pregnancy (especially in 1 trimester), the drug can be used only when the expected therapeutic effect exceeds the potential risk to the fetus. With prolonged therapy during pregnancy, the possibility of impaired fetal growth is not ruled out. In case of application at the end of pregnancy there is a risk of atrophy of the adrenal cortex in the fetus,which may require replacement therapy in a newborn.

 

If it is necessary to carry out treatment with the drug during breastfeeding, then breastfeeding should be discontinued.

 

special instructions

 

During treatment with dexamethasone (especially long-term) it is necessary to observe the oculist, monitor blood pressure and the state of water-electrolyte balance, as well as patterns of peripheral blood and blood glucose levels.

 

To reduce side effects, antacids can be prescribed, and K + intake should be increased (diet, potassium preparations). Food should be rich in proteins, vitamins, with a restriction of fat, carbohydrates and table salt.

 

The effect of the drug is enhanced in patients with hypothyroidism and liver cirrhosis. The drug may enhance existing emotional instability or psychotic disorders. When referring to psychoses in an anamnesis, Dexamethasone is given in high doses under strict doctor's supervision.

 

With caution should be used in acute and subacute myocardial infarction - possibly spreading the focus of necrosis, slowing the formation of scar tissue and rupture of the heart muscle.

 

In stressful situations during maintenance treatment (for example, surgical operations, trauma or infectious diseases), a correction of the dose of the drug should be made in connection with an increase in the need for glucocorticosteroids. the patients should be carefully monitored for one year after the end of a long dexamethasone in connection with the possible development of relative adrenal insufficiency in stressful situations.

 

With the sudden cancellation, particularly in the case of the prior use of high doses may develop the syndrome of "lifting" (anorexia, nausea, lethargy, generalized musculoskeletal pain, fatigue), as well as worsening of the disease, about which he was appointed Dexamethasone.

 

During treatment, Dexamethasone should not be vaccinated due to a decrease in its effectiveness (immune response).

 

Assigning Dexamethasone with intercurrent infections, septic conditions, and tuberculosis, treatment with antibiotics is necessary to simultaneously bactericidal action.

 

Children during long-term treatment with Dexamethasone need careful monitoring of the dynamics of growth and development.Children who were in contact with sick measles or chickenpox during the treatment period prophylactically prescribe specific immunoglobulins.

 

Due to the weak mineralocorticoid effect for replacement therapy with adrenal insufficiency, Dexamethasone is used in combination with mineralocorticoids.

 

Patients with diabetes should monitor blood glucose and, if necessary, correct therapy.

 

An x-ray control of the osteoarticular system (images of the spine, hands) is shown.

 

In patients with latent infectious diseases of the kidneys and urinary tracts, Dexamethasone is able to cause leukocyturia, which can be of diagnostic significance.

 

Drug Interactions

 

The pharmaceutical incompatibility of dexamethasone with other intravenous drugs is possible. It is recommended that it be administered separately from other drugs (iv bolus, or via another drip as a second solution). When a solution of dexamethasone is mixed with heparin, a precipitate forms.

 

Simultaneous administration of dexamethasone with:

  • inducers of hepatic microsomal enzymes (phenobarbital, rifampicin, phenytoin, theophylline, ephedrine) leads to a decrease in its concentration;
  • diuretics (especially thiazide and inhibitors of carbonic anhydrase) and amphotericin B - can lead to increased excretion of K + from the body and an increased risk of developing heart failure;
  • with sodium-containing drugs - to the development of edema and increased blood pressure;
  • cardiac glycosides - their tolerance is worsened and the probability of ventricular extrasitolia increases (due to hypokalemia caused);
  • indirect anticoagulants - weakens (less intensifies) their effect (dose adjustment required);
  • anticoagulants and thrombolytics - the risk of bleeding from ulcers in the digestive tract increases;
  • ethanol (alcohol) and non-steroidal anti-inflammatory drugs - increased risk of erosive ulcerative lesions in the gastrointestinal tract and development of bleeding (in combination with NSAIDs in the treatment of arthritis, a decrease in the dose of glucocorticosteroids due to the summation of the therapeutic effect);
  • paracetamol - the risk of hepatotoxicity increases (induction of hepatic enzymes and the formation of a toxic metabolite of paracetamol);
  • Acetylsalicylic acid - acceleratesits elimination and reduces the concentration in the blood (with the abolition of dexamethasone, the level of salicylates in the blood increases and the risk of side effects increases);
  • insulin and oral hypoglycemic drugs, hypotensive drugs - their effectiveness decreases;
  • vitamin D - its effect on absorption of Ca2 + in the intestine is reduced;
  • somatotropic hormone - reduces the effectiveness of the latter, and with praziquantel - its concentration;
  • M-holinoblokatorami (including antihistamines and tricyclic antidepressants) and nitrates - contributes to increased intraocular pressure;
  • isoniazid and mexiletine - increases their metabolism (especially in "slow" acetylators), which leads to a decrease in their plasma concentrations.

 

Inhibitors of carbonic anhydrase and looped diuretics can increase the risk of osteoporosis.

 

Indomethacin, displacing dexamethasone from a bond with albumin, increases the risk of developing its side effects.

 

ACTH increases the effect of dexamethasone.

 

Ergocalciferol and parathyroid hormone interfere with the development of osteopathy caused by dexamethasone.

 

Cyclosporine and ketoconazole, slowing the metabolism of dexamethasone, may in some cases increase its toxicity.

 

Simultaneous appointment of androgens and steroid anabolic drugs with dexamethasone promotes the development of peripheral edema and hirsutism, the appearance of acne.

 

Estrogens and oral estrogen-containing contraceptives reduce the clearance of dexamethasone, which may be accompanied by an increase in the severity of its action.

 

With simultaneous use with live antiviral vaccines and against other types of immunization increases the risk of virus activation and the development of infections.

 

Antipsychotic drugs (antipsychotics) and azathioprine increase the risk of developing cataract in the appointment of dexamethasone.

 

With simultaneous use with antithyroid drugs is reduced, and with thyroid hormones - increases the clearance of dexamethasone.

 

Analogues of the drug Dexamethasone

 

Structural analogs for the active substance:

  • Decadron;
  • Dexaven;
  • Dexazone;
  • Dexamed;
  • Dexamethasone buff;
  • Dexamethasone Nycomed;
  • Dexamethasone-Betalek;
  • Dexamethasone-Vial;
  • Dexamethasone-LENS;
  • Dexamethasone-Ferein;
  • Dexamethasone sodium phosphate;
  • Dexamethasone phosphate;
  • Dexamethasone-lang;
  • Dexapos;
  • Dexafar;
  • Dexon;
  • Maxidex;
  • Oftan Dexamethasone;
  • Fortecortin.

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Reviews (215):
Visitors
Dmitry40
Ataras I buy without a prescription in different pharmacies, I took 2 tablets each, when I could not sleep.
Administrators
admin
Dmitry40, After Atarax, Tenoten probably will not help you. And the fact that we have a pharmacy is a quiet horror.
Visitors
Dmitry40
Thank you. I will continue to look for options, replace dexamethasone, with minimal side effects!
Visitors
Nastya123
Hello. Gynecologist diagnosed with hyperplasia, povysh. prolactin and multifocal ovaries. Has appointed or nominated preparations the necessary (type and, a cyclovitis) and dexamethasone on 1/4 tablets for the night within 2 months.Question: I often have herpes on the lip, in the instructions of Dexamethasone it is prescribed that with caution - herpes simplex. Can I apply it, like a dose small? And the gradual abolition of the drug was not given, they said just 2 months. and everything, for tests. Again, the instructions say that you need to gradually cancel Dexamethasone. In advance thanks for the answer.
Administrators
admin
Nastya123Doses of Dexamethasone are really small. How the hormonal drug will manifest itself in the impact on the body - no one can tell reliably until you try, but on a quarter tablet it's a dosage lower than the lower one. There is a high probability that nothing bad will happen, including the impact on herpes simplex.

Gradual cancellation of such small doses of drugs also do not assume, simply because dividing into a smaller tablet does not make any sense and it is technically difficult.
Visitors
Julia 31
Hello, tell me please, how to be? My son is 6 years old. He had pneumonia, and then an obstruction, he coughed and whistled.In a private clinic, he injected 2 ampoules of Dexamethasone. After we were offered hospitalization in the allergic department and put asthma in question. There he was given 2 droppers with dexamethasone 2 ampoules (ie 4 ampoules for two days). We lay down on Monday, after the first dropper a cough and whistle disappeared. On Friday they let us go home for the weekend. At home again, there was a whistle and a cough. We went to the pulmonologist and she said that this is asthma and that the child is in a fit, it is necessary to immediately prick dexamethasone. Have stuck two more ampoules. After the first dropper in the hospital, the child began to eat a lot, he gained weight. I found another pulmonologist, it turned out that he did not have any asthma, but simply obstructive bronchitis. I canceled hormones, we breathed Pulmicorte, Ventolin and Lazolvan for another three weeks. When discharging from the hospital, the doctor said that it was not asthma and she diagnosed with obstructive bronchitis. On my question why she then appointed Dexamethasone and most importantly, why she did not tell me that it was a hormone and did not ask my permission, I was told that it happens. But he has a predisposition for asthma.
Now the child is at home. But he continues to eat a lot, recovering.I became nervous and nervous, did not let me go for a minute, just did not let me out, like a feeling of fear that he would be abandoned. What to do? And how long will this drug be in the body? Blood was given over to sugar, while it's normal.
Administrators
admin
Julia 31, Hormonal drugs can affect the human body for a month, that is, the final effect can be assessed no earlier than 4 weeks, during this time, all negative side effects should go away, but if left - this is an occasion to turn to the endocrinologist.

If the deadline does not come out, stop screwing yourself and the baby, because according to the description, it looks like a neurosis to hospitals and doctors, plus obstruction at an early age brings suffering to the young body and it's trite to fear when there is not enough air. It is necessary to calm down and stop feeding the baby, it is possible that he began to seize his stress. If 4 weeks have passed since the end of taking the medication - there is an occasion to consult a doctor, as I indicated above.
Guests
Natalochka
I'm 36 years old, from the age of 29 I'm allergic, starts from the 1st August and the end of September (started with ragweed, and now for different garden weeds).I live in such a locality, we do not have an allergist. I was advised a month before the onset of an allergy to pierce in / m 5 times a day for 1 ampoule of Dexamethasone. I began to do it in 2013, the first year the allergy was passed as they say in a mild form (a small runny nose, was saved by pills). In 2014, there was an allergic conjunctivitis, very much in strong form, a lot of puffiness was under the eyes, that even in the office at work did not remove sunglasses. And in 2015 in general there were 2 large attacks of allergy, I thought that I would not transfer them at all.
Guests
olga
Very much my husband had a backache. The shot was a fracture of the 3rd lumbar vertebra. He fell a long time, in the winter on his back. Well pobolela and has passed or has taken place, and now began often to excruciate pains. Here is my friend advised this drug - dexamethasone, she takes it with an intervertebral hernia. I did not listen to her at first, but would you bring the men to the hospital? Here on fear and risk began to prick him with pyridoxine + lidocaine. We pierce 2-3 injections of times in 3-4 months and about pains in a back he has forgotten. Diclofenac does not help.
Visitors
Tatiana2772
Hello! I am 43 years old, 6 years ago I was diagnosed with type 2 diabetes, the last 1.5 years on insulin Lantus (30 units) and Humalog (8-8-8). 2.5 months ago, after a night's sleep, noticed swollen rashes on the skin of the trunk and limbs, during the day by noon or by evening passed without a trace, turned to the dermatologist diagnosed - urticaria, appointed "Zodak" a week later went to the hospital with edema Quincke, swallowed dexamethasone, intramuscular suprastin, adrenaline, a day later the swelling from the face passed, but on the body the rashes continued. Was on the hospital at the therapist was treated with loratadine, enterosorbents, purged sodium sulfate. Then the allergist: enterosgel, desloratadine. Has handed over a heap of analyzes all within the limits of norm or rate on every possible helminths - it is negative. Was in the day hospital, pricked sodium thiosulfate, sodium chloride + dexazone 4 mg. № 3, after the first dropper urticaria gone, but sugar rose to 20 units, droppers were canceled. During the week, I felt fine, not counting the high glucose levels in my blood. A week later, everything repeated with a double force, the shedding occurs now at night throughout the body, the spots merge into a solid rash,began to terribly itch and almost do not pass! After all this treatment, I began to pull in the pancreas. Swollen lips and eyelids. Has addressed again to the therapist, again prescribe Dexamethasone. I know that it helps, temporarily, I'm afraid of the consequences, advise what to do ?!
Administrators
admin
Tatiana2772Judging by the description of all possible processes from the side of allergy, you have worked. Begin to check the remaining organs. Given the problems with diabetes, you can recommend a liver examination (often there are problems with allergies and long-term medication). Flora of the intestine from the question is normal, it's good. Maybe some of the insulin began to show allergies - the manufacturer has changed. stamp etc. is. and this became an allergy. It is worth to go to the endocrinologist and talk about the replacement of the treatment, at least for the time, in order to assess the allergy of the body to insulin. Dexamethasone, most likely, you will help this time only temporarily.
Visitors
phone_t9
Good afternoon! I have a food allergy.Ate corn porridge, after which it became unbearably bad. It takes about 10 minutes. I feel sick. I tried to induce vomiting myself, nothing happened. I begin to scratch unobtrusively, which goes into an insane state, when the whole body itches, that even skin skin. It's getting hot. I start wheezing. My throat is swollen. I touch the body and everything like in the tubercles. The skin was like a snake with such a swollen texture. Has drunk all against an allergy. But I understand the time is necessary. In the morning everything was completely gone. Was in marching conditions, where it is impossible to get medical aid. Is it possible in this case to use dexamethasone urgently?
Administrators
admin
phone_t9For the relief of severe and instant allergic reactions similar to yours, the use of injection forms of Dexamethasone, Prednisolone and other glucocorticosteroids as an emergency aid to the injured person is indicated. Any treatment should be appointed by the doctor on the basis of the full-time assessment of the patient's condition.
Visitors
POLINA88
Good afternoon.

I have an allergy to my husband, he came to the clinic and he was prescribed a three-day course of dexamethasone (12 mg on the first day, 10 mg in the second and 8 mg in the third intravenously). He had already made two droppers, and he had a lot of pressure (he was already hypertensive, and yesterday the pressure was 190/102), hiccough and tremor.

So he thinks to heal the course to the end or is it better not? The doctor says that this medicine does not influence the pressure and there should not be any adverse reactions at all.

Tell me, please, whether to do the last dropper, because there are no allergic reactions now, or is it better to finish it to cure? Are there more negative consequences from increasing the amount of medicine in the body?

Thanks in advance for the answer.
Administrators
admin
POLINA88Most likely the doctor is right. A dropper of Dexamethasone needs to be completed in order not to think about whether to cure or not and move on, to evaluate the results of the therapy. But the pressure is probably in the field of psychology lies, your husband may be overtired or the intake of pills from the pressure missed.
Visitors
Babenkova Natalya
Good afternoon. Against the background of chickenpox, my legs acutely felt (from the ankles and below). First saw "Nimesil". After his abolition the pains began to return. Rheumatologist put arthropathy, ordered ibuprofen, but he almost does not help, I can not go to work. The therapeutist has advised to prick "Dexamethasone" (a dosage 1,0 once a day 5-7 days). Whether it is necessary to me to drink ibuprofen thus or better it is not necessary? I forgot to ask the doctor.
Administrators
admin
Babenkova Natalya, I would advise you to examine your condition. And then arthropathy is like it is not the diagnosis, so that's how immediately prescribe hormone Dexamethasone. First, make an x-ray of the affected joint (as I understand from the question this is the ankle), then tests with the definition of joint markers, and then we put the diagnosis and treat. And it's just doctors guessing. First, you will be able to treat unclear arthropathy, then possible complications from the use of medications.

On the subject: Ibuprofen is permissible to use with Dexamethasone, but cautiously and only if monotherapy with one of the drugs has not brought the desired effect.Plus, the risk of developing bleeding in the gastrointestinal tract may increase, so I rarely use such combinations in my practice, as the last hope.
Guests
Fedor
A 15-year-old boy, acute lymphoblastic leukemia, remission, completed the irradiation course a week ago. Drop and so few hair, just throughout the treatment I take a two-week course of dexamethasone (every two months), there are 7 courses left. I gained 18 kg in weight in the last year of treatment, to my surprise I noticed that the main side effects of the drug begin after the end of the course, acne on the back, shoulders, face, on the head (under the hair), moonlike face, mood. The course of dexamethasone (0.5 mg) 11 table. in the morning, 10 in the evening. Acne does not pass, swells, itchs, the doctor prescribed a talker, but now it no longer helps (apparently the body is already used to the mixture). Tell me how to deal with this, or at least reduce the side effects of dex? Somewhere I read that during the adoption, you need less salt, more potassium, less carbohydrates. Dexamethasone is very dangerous, here I read that some people take it without prescribing a doctor,that in any case should not be allowed.
Administrators
admin
Fedor, On the skin of any person permanently live streptococci and mites of a special kind (obligate flora), but with immunity falling as a result of taking high doses of Dexamethasone they activate and cause the formation of hormonal acne. Better than the talkers on salicylic alcohol so far from this scourge did not come up. Can start up the prescription the doctor will change them there are some kinds (with dimeksidom, metronidazolum, etc.). Press the data of acne is not worth it - it will only get worse.
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Stanislav
Good afternoon! He put droppers dexamethasone on the appointment of a neurologist for 3 days to 4 mg. Through what time it is supposed to drink alcohol?
Next week I go to my birthday, by the time I have 10 days after the end of taking dexamethasone. Of the side effects, there was a sensation of heat in the abdomen of the day, three to four.
In advance thanks for the answer.
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admin
Stanislav, After 10 days of active Dexamethasone or its metabolites in the body should not remain.Another question is that the bell from the stomach side was and that there you have, can an ulcer, can gastritis, which can exacerbate alcohol, except for you no one knows. I'm a consistent opponent of alcohol. This is not the product without which it is impossible to live. Offer to drink, say that antibiotics and all of you will be left behind.
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Bella
Dexamethasone is prescribed by chemotherapists for chemotherapy in the treatment of oncology. As a premedication before and during the introduction of chemotherapy drugs, as well as for raising leukocytes, which tend to fall during chemistry. Weight of course is typed, if you eat everything. And if you exclude salt, carbohydrates, do not eat at night (in short, eat the most correctly), then the weight is not typed. A maximum of one or two kg at the expense of water, which then will go away. Such are the cases!
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Larisa Untilova
My husband had a cold for 20 years. They offered to break the septum in the nose, they offered dexamethasone in the pharmacy, pierced 7 injections, everything went without side effects.
I myself cough more than 5 years, lay several times in the hospital. They recognized asthma, but inhalers do not help.At my own risk and risk I decided to pierce, I will take 4 injections and look at the result. Coughing tortured.
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admin
Larisa UntilovaI usually do not comment on self-medication. Everyone is responsible for his own health. The lack of a sufficient number of qualified specialists in the field of the scourge of modern Russia.
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Anna10999
Hello. The child has been ill with bronchitis for 2 years. Assigned ceftriaxone and dexamethasone intravenously, but after a dropper, she vomits. Is this a normal reaction?
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admin
Anna10999Vomiting is an abnormal, transcendental side reaction. Contact the child's attending physician to identify the wrong drug, replace it, or change the treatment tactics. To blame for this side effect may be and Dexamethasone, and antibiotic Ceftriaxone in equal parts.
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Lynx
Hello. I am 44 years old. Month they treated tonsillitis and osteochondrosis, pricked ceftriaxone for 7 days, drank a lot of medications for tonsillitis.A month later, the neck formed edema, swallowing became painful, the constant presence of coma, it is impossible to lie. I went to a city hospital, and a subacute thyroiditis was diagnosed. After has made uzi in an out-patient department and has handed over analyzes on hormones of a thyroid gland. TTG is very understated. The doctor prescribed treatment today for 15 mg of dexamethasone per day. How to drink it did not say. Also to my question about what I'm taking Yarin + said that it's okay. In the pharmacy, I found this drug, only in a dosage of 0.5 mg and I sasalized that there are no other dosages. It turns out that I need to take 30 tablets a day? Is not that much? Especially since the acute phase, I already took off the course of Diclofenac (today was the last injection). Tell me, please, how to be and how to drink this hormone? Is it possible to combine it with Yarina + (in the instructions it seems like it is not). If not, how can I deal with Yarina? Today is the 5th day of admission, after menstruation. If I give up the contraceptive, what can I expect? And yet, I have gastritis. I'm very concerned about how my stomach reacts to Dexamethasone, especially since only 5 days ago, I finished the Ceftriaxone course. Sorry that everything is so confusing written, but in the clinic the doctor really did not say what (((I hope for an answer.
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admin
LynxIn your story, I also have questions, because here and Diclofenac because of something appeared, although it was originally about subacute thyroiditis, which is treated with hormones selected by an endocrinologist depending on the results of tests and other studies of the thyroid gland.

As for Dexamethasone, everything was correctly told in the pharmacy, it does not exceed 0.5 mg, so I can say for sure that the doctor thought about one thing and wrote out another. There is a dosage of tablets of Prednisolone 5 mg, and this is not 30 tablets, but only 3 tablets per daily intake. Most likely to you have written out Prednisolonum, but it is necessary to specify it at your attending physician.

To protect the stomach, while taking Prednisolonum or Dexamethasone, you can take an inhibitor of the proton pump (Omeprazole, Omez, Pantoprazole and other preparations) 30 minutes before meals on an empty stomach. This will protect the mucosa of the gastrointestinal tract.

At the reception of Yarina Dexamethasone or Prednisolone should not exert any influence, in this the doctor was right.
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Lynx
Hello.Thanks for the quick response. Diclofenac was appointed to me as a therapist to relieve pain in the neck, and in the evening my head and ears ached. Therefore, this drug was prescribed. On it the condition improved, and after 2 days of its application, a subacute thyroiditis was already diagnosed and confirmed. All this time before (almost a month) I was treated for tonsillitis. The doctor, prompt, please, - I this morning have called the doctor and have told or said about dosage Dexametazona. She said - "Drink then Prednisolone, 10 mg - 3 times a day." I asked how to drink it, you need to drink all 30 mg before lunch? (because the instructions say that it is drunk in the morning hours). She answered - "Yes, drink according to the instructions." And now again I have confusion, since the instructions say that the average dose can be divided into 2 divided doses. Be so kind, please tell me. Prednisolone ran off already. Ready to drink for the time being "morning" I do not know how. Thanks for the answer.
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admin
Lynx, This dosage can be drunk at one time. The main thing we remember is that the subsequent cancellation of Prednisolone should be done gradually, reducing the dosage of the medicine taken for a long time.

And yet, if you do not correct mistakes that I am correcting for you, I will not publish the next question and will not answer. Ward or something similar to any computers is. Native speakers should be able to write on it at least with minimal errors. I consider this as disrespect to the interlocutor.
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aida
Hello. Lor has diagnosed neuritis of the auditory nerve on the left 16 September. I prescribed dexamethasone 8 mg twice a day intramuscularly for 5 days plus trental, pyracetam, demato on the background of not treated pharyngitis. After five days of dexamethasone (every other day) on September 22, pharyngitis became worse, conjunctivitis and bronchitis joined. There was a strong weakness, the face swelled. I drank 7 days of tawanik. Pharyngitis, bronchitis passed, my face was asleep. On September 30, vitrum Vitrum was prescribed 30 days, bronchomunal 10 days, betaserk for a long time. The treatment of eustachyte (electrophoresis with Lidase No. 5 and pneumomassage of tympanic membrane No. 10). The treatment was completed a week ago. The hearing improved. October 10, there was an itch in the palms, the skin dry as if thinned. Today, swelling on the face and legs.From what? Very much I am afraid of hormonal disturbances, any remote consequences. How long does dexamethasone and side effects occur? Do they pass? Or is it forever? Thank you.
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admin
aida, Side effects can be prolonged, sometimes even a month. Usually everything passes, if not - I send these patients to the endocrinologist, where they take the necessary tests and the doctor prescribes corrective therapy. You have tried so many medicines for 1 month that there may not be a case in Dexamethasone. Either something from the last that you took or takes gave an allergic reaction, or it is a general reaction to the organisms for high drug load. If tolerable, you can stop taking all the medicines and vitamins and look at the week, if not - go to the doctor and look for the cause of the changes.
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Milena
Hello. After an injury on a water attraction, I have an offset from 1 to 5 vertebrae, instability. There was a numbness of the left little finger and the next finger, and also a strip of a hand to an elbow, and a veil (scotoma) in front of the right eye.They made mrt with contrast found foci lesions in the head (1 in the subcortical zone of the right frontal) and mnogochagovost in the dorsal cervical section. The neurologist drilled to mrt l lysine, actovegin, neuroxon, neuroplex, mexprin, midostad and nucleo. After mri I was diagnosed with clinical isolated syndrome, optic neuritis, pricked 3p methylprednisolone 500 (effect of numbness of fingers 2 went to 50%), pentoxifylline, dialipon, milgamma and Table omeprazole + Aluminum phosphate gel. Rapid effect did not give and after 5 days, chopped retrobulbar diprospan 1 ml. At the same time the veil on the eye decreased in strength, but still occurs when using hot tea, soup, etc. I went to another neurologist, and she told me donaznachila dexamethasone 32 mg 5 days, 10 days thiotriazolin №5, dialipon 600 mg / d, vitakson 10 days, besides that I drink Noofen, pentoxifylline and retrobulbarno me kolyat cerebrolysin. Prompt please do not hurt me dexamethasone? In advance thanks for the answer.
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admin
MilenaSince there is a response to hormones, they show you. That's all I can tell you based on your difficult case.Such questions are resolved on internal reception with the analysis of the whole medical history, previous treatment and all studies and analyzes. Throughout the described medical history, I do not see anything wrong or wrong, but the point is in nuances. Consult with different neurologists, collect information, an extraordinary business.
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Alexandra1983
Hello! The doctor rheumatologist diagnosed - undifferentiated arthritis, probably early rheumatoid on the background of osteoarthritis with predominant lesion of small joints (Rst 1, fk2) bilateral longitudinal flatfoot. Has sent on the further inspection. Rheumatoid factor is questionable. Has registered while deksamed 4 mg (1 ml) v / m in the morning of 10 days, movalis, etc. Tell me please, somehow you can do without dexamed, I'm much afraid to do more harm than to help myself. A common horrible state, if any of the side effects are added to this, it will be bad. Maybe something is "not hormonal"?
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tatiana000113
Good afternoon, at me the hormone 17-OP - 1,15 ng / ml is raised or increased.A gynecologist prescribed dexamethasone for 1t. Once a day, I take about two months. After consultation, the gynecologist-endocrinologist recommended to cancel dexamethasone and start taking vitamin C (ascorbic acid 1000 mg.). Tell me which one is right? And can I stop taking dexamethasone in my case or do I need a gradual exit?
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admin
Alexandra1983, As an anti-inflammatory you are discharged Mawalis, this is a strong non-steroidal anti-inflammatory drug. To understand whether this drug is sufficient to inhibit the inflammatory process without a full-time examination and examinations is difficult. Apparently a strong inflammation in the joints, since the doctor additionally prescribed a hormonal drug for its suppression. So you can risk and cancel Dexamed yourself, but see what's more important to you, possible side effects or a reduction in joint pain. I would share such doubts with the attending physician.
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admin
tatiana000113, The first time I hear about the treatment of excess 17-OP with large doses of vitamin C, smacks of some kind of homeopathy from such therapy. The withdrawal from a long course of taking Dexamethasone should be gradual. In your situation, first half a tablet a day take about a week, and then you can completely and completely cancel the hormone.
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Raimy
Good afternoon. I am 24 years old. I was tormented by terrible pimples on my face and on my chin, my hair fell very badly. Has handed over analyzes and has addressed to the endocrinologist. Results of the tests: testosterone 5.2 at a rate of 0.5-4.3 nmol / L, DHEA 3.9 at 0.8-3.9 μg / ml and androstenedione: 7.7 at a rate of 0.75-3.89 ng / ml, the rest of the hormones said normal. Analyzes handed over on the 3rd day menstr.cycle. Diagnosis: hyperandrogenia. Treatment: Dexamethasone 1/4 tab. in the morning, Veroshpiron 25 mg from the 14-28 day cycle. The course is 3 months. Also, Tsinkit during the first month. Tell me please, is the treatment right? And if I do fitness, will I be able to maintain my weight 47 kg or still gain weight? Thank you in advance!
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admin
RaimyIf it were not for acne, one could try oral treatment with Dexamethasone, but acne indicates the likely adrenal origin of the disease, so it is better to follow the course of therapy recommended by the treating doctor. By the way, treatment is literate, doses are minimal enough, I want to believe that it will help you lose weight too, but the latter only depends on your body. Fitness can be done. Any injecting injections and cocktails for muscle mass use are contraindicated, hormones or hormone-like substances are usually added in them, and with your problems this can be fraught.
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Tatyana
Hello. I have a very severe rash all over my body and severe itching. The dermatologist diagnosed an allergy - diazolin, valerian, acryderm ointment, calcium gluconate injections. It became worse. Already the whole body is covered and combed. I did one injection of this medicine, the itching passed. After 10 hours, the itch repeated.
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Krk
The worst drug, when it is used for wheezing, asthma, bronchospasm, it increases blood sugar,and also after the introduction irreversible changes occur in the lungs and bronchi, because of it there is water in the lungs and much bad. Our medicine can not heal plus arrogance.
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Irina
Tell me, please, yesterday after taking the tablets the bronchitis formed red spots on the chest, the body became wadded, and it was hard to breathe. Arrived an ambulance was injected Calcium gluconate 0.9% and dexamethasone 2.0. What are the consequences? Can I recover?
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admin
Irina, One-off injections of hormonal drugs usually pass without consequences for patients in terms of gaining excess weight.
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anetik83
Good afternoon! Mamé (59 years old) was diagnosed with multiple myeloma and Mirin and dexamethasone 20 mg were prescribed. - take concomitantly with the main drug the first 5 days on a monthly basis. In the pharmacy there is only 0.5 mg. dexamethasone. Does this mean that you need to take 40 tablets? Or we misunderstood the prescription of the doctor. Or are there other doses? It's impossible to get to the doctor now. I went on leave, there is no connection with her, and I need to start treatment already. In advance thanks for the answer.
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admin
anetik83If the doctor did not get it wrong, then take 40 tablets. Dexamethasone in tablets is found only in a dosage of 0.5 mg, the injection form goes to 4 mg. Typically, these dosages are divided into several doses per day, rather than one-time, but the dosage is still the highest possible, but the diagnosis is not easy. Oncology has its own laws and dosages.

It is possible, of course, and a medical error to assume, when instead of Dexamethasone the doctor wanted to prescribe Prednisolone, it occurs in a dosage of 5 mg, but it is already necessary to look at what is written out and consult with the attending physician again.
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Svetlana.ka
Hello! The neurologist prescribed 5 injections of dexamethasone (I had intervertebral hernias and protrusions in the cervical spine) stabbed amelotex, milgamma, chondrolon, but there is no result. How justified is the appointment of hormones, will it help? Thank you.
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Svetlana.ka
If the first injection has passed without consequences, you can hope that the others will also pass? Or does it not apply to dexamethasone? Thank you.
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dildor
My mother had a swollen face after the injection of dexamethasone.
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admin
Svetlana.ka, Hormones help immediately and quickly, the main thing then to develop the achieved positive effect of using drugs of this group. There must be muscle spasms, pain. Since the muscles will become elastic, the blood flow to the sites of pathological reaction will increase, the delivery of medicines to the focus of pain and spasm will become available. It's time to do medical gymnastics, physiotherapy, massage plus after the injection of Dexamethasone, you can take the course of the same Milgramam, Chondrolon and other drugs to eliminate the pathogenesis of osteochondrosis.

Svetlana.ka, This is the probability and all are different. But if the first injection of any medicine, not only Dexamethasone, has gone without consequences, then the chances of successful completion of the entire course of treatment are significantly increased.
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Oksana M.
Hello! If, with a dexamethasone sample, he was drunk not at 23.00, but 20 minutes later - the results are not valid?
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admin
Oksana M., It is most likely a shortened version of dexamethasone test, when the drug is taken at 23.00, and the results are evaluated at 8.00 the next morning. 20 minutes per sample should not be affected and the results can be considered reliable. In any case, verification of the diagnosis by other methods and clinical data is required.
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sveta20
Hello, my husband, an orthopedist recommended the introduction of dexamethasone in the knee joint. After reading all the comments, I did not see a single patient who would be recommended this way of treatment. Tell me, please, how much is it justified? Thank you.
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admin
sveta20, The introduction of glucocorticosteroid drugs into the cavity of the inflamed joint is practiced. Usually the effect is positive and patients quickly feel better (stiffness, pain and inflammation disappear, quality of life rises). However, there is also the reverse side - hormones have a catabolic effect and can enhance the course of chondrodestructive diseases, for example, with arthrosis.Therefore, appoint or not the same Dexamethasone is intra-articulated by the patient's attending physician.
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Nanoria
Good afternoon. Prompt, please, on a background of a genyantritis and a cyst in doubt while ENT has written out to me antibiotics and nyxes deksametazona 4 mg / 1 ml 3 days to prick on 1 time. I pierced, but read that the cancellation should be gradual. How to understand that the work of the adrenal glands has not been disturbed? From the side, she gained a little weight in her stomach and at night woke up in a cold sweat. Thanks in advance.
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admin
NanoriaThe reception of Dexamethasone by a short course of 3 days does not require a gradual cancellation and it is possible to cancel the hormone at the same time. No additional side effects from this should arise. All the side effects must pass within a month. If after this period there remains something that delivers real problems in life and / or health - then it is better to contact the endocrinologist and he will appoint you tests and additional studies. On the description of the issue, I see no special problems, so you can wait and watch yourself.
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mary29
Good evening.I was pricked with a herniated intervertebral disc. Weight gained 5 kg very quickly. The body became poured. At first, I very much wanted to eat everything.
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Anna12345679465
Hello! I am 33 years old. After the dexamethasone test (about adrenal adrenal glands), the entire body went out of action: sparks in the eyes when working at the computer, I'm afraid to make an unnecessary movement - the joints crunch so that they are about to jump out, hurt the bones, periodically throws them into fever, when you drive directly to your car. All this has been going on for more than a year. I will never take Dexamethasone again, even if a doctor prescribes. If I take it again, I'll die.
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NETT
Good afternoon. All my life I suffer from neurodermatitis. Sometimes I just can not stand it, the skin is red, itches, I look terrible. When there was a very severe exacerbation, the doctor prescribed dexamethasone in tablets, I do not remember how many, but not less than 15 pieces at first, drank according to the scheme. Then after a couple of years I turned again, but already in another city, they refused me, said that I would stay without the liver.And since other treatments did not help, she bought and drank, starting with 5 tablets, gradually reducing. The effect is already felt on the second day. Suffices for 2-4 months of improvement. I want to ask - at such small doses, are the consequences as terrible as doctors scare, refusing explanations and simply do not want to discuss this treatment, but prescribe all the nonsense useless? I am not treated more often than once every six months or a year.
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admin
NETTAnd why they can not repeat the normal course of treatment with Dexamethasone, given that his actions were enough for a couple of years without exacerbations? Of course, with a lot of small hormone courses, you can drive your body faster than one regular dosage that is adequate to your condition. We must immediately tell the doctors that they took everything they could, and this was the course Dexamethasone helped. Most of the adequate doctors repeat the methods that help the patient.
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NETT
Thanks for the answer. Because I do not remember which course helped, that is, what dose. And this is another doctor.Now again started to drink, but the effect is not the same, and you can not quit, you'll have to drink it. In this connection, the question is whether it is possible to take vitamins B, A, nicotine, D, E during the intake of dexamethasone. And then the skin is very dry, and dexamethasone helped not to itch and took off the inflammation, but nothing more. I, of course, understood that it is harmful and I will not take it anymore, but what should I do now? I'll go to the doctor next time, now there is no sense, I will not give up drinking it sharply, it is written that it is impossible.
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Tatyana
Hello! My son had a noise in his right ear, went to see a doctor, prescribed treatment: vinpocetine, dexamethasone in droppers, actovegin. After the procedure, a strong weakness, the muscles of the arms derevyayut, swell.
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admin
NETTThe listed vitamins with Dexamethasone can be taken. Any doctor prescribed in the past can see the documentation in the documentation, for some reason they always write all these cards :) If it was a paid specialist, then an advisory opinion on the paper with the doctor's seal should remain.Documents related to health should be better collected and not discarded.
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Lilia
We helped Movalis, her husband hurted a back-hernia, which is better to prick? The doctor recommends Dexamethasone, but he has so many side effects. What do you advise, proven Movalis + vitamin B or Dexamethasone?
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admin
Lilia, Dexamethasone has an anti-inflammatory effect stronger than that of Movalis, but there are more side effects as well. So this is a question that is dealt with physician internally, and not remotely. In the case of your husband, general recommendations may not work.
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TankTank
Good afternoon. My wife was prescribed such treatment for infertility: Dexamethasone 0.5 mg once a day; Veroshpiron 100 mg. 1 time per day; Siofor 500 mg. 2 times a day; Folic acid 1 mg. 1 time per day. It has been treated for 7 months. Weight increased by 5 kg., No other side effects are observed. 3 months ago, I managed to get pregnant, but an early miscarriage occurred. The doctor is not going to change the scheme of treatment before pregnancy.How dangerous for my wife is this prolonged intake of dexamethasone and how can it affect the unborn child? Thank you.
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admin
TankTankInfertility has a lot of reasons. Apparently, your wife has hormonal disorders associated with defects in the metabolism of corticosteroid hormones. To say more from the available information is difficult for me. Prolonged intake of hormones, of course, can affect both pregnancy and fetal development, but I understand that there is no choice. In the protocols of in vitro fertilization or IVF (as an alternative), other hormones are used, but without the normalization of the hormonal background of corticosteroids, there is great doubt that even artificial insemination will not ultimately result in miscarriage.

And there are also problems with the exchange of glucose, given the reception of Siofor. In general, better listen to the doctor, follow his recommendations and for accuracy try to consult another specialist, but always in person.
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Akami
Hello. I am 24 years old.There are problems with prolactin on the background of active pituitary gland (weight a little more, intermittent cycle, rashes on the face) also VSD (tachycardia). Approximately since February, moving to a new job (there is a lot of dust), a strong allergic reaction began, although I'm not allergic to life ... In the beginning, conjunctivitis, swelling and cracks in front of him, red spots and swelling in the face, neck, elbows, breasts . Take Tsetrin, Dezal (slightly reduced itching), Suprastin and Tavegil. Did not help. When the severe edema of the face and larynx with a violation of breathing began, she ran to the hospital. Nothing really said because. "atypical behavior of allergies and rashes, but within the dust and wool" (c), immediately injected Dexamethasone 12 ml + Glucose 10 ml, released on the next day. While resting at home the allergy did not make itself felt for a week (by the way, there were no animals on them at home), at work they went on a new one. Has passed or has taken place 3 mes already, to a ring Dexamethasone time in 5 days on symptomatology 8 ml, since 4 ml had no effect. At the moment I work without days off the 3rd month and already a month I see possible pobochki, maybe it's not them? Weakness, nausea, pain in the body, decreased libido, psychosis (frequent bad mood and swearing at the husband for no reason), easy weight gain as a stagnation of water,while in the toilet on the contrary I run very much (every hour), sometimes GI disorders, but rarely, arrhythmia of the heart with pain, headaches often. The last 2 times the input of Dex noted that the effect of the drug itself is weaker, it's terrible to take it now, but only it helps. Stronger to take is also scary, and refusal is fraught with a new swelling. Help, please advice, where to run I do not know and as long as there is no possibility; (
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admin
Akami, Your case is difficult to parse remotely, because some of these symptoms that have appeared recently may be manifestations of the endocrine problems described at the beginning of the question, so uniquely your specialists today are an endocrinologist (there is in each clinic) and an allergist.

Although with the allergist is just more clear, if there is harm - dust allergy and other production hazards, then staying on such work is slowly ruining your health. You yourself notice that a strong medicine Dexamethasone you began to help worse, then start increasing the dosage and so until you finally sit down on the hormone.And this is already fraught with the appearance of other symptoms (you can see for yourself how much of them are in the side effects). So the work should be changed to a cleaner one, there is no alternative.

Hormones should also be checked (if they did not do the analysis earlier) to make sure the validity of the pituitary conjecture is correct. Perhaps there will be a connection with the allergic reaction and the exchange of hormones of the adrenal glands or the pituitary gland (all of which are interrelated).
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Akami
Thanks for the quick response. At the endocrinologist I am observed from 18-19 years as have diagnosed prolactinemia (like correctly), the prolactin is strongly overestimated, last MRT has confirmed, that the pituitary body is active, here not a secret. Analyzes I hand over every six months, the rest is healthy like an ox, they said that it is amazing for our city.

I'm already thinking about the work, but I have to stand for 2-3 more months, so I'd like to somehow replace / remove Dex, but every 5 days the symptoms of an allergy go ((
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admin
Akami, 2-3 additional months for hormones you will not make the weather, especially with Dexamethasone you need to get off gradually.If you puncture it regularly and abruptly quit, withdrawal can develop, so take half the dose within a week or two, then even half the dose already received, and so on, until it is completely canceled.
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Tamara n.
My dad was prescribed a course of dexamethasone after a Gamma-Knife surgery in connection with the mts in the brain: 16 mg - 5d, 12mg - 5d, 8mg - 5d, 4mg - 5d, 2mg-5d, 1mg - 5dn. Today, high fever has risen 39, refuses to eat, dexamethasone has already pierced 4 times 4 mg, and the pill remains. Is it possible to interrupt the course of dexamethasone? pills will not drink, what can be the consequences of such cancellation?
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admin
Tamara n.Such cancellation is undesirable, it will be told to you by oncologists who observe your father. Because the tumor and metastases will provoke the development of inflammation and swelling in the brain, which, in turn, will worsen cerebral symptoms. I'm against it, but if it's really bad to take the medicine, you should consult your doctor about the dosage adjustments of Dexamethasone.
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- Cryptoanarchist -
How often can I repeat short-term 3-day courses without consequences for the body with exacerbations of COPD?
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admin
- Cryptoanarchist -, The question is incorrect. If the situation allows to do without the use of hormonal drugs - it is worth using this chance as much as possible. If you do not have hormones, then you'll have to use Dexamethasone or other similar drugs, because there is no alternative by and large. It is better to use as long as possible inhalant forms of hormones. And to calculate the moment when there will be a poisoning of the body is impossible, all people are different and the metabolism of hormones is different, plus the frequency of such injections. Some are able to endure them throughout life without significant negative consequences.
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alekseevna57
Hello! I have an intervertebral hernia in the cervical section. Osteochondrosis, arthritis and arthrosis. It was treated with chondroprotectors and various anti-inflammatory drugs alone in case of exacerbations. A month and a half ago my shoulder ached.The pain went from neck to collarbone and shoulder. The neurologist prescribed meadocals, arkoxia, pregabalin, phenibut, betamax. A sharp pain in the joint passed, but the hand began to grow dull. The muscle in the forearm contracts like in convulsions and the whole arm is numb. Now the neuropathologist has appointed dexamethasone, milgamma, trental, arthoxane, lezin escinate. All injections and droppers. Are all these medicines compatible? There are too many of them! I have chronic pancreatitis. Will my health stand?
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Olga
Hello! Tell me, please, whether it is necessary to make a gradual abolition of Dexamethasone after it was administered at 4 mg for two days?
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admin
alekseevna57, To me such treatment seems superfluous. Let's say that Dexamethasone is prescribed - a strong anti-inflammatory agent, then why designate Artoxane, which is a strong non-steroidal anti-inflammatory drug based on tenoxicam. You do not need the last medicine in this scheme. Or Dexamethasone should be removed, and Artoxan left. The rest of the drugs are logical and combined in one scheme of therapy.Although there is no specific diagnosis for a neurologist, here you have both anti-inflammatory drugs and vascular, we beat the areas immediately and all possible diseases. I think this approach is not professional enough. It's like taking antiviral drugs and antibiotics at once for a cold.
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admin
OlgaIf only two days can be canceled at the same time, withdrawal syndrome in this case should not be.
Visitors
Anita26
Hello. In April, 2017, I found on my feet a small red rash, similar to bites. I did not attach any importance to this. But very quickly this rash "crawled" up the legs. I went to the dermatologist, he immediately sent me to a rheumatologist, suggesting vasculitis. I (on the advice of a dermatologist) went to (as she said) the best rheumatologist in the city. I have previously passed a general blood test with ESR, rheumatoid, CRP, calcium, ALT, AST. Everything is normal, except for vitamin D (it is lowered), hemoglobin (also lowered), platelets are increased. Based on these analyzes and what I have in my entire life, and I'm 26 years old,there was stomatitis, herpes, I am light-skinned and quickly burn in the sun, I already have a temperature of 37.1-37.3 for several years without any apparent reasons, but I suspect on nervous grounds, the doctor diagnosed SLE. Has appointed or handed still to hand over analyzes: antibodies to double-stranded DNA, to nuclear antigens, an antinuclear factor, compliments С3, С4, circulating immune complexes, иммуноблот. I passed them and everything is negative, except that the rash has increased almost to the whole body: buttocks, thighs, hands. The doctor insists on the diagnosis of SLE. I underwent another 2 rheumatologists, they diagnosed hemorrhagic vasculitis, cutaneous form. I was prescribed 5 droppers of dexamethasone. 2 to 12 mg per 200 ml of saline and 3 to 8 mg per 100 ml of the drug. After these droppers, I was very ill for several days: my back ached and all the muscles, I could not sleep at night, it was very difficult to breathe, dryness in my mouth that I could not swallow. After 4 days, I felt better. The most interesting thing is that the rash went by itself, without treatment, even before the droppers, for 4 days, although it held for 2 months. Now for 3 days my back and muscles are hurting again. How do you think, can this still be SLE? And why the deterioration of health after the droppers? Thank you.
Administrators
admin
Anita26, I am more inclined to the diagnosis of vasculitis. Next, observe periodically from an adequate rheumatologist of those that you liked more and who prescribed you Dexamethasone. It is more likely that with anti-inflammatory treatment, it hit the nail, and how further developments will need to look in dynamics. Lupus with your words does not seem and specific diagnoses are quiet.

Back and muscles may well ache as a result of nervous overload, because they themselves are marked by a rise in temperature on the nerves, so you just have to get away from accentuation on your sores, it is possible that you simply do not have any organic substrate. You can wait another week, because Dexamethasone is withdrawn slowly. It is possible that the pains themselves will go away through this time. If is not present - it is possible to address to the neurologist, probably, it not the disease connected with a current status (a myositis, an osteochondrosis and others).
Guests
Марина 31 year
Hello. Tell me please. Has addressed to the doctor with pains in a loin, have appointed or nominated dexamethasone 2 ampules + lidocaine 1 ampoule intramusculary 5 days.After the first injection, everything went away. Has made 2 nyxes. Can I stop treatment? And it's scary to gain weight.
Administrators
admin
Марина 31 year, With the doctor treating it, because there is no specifics in the question - no diagnosis, no medical history. And then I say that you can, you cancel, and a week later, the relapse will come and again appoint 5 injections (total 7 injections). For 5 injections, you are unlikely to gain weight significantly, this side effect is observed, but indeed with prolonged use of Dexamethasone and in a small number of patients.
Guests
Vyacheslav Larionians
With the infringement of the sciatic nerve, the pains were unbearable or lying, nor could I sit, but it was not the same way to walk and it was not the same - the foot began to feel dumb and did not feel a big toe. We were advised to pierce three days once a day with a cocktail (lidocaine 1 ampoule, vitamin B12 2 ampoules, dexamethasone 1 ampoule). After the first injection, the pain was 90%, at the same time lay on the stretch (a smooth board with a slope of 30 degrees 20 cm above the board of the handle to hold, it is easy to do, while slightly strengthening the muscles of the vertebra and abdominal cavity by raising the legs).The pain has passed, now I lead a usual way of life, in the morning calmly washing myself, bending over the sink. Stretching I continue for 10-15 minutes a day, the most important thing is not to run the muscles on them the vertebra is held.
Guests
Shoira
I was diagnosed with Meniere's syndrome. The dexamethasone was prescribed according to the scheme: 1-2 days - 16 mg; 3-4 - 12 mg; 5-6 day - 8 mg; 7-8 day for 4 mg injected drip. Then 10 days for 2 tablets of prednisolone and other drugs. Today, the first day has been swept, 3-4 hours later such a broken state, a shiver inside and very painful joints of the legs.
Guests
Julia35
Hello. At me an osteochondrosis of a cervical department from the right party or side. Is it possible to prick dexamethasone? Will there be an effect?
Administrators
admin
Julia35, Remove inflammation and pain in the muscles and partly the joints of the spine with osteochondrosis Dexamethasone can and most patients feel this effect immediately. And then you need to work on yourself - gymnastics, physiotherapy, regular sanatorium treatment, the regime of work and rest. This disease is the result of human laziness and an incorrect mode of work.
Guests
Olga
Hello. I am athlete, constantly worried about Achilles with my tears, that it is impossible to train. Have advised dexamethasone in nyxes (5 injections in day). Will the Achilles tear disappear after such an application?
Guests
Alyona
Hello. My child was 3 years old when he became very ill. Bronchitis + angina and at night he suddenly gasped. A cough with strong rales began. My mother-in-law has honey. sister and took from a syringe processed throat dexamethasone. His throat swelled and rales passed.
Guests
Fadme
Hello. A daughter of 8 years old, never suffered from allergies. There was a cough, a cold. Began to treat (syrup, drops, compresses, anti-allergic). Everything passed. All drugs were canceled. It took 3-4 days, it was covered with spots, similar to hives. She gave diazolin, polysorb, and went to the ambulance, they injected dexamethasone and sent home. It became easier and the spots began to pass. The next day, a dry cough appeared at dinner. She gave me a cough, and by the evening the spots began to appear again. What to do?
Guests
Linda
With lymphoblastic leukemia, a course of Dexamethasone is prescribed for 21 days for a full dose and until day 35 for a decrease. I only know how the children suffer, the most difficult is the decline, sometimes scary to look at.
Administrators
admin
Olga, Inflammation will go away as long as the anti-inflammatory effect of Dexamethasone will work, but if you do not give rest for the right time (the traumatologist decides after the examination), then the decision is useless and everything will start anew in a short time. Plus hormones as far as I know are included in the list of doping for professional athletes (but in sports medicine and doping I'm not very competent, I can be mistaken).
Administrators
admin
Fadme, To search with the allergist the reason of an allergy, a possible circle of allergens, if it turns out, to eliminate their effect on the child's organism. Plus, a specialist will prescribe medication course or on a permanent basis, which will need to be taken. Perhaps after puberty or earlier the child will outgrow this allergy, at this age this sometimes happens.
Guests
Irina
Strong back problems. Osteochondrosis and coxarthrosis of the joint. The therapist doctor prescribed dexamethasone and v12 in one syringe. Three injections 1 time per day 4 mg dexamethasone and 500 v12. Said gives a good therapeutic effect. But alas ...
Visitors
Liubovkey
Diagnosis: Paresis of the trigeminal nerve. Do in a hospital dropper with Dexamethasone, according to my estimates, there are already 5 droppers. It looks like there will be 4 or 5 more droppers. My head aches, it throws me into a fever, some depressive stupor, and my stomach starts to ache. The attending doctor on my complaints says this all from the medicine, will pass. The doctor, and I am already very worried, what in my case will be the effect of lifting? And how gradually then move away from this drug? Advise, what then to accept to remove headaches and a depressive dullness. What medicine for pains in the stomach should I take, while still doing these droppers? And are they always gaining weight after the droppers with Dexamethasone?
Administrators
admin
Liubovkey, Strange at you hospital, doctors should tell possible or probable effects of medicines applied in treatment.Pain in the stomach, if it is an inflammation of a medicinal gastritis caused by Dexamethasone, is best removed by blockers of the proton pump (omeprazole, esomeprazole and their commercial counterparts), although it is the doctor's task to prescribe these drugs. The withdrawal syndrome should also be taken into account in the course of therapy, and the side effects caused by the use of drugs pass within a month (usually earlier) after the completion of the Dexamethasone course.
Visitors
Valera
Valery is 57 years old. I completed 3 courses of chemotherapy. Dexamethasone was administered to the dropper. The chemistry was over. Headaches began. It hurts day and night. The dose is not indicated on the discharge sheet. Do not get to the doctor. What should I do?
Administrators
admin
Valera, Measure the pressure and temperature, consult a neurologist for possible headaches from cervical osteochondrosis. If everything is normal, then wait until the end effect of dexamethasone is over (sometimes negative symptoms persist until 1months after the end of treatment).
Guests
Timothy
I have retinal edema, the doctor prescribed 8 ml intravenously and 1 ml in the eye of dexamethasone, and I began to lose my eyesight sharply, the pressure drops 103/60 and 80/60, although 6 months ago I immediately had swelling at the same appointment, the pressure was also very low. I was so hoping that the dex would help me, but alas.
Visitors
capitol
The daughter is pregnant 33-34 weeks. In the analysis of urine, a protein was found. Have appointed dexamethasone. Will this affect the child and how can it affect the daughter?
Administrators
admin
capitol, All effects of the use of Dexamethasone in the early and late stages of pregnancy are in the instructions. How does the body of the child and your daughter know exactly how to take the medicine, therefore, a risk assessment by the treating physician is necessary (can he choose something safer from the available arsenal of medicines on the market)?
Visitors
Nikodim
Doctor, hello. At me for a long time a peptic ulcer 12PK, herpes, years 2 a tachycardia attacks and there are jumps of pressure.I myself am quite full, sugar is on the limit at gauging. 3 months ago after the next attack of a tachycardia and jump of pressure "has caught" a ring (noise) in both ears. Surdology diagnosed neurosensory hearing loss of 1 degree and prescribed droppers with dexamethasone - 16-14-12-10-8 mg. in a hospital. Do you think it is worth risking a possible loss of health - an aggravation of an ulcer, herpes, obesity, diabetes? Will there be a benefit in treating tinnitus? Thank you.
Administrators
admin
Nikodim, According to the description of the problem, it seems that the cause of noise in the ears is vascular, perhaps anatomically convoluted arteries of the vessels of the inner ear, as the pressure increases there are vortexes that cause noise, and in this situation the use of the hormone will be useless. But you have a doctor and you need to follow his recommendations. With noise in the ears is always difficult, especially with causes and treatment.

With gastritis and ulcer, dexamethasone prescription is possible, but it is necessary to take protective medications, the standard is the appointment of proton pump inhibitors (omeprazole, rabeprazole and others).
Guests
Ekaterina Demyanchuk
I have a 100% allergic rhinitis. It's a terrible thing. Without drops I do not go, I hardly breathe, I sleep, waking up 3-4 times a night to dip my nose. We went to the LOR and he prescribed 7 injections of dexamethasone. If it were not for them, I would not know what it is, free to breathe. Very good result. I noticed no side effects. Therefore, I put this drug a huge +

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