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Trental - instructions for use, reviews, analogs and formulations (100 mg and 400 mg tablets, injections in 5 ml ampoules) medicines for the treatment of circulatory disorders in adults, children and pregnancy »Page 2

Trental - instructions for use, ratings, analogs and release forms (tablets of 100 mg and 400 mg injections in ampoules 5 ml) drugs for treatment of circulatory disorders in adults, children and pregnant

In this article, you can read the instructions for using the drug Trental. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Trental in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Trental with available structural analogues. Use for the treatment of circulatory disorders and trophic disorders in adults, children, as well as in pregnancy and lactation.

 

Trental - vasodilating drug, improves microcirculation, angioprotector, xanthine derivative. Trental improves the rheological properties of blood (fluidity) by affecting the pathologically altered erythrocyte deformability, inhibiting platelet aggregation and decreasing the increased blood viscosity. Improves microcirculation in areas of impaired blood circulation.

 

The mechanism of action of Pentoxifylline (the active substance of the drug Trental) is associated with inhibition of phosphodiesterase and the accumulation of cAMP in the cells of the smooth muscles of blood vessels and blood cells.

 

Providing a weak myotropic vasodilating effect, pentoxifylline somewhat reduces OPSS and slightly dilates the coronary vessels.

 

Treatment with Trental leads to an improvement in the symptoms of cerebral circulation disorders.

 

The success of treatment in the occlusal lesion of peripheral arteries (for example, intermittent claudication) is manifested in the elongation of the walking distance, the elimination of night cramps in the gastrocnemius muscles and the disappearance of pain at rest.

 

Pharmacokinetics

 

After oral administration, pentoxifylline is almost completely absorbed from the digestive tract.After almost complete absorption, pentoxifylline is metabolized. More than 90% is excreted by the kidneys in the form of unconjugated water-soluble metabolites.

 

Indications

  • peripheral circulatory disorders of atherosclerotic origin (eg, intermittent claudication), diabetic angiopathy, trophic disorders (eg, shin ulcers, gangrene);
  • disorders of cerebral circulation (consequences of cerebral atherosclerosis, such as impaired concentration, dizziness, memory impairment), ischemic and post-insult conditions;
  • frostbite;
  • postthrombotic syndrome;
  • circulatory disorders in the retina and choroid of the eye;
  • otosclerosis, degenerative changes on the background of the pathology of the vessels of the inner ear and hearing loss.

 

Forms of release

 

Tablets of 100 mg.

 

Tablets 400 mg (Trental 400).

 

Concentrate for the preparation of a solution for infusions (injections in ampoules) of 5 ml.

 

Instructions for use and dosage

 

Pills

 

The dose is set individually, according to the characteristics of the patient.

 

The drug is prescribed by mouth for 100 mg (1 tablet) 3 times a day, followed by a gradual increase in the dose to 200 mg 2-3 times a day. The maximum single dose is 400 mg. The maximum daily dose is 1200 mg.Tablets should be swallowed whole during or immediately after meals, with plenty of water.

 

In patients with impaired renal function (QC less than 30 ml / min), the dose should be reduced to 1-2 tablets per day.

 

In patients with severe impairment of liver function, a dose reduction should be taken taking into account the individual tolerability of the drug.

 

In patients with low blood pressure, as well as in people at risk because of the possible reduction in blood pressure (patients with severe CAD or with hemodynamically significant stenosis of the brain vessels), treatment can be initiated in small doses, in which case the dose should be increased gradually.

 

Ampoules

 

The dose and schedule of application are determined by the severity of circulatory disorders, and also taking into account the individual drug tolerance and patient characteristics.

 

The drug is administered intravenously in the form of infusions 2 times a day, in the morning and in the afternoon. A single dose (per 1 infusion) is 200 mg of pentoxifylline (2 ampoules of 5 ml) or 300 mg of pentoxifylline (3 ampoules of 5 ml) in 250 ml or 500 ml of a 0.9% solution of sodium chloride or Ringer's solution.

 

Compatibility with other infusion solutions should be tested separately; Only transparent solutions can be used.A dose of 100 mg should be administered for at least 60 minutes. Depending on the concomitant diseases (heart failure), there may be a need to reduce the amount administered. In such cases it is recommended to use a special infuser for controlled infusion.

 

After daily infusion, 2 tablets of Trental 400 may be prescribed. If 2 infusions are separated by a longer interval, then 1 tablet of Trental 400 from the additionally assigned two can be taken earlier (at about noon).

 

If, due to clinical conditions, the implementation of intravenous infusion is possible only once a day, additionally after it, 3 tablets of Trental 400 (2 tablets at noon and 1 tablet in the evening) can be prescribed.

 

Prolonged intravenous infusion of Trental for 24 hours is indicated in more severe cases, especially in patients with severe pain at rest, with gangrene or trophic ulcers (3-4 stages according to Fontaine).

 

The dose of Trental for parenteral administration within 24 hours, as a rule, should not exceed 1200 mg, with the individual dose can be calculated by the formula: 0.6 mg per kg of body per hour. The daily dose of the drug, calculated in this way,will make up for a patient with a body weight of 70 kg 1000 mg, for a patient with a body weight of 80 kg - 1150 mg.

 

Side effect

  • headache;
  • dizziness;
  • anxiety;
  • sleep disorders;
  • convulsions;
  • aseptic meningitis;
  • hyperemia of the facial skin;
  • blood rushes to the skin of the face and upper chest;
  • edema;
  • increased brittleness of nails;
  • anorexia;
  • intestinal atony;
  • feeling of pressure and overflow in the area of ​​the stomach;
  • nausea, vomiting;
  • diarrhea;
  • tachycardia;
  • arrhythmia;
  • heartache;
  • a decrease in blood pressure;
  • leukopenia, thrombocytopenia, pancytopenia;
  • bleeding from the vessels of the skin, mucous membranes, stomach, intestines;
  • impaired vision;
  • itching;
  • hyperemia of the skin;
  • hives;
  • angioedema;
  • anaphylactic shock.

 

Contraindications

  • massive bleeding;
  • extensive hemorrhage in the retina of the eye;
  • hemorrhage in the brain;
  • acute myocardial infarction;
  • porphyria;
  • age to 18 years;
  • pregnancy;
  • lactation period (breastfeeding);
  • hypersensitivity to the components of the drug;
  • hypersensitivity to other methylxanthines.

 

For intravenous administration (additionally) - arrhythmias, expressed atherosclerosis of the coronary or cerebral arteries, uncontrolled arterial hypotension.

 

Application in pregnancy and lactation

 

The drug is contraindicated for use in pregnancy and lactation (breastfeeding).

 

Use in children

 

Trental is contraindicated in children and adolescents under the age of 18 years (efficacy and safety of use not proven).

 

special instructions

 

Treatment should be carried out under the control of blood pressure.

 

In patients with diabetes mellitus taking hypoglycemic drugs, the administration of the drug in high doses can cause severe hypoglycemia (dose adjustment is required).

 

At appointment simultaneously with anticoagulants it is necessary to watch carefully indicators of a coagulating system of a blood.

 

In patients who have recently undergone surgical intervention, systematic monitoring of hemoglobin and hematocrit levels is necessary, the administered dose should be reduced in patients with low and unstable blood pressure.

 

In elderly people, a dose reduction may be required (increased bioavailability and reduced rate of excretion).

 

Smoking can reduce the therapeutic effectiveness of the drug.

 

Use in Pediatrics

 

The safety and efficacy of Trental in children are not well understood.

 

Drug Interactions

 

Pentoxifylline is able to enhance the effect of drugs that lower blood pressure (ACE inhibitors, nitrates).

 

Trental can enhance the effect of drugs that affect the blood coagulation system (indirect and direct anticoagulants, thrombolytics), antibiotics (including cephalosporins).

 

Cimetidine increases the concentration of pentoxifylline in the plasma (risk of side effects).

 

Co-administration with other xanthines can lead to excessive nervous excitement.

 

It is possible to increase the hypoglycemic action of insulin or oral hypoglycemic agents when taking Trental (an increased risk of developing hypoglycemia). If combined therapy is required, strict monitoring of the patients' condition is required.

 

In some patients, simultaneous administration of pentoxifylline and theophylline may lead to an increase in the concentration of theophylline in the blood plasma. This can lead to an increase or increase in the side effect associated with theophylline.

 

Analogues of the drug Trental

 

Structural analogs for the active substance:

  • Agapurin;
  • Agapurin retard;
  • Arbiflex;
  • Vazonite;
  • Pentamon;
  • Pentylin;
  • Pentylin forte;
  • Pentohexal;
  • Pentoxifylline;
  • Pentomer;
  • Radomine;
  • Ralofect;
  • Trenpental;
  • Flexitale.

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Reviews (213):
Administrators
admin
IrinaAnd the glue label with the hologram on the package was? And it is more like a banal larceny by a pharmacist of an expensive imported medicine, which recently happens often. Especially it concerns medicines that can be easily opened and quietly closed back. And as for forgery, only certificates for the party can serve as a basis for the fact that the medicines are real, all the rest can not be such. Documents should be asked from pharmacists at sales points.
Guests
Irina
The shortcut was there and it was not damaged. Thanks for the answer.
Visitors
Alekseich
Hello. After taking Trental 100 mg (dosage: morning and evening for one tablet), after 15 days, I noticed a glitch in my eyes - blinking, clouding, my head hurts in the evening. Now the 23rd day of admission. Tell me, please, if I stop taking the drug, will my initial vision return to me? Or...
Administrators
admin
AlekseichIf the cause of your visual disturbances in taking Trental, then after the drug is discontinued everything is normalized within a week. If the cause could be vascular phenomena (as I understand Trental from this and appointed), the cancellation will not contribute to normalization. So on this issue, consult a doctor who prescribes treatment for you.
Guests
Vladimir77
Hello! I had an operation - stitched the rills of the Achilles. Three months passed after her, I walk and limp, but there was pain (not in the area of ​​the seam, but from the little finger to the heel) - the neurologist prescribed injections: Prozerin, Thiamine, Nicotinic acid and prescribed Trental 400 mg. (1 tablet 2 times a day, take 2 weeks). The cost of this drug is very high.Advise, please, a cheaper analogue, which can be purchased in Moscow pharmacies.
Administrators
admin
Vladimir77, Cheap domestic analogue of Trental is Pentoxifylline. The truth about the replacement is still to consult a doctor who prescribes treatment, since this doctor is responsible for the results of your treatment.
Guests
Vladimir77
Hello again! Thanks for the answer, the doctor allowed me to use Pentoxifylline. Prompt, please, it can be combined with reception of a preparation - Najz?
Guests
Fatima
Hello! The doctor prescribed Trental droppers with baralgin, dexamethasone and B12. After the first dropper, spasmodic pains in the stomach, sensations of heaviness and discomfort began. Trental is appointed for the diagnosis of "Knee Osteoarthritis"!
Administrators
admin
Vladimir77, Read the rules and register. Sometimes I answer unregistered visitors, as it was with your case, but the rules must be observed.And if the question is already about Pentoxifylline, not Trental, then it will be more correct to ask him for Pentoxifylline.
Guests
Olga
Hello! I was prescribed trental in sarcoidosis. Is this drug shown for this diagnosis? The instructions are not spelled out.
Administrators
admin
OlgaThe answer to the question about the use of Trental in sarcoidosis I already gave. Look above and using the page search.
Guests
Tatyana
Hello. At my husband a diabetes 2 type + an arterial hypertonia 2 risk. Every year he goes to the hospital to prevent and maintain his health. And this time he was prescribed treatment: 5.0 trental + analgin 50% 2.0 + sodium chloride 0.9% 200.0 w / w, piracetam 10 in / in, Riboxin10.0 + vitamin C 4.0 + potassium chloride 7.45% 10.0 + sodium chloride 0.9% 200.0 in / in, diclobber 3.0 v / m, vitamin B1-B6 1.0 w / m h / d, berlipril 10 mg in the morning, trombo acc 50 mg n / n, 2.5 mg adend in the morning (from the extract). Then he started complaining that 3 middle toes began to grow dumb (until the hospital was not there). Also, they were assigned to continue treatment at home: in addition to taking mannil and the syophore, they prescribed berlipril 10 mg for 1t in the morning, trombo-ass 75 mg n /trental 400 mg to 1 t * 3 r per day, vasilip 10 mg 1 t in the evening. Trental and Vazilip began to drink not immediately as it was discharged, but for a week. And a couple of days later complains again that not only his fingers, but also his leg became dumb. According to the description trental should not give such a side effect, he also for improving blood circulation. Especially the memory began to fail a bit. After reading the instructions, I on the contrary thought correctly assigned trental. Or maybe it's a vasilip, or the leg is numb in the medication complex. Maybe such a set of medicines is a bust. Some questions and guesses. What do you advise? To the doctor does not want to go, there is no trust. Thanks in advance.
Administrators
admin
Tatyana, According to your description of the problem, I see that the shortage of drugs is more likely and my husband develops neuropathy, which leads to numbness of the fingers and limbs. This is serious. Therefore, Trental is good, but perhaps your husband shows the appointment of more powerful drugs or hospitalization in a hospital. Maybe I'm wrong and this is such an individual reaction to Trental or Vasilip (judging by the fact that earlier your husband did not take these drugs), but you can only understand this by canceling these drugs one by one for a week.Independently, I do not recommend this to your husband, it is quite possible that his time is running out, no matter how late.
Guests
Olesya
Good afternoon. My back became very sore. The neurologist has appointed trentalum on 400 mg 2 times a day. I drink the third day. I stopped sleeping at night, constantly lacking air, I can not breathe. On the first day my head ached heavily. There was a nausea. Given the fact that it became difficult to breathe, I think that this is from taking the drug.
Visitors
F.Andrey
Hello. At me an atherosclerosis + varices, have registered trental 200mg 3 r / d and venarus 2 r / d. Tell me, how are they better taken together or somehow spread over time? Thank you.
Administrators
admin
F.Andrey, Trental and Venarus can be taken together. These drugs are well combined and complement each other's effects. According to the instructions and experience of using negative side effects when taking these drugs together should not be.
Guests
Larisa Sap
For treatment of PTF (posttraumatic phlebotrombosis) trental in droppers was prescribed: the second dropper went vomiting, on the fifth - high fever and edema, tachycardia. The treatment was extended to 9 droppers.
Visitors
Igor Vladimirovich
Hello! To me today the doctor has diagnosed: "an endarteritis of the lower extremity of the right leg", and thus has written out medicines "Trental-400 and ointment Amelotex". I started taking pills and ointment. I read the most terrible about this diagnosis on the Internet, it even becomes bad. Is it possible to pierce the injections together with the pills? My leg hurts very much, I limp a bit when walking. In a calm state tolerant .... Thank you in advance.
Administrators
admin
Igor Vladimirovich, Follow the recommendations of the attending physician and do not mix the taking of tablets and at the same time put injections of the same drug. If the treatment is not enough, the doctor will prescribe the injections themselves or replace them with another drug.
Visitors
Igor Vladimirovich
Thank you. Tell me, can Trental 400 and Amelotex cure this disease? With all that, I also smoke, I do not use alcohol.
Administrators
admin
Igor Vladimirovich, You can understand this only after being treated. Everyone has different stages of this disease, one and only Trental can help, and some are cured by various treatment regimens (hormones, etc.) right up to the operation of vascular plastic surgery. But with smoking will have to be tied up for ever, this pernicious habit is the most important enemy of blood vessels and contributes to an even greater spasm. In your treatment regimen, you can still add physiotherapy and antispasmodics (nicotinic acid helps and it is cheap), but you will ask the attending physician about this.
Visitors
Igor Vladimirovich
Thanks for the help.
Guests
Tatyana
Creepy drug! Look at how many side effects he has! Is it possible in our time to think of anything else to improve microcirculation.They assigned me a drip. They dripped 30 ml. I felt sick. More dripping did not. The doctor said that this drug is heavy and many people suffer poorly.
Visitors
Alex ..
Hello! Have appointed a preparation from a fungus of fingernails or nails, in an instruction about it or him word. Maybe it's time for my dermatologist to take it myself? It seems to be good for the brain. Thank you!
Administrators
admin
Alex ..If Trental is prescribed to you in combination with antifungal agents, then there is a sense. With mycosis, vitamins are also prescribed, because all this in a complex helps to increase blood circulation in the limbs and improve metabolic processes in the skin. If only one Trental is appointed, then yes, something is wrong with the doctor.
Visitors
luna
Hello! My grandmother has bronchial asthma, recently the top of her head began to hurt, a familiar doctor advised trental 100 in the table. and ceraxone in 2 ml syrup without dilution in water. Can I combine them? So, after receiving on the third day, her breathing became aggravated (often using Ventolin, and for the night of Teotard), the pressure dropped 120/60 and the heart beat - 101 beats.The headache subsided, but occasionally it hurts, but not painfully.
Administrators
admin
luna, Of all the described, to cause dyspnea this set of drugs could not, because they can all combine and according to the instruction of negative side effects when a joint admission should not be. But the quickening of the pulse and the decrease in pressure when taking Trental can, as an adverse reaction. So please contact the doctor again to see what can be changed in the treatment regimen. Perhaps, the reaction described in the question is not at all on drugs, but it shows itself your grandmother's bronchial asthma.
Visitors
elen izmailova
Hello, I have diffuse alopecia (hair loss) and a common osteochondrosis 1-12 vertebrae. The dermatologist prescribed Trental 100 mg 3 r \ day to improve blood microcirculation in the scalp for 21 days. Prompt, whether the preparation is correctly appointed or nominated and whether such duration of reception of a preparation will be enough for achievement of effect. And among the side effects of trental there is such a nuisance as anaphylactic shock, tell me how often it happens, is there any statistics of the occurrence of this side effect?
Administrators
admin
elen izmailova, Trental can be used for a duration of 2 weeks, so that the doctor is formally right, the rest is decided by the specialist. It seems to me that the period is too short, there will be little or no improvement in 3 weeks there, although this is probably only the beginning of the course of treatment.

There is no specific statistics on the probability and frequency of occurrence of any side effect for Trental. In this case, the appointment is based on previous cases of allergic reaction in response to taking medications. If there are already allergies to Trental, then it is worth notifying the doctor about this for changing the therapy scheme.
Guests
zinaide
While I can not say nothing about it, I'm worried about the terrible itching of my ankle. In addition trentala I accept eskuzan and detraleks.
Guests
George
The overwhelming majority of reviews that the condition when taking the bad, and many - very bad ... And to understand the real "plus" of taking Trental to us, the patients, it is difficult. So far, I have only taken a dropper three times, and today for 4 times, until I went - the state is disgusting.Is there nothing more perfect in the world for the treatment of blood vessels? With a minimum of side effects. If so, what medicine? Yet it is difficult to be treated when you become worse after starting treatment ...
Also I accept: noliprel 2.5, aspirin-cardio 100, lypimar 10, and in addition to Trental: a dropper of L-lysine escinate, mildronate IV, actovegin in / m, detralex tablets per 1/2 r per day.
Thank you
Administrators
admin
GeorgeThere are plenty of medications for the treatment of blood vessels, the whole issue is what we treat and why. Most appointments of doctors from the category of "detach", like we will appoint this useless drug in this situation and see the effect. Therefore, before asking you need not only a list of drugs taken, but also a medical history, and the results of research and analysis. Therefore, I try to give advice on preparations, and it is not possible to prescribe remotely the therapy scheme in most cases. Chushes will be prescribed to you at an admission of mediocre doctors too.
Guests
Irina
Tell me, please, can I take noliprel with trental? Thank you. Excuse me.
Guests
Tatyana
Hello. I have sarcoidosis of the lungs. They prescribed Trental, a course of 3 months, 400 mg - 2 tablets 2 r per day. The pressure is 90-60. After taking - weakness, nausea, dizziness, pressure decreases, feet wadded. I drink the 3rd week. I can not work in this state. Often I just fall asleep after the pills. The disease is progressing.
Administrators
admin
Irina, It is possible to share the drugs mentioned in the question. Trental increases the effect of medications that lower blood pressure, so you may need to adjust the dose of Noliprel and take pressure control.
Guests
Nina Alexandrovna
Tired of the night leg cramps. Orthopedist prescribed trental. The cramps stopped. Drank the course and three months there was no seizures, but again it happened again.
Visitors
Olga-Victoria
Hello! I read all the comments on the prescription of this drug, but I did not find the answer to my question.
To me of 45 years, an osteochondrosis p \ kresttsovogo a department, a scoliosis of a thoracal department and an osteochondrosis cervical (this is the conclusion of the neurologist).
Joints hurt. One rheumatologist diagnosed - polyostoarthrosis st.2 - recommended: walking, swimming pool, alflutop 2r. per year for 20 injections.
Another rheumatologist diagnosed Reynaud's syndrome, the prolapse of the mitral valve is hemodynamically insignificant. Polyartralgia. Recommended: trental 0.1 to 1 point. 2-3 r. per day - 1-2 months. (repeat 2 times a year) or nikoshpan, or halidor ..
I have low pressure - my working 90-54.
And the question itself - I have in the area of ​​the isthmus an intramural-subserous myoma node measuring 45 * 38 mm. Is it possible to apply this drug (trental) in myoma?
Thank you.
Administrators
admin
Olga-VictoriaWhen using Trental's myoma, it is acceptable, this diagnosis is not a contraindication to taking the drug. But the problem with you so far with a clear diagnosis, because different doctors put different diagnoses, respectively, and approaches to therapy indicated in the issue of diseases are different. It is worth to trust one of them or get a consultation of a third specialist, because I do not see any unambiguousness in the issue of diagnosis and treatment.
Guests
Tatyana
Hello! Prompt please I had a neuropathy of a fibular nerve. The doctor prescribed nicotinic acid intravenously 5 ml, milgamma. It was pierced, and numbness of fingers remains, have appointed or nominated 10 more days to drink pentoksifillin 0,4 on 1 2 r / day. Will this medicine help?
Administrators
admin
Tatyana, Trental contains in its composition the active substance pentoxifylline, so that it can be used in your treatment regimen. This is an expensive brand Pentoxifylline.

Numbness in neuropathies can take a long time, even with adequate medication. Use for this purpose all of the above means, plus you can apply Glycine, other preparations of B vitamins (you have already used Milgammu). A single-valued scheme that would help 100% of all patients at present is not.
Guests
Rassokhina Galina
To me the preparation trental helps or assists from night calf convulsions though in the instruction about it it is not written. I wrote to his neurologist, I read the instruction on the Internet - I drank one 400 mg tablet and slept calmly today winked
Visitors
Maria L
Saw Trental 3 times a day for one tablet. The drug did not like. Maybe it's effective, but the side-effects from it are terrible. My doctor prescribed it for severe headaches, to improve blood circulation. Headaches after taking, only intensified. In addition, the pressure dropped very badly and there was a slight tremor in his hands. She drank 3 days and left, it is impossible to endure such pobochki.
Visitors
Astrahanceva
Hello! I really need advice on the drug trental. Half a year ago I was in hospital with symptoms of numbness of the left part of the body, various tingling sensations along the body, a feeling of constant anxiety, weakness, back pain in the lumbar region, and not frequent headaches. In 2012, fell from the 4th floor, was OCDM and a fracture of 3 vertebrae of the lumbar region. Having made an MRI of the head, cervical, thoracic and lumbar region, I found: light internal hydrocephalus, osteochondrosis of the thoracic and cervical region, venous stasis in the spine, and multiple Schmorl hernias throughout the spine. The doctor said that my symptoms are most likely due to this venous congestion,and prescribed trental 100 for a month 2 times a day. Now I have severe headaches in the forehead area, and back pain. Tell me please, maybe you should once again drink this course trental? Since there is no communication with the doctor.
Administrators
admin
Astrahanceva, That is, the course of Trental, as I understand it, passed six months ago, immediately after the trauma and examinations? If so, then it is perfectly permissible to drink the course of Trental. Only 1 tablet of Trental 100 2 times a day will not be enough, even according to the instructions the initial dose of 1 tablet 3 times a day, and then more. Then to the neurologist all the same it is necessary to address, probably in course of time something has exchanged in a picture of your disease.
Visitors
Natalia1984
Hello. My child (6 years old) suffered an infection of the urinary system, with severe hematuria. Lied in the hospital for a month. Now they were discharged home, but they said to continue the treatment with pills for 3 more months, because up to the end we have not recovered yet. So one of the prescribed medications is trental 100. Prior to that, the hospital drank quarantil (the doctor explained that she had replaced him with a trental, because he is better, but he is not in the hospital).The child was tranquilized by a reaction in the form of dizziness and nausea, but not for long, then passes. Our doctor went on vacation, so I think what to do - cancel it or maybe reduce the dose?
Administrators
admin
Natalia1984, I do not really know the situation, plus I do not see a child, but if the strength of these symptoms is not great, then it is possible to continue the prescribed treatment, subsequently contacting your doctor. In the hospital, the child was given Kurantil, and how did he react to this medicine? The reaction might not have to be because these drugs are indirect analogs to the active substance and here the doctor's task is to decide whether to take the prescribed medicine and its effect on the child's body.
Visitors
Anns
I have sarcoidosis. I pass or take place a course of treatment trentalom and vitamin A. Whether it is possible at reception trentala to do or make nyxes with diclofenac?
Administrators
admin
Anns, It is possible, but it is necessary to be careful, as the risk of bleeding increases.If there were episodes of bleeding from the gastrointestinal tract or a diagnosed stomach or duodenal ulcer, ulcerative colitis, then it is better not to prescribe such a combination at all.
Visitors
lyahov.1978
Good afternoon! To the mum of 70 years, the neurologist has appointed or nominated trental 400 mg 3 r / d. But somewhere my mother heard a rumor that trental strongly influences vision, supposedly people are blinded from him. Help explain to mom that this is not true, otherwise she refuses to accept it?
Administrators
admin
lyahov.1978, Offer her to live with her neurology, because I have such rumors I can find about a hundred drugs. On the other hand, if the individual patient has an individual drug intolerance (one case per million) and he really will go blind, why take the extra on himself. There is an instruction, there are indications, side effects and contraindications - the rest is the art of the doctor who prescribed the medicine and the patient's will to be healthy.
Guests
infection
Good afternoon. Has appointed or nominated the neuropathologist trental 100 3 times a day on 2 tab. I have been drinking for 5 days, and with every reception I feel sick and can not eat.
Guests
IRINA
Tell me, please, is it possible for a disabled person to submit Trental with a severe form of cerebral palsy? Very cold feet, after walking in a stroller along the street, feet and calves are icy. Constantly accepts Depakin chrono 300. Thankful in advance.
Administrators
admin
IRINAYou can give Trental, I like the response of patients with similar problems to nicotinic acid. Doctors in any case, the patient should be shown, because the causes of circulatory disorders of the limbs are different. Suddenly there is a blockage of blood vessels, and we will stuff the patient with quite different tablets.

With Depakin chrono 300 combined and Trental, and nicotinic acid. There should be no negative side effects according to the instructions.
Visitors
yabizins
Hello! At me a necrosis of a kidney 2 ст and a chronic pyelonephritis. The doctor appointed trental. Do I need to take it? The annotation says nothing about the kidneys.
Administrators
admin
yabizins, But it is said about the violations of peripheral blood circulation, for which you, most likely, and was prescribed the drug Trental.By improving blood flow in necrotic tissues, it is possible to reduce the focus of tissue death in the affected organ.
Administrators
admin
Feedback from the site visitor Olga moved to the required section:
The child (3 years) was diagnosed with Kawasaki syndrome. He is receiving treatment at the regional children's hospital in Nizhny Novgorod. Trental was prescribed, with intravenous administration the child became ill: weakness, vomiting. Intravenous injection was replaced with tablets, the child does not eat anything, periodically vomits.
Visitors
Yana84
Good afternoon! To me have appointed or nominated trental in krio the report on 100 mg 2 times a day. I so understand for prophylaxis. The pressure at me lowered 100 on 60. Me became sick and at the same time strong weakness, then passes and so a couple of times a day. Can I continue taking pills?
Administrators
admin
Yana84It is worth talking about this moment with the attending physician, because with uncontrolled hypotension, the use of Trental is contraindicated and this can be dangerous.Although this is an indication for intravenous administration of the drug, it is nevertheless necessary to assess the severity of the side effect and the need for further therapy. Remotely this time can not be disassembled.
Visitors
ann963
Hello! I have neuropathy of the ulnar nerve. Now I'm on a hirudotherapy course. The first two times the bleeding was weak, and after the third the blood flows abundantly. On the eve of the appointment of a neurologist, I started taking trentalum at a dose of 100 mg 3 r./d. So far, only 3 tablets have been taken. Could the trental could provoke an increase in bleeding, and can it be combined with hirudotherapy?

In addition, I have low blood pressure - 60 to 90. I was already prescribed trental in the summer, I hardly drank two weeks, as I did not tolerate it well (weakness, dizziness, sleep disturbances). But the doctor insists that I need this drug. Maybe there are some analogues that do not cause such a decrease in pressure?
Administrators
admin
ann963I would not combine Hirudotherapy with taking the drug Trental.It is necessary to choose one thing, and after passing the first course of treatment to pass the second course, as treatment is course, not permanent.

About Trental with neuropathy, you can try Xanthlin tablets nicotinate or beat intramuscularly with Emoxipine. Probably, something from these analogues on the pharmacological group will allow to maintain the blood flow of peripheral vessels and not cause a strong decrease in blood pressure. All other analogs will be derivatives of pentoxifylline (Trental's active substance) and will most likely produce a similar effect. Treatment should be coordinated with your doctor.
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Nika
Good afternoon! Recently passed prophylactic medical examination. His arms and legs go numb at night and in the daytime, hemoglobin 169, his head is often dizzy, and the general state of permanent weakness. The doctor wrote down the symptoms, did not appoint anything. I understand that on the Internet to look for treatment is useless, but can tell to which doctor to turn and what drugs can be taken?
Administrators
admin
Nika, According to the described symptoms, your doctor is a neurologist.It is necessary to conduct a survey of the conducting nervous system, the brain. Measure a couple of days of pressure in the morning and in the evening and write down, in addition to help the doctor determine the diagnosis. If peripheral blood flow is reduced, Trental may be prescribed and its analogs.
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Viktorija Zlobina
Good evening! An ophthalmologist has appointed Trental 400 twice a day, I have glaucoma, but regardless of this, sometimes there is blurred vision, the doctor believes that this is from the blood vessels. There is also type 2 diabetes, I take Galvus 50 twice a day, I have not noticed hypoglycemia, I have already taken the 6th day, my head is very sore, and the usual pressure for me is 155/95. Should I continue to take Trental? Will the headache go away?
Administrators
admin
Viktorija Zlobina, Side effects in the form of headaches when taking Trental it can be observed. The question is solved either by decreasing the dosage, or by replacing the drug with other medications. As a substitute, given the situation described, Fezam, Nicergoline and their commercial counterparts can be used. It is better to consult with the attending physician on this issue, taking into account the existing concomitant diseases.
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Elena Alekseevna
Hello. Can I take trental after a micro stroke?
Administrators
admin
Elena Alekseevna, With this issue only internally to the neurologist, because hemorrhagic stroke is a contraindication to taking the drug Trental, and you hardly know the form of this disease and at what stage of recovery is the patient.
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katerinakleo
I have scleroderma. 10 days I took in the hospital Xantinol nicotinate. Can I now drink Trental 100?
Administrators
admin
katerinakleoThe drugs mentioned in the question are acceptable for long courses. If Trental is recommended by the attending physician, you can take it after the Xanthine course.
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Irinka
Hello. I have a hernia and protrusion of the lumbosacral section. The neurologist has appointed trental 100 mg 3 times a day for a month.Can I take diclofenac with a severe pain syndrome? (the doctor did not appoint anything else)
Administrators
admin
Irinka, C Diclofenac Trental is combined normally and according to the instruction of additional negative effects as a result of using such a combination should not be. However, there is an indication that the simultaneous use of Trental with Ketorolac and Meloxicam (also non-steroidal anti-inflammatory drugs like Diclofenac) may increase the risk of developing gastrointestinal bleeding, so it's best not to lose your vigilance and monitor your health when using such combinations.
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kiskins
Hello. Tell me, please, my husband was diagnosed with arterial hypertension, he was prescribed treatment: vimloset in the morning, torvacard, physiothese in the evening and trental 100 three times a day for one tablet. I read the instruction to the trental, it also has an antihypertensive effect, will not there be a bust from so many drugs that lower the pressure?
Administrators
admin
kiskins, Trental to your husband is registered as an angioprotector and means improving microcirculation in blood vessels. Reducing pressure is not an option, but a possible effect. If previously the patient did not take any medication to reduce the pressure, then the scheme is quite acceptable.

Statin (Thorvakard is appointed to your husband) in the light of recent scientific doubts, I do not much favor, but if there is slagging of the vessels with plaques and increased cholesterol, then this medication can not be dispensed with.

Further in the course of treatment, this scheme will be adjusted (or will not be) based on the result of achieving the necessary hemodynamic parameters (values ​​of AD, cholesterol, etc.).
Guests
M.
The drug was prescribed by a neurologist, a diagnosis of vertebrogenic lumboschialgia, radiculopathy L5, mn hernia L4-5, L5S1, hypesthesia of the outer surface of the right tibia. When taking trental, wild dizziness, before dark in the eyes, although when measuring blood pressure does not fall much (I have a stable 110/70, 38 years). Driving a car is absolutely impossible, so drink the drug only once and for the night.I can not sleep, wake up several times a night, breathe like a fish on ice. Nausea, icy hands, a headache of spasmodic nature, constant tides of blood to the face, I look as if from a bath. Complained about pobochku, the neurologist insists on reception. She did not notice any improvement in her condition in terms of her diagnosis in two weeks. But it's impossible to live with such side effects. In parallel, I drink only milgamma, there has never been a reaction to it. The drug is heavy.
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Svetlana15
Trental 100 is assigned to a son (25 years) by a rheumatologist 2 times a day for one tablet. Do not exclude SCR (in immunoblot antibodies to double-stranded DNA - positively), vasculitis is present. Asthma, a pathological reaction to many medications (Quincke's edema, is removed by dexazone in a vein), including prednisolone. At the moment, there is a change in the color of the legs and hands when the position changes (from normal to purple or dark gray), numbness of the hands and feet repeatedly over the day, hemorrhagic rash on the body appears even from the cuff when the pressure is measured or from the tourniquet when take blood from the vein.Will not these pills exacerbate the permeability of the vascular wall, which is now so great? Or improving blood circulation, on the contrary will reduce permeability?
Administrators
admin
Svetlana15, To say one description of the problem is difficult, it is necessary to look. Circulatory disturbances are most likely to be described, so that Trental's treatment can be considered justified. In such complex cases it is better to try to collect the full-time opinions of several doctors and address this problem to another rheumatologist, for control and adequacy of the appointment.
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Anna T
Hello. Prompt, please, has read through in contra-indications for application trentala there are extensive bleedings in a retina of an eye. At me because of a diabetes (18 years already) there was this diagnosis and treatment by laser therapy, 8 operations for now is spent. The treatment is not over yet, there are two laser surgeries ahead. Now sent to the day hospital for supportive treatment as a diabetic, feet are numb. The attending physician of the hospital appointed trental in droppers.The endocrinologist recommended (and the podiatrist too) a course espalipon (droppers) + tioktatsid in tablets three months. The doctor at the hospital said that this would not have the effect that the trental is better, and in general the espalipon is not available, I offered to pay it, to which the doctor replied that it is prohibited. On the question of whether it is possible to take trental in my eye disease, she said that it is possible. Tell me, can you really take it to me, as were extensive hemorrhage, the treatment lasts for several months and is not yet complete, as there is still a strong edema following retinal hemorrhages, which could not yet lift in operations and injections. Thank you in advance for your reply.
Administrators
admin
Anna TIn your case, Trental is a contraindication for use. Show your doctor the instructions for the drug.
Guests
Irina
I have SLE and Raynaud's syndrome. I drip Trental every six months. One ampoule per 250 saline, slowly, not less than an hour. If it's faster, then it starts to shake me, like with chills. Very positive effect of droppers and pain in the legs pass, and the head becomes clearer, and in the fingers is better sensitivity, sleep is normalized.And from the pills there is absolutely no curative effect, only insomnia.
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Julia 79
Good afternoon. I take trental 100 3 times a day. Approximately in 2-3 weeks feet began to hurt or be ill; be sick round the clock. Is this a side effect? Do I need to stop taking the drug?
Administrators
admin
Julia 79It is more likely that the vessels on the legs are clogged, and Trental began his positive action to improve the vascular blood flow of the lower extremities, hence the pain. The main thing is that there are no blood clots in the vessels. It is better to address this issue to the treating doctor, but the disease, for the treatment of which Trental is appointed, is not described in the question.
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Ashatan
Good afternoon. Diagnosed: right-sided primary coxarthrosis of the 3rd degree, ANGBC, bilateral gonarthrosis of 2 tbsp. Recorded for May for consultation and solution of the issue of prosthetics. Until then, the orthopedist recommended the following treatment:
1. Trentalum in tablets 1t * 2 times a day for 2 months 2 courses per year
2. Reception of chondroprotectors (arthra, alflutop, teraflex) 2 courses per year
Alflutop already began to stab under the prescription of the neurologist (the hernia L4-5 has been removed - operation was 16.01.18). Unfortunately, already at home I saw that the dosage of trental is not indicated. To the neurologist I will get in 10 days - I would not like to waste time.
Question: Is it possible to combine injections of alflutope and trental tablets, what dose of trental to take?
I have a uterine myoma 20 mm, a hemangioma in the vertebra. Thank you very much in advance.
With respect, Natalia
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Nesty2018
Good afternoon. She turned to the therapist, on the weak vessels, which recently began to burst on the lower and upper eyelids, after practicing yoga in upturned poses. There are bruises, before there was such a little bit just a little bit. The last time is horror ... all the eyelids are bruised. The doctor appointed venarus, as well as trental or pentoxifylline. I read the annotations to these two drugs and I think, are not they very strong in my case? The diagnosis so far no no, said it must be observed, drink tablets and come in a month. So many side effects I'm afraid to start drinking. What do you advise?
Administrators
admin
Ashatan, Trental dosage should be consulted by doctors or see the medication regimen (100 mg 3 times a day to start). Without knowledge of the medical history and the profile of the disease, it will be difficult to suggest something. With Alflutop Trental combined, but with other chondroprotectors (Arthra, Teraflex), I would not take it (increases the risk of bleeding).

Given fibroids, I would draw attention to the additional risk of bleeding. Begin treatment Trental cautiously and watch your health (the appearance of bleeding, the color of the skin).
Administrators
admin
Nesty2018, I would start with something simpler, for example, with Ascorutin. If this is a normal hemorrhage, having a weakness of the vascular wall, then such a drug should help. Perceive, look for the dynamics of your bruises, and then you will see. If it does not help, then check for coagulability, biochemical tests and start taking drugs more seriously. I understand from the question the age is still young and it's too early to start with serious medications.Perhaps the physical load is prohibitive or not for your body the stated set of exercises, go to a vertical, and not an upside down position.
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larisakorolek
What can replace trental in erythremia? Her husband has been taking him for 10 years. There were big problems with the stomach. We tried to take a break in taking trental, but hemoglobin increased to 200 g / l.
Administrators
admin
larisakorolekTo prevent thrombosis and embolism in the case of erythremia, a safer means than Trental can not find. What can I use more: acetylsalicylic acid, clopidogrel, but in the case of gastrointestinal problems this choice is worse than Trental. You can try to replace Trental with Pentoxifylline (the active substance is the same, but it can go better). Or use dipyridamole, heparin. In general, try with your doctor to find the best combination, although it is not easy.
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aviator
Hello.My father is 93 years old, he is a WWII veteran. In August of last year, began to complain of aching pain in the heel of the right leg, which manifested itself in the daytime and at night did not allow to sleep. A small ulcer formed on the outside of the heel, which was not healed at all. The surgeon, having examined his father, said that microcirculation of blood in the lower limbs was disturbed. There were prescribed antibiotics and tranthal drippers 8 pcs., At discharge the surgeon said that it is necessary to drink pills trental 400 for 1 pc. in a day. The pain has passed, the ulcer has healed. Six months passed, I came to the polyclinic to find out if I could take a break in taking trental for a while. There were three surgeons in the ordinarian's office, and their opinions were divided. One says that the trental intake should be continued all the time, the other one - that you can interrupt for a couple of months, the third one says that you can stop taking it until the appearance of ischemic pains again. Sugar and cholesterol in the blood are normal. I do not know what to do. Please help with advice.
Administrators
admin
aviatorWhat is your motivation for canceling Trental - worsening of father's health, economic reasons or own desire? If the last reason, it is better not to cancel, in 93 years you can live to a logical outcome on Trental, there will be nothing terrible,if the drug is tolerated by the patient well. If the lack of funds or the deterioration of health as a result of taking Trental, then you can cancel. Ischemic pain does not know how you will understand at this age, that it is them, but in the words of the last surgeon from the consultation there is more truth.
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grigor
The dear doctor! Is it possible to do trental injections intramuscularly? In the pharmacy they said that the trental is introduced only in \ in. My wife and I learned how to inject each other in / m, and if I do it, I need to go to the hospital or pay money to private traders. On the Internet they say, and even here in the comments, what you can do and in / m, but at the same time, you need to inject the medicine deeply and slowly. And how deep? You can only do with the needles of a syringe. And yet - is there an equivalent replacement of trental for pentoxifylline, the difference in their price is several-fold. I've been taking a cardiomagnet for several years, should I cancel it with pentoxifylline, because it also dilutes the blood? Sincerely. Waiting for an answer.
Administrators
admin
grigor, Drug forms of intramuscular injections of Trental in the territory of Russia are not registered. Medication must be administered correctly. Therefore, intramuscularly it is under their own responsibility, we do a lot of things not as prescribed, and then complain about side effects and complications. Can not enter intravenously - drink in tablets, this form of Trental exists.

Trental in composition is the expensive branded pentoxifylline. If there is a question to be treated with Pentoxifylline or not treated at all, you can replace it with a 100% analogue. There is money to be treated with branded medicines, treated branded.
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grigor
Thank you so much! Your information is very useful for me.
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meb
Good afternoon. My age is 71 years old, in 2009, I was diagnosed, varicose Article 2, in 2011, heart surgery, bypass surgery 1MKSH 5, 25 May 18, NK Atherosclerosis of the arteries occlusion of PCA from both sides. UZD of arteries and veins NK: signs of diffuse polysegmentary atherosclerosis of arteries NK. Stenosis of the iliac femoral arteries. Occlusion of popliteal arteries.The blood flow velocity at the stop level is 25-30 cm per second. Echographic signs of varicose N.K. Recommended: 1. Trental 10.0 vn.Venno No. 10. 2. Solcoseryl vn.Venno number 10. 3. Vazonite 1t-2 a day. Vazonitis I take 8 days, from tomorrow I take drip trental 200 mg. The question, trental to take, now one tablet 600 mg, a day? After the dropper, trentala in the same hand, drip solkoseril? Should I wear golf shoes with occlusion? Regards, Valentin.
Administrators
admin
mebPro Trental did not understand. That is, now take in tablets, and then add another and intravenously? So no one does and the drug is taken either in tablets or intravenously and prescribe sufficient therapeutic dosages of the drug in one dosage form. At least the attending physician had to talk to you about this moment. If you do not mix Trental and Solcoseryl in one bottle, it is permissible to drip into one vein. Knee-high socks.
Administrators
admin
Feedback from the site visitor Love moved to the required section:
I took the trental in the form of droppers 3 times, the reaction after - strong flushes, fever, dizziness, which did not pass for several days, the state is disgusting ... I did not do 2 prescribed droppers, although I used to take it with improvements (after ischemic stroke).
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OLG
Tell me please. Whether because of reception of tablets trental 400 the reddened scrotum and an entrance aperture mocheispuskatelnogo the channel can blush? Tablets I take 5 days.
Administrators
admin
OLG, Redness due to increased blood flow and microcirculation is possible, but it is necessary to look to see if these changes are caused by other causes (infections, allergic reactions and other possible causes).
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pelagia
I am 65, diagnosed with intermittent claudication. In 2012, there was no heart attack, two years ago, two stents were placed in the vessels of the heart, and a year ago, an operation was performed to clean the carotid arteries (left). I'm a hypertensive patient, but now the pressure is 126-130 / 76-78, the Crimson, according to the descriptions, is approaching the 3 stages, sent to tranthal drippers. There is IHD, angina.I remember the words of the cardiologist in the hospital that they say that this trental is written, and then they get to me with heart attacks (then the neurologist prescribed the pills), I did not drink them. I can not understand I can trental? I did not tolerate brilith very badly, but I drank a year. Advise.
Administrators
admin
pelagia, The choice? Live with limp and ghostly certainty that there will not be a heart attack. With that earlier it already happened, even without Trental. Available on the description of angina also adds risk when taking Trental, but we must understand that to live to retirement age and not have any sores is simply impossible. Treatment of age patients, almost always, is the choice of the best of the worst. Here the question is in choosing a trustworthy doctor and adopting his therapy scheme to be as healthy as possible.
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Natalia 08042015
Hello. The doctor-neurologist has appointed or nominated to the daddy including trental intravenously. Diagnosis of polyneuropathy against a background of vitamin B12 deficiency. Tell me, please, if the trental can be admitted with the concomitant diagnosis of cholelithiasis,can there be an exacerbation? What then is it permissible to replace trental? (The question is not for self-treatment). And can trental intravenously strengthen angina pectoris, which is also there?
They told us that many droppers with trental were causing headache and dizziness. How often does it occur and is it associated with a strong lowering of blood pressure from the trental? The papal angina and stenosis, last year there was a pre-infarction condition.
In the recommendations of the doctor it is written "trental slowly." Is it because trental at the introduction of painful? It is very necessary to know, and then drip will be in local conditions (in the CRH), not in the city.
Thank you very much in advance for your reply.
Administrators
admin
Natalia 08042015, Considering concomitant stenosis (I so understood in a question of Pentoxifylline the same patient appears) intravenous introduction of analogue, including Trentala is not admissible, in view of the indicated contraindications. I would generally leave the group of angioprotective-vasodilators and stopped on the previously recommended vitamins of group B and Berlition or Tyoktatsida (if I do not confuse anything).Yes, it would be good to give a vascular in this situation, but contraindicated drugs can be used when it is already quite edge and better in the hospital (although you will stab in the CRH and there can be the proper help, but the risk remains).
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Natalia 08042015
Thank you very much for your help and moral support! As a heavy load from the shoulders ... Health to you, admin, and good luck in business for your invaluable work here!
In your opinion, which of the vascular analogues in the group of actions is theoretically applicable in our case instead of trental? The question is in the background, not for self-treatment. We will try to solve the problem correctly in real life.
Administrators
admin
Natalia 08042015, I already wrote that according to your description of the problem Trental or other drugs based on pentoxifylline the patient will not get anything. Perhaps this is my personal judgment on the description, without a real examination and analysis results, angiography, but it seems that Trental in your case is an unjustified risk, and the benefits of using it are not obvious.

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