Normaz - instructions for use, analogs, testimonials and release forms (syrup) of a medicinal laxative for the treatment of constipation and dysbiosis in adults, children (including infants and newborns) and during pregnancy. Composition
In this article, you can read the instructions for using the drug Norma. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Norma in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Norma if there are existing structural analogues.Use to treat constipation and dysbiosis in adults, children (including infants and newborns), as well as during pregnancy and lactation. Composition of the preparation.
Norma - laxative. Has a hyperosmotic, hypoammonemic, laxative effect, stimulates intestinal peristalsis, improves the absorption of phosphates and calcium salts.
Under the influence of the drug there is a change in the flora of the colon (an increase in the number of lactobacilli), which leads to an increase in acidity in the lumen of the colon and stimulates peristalsis. Along with this, the volume increases and the feces softens. As a result, the drug has a laxative effect, without directly affecting the mucosa and smooth muscle of the large intestine. Under the action of the drug, ammonia passes from the blood into the intestine, while the formation of nitrogen-containing toxic substances in its proximal part and, consequently, their absorption into the vena cava system decreases. Action can occur quickly or be delayed - in 24-48 hours.
Has the ability to inhibit the growth of salmonella in the colon. Does not reduce the absorption of Vitamins and is not addictive.
Composition
Lactulose + excipients.
Pharmacokinetics
Absorption is low. It is excreted through the intestine in unchanged form, 3% are excreted by the kidneys.
Indications
- chronic constipation;
- regulation of stool with hemorrhoids, the need for surgery on the colon and in the anal opening, in the postoperative period;
- hepatic precoma and coma;
- hepatic encephalopathy;
- hyperammonemia;
- dysbiosis;
- salmonellosis (with the exception of generalized forms).
Forms of release
Syrup.
There are no other dosage forms, be it pills or suspensions.
Instructions for use and dosage
The drug should be taken orally after a meal.
For constipation, adults in the first 3 days are prescribed 15-40 ml per day, then 10-25 ml per day. Children older than 6 years - in the first 3 days prescribe 15 ml per day, then - 10 ml per day, at the age of 1-6 years - 5-10 ml per day, at the age of 1 year - 5 ml per day. Duration of treatment from 4 weeks to 3-4 months.
With hepatic coma, precoma, encephalopathy and hyperammonemia, the initial dose is 30-60 ml 3 times a day. Then the dose is selected so that the soft stool is 2-3 times a day. Treatment can last up to 3 months or more.
In the postoperative period, adults are prescribed 10-30 ml 3 times a day, children older than 1 year - 5-10 ml 2-3 times a day, at the age of 1 year - 5 ml 2-3 times a day. The drug is prescribed after 18-24 h after the operation for 3-5 days.
Side effect
- flatulence;
- nausea;
- diarrhea;
- development of violations of water-electrolyte exchange.
Contraindications
- intolerance to galactose or fructose;
- galactosemia;
- intestinal obstruction;
- rectal bleeding (not hemorrhoidal);
- colostomy, ileostomy;
- suspicion of appendicitis;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
Norma is safe when used during pregnancy and lactation (breastfeeding).
Use in children
Possible use according to the indications and in doses that take into account the age of the patient.
special instructions
With prolonged use of the drug (more than 6 months) should regularly monitor the content of potassium, chlorine and carbon dioxide in the blood plasma.
In gastrocardial syndrome, you should gradually increase the dose to avoid flatulence.
With caution should apply the drug in diabetes mellitus.
Drug Interactions
With the simultaneous use of antibiotics and antacids reduce the effectiveness of lactulose.
Norma changes the pH-dependent release of enteric medicines. It is not recommended to take lactulose within 2 hours after taking other medications.
Analogues of the drug Normase
Structural analogs for the active substance:
- Good luck;
- Dufalac;
- Lactulose;
- The Legend;
- LIVOVOK PB;
- Lizalak;
- Portalac;
- Romfalak.
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