Arthraldol - instructions for use, reviews, analogs and release forms (injections in ampoules for intramuscular injections in solution) for the treatment of arthrosis and osteochondrosis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Arthradol. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Artradol in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Artradol in the presence of existing structural analogues. Use for the treatment of arthrosis and osteochondrosis in adults, children, as well as during pregnancy and lactation.

Arthradol - has chondroprotective properties; inhibits the activity of enzymes that cause degradation of the articular cartilage; stimulates the production of proteoglycans by chondrocytes; strengthens metabolic processes in cartilage and subchondral bone; affects the phosphoric-calcium metabolism in the cartilaginous tissue, stimulates its regeneration, participates in the construction of the basic substance of bone and cartilaginous tissue. It has anti-inflammatory and analgesic properties, helps to reduce the release of inflammatory mediators and pain factors into the synovial fluid through synoviocytes and macrophages of the synovial membrane, suppresses the secretion of leukotriene B4 and prostaglandin E2.

The drug contributes to the restoration of the cartilaginous surfaces of the joints, prevents the collapse of connective tissue; normalizes the production of articular fluid, which leads to better mobility of joints, reducing pain intensity.

Having structural similarity with heparin, it can potentially prevent the formation of fibrin clots in the synovial and subchondral microcirculatory bed.

Composition

Chondroitin sodium sulfate + excipients.

Pharmacokinetics

Artradol is easily absorbed when administered intramuscularly, after 30 minutes it is found in significant concentrations in the blood, after 15 minutes - in synovial fluid. The drug accumulates mainly in the cartilaginous tissue. It is excreted by the kidneys within 24 hours.

Indications

Degenerative and dystrophic diseases of the joints and spine:

• primary arthrosis;
• osteoarthrosis with predominant lesion of large joints;
• intervertebral osteochondrosis.

Forms of release

Lyophilizate for the preparation of solution for intramuscular injection (injections in ampoules for injection).

There are no other dosage forms of this drug, be it pills or ointment.

Instructions for use and designation

Assign intramuscularly to 100 mg every other day. Before use, the contents of the ampoule are dissolved in 1 ml of water for injection. With good tolerability, the dose is increased to 200 mg, starting with the 4th injection.

The course of treatment is 25-35 injections. Repeated course - after 6 months. The duration of repeated courses of treatment is set by the doctor.

Side effect

• allergic reactions;
• hemorrhages at the injection site.

Contraindications

• children's age (effectiveness and safety not established);
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

Caution should be given to the drug during pregnancy and lactation (breastfeeding).

Use in children

The drug is not prescribed for children; efficiency and safety are not established.

special instructions

With the joint use of the drug Arthraldol with indirect anticoagulants, antiplatelet agents, fibrinolytic drugs, more frequent monitoring of the coagulability of blood is required.

With caution should prescribe the drug for bleeding and a tendency to bleeding, thrombophlebitis, as well as during pregnancy and lactation.

Drug Interactions

With simultaneous application with Artradol, the effect of indirect anticoagulants, antiplatelet agents, fibrinolytic agents may be increased.

Analogues of the drug Arthradol

Structural analogs for the active substance:

• Artra Chondroitin;
• Arthrin;
• Kartilag Vitrum;
• Mukosat;
• Structum;
• Hondrogaard;
• Chondroitin;
• Chondroitin sulfate;
• Chondroxide;
• Chondroxide gel;
• Chondroxide ointment;
• Chondrolon;
• Honsurid.

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