Ribomunil - instructions for use, reviews, analogs and formulations (tablets, granules or powder for the preparation of a solution) for the treatment and prophylaxis of sinusitis, pharyngitis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Ribomunil. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Ribomunil in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Ribomunyl analogs in the presence of existing structural analogs.Use for the treatment and prevention of ENT diseases (sinusitis, pharyngitis) in adults, children, as well as during pregnancy and lactation.

Ribomunil - immunomodulator of bacterial origin. Ribomunil is a ribosomal-proteoglycan complex, which includes the most common pathogens of infections of the ENT organs and respiratory tract, and refers to stimulators of specific and nonspecific immunity.

The ribosomes included in the preparation contain antigens identical to the surface antigens of bacteria, and when ingested they cause the formation of specific antibodies to these pathogens (the effect of the vaccine). Membrane proteoglycans stimulate nonspecific immunity, which is manifested in the amplification of phagocytic activity of macrophages and polynucleated leukocytes, increasing factors of nonspecific resistance. The drug stimulates the function of T- and B-lymphocytes, the production of serum and secretory immunoglobulins such as IgA, interleukin-1, as well as alpha and gamma interferons. This explains the preventive effect of Ribomunyl for respiratory viral infections.

The use of Ribomunil in complex therapy allows to increase the efficiency and reduce the duration of treatment, significantly reduce the need for antibiotics, bronchodilators, and increase the period of remission.

Composition

Bacterial ribosomes titrated up to 70% ribonucleic acid (including ribosomes of Klebsiella pneumoniae + ribosomes of Streptococcus pneumoniae + ribosomes of Streptococcus pyogenes + Haemophilus influenzae ribosomes) + Proteoglycans of the membrane part of Klebsiella pneumoniae + auxiliary substances.

Indications

• prevention and treatment of recurrent infections of the ENT organs (otitis, rhinitis, sinusitis, pharyngitis, laryngitis, angina) and respiratory tract (chronic bronchitis, tracheitis, pneumonia, infectious-dependent bronchial asthma) in patients older than 6 months;
• prevention of recurrent infections in patients at risk (often and long-term sick, before the beginning of the autumn-winter season, especially in ecologically unfavorable regions, patients with chronic diseases of ENT organs, chronic bronchitis, bronchial asthma, including children over 6 months and faces old age).

Forms of release

Pills.

Granules for solution for oral administration (sometimes mistakenly referred to as powder).

Instructions for use and reception scheme

Adults and children older than 6 months of the drug prescribed once a day in the morning on an empty stomach.

A single dose (regardless of age) is 3 tablets of 0.25 mg (from 1/3 of a single dose), or 1 tablet of 0.75 mg (with a single dose), or granules from 1 sachet, previously dissolved in boiled water at room temperature.

In the first month of treatment and / or for prophylaxis, Ribomunyl is taken on the first 4 days of each week for 3 weeks every day. In the next 2-5 months - the first 4 days of each month.

To children of early age the drug is recommended to be given in the form of granules.

It is recommended to conduct three-month preventive courses of treatment 2 times a year, six-month preventive courses - once a year.

Side effect

It is observed rarely, does not require drug withdrawal, is characterized by:

• transient hypersalivation at the beginning of treatment;
• nausea, vomiting;
• diarrhea;
• allergic reactions (hives, angioedema).

Contraindications

• autoimmune diseases;
• hypersensitivity to the drug.

Application in pregnancy and lactation

Special studies of the safety and efficacy of Ribomunil during pregnancy and lactation were not conducted.

The use of Ribomunil in pregnancy and lactation (breastfeeding) is possible only after evaluating the intended benefit to the mother and the potential risk to the fetus and the baby.

Use in children

Possible use of the drug in children older than 6 months.

special instructions

Patients should be warned about the possibility of transient elevation of body temperature on day 2-3, which is a manifestation of the therapeutic effect of the drug and does not usually require cessation of treatment. Increased temperature can sometimes be accompanied by minor and transient symptoms of ENT organ infections.

Drug Interactions

Until now, the clinically significant drug interaction of the drug Ribomunil has not been described.

Ribomunil can be combined with other medicines (antibiotics, bronchodilators, anti-inflammatory drugs).

Analogues of the drug Ribomunil

Ribomunil does not have structural analogs for the active substance. The drug is unique in the composition of its constituent components.

Analogues for the pharmacological group (immunomodulators):

• Actinolysate;
• Actipol;
• Aldara;
• Alkimer;
• Anaferon;
• Anaferon child;
• Arbidol;
• Arpetol;
• Arpetolide;
• Arpefly;
• Affinoleukin;
• Bactisporin;
• Beast;
• BronchoWax;
• Bronhomunal;
• Vilozen;
• Wobenzym;
• Galavit;
• Groprinosin;
• Deoxynate;
• Derinat;
• Zadaxin;
• Immunal;
• Immunal plus C;
• Immunomax;
• Immunorm;
• Imudon;
• Imunoriks;
• Imunofan;
• IRS 19;
• Lycopid;
• Marina;
• Myelopid;
• Milife;
• Moliksan;
• Sodium deoxyribonucleate;
• Sodium nucleate;
• Neuroferon;
• ORITOL;
• Polyoxidonium;
• Posterizan;
• Pro Symbioflor;
• Profetal;
• Rhinital;
• Ruzam;
• Splenin;
• Sporobacterin;
• Stemokin;
• Stimforte;
• Superlimph;
• Tactivin;
• Timalin;
• Timogen;
• Timusamine;
• Tonzylgon H;
• Trekrezan;
• Tubosan;
• Uro Vaxom;
• Ferrovir;
• Phlogenzyme;
• Cytovir 3;
• Exalb;
• Epiphamine;
• Erbisol;
• Ergoferon;
• Estifan;
• Echinacea;
• Echinocor.

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