Sorbifer Durules - instructions for use, reviews, analogs and formulations (tablets) of the drug for the treatment of iron deficiency in the body, anemia and increased hemoglobin in adults, children and pregnancy
In this article, you can read the instructions for using the drug Sorbifer Durules. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Sorbifer Durules in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Sorbifer Durules with available structural analogues. Use for the treatment of iron deficiency in the body, anemia and increased hemoglobin levels in adults, children,as well as during pregnancy and lactation.
Sorbifer Durules - anti-anemic drug. Iron - an indispensable component of the body, necessary for the formation of hemoglobin and the flow of oxidative processes in living tissues.
Durules technology provides a phased release of the active ingredient (iron ions) for a long time. Plastic matrix tablets Sorbifer Durules completely inert in the digestive juice, but completely disintegrates under the action of intestinal peristalsis, when the active ingredient is completely released.
Ascorbic acid improves the absorption of iron.
Composition
Iron sulphate + Ascorbic acid (vitamin C) + auxiliary substances.
Pharmacokinetics
Durules is a technology that provides a gradual release of the active substance (iron ions), a uniform intake of the drug. Admission to 100 mg twice a day provides a 30% increase in iron absorption from the drug Sorbifer Durules compared with conventional iron preparations. Absorption and bioavailability of iron - high. Iron is absorbed mainly in the duodenum and the proximal part of the jejunum. Binding to plasma proteins is 90% or more.Deposited in the form of ferritin or hemosiderin in hepatocytes and cells of the phagocytic macrophage system, a small amount - in the form of myoglobin in the muscles.
Indications
- Iron-deficiency anemia;
- iron deficiency;
- prevention of iron deficiency anemia in pregnancy, lactation, in blood donors.
Forms of release
The tablets covered with a cover.
Instructions for use and reception scheme
The drug is taken orally. The tablets covered with a cover, it is impossible to divide or chew. The tablet should be swallowed whole and washed with at least half a glass of liquid.
Adults and adolescents are prescribed 1 tablet 1-2 times a day. If necessary, patients with iron deficiency anemia, the dose can be increased to 3-4 tablets per day in 2 divided doses (morning and evening) for 3-4 months (before replenishing the iron depot in the body).
During pregnancy and lactation for the purpose of prevention, 1 tablet per day is prescribed; for treatment appoint 1 tablet 2 times a day (morning and evening).
Treatment should continue until the optimal level of hemoglobin. For further replenishment of the depot, it may be necessary to continue taking the drug for another 2 months.
Side effect
- nausea, vomiting;
- stomach ache;
- diarrhea;
- constipation;
- ulcerative esophagitis;
- stenosis of the esophagus;
- itching;
- rash;
- headache;
- dizziness;
- skin hyperthermia;
- weakness.
Contraindications
- stenosis of the esophagus and / or other obstructive changes in the digestive tract;
- increased iron content in the body (hemosiderosis, hemochromatosis);
- violation of iron utilization (lead anemia, sideroblastic anemia, hemolytic anemia);
- children under 12 years of age (due to lack of clinical data);
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
It is possible to use the drug Sorbifer Durules during pregnancy and lactation according to the indications.
Use in children
The drug is contraindicated for children and adolescents under 12 years.
special instructions
When applying the drug, darkening of the feces (black feces) is possible, which has no clinical significance.
With caution should apply the drug with peptic ulcer of the stomach and duodenum, inflammatory bowel disease (enteritis, diverticulitis, ulcerative colitis, Crohn's disease).
Drug Interactions
Sorbifer Durules can reduce the absorption of concomitantly used enoxacin, clodronate, grepafloxacin, levodopa, levofloxacin, methyldopa,penicillamine, tetracyclines and thyroid hormones.
Simultaneous use of the drug Sorbifer Durules and antacid preparations containing aluminum hydroxide and magnesium carbonate can reduce iron absorption. Between taking the drug Sorbifer Durules and any of these drugs should be kept as long as possible. The recommended minimum time interval between doses is 2 hours, except for tetracyclines, when the minimum interval should be 3 hours.
Sorbifer Durules should not be combined with the following drugs: ciprofloxacin, doxycycline, Norfloxacin and ofloxacin.
Analogues of the drug Sorbifer Durules
Structural analogs for the active substance:
- Fenules 100;
- Ferroplex.
Analogues for the pharmacological group (drugs for the treatment of iron deficiency):
- Aktiferrin compositum;
- Aloe syrup with iron;
- Biovital elixir;
- Biofer;
- Venofer;
- Vitrum Superstress;
- Vitrum Cirkus;
- Hemofer;
- Gino Tardiferon;
- Likferr 100;
- Maltofer;
- Maltofer Foul;
- Multi Tabs Active;
- Pikovit Complex;
- Special Merz sweets;
- Stress formula with iron;
- Supradin Kids Junior;
- Tardiferon;
- Totem;
- Ferlatum;
- Ferretab;
- Ferrinate;
- Ferro Folgamma;
- Ferrograduum;
- Ferronal;
- Ferronal 35;
- Ferrum Lek;
- Heferol;
- Enfamil Premium 2;
- Enfamil with iron.
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