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Tiberal - instructions for use, reviews, analogs and forms of release (tablets 500 mg) of a medicament for the treatment of giardiasis, amebiasis in adults, children and pregnancy. Composition and interaction with alcohol

Tiberal - instructions for use, reviews, analogs and forms of release (tablets 500 mg) of a medicament for the treatment of giardiasis, amebiasis in adults, children and pregnancy. Composition and interaction with alcohol

In this article, you can read the instructions for using the drug Tiberal. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Tiberal in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tiberal in the presence of existing structural analogs. Use for the treatment of giardiasis, amoebiasis in adults, children, as well as during pregnancy and lactation.Composition and interaction of the drug with alcohol.

 

Tiberal antiprotozoal agent, a derivative of 5-nitroimidazole. It is believed that the mechanism of action is associated with a violation of the structure of DNA of sensitive microorganisms. It is active against Trichomonas vaginalis, Giardia lamblia, Entamoeba histolytica, and also for some anaerobic bacteria (including Bacteroides spp., Clostridium spp., Fusobacterium and anaerobic cocci).

 

The half-life of Ornidazole (the active substance of the drug Tiberal) is greater than that of metronidazole.

 

Composition

 

Ornidazole + auxiliary substances.

 

Pharmacokinetics

 

After ingestion, absorption from the gastrointestinal tract is high. Binding to plasma proteins is 15% or more. Penetrates through the blood-brain barrier (BBB). It is excreted as metabolites by the kidneys (60-70%) and with feces (20-25%), in unchanged form - about 5%.

 

Indications

  • trichomoniasis;
  • amebiasis (intestinal and non-intestinal forms, including amoebic dysentery and amoebic liver abscess);
  • giardiasis;
  • prevention of postoperative complications (especially in operations on the colon or in gynecology).

 

Forms of release

 

The tablets covered with a cover of 500 mg.

 

There are no other forms of the preparation, whether candles, syrup or solution.

 

Instructions for use and reception scheme

 

Inside, after eating.

 

With trichomoniasis: 1 tablet in the morning and evening for 5 days. Children are prescribed, once, 25 mg / kg of body weight per day.

 

With amoebic dysentery: a course of treatment of 3 days, adults and children weighing over 35 kg prescribed 3 tablets, once, in the evening; adults weighing over 60 kg - 2 tablets in the morning and in the evening, children weighing up to 35 kg - 40 mg / kg body weight per day, once.

 

With all forms of amoebiasis: treatment course - 5-10 days, adults and children weighing over 35 kg - 1 tablet in the morning and in the evening, children weighing up to 35 kg - 25 mg / kg body weight once.

 

With giardiasis: adults and children weighing over 35 kg - 3 tablets, once, in the evening, children weighing up to 35 kg - 40 mg / kg, once; course of treatment - 1-2 days.

 

In infections caused by anaerobic bacteria: 500 mg every 12 hours.

 

Side effect

  • nausea;
  • heartburn;
  • dizziness;
  • drowsiness;
  • skin rash;
  • headache;
  • dizziness;
  • impaired consciousness;
  • tremor;
  • stiff muscles;
  • violation of coordination of movements;
  • convulsions;
  • sensory or mixed peripheral neuropathy;
  • nausea, vomiting;
  • diarrhea.

 

Contraindications

  • diseases of the central nervous system;
  • acute neurological diseases;
  • 1 trimester of pregnancy;
  • lactation period;
  • hypersensitivity to ornidazole.

 

Application in pregnancy and lactation

 

Contraindicated in the 1st trimester of pregnancy, during lactation. In pregnancy, use is only possible on absolute indications, if the expected benefit for the mother exceeds the potential risk to the fetus.

 

Use in children

 

The application is possible according to the dosing regimen.

 

special instructions

 

Does not inhibit alcohol dehydrogenase, therefore it is not incompatible with alcohol.

 

Drug Interactions

 

Potentiates the effect of indirect anticoagulants, increases the duration of action of vecuronium bromide.

 

Analogues of the drug Tiberal

 

Structural analogs for the active substance:

  • Avrazor;
  • Gairo;
  • Dazolik;
  • Lornisol;
  • Ornidazole;
  • Ornidazole Vero;
  • Ornion;
  • Ornisid;
  • Ornisid Forte.

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Reviews (4):
Visitors
tigersay
To the child of 8 years.
Could you explain to me why in the treatment of lambia, in addition to the tiberal, they also appointed a makmiror? More precisely - at first appointed makmiror according to instructions, and then immediately - tiberal. I read that only a tiberal, when the course is repeated, cures 99% of lamblias (of course, plus diet and the implementation of recommendations).In this case, the tyber should be taken only once, and the makmirorom "poisoned" a week? Nowhere on the Internet did not read, that when treating here so duplicated anti-infectious drugs.
Thank you in advance.
Administrators
admin
tigersay, In fact lamblia now have become evil and are treated poorly. I in my practice use more Makmiror than Tiberal. As for "weeks mammiror poisoning" here is not your truth, since the active ingredient of the drug Macmorore is low-toxic and even the appointment of doubled doses (what is in the instruction and this is recognized by the manufacturer himself) does not lead to deterioration of the condition, and in some cases even necessary for cure.

With Tiberal worked less (the correct dosage of McMiore usually cured patients from lamblia), but this is my personal opinion as a specialist.

The standard treatment of these two antiparasitic drugs is common (first the McMiore course, then the Tiburan course). So in this combination, too, I do not see anything reprehensible, doctors prescribe such schemes and probably see their effectiveness.
Visitors
aksinia282
Good afternoon! The result of the smear test was with leukocytes 15-20. The gynecologist said that this inflammation and prescribed the following treatment: pills tiberal 5 days, douching with chlorhexidine 2 days, candles Macmyorum complex number 8. By my inattention, I did not specify, it is necessary to do all this simultaneously or in turn after the completion of the previous drug. Tell me, please, how will it be more effective ?! Thanks in advance!
Administrators
admin
aksinia282Judging by the prescribed complex of drugs, you need to take all this at the same time. So the efficiency will be higher than with interruptions.

It is worth noting, in addition, that a swab of inflammation would be good to immediately determine the specific pathogen and flora, which causes inflammation, with the definition of sensitivity to antibiotics. Perhaps, the prescribed complex of treatment will help you the first time, but many people come for a re-treatment and an extensive research is needed. Consider this I described in the future scheme, just in case.Although the mind must immediately identify both the pathogen and drugs for treatment, but it is expensive for our health care and then doctors are hostages of defective medicine.

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