Celestoderm B - instructions for use, analogs, reviews and release forms (cream, ointment or gel 0.1%, with antibiotic garamycin) of a hormonal drug for the treatment of eczema and neurodermatitis in adults, children and pregnancy. Composition

In this article you can get acquainted with the instructions for the use of a hormonal drug Celestoderm B. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Celestoderm B in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Celestoderm B in the presence of existing structural analogues.Use for the treatment of eczema, psoriasis and neurodermatitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Celestoderm B - the effect of the drug is due to the components that make up its composition.

Betamethasone valerate - glucocorticosteroid (GCS) - has anti-inflammatory and antiallergic effect, inhibits the release of cytokines and inflammatory mediators, reduces the metabolism of arachidonic acid, induces the formation of lipocortins, which have anti-edematous activity, reduces vascular permeability.

The microdispersion of this glucocorticosteroid in a low-fat, odorless, leaving no traces on clothes, easily washed off with an ointment or cream base, provides effective penetration into the skin and a rapid onset of action.

Gentamicin is a broad-spectrum antibiotic - when applied topically, it is effective against most common pathogens. Gentamicin susceptible bacteria include sensitive strains of streptococcus (beta-hemolytic, alpha-hemolytic), staphylococcus aureus (coagulase-positive, coagulase-negative and some penicillinase-producing strains), as well as Gram-negative bacteria: Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Proteus vulgaris and Klebsiella pneumoniae.

Composition

Betamethasone (in the form of valerate) + excipients (Celestoderm B).

Betamethasone (in the form of valerate) + Gentamicin (in the form of sulfate) + auxiliary substances (Celestoderm B with garyamicin).

Indications

Local treatment of skin diseases susceptible to glucocorticosteroid (GCS) therapy, in the presence of secondary infection caused by susceptible to gentamicin microorganisms, or when suspected of such infection:

• eczema (atonic, childish, coin-like);
• contact dermatitis;
• seborrheic dermatitis;
• neurodermatitis;
• sunny dermatitis;
• exfoliative dermatitis;
• radiation dermatitis;
• intertrigo;
• psoriasis;
• anogenital and senile itching.

Forms of release

Cream for external use 0.1% (sometimes mistakenly called a gel).

Ointment for external use 0.1%.

Instructions for use and how to use them

Celestoderm B

Outwardly.

Ointment or cream should be applied a thin layer on the affected areas 1-3 times a day, depending on the severity of the condition. In most cases, to achieve the effect, it is sufficient to apply 1-2 times per day.

Celestoderm B with geramycin

Outwardly. Apply a thin layer on the affected skin 2 times a day - in the morning and in the evening.

The frequency of application, other than the recommended, can set the doctor, focusing on the severity of the disease. In mild cases, application once a day is usually sufficient, with more severe lesions, more frequent use may be required.

Side effect

• irritation of the skin (itching, erythema);
• burning sensation, dry skin;
• folliculitis;
• hypertrichosis;
• ugrevidnye rashes (pimples or blackheads);
• hypopigmentation;
• perioral dermatitis;
• allergic contact dermatitis;
• maceration of the skin;
• secondary infection;
• skin atrophy;
• stria;
• prickly heat;
• development of systemic side effects characteristic of glucocorticosteroids (GCS) in large areas of application or long-term treatment: weight gain, osteoporosis, increased blood pressure, edema, ulceration of the mucous membrane of the gastrointestinal tract, exacerbation of hidden foci of infection, hyperglycemia, agitation, insomnia, menstrual cycle ;
• in children - suppression of the hypothalamic-pituitary-adrenal system, Cushing's syndrome, growth retardation, lag in weight gain, increased intracranial pressure.

Contraindications

• hypersensitivity to any of the components of the drug;
• tuberculosis of the skin, skin manifestations of syphilis, chickenpox, herpes simplex, fungal skin diseases;
• the period of vaccination and skin post-vaccination reactions;
• lactation period;
• pregnancy (prolonged treatment of extensive skin areas);
• children's age - up to 6 months.

Application in pregnancy and lactation

Due to the fact that the safety of the use of local glucocorticosteroids (GCS) in pregnant women has not been established, the appointment of drugs of this class during pregnancy is justified only if the benefit to the mother clearly exceeds the possible harm to the fetus. SCS should not be used during pregnancy for a long time or in high doses.

Since it has not been established to date whether SCS can be absorbed into breast milk by topical application and systemic absorption, a decision should be made whether to stop breastfeeding or to abolish the drug, considering how necessary it is for the mother.

Use in children

Celestoderm B can be used to treat children aged 6 months. Children may be more susceptible to the action of local glucocorticosteroids that cause oppression of the hypothalamic-pituitary-adrenal system than older patients.This is due to a higher absorption of the drug in children due to a greater ratio of surface area and body weight.

special instructions

Ointment is used for skin lesions against a background of eczema or psoriasis, and the cream is used for diseases of moist or oily skin.

In the absence of the effect of treatment for 2 weeks, it is recommended that you consult your doctor to clarify the diagnosis and treatment.

If irritation or hypersensitivity occurs during the use of the drug, treatment should be discontinued and the patient should be treated differently.

Any side effects of systemic glucocorticosteroids (SCS), including oppression of the adrenal cortex, can also be noted when using local GCS, especially in children. Systemic absorption of local GCS may increase with prolonged use, treatment of extensive body surfaces or the use of occlusive dressings, especially in children.

Systemic absorption of gentamicin in topical application may increase in case of application to extensive areas of the skin, especially with prolonged treatment or in the presence of skin cracks. In such cases, development of undesirable phenomena characteristic of gentamicin in its systemic application, especially in children, is possible.

With topical application of antibiotics, insensitive microflora, including fungal growth, is occasionally observed. In this case, treatment should be stopped and appropriate therapy prescribed.

Celestoderm B is indicated for external use only and is not intended for use in ophthalmology.

Drug Interactions

The drug for topical application is practically not absorbed into the bloodstream and does not have a systemic effect, in connection with which the interaction with other drugs is minimal.

Analogues of the drug Celestoderm B

Structural analogs for the active substance:

• Acriderm;
• Beloderm;
• Betazon;
• Betamethasone;
• Betamethasone sodium phosphate;
• Betamethasone valerate;
• Betamethasone dipropionate;
• Betliben;
• Betnoveit;
• Diprospan;
• Kuterid;
• Flosteron;
• Celestoderm B with garyamicin;
• Celeston.

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