Iodine - instructions for use, reviews, analogs and formulations (solutions - alcohol 3% and 5%, tablets 80 mg) of the drug for the treatment of injuries, wounds and other infectious and inflammatory skin diseases in adults, children and in pregnancy

In this article, you can read the instructions for using the drug Iodine. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Iodine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of iodine in the presence of existing structural analogues. Use to treat injuries,wounds and other infectious and inflammatory skin diseases in adults, children, as well as during pregnancy and lactation.

Iodine - has pronounced antimicrobial properties. For preparations of elemental iodine, a pronounced local irritant effect on tissues is characteristic, and cauterizing effect in high concentrations. Local action is due to the ability of elementary iodine to precipitate tissue proteins. Preparations that cleave elementary iodine have a much less pronounced irritant effect, and iodides have locally irritating properties only at very high concentrations.

The nature of the resorptive action of preparations of elemental iodine and iodides is the same. The most pronounced effect with resorptive action iodine preparations have on the functions of the thyroid gland. With iodine deficiency, iodides contribute to the restoration of impaired thyroid hormone synthesis. With a normal iodine content in the environment, iodides inhibit the synthesis of thyroid hormones, reduce the sensitivity of the thyroid gland to the TTG of the pituitary gland, and block its secretion by the pituitary gland. The effect of iodine preparations on metabolism is manifested by the intensification of dissimilation processes.With atherosclerosis, they cause a slight decrease in the concentration of cholesterol and beta-lipoproteins in the blood; in addition, increase the fibrinolytic and lipoproteinase activity of blood serum and slow the rate of blood clotting.

Accumulating in syphilitic gums, iodine promotes their softening and resorption. However, the accumulation of iodine in tuberculosis foci leads to an intensification of the inflammatory process in them. Isolation of iodine excretory glands is accompanied by irritation of glandular tissue and increased secretion. This is due to expectorant action and stimulation of lactation (in small doses). However, in large doses of iodine preparations can cause suppression of lactation.

Pharmacokinetics

When exposed to skin or mucous membranes, 30% turns into iodides, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated mainly by the kidneys, intestines, sweat and mammary glands.

Indications

For external use:

• Infectious-inflammatory skin lesions;
• injuries;
• wounds;
• myalgia.

For topical application:

• chronic tonsillitis;
• atrophic rhinitis;
• purulent otitis media;
• trophic and varicose ulcers;
• wounds;
• infected burns;
• fresh thermal and chemical burns of 1-2 degrees.

For oral administration:

• prevention and treatment of atherosclerosis;
• tertiary syphilis.

Forms of release

A solution of alcohol 3% and 5%.

Tablets 80 mg.

Instructions for use

With external use of iodine, the damaged skin is treated.

For oral administration, the dose is set individually, depending on the indications and age of the patient.

Locally used for washing lacunae and supratonsillar spaces - 4-5 procedures at intervals of 2-3 days, for irrigation of the nasopharynx - 2-3 times a week for 2-3 months, for instillation in the ear and rinsing - for 2-4 weeks; In surgical practice and with burns, moistened napkins are applied to the affected surface as needed.

Side effect

• skin irritation;
• iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne);
• skin allergic reactions;
• tachycardia;
• nervousness;
• sleep disorders;
• increased sweating;
• diarrhea (in patients older than 40 years).

Contraindications

Hypersensitivity to iodine. For oral administration - pulmonary tuberculosis, nephritis, nephrosis, adenomas (including thyroid gland), furunculosis, acne, chronic pyoderma, hemorrhagic diathesis, urticaria, pregnancy, children under 5 years.

Application in pregnancy and lactation

Contraindicated for oral administration during pregnancy.

Drug Interactions

Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed). Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity. Weaken the hypothyroid and strugogenic effects of lithium preparations.

Analogues of drug Iodine

Structural analogs for the active substance:

• Iodine fine crystalline instant;
• Potassium iodide;
• Povidone iodine;
• Iodobalance;
• Iodomarin.

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