Elkar - instructions for use, reviews, analogs and forms of release (solution or drops 20%) drugs for the treatment of anorexia and weight loss, correction of metabolic processes in adults, children (including newborns) and pregnancy
In this article, you can read the instructions for using the drug Elkar. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Elkar in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Elkar in the presence of existing structural analogs. Use for the treatment of anorexia and weight loss, correction of metabolic processes in adults, children,as well as during pregnancy and lactation.
Elkar - a drug for the correction of metabolic processes.
L-carnitine (the active substance of the drug Elkar) is a natural substance related to the Vitamins of group B. It participates in metabolic processes as a carrier of fatty acids (including palmitic acid) through the cell membranes from the cytoplasm in the mitochondria, where these acids are exposed to the beta process -oxidation with the formation of ATP and acetyl-CoA.
The drug normalizes protein and fat metabolism, increases the secretion and enzymatic activity of gastric and intestinal juices, improves the absorption of food, reduces excess body weight and reduces the fat content in muscles. Increases resistance to physical stress, inhibits the formation of keto acids and anaerobic glycolysis, reduces the degree of lactic acidosis, contributes to the economical consumption of glycogen and increases its stores in the liver and muscles.
Elkar has an anabolic and lipolytic effect, normalizes the increased basal metabolism in hyperthyroidism, being a partial antagonist of thyroxin.
Pharmacokinetics
After oral administration, it is well absorbed from the digestive tract. Therapeutic concentration is maintained for 9 hours.Well penetrates the liver, myocardium, more slowly - into the muscles. It is excreted by the kidneys, mainly in the form of acyl esters.
Indications
- a syndrome of anorexia nervosa;
- in the recovery period after the diseases and surgical interventions;
- intensive physical activities and sports training (to improve efficiency, endurance and reduce fatigue);
- in the complex therapy of chronic gastritis with a decreased secretory function and chronic pancreatitis with exocrine insufficiency;
- in the complex therapy of skin diseases (psoriasis, seborrhoeic eczema, focal scleroderma, discoid lupus erythematosus);
- mild forms of hyperthyroidism;
- neurologic manifestations in cerebral lesions of vascular, toxic and traumatic genesis;
- diseases accompanied by a deficiency of carnitine (myopathy, cardiomyopathy, mitochondrial diseases with concomitant mitochondrial insufficiency) - to make up for its deficiency in the complex therapy.
In pediatric practice (treatment of children under 3 years under the supervision of a doctor):
- nursing preterm and newborns who have suffered a trauma or asphyxia;
- children with a weakened sucking reflex and low body weight gain, reduced muscle tone, with insufficient development of motor and mental functions, as well as to prevent these disorders in children at risk;
- stunting and lack of weight in children and adolescents under 16 years of age.
Forms of release
Solution (drops) for oral administration 20%.
Solution for injection 100 mg / ml.
Instructions for use and dosage
The drug is taken orally 30 minutes before meals, additionally diluted with liquid.
Adults with a syndrome of anorexia nervosa, as well as during the recovery after a number of diseases and surgical interventions are prescribed 2 g (2 teaspoons) 2 times a day, the duration of use is 1-2 months.
With prolonged physical exertion appoint 1-2 grams (1-2 teaspoons) 2-3 times a day.
To stimulate appetite and increase body weight in patients with chronic gastritis with a decreased secretory function and chronic pancreatitis with exocrine insufficiency, the drug is prescribed in a single dose of 500 mg (1/2 teaspoon) 2 times a day, the duration of use is 1-1.5 months.
In the treatment of skin diseases, a single dose is 1 g (1 teaspoon) 2 times a day, the duration of use is 2-4 weeks.
With growth retardation and hyperthyroidism, the drug is prescribed in a single dose of 250 mg 2-3 times a day. The course of treatment is 20 days. The course of treatment is repeated after 1-2 months break or applied for 3 months without interruption.
With brain lesions of vascular, toxic and traumatic genesis - 0.5-1 g per day for 3-5 days. If necessary, after 12-14 days, appoint a second course.
With primary and secondary Carnitine deficiency, the drug is used in a dose of 50-100 mg / kg body weight with a frequency of 2-3 times a day for 3-4 months.
Children prescribe the drug in the form of an additive to sweet dishes (jelly, compote, juices). Children under the age of 3 years, the dosing regimen is set individually. Children from 3 to 6 years - 100 mg (14 drops) 2-3 times a day, daily dose - 200-300 mg. The course of treatment is 1 month. Children aged 6 to 12 years are prescribed 200-300 mg (1/4 teaspoon) 2-3 times a day, the daily dose is 400-900 mg. The course of treatment is 1 month.
Side effect
- stomach ache;
- phenomena of dyspepsia;
- allergic reactions;
- myasthenia gravis (in patients with uremia).
Contraindications
- individual intolerance.
Application in pregnancy and lactation
The possibility of using the drug during pregnancy is decided individually depending on the clinical situation.
special instructions
For children under 3 years of age, the drug is prescribed under the supervision of a doctor.
Drug Interactions
With the simultaneous use of glucocorticosteroids contribute to the accumulation of carnitine in tissues (except for the liver), anabolic agents enhance the effect of the drug.
Analogues of the drug Elkar
Structural analogs for the active substance:
- Carnithen;
- Carnify.
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