Essley Forte - instructions for use, reviews, analogs and forms of release (capsules or tablets 300 mg) of hepatoprotector for the treatment of hepatitis, cirrhosis, fatty liver, toxicosis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Essley Forte. There are reviews of visitors to the site - consumers of this medication, as well as opinions of physicians specialists on the use of hepatoprotector Essley Forte in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Essential in the presence of existing structural analogues.Use for the treatment of hepatitis, cirrhosis, fatty liver disease, toxicosis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Essley Forte - a product based on essential phospholipids.

Essential phospholipids are the basic elements of the structure of the cell membrane and cellular organelles of the liver. In diseases of the liver, there is always damage to the membranes of the liver cells and their organelles, which leads to disturbances in the activity of the enzymes and receptor systems associated with them, impairment of the functional activity of the hepatic cells, and a decrease in the ability to regenerate.

Phospholipids, which are part of the Essley forte preparation, correspond in their chemical structure to endogenous phospholipids, but exceed the endogenous phospholipids in activity due to their higher content of polyunsaturated (essential) fatty acids. The incorporation of these highly energetic molecules into the damaged sections of the cell membranes of hepatocytes restores the integrity of the hepatic cells, promotes their regeneration. Cis-double bonds of their polyunsaturated fatty acids prevent the parallel arrangement of hydrocarbon chains in phospholipidscell membranes, the density of the phospholipid structure of the cell membranes of hepatocytes decreases, which causes an increase in their fluidity and elasticity, improves the metabolism. The resulting functional blocks increase the activity of enzymes fixed on the membranes and promote the normal, physiological pathway of the most important metabolic processes.

Phospholipids, which are part of the Essley forte preparation, regulate the metabolism of lipoproteins, transferring neutral fats and cholesterol to oxidation sites, mainly by increasing the ability of high-density lipoproteins to bind to cholesterol.

Thus, there is a normalizing effect on the metabolism of lipids and proteins; on the detoxification function of the liver and phospholipid-dependent enzyme systems; which ultimately prevents the formation of connective tissue in the liver and promotes the natural recovery of liver cells.

When phospholipids are excreted in the bile, the lithogenic index decreases and bile stabilizes.

Composition

The lipoid of PPL-400 is 400.0 mg,based on polinenasyschennys phospholipids from soybean lecithin (PPL fraction) with average content of L-alpha-phosphatidylcholine 76% + auxiliaries.

Pharmacokinetics

More than 90% of the ingested phospholipids are absorbed in the small intestine. Most of them are cleaved by phospholipase A to 1-acyl lysophosphatidylcholine, 50% of which is immediately subjected to inverse acetylation in polyunsaturated phosphatidylcholine still during the suction process in the intestinal mucosa. This polyunsaturated phosphatidylcholine with shock lymph enters the bloodstream and from there, mainly associated with high density lipoproteins to the liver form.

Indications

• chronic hepatitis;
• cirrhosis of the liver;
• fatty degeneration of the liver of various etiologies;
• toxic liver damage;
• alcoholic hepatitis;
• violations of liver function in other physical diseases;
• toxicosis of pregnancy;
• prevention of recurrence of gallstones;
• psoriasis (as a means of supportive therapy);
• radiation syndrome.

Forms of release

Capsules 300 mg (sometimes mistakenly called pills).

Instructions for use and reception scheme

Inside.Capsules should be taken whole, washed down with a sufficient amount of water.

For adolescents over 12 years of age and weighing more than 43 kg, as well as for adults, Essyla forte preparation is recommended to take 2 capsules - 3 times daily with meals.

As a rule, the duration of application is not limited.

Side effect

• discomfort in the epigastric region;
• loosening of stool;
• nausea;
• gastralgia;
• rash;
• exanthema;
• hives;
• itching.

Contraindications

• individual intolerance of phosphatidylcholine or other auxiliary components of the drug;
• intolerance to soy;
• children under 12 years of age (lack of sufficient evidence base).

Application in pregnancy and lactation

It is permissible to use Esslyal Forte during pregnancy and lactation as recommended by your doctor.

Use in children

Contraindicated in children under 12 years of age (lack of sufficient evidence base for the use of drugs in this age group of patients).

special instructions

Ophthalmic leave.

Drug Interactions

The drug interaction Essley Forte is not described.

Analogs of Essley Forte

Structural analogs for the active substance:

• Antraliv;
• Brentzialle forte;
• Liventziale;
• Livolife Forte;
• Lipoid PPL 400;
• Lipoid C 100;
• Resalute Pro;
• Phosphontsiale;
• Essentiale N;
• Essentiale forte N;
• Essential phospholipids;
• The Essler.

Analogues for the pharmacological group (hepatoprotectors):

• Ademethionine;
• Alpha lipoic acid;
• Berlition 300;
• Bondjigar;
• Brentzialle forte;
• Gepa Merz;
• Gepabene;
• Heparett;
• Heptor;
• Heptral;
• Covechol;
• Karsil;
• Karsil Forte;
• Laennek;
• Larnamine;
• Legalon;
• Liv 52;
• Liv 52 K;
• Liventziale;
• Livedoksa;
• Lipoic acid;
• Methionine;
• Moliksan;
• Octolipen;
• Ornilatex;
• Ornithine;
• Ornitsetil;
• Progepar;
• Resalute Pro;
• Remaxol;
• Sibektan;
• Silegon;
• Silibinin;
• Silymarin;
• Sylimar;
• Thioctic acid;
• Thiolipone;
• Tiotriazolin;
• Urdoks;
• Ursodeoxycholic acid;
• Ursodez;
• Ursodex;
• Ursuliv;
• Ursor;
• Ursosan;
• Ursofalk;
• Phosphogliv;
• Phosphogliv Forte;
• Phosphontsiale;
• Hepabos;
• Holudexan;
• Exxhol;
• Eslidine;
• Essentiale N;
• Essentiale forte N;
• Essential phospholipids;
• Essencigliv;
• The Essler;
• Essliver forte.

Similar medicines:

Other medicines: