Zakofalk - instructions for use, reviews, analogs and forms of release (tablets 1.36 g) of the drug for the treatment of colitis, Crohn's disease, irritable bowel syndrome in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Zakofalk. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Zakofalka in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Zakofalka in the presence of existing structural analogues. Use for the treatment of colitis, Crohn's disease, irritable bowel syndrome in adults, children, as well as in pregnancy and lactation. Composition of the preparation.

Zakofalk - a remedy that replenishes the deficiency of butyric acid and inulin. Biologically active additive (BAA) to food.

Oily acid is normally produced in the large intestine as a result of the cleavage of normal intestinal microflora of indigestible carbohydrates, which come with food. The main function of butyric acid is the supply of energy to the cells of the colonic mucosa (colonocytes) and maintaining them in a healthy functional state. Oily acid as a product of the vital activity of useful intestinal bacteria is the main regulator of water-electrolyte balance and promotes the absorption of excess water in the colon, preventing liquid stool (diarrhea). It is an energy and regulates substrate for colonocytes, regulates the processes of development and renewal of colonic mucosa cells, strengthens the protective mucosal barrier, reducing visceral sensitivity of the colon to irritating stimuli, especially to its tension in a number of states.

Inulin is a soluble dietary fiber that creates a nutrient medium for the intestinal microflora, thereby stimulating the growth of beneficial bacteria (prebiotic action).As a result of the metabolism of inulin, endogenous butyric acid is formed by the gut bacteria. Inulin is one of the widely used classical prebiotics. Inulin is not digested by human digestive enzymes and easily enters the large intestine, where it stimulates the growth of intestinal bifidobacteria. Due to this, the peristalsis of the colon is improved and the formation of bacterial metabolites useful for the body is taking place. Inulin and metabolites of useful colon microflora have a positive effect on metabolic processes in colon cells and metabolism in general, have an antioxidant effect, which is especially important for the elderly.

Release of active substances in the large intestine. In order to fully realize its basic biological functions, butyric acid when ingestion should fall into the large intestine, not subject to premature absorption in the overlying gastrointestinal tract. This is made possible by the use of a special technology based on a polymeric multimatrix structure that allows tablets to overcome unchanged stomach and small intestine and reach the large intestine.Throughout the colon, a gradual release of active substances occurs. The polymer multimatrix system provides the action of butyric acid and inulin throughout the large intestine for 24 hours.

Composition

Calcium butyrate (butyric acid) + Inulin + auxiliary substances.

Indications

• nonspecific ulcerative colitis (NNC) and other chronic colitis;
• Crohn's disease;
• irritable bowel syndrome;
• functional disorders of the digestive tract (functional dyspepsia, diarrhea);
• as an additional source of butyric acid and inulin.

Forms of release

Tablets 1.36 grams.

Instructions for use and dosing regimen

Inside, before eating, without chewing. Adults - 3-4 tablets a day. Duration of reception not less than 30 days. Depending on the initial level of deficiency of butyric acid and inulin, it is possible to reduce the number of tablets taken to 1-2 per day.

Side effect

• allergic reactions to the components of the drug;
• nausea;
• diarrhea.

Contraindications

• individual intolerance to the components of the product;
• pregnancy;
• lactation.

Application in pregnancy and lactation

Use of the drug Zakofalk contraindicated during pregnancy and lactation (breast-feeding).

Use in children

Not noted.

special instructions

The NMX trimmer does not contain lactose, casein and gluten.

Contains a sweetener. When excessive use can have a laxative effect.

Before use, it is recommended to consult a doctor.

Drug Interactions

Not noted.

Analogues of the drug Zakofalk

Structural analogues for the active ingredient do not have a drug Zakofalk. The product contains a unique combination of active substances, which has no analogues.

Analogues on the curative effect (agents for the treatment of ulcerative colitis):

• 5-ACA;
• Azathioprine;
• Alginatol;
• Arthrofoon;
• Bifilysis;
• Budenofalk;
• Hydrocortisone;
• Dexamethasone;
• Diprospan;
• Irmalax (dietary fiber with vitamin C and citrus flavor);
• Yogulact;
• Yogulact forte;
• Kalsheyk;
• Colorado;
• Lactobacterin;
• Lemodus;
• Mézavant;
• Mesakol;
• Methyluracil;
• Metizred;
• Mukofalk;
• Neonatrix;
• Pentasa;
• Prednisolone;
• Probiophore;
• Rheopolyglucin with glucose;
• Salosinol;
• Salofalk;
• Sulfasalazine;
• Triamcinolone;
• Urbazon;
• Fortecortin;
• Phthalazole;
• Celeston;
• Eglonyl;
• Enterosan.

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