Maxitrol - instructions for use, reviews, analogs and forms of release (eye drops) drugs for the treatment of conjunctivitis, blepharitis, iridocyclitis and other eye diseases in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Maxitrol. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of physicians specialists on the use of Maxitrol in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Maxitrol in the presence of existing structural analogues. Use for the treatment of conjunctivitis, blepharitis, iridocyclitis and other eye diseases in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Maxitrol - a combined preparation for topical application in ophthalmology.

Neomycin has a bactericidal effect, disrupting the synthesis of the bacterial cell protein. It is active against Staphylococcus aureus (Staphylococcus aureus), Corynebacterium diphteriae, Streptococcus viridans (streptococcus), Escherichia coli (E. coli), Klebsiella pneumoniae (Klebsiella), Proteus vulgaris (Proteus), Aerobacter aerogenes, Haemophillus influenzae.

The mechanism of action of polymyxin B is mainly due to blockade of the permeability of the cytoplasmic membrane of bacterial cells. It is active against Pseudomonas aeruginosa, Aerobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Koch-Weeks bacillus.

Dexamethasone is a glucocorticosteroid (GCS), a hormone. Has anti-inflammatory, antiallergic and desensitizing effects. Has an antiexudative effect. Dexamethasone effectively suppresses inflammatory processes.

Combination of SCS with antibiotics allows to reduce the risk of development of the infectious process.

Composition

Dexamethasone + Neomycin + Polymyxin B sulfate + excipients.

Pharmacokinetics

With topical application, systemic absorption is low.

Indications

Infections of the eyes and its appendages:

• blepharitis;
• conjunctivitis;
• keratoconjunctivitis;
• keratitis;
• iridocyclitis.

Prevention of postoperative infectious complications.

Forms of release

Eye drops.

Other dosage forms, be it ointment or drops in the nose, do not exist.

Instructions for use and how to use them

Locally. With a mild infectious process, 1-2 drops in the conjunctival sac 4-6 times a day at intervals of 1-2 hours - during the day and at intervals of 2 hours - during the night.

In acute severe infectious process, 1-2 drops in the conjunctival sac every 60 minutes with a decrease in the frequency of instillations of the drug as the phenomena of inflammation decrease.

Duration of treatment - from 1 day to several weeks.

Side effect

• an allergic reaction, accompanied by pruritus and lump of the eyelids, hyperemia of the conjunctiva;
• increased intraocular pressure with possible subsequent development of glaucoma, optic nerve damage and visual fields (with the use of the drug for more than 10 days, monitoring of intraocular pressure is necessary);
• posterior subcapsular cataract;
• slowing down the process of wound healing;
• topical application of steroids in diseases that cause thinning of the cornea or sclera can lead to their perforation;
• the development of secondary infection is observed after the use of combined preparations containing SCS in combination with antibiotics;
• with prolonged use of steroids, the development of fungal infections of the cornea is possible.

Contraindications

• individual hypersensitivity to the components of the drug;
• viral diseases of the eyes (including keratitis caused by Herpessimplex (herpes), chicken pox);
• mycobacterial infection of the eyes;
• tuberculosis diseases of the eyes;
• acute shingles;
• fungal diseases of the eyes;
• condition after removal of the foreign body of the cornea;
• a purulent infection of the mucous membrane of the eye and eyelids caused by microorganisms resistant to the action of neomycin, a purulent corneal ulcer.

Application in pregnancy and lactation

Sufficient experience in the use of the drug Maxitrol during pregnancy and lactation is not present. It is possible to use the treatment for pregnant women on prescription of the attending physician if the expected curative effect exceeds the risk of development of possible side effects. It is necessary to interrupt the use of the drug for the period of breastfeeding.

Use in children

Safety and effectiveness of the drug for children are not established.

special instructions

The bottle must be closed after each use. Shake the bottle before use.

The appearance of non-healing ulcers on the cornea after prolonged treatment with steroid preparations may indicate the development of fungal infestation. Secondary bacterial infection may occur as a consequence of suppression of the protective reaction of the patient's body.

Cautiously appoint Maxitrol for glaucoma, cataract.

Drug Interactions

Interaction with other drugs is not currently known.

In case of use with other local ophthalmic preparations, the interval between their use should be at least 10-15 minutes.

Analogues of the drug Maxitrol

Structural analogs for the active substance:

• Polidex.

Analogues on the curative effect (remedies for the treatment of conjunctivitis):

• Arthromax;
• Berberil N;
• Bronal;
• Vitabakt;
• Garamycin;
• Gentamicin;
• Hydrocortisone;
• Histalong;
• Grunamycin syrup;
• Dexamethasone;
• Zanotsin;
• Zindolin;
• Ilozon;
• Innolier;
• Colbiocin;
• Levomycetin;
• Liprokhin;
• Maxidex;
• Midrim;
• Naklof;
• Okatsin;
• Okostistin;
• Okulokhel;
• Ofloxacin;
• Plivasept;
• Poludan;
• Prenatsid;
• Sofradex;
• Sulfacil sodium;
• Tebridex;
• Tobrex;
• Totatsef;
• Uniflox;
• Floxal;
• Furagin;
• Furacilin;
• Fucitalmic;
• Cefetrexyl;
• Cephezole;
• Ceftidine;
• Ciloxane;
• Ciprobay;
• Ciprosan;
• Ciprofloxacin;
• Cifloxinal;
• Chibroxin;
• Hermitsed.

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