Tebridex - instructions for use, analogs, reviews and release forms (eye drops, ointment for eyes) for the treatment of conjunctivitis, blepharitis and keratitis in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Tebridex. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Tebridex in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Teorecdex in the presence of existing structural analogues. Use for the treatment of conjunctivitis, blepharitis and keratitis in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Tebridex - a combined preparation with antibacterial and anti-inflammatory action for topical application in ophthalmology.

Tobramycin is a broad-spectrum antibiotic from the aminoglycoside group. It is active against Gram-positive and Gram-negative microorganisms: Staphylococcus spp. (Including Staphylococcus aureus (Staphylococcus aureus), Staphylococcus epidermidis (including strains resistant to penicillin)), Streptococcus spp. (Strep) (including some beta-hemolytic group A types, some types of non-hemolytic and some strains of Streptococcus pneumoniae), Pseudomonas aeruginosa, Escherichia coli (E. coli), Klebsiella pneumoniae (Klebsiella), Enterobacter aerogenes, Proteus mirabilis, Morganella morganii, Proteus vulgaris (Proteus), Haemophilus influenzae, Haemophilus aegyptius, Moraxella lacunata, Acinetobacter calcoaceticus, and also some strains of Neisseria spp.

Dexamethasone is a glucocorticosteroid (GCS). Has a pronounced anti-inflammatory, antiallergic and desensitizing effect. Has an antiexudative effect.

Composition

Tobramycin + Dexamethasone + excipients.

Pharmacokinetics

With local administration of Teborexa, systemic absorption of dexamethasone is low. About 77-84% of dexamethasone entering the systemic circulation is associated with plasma proteins. With topical application of Teborexa, systemic absorption of tobramycin is low.The concentration of tobramycin in the blood plasma after using 1 drop of Tebridex in each eye 4 for 2 days was below the detection threshold in 9 of 12 patients. It is excreted by the kidneys, mostly unchanged.

Indications

Inflammatory diseases of the eye and its appendages caused by pathogens that are sensitive to the drug:

• blepharitis;
• conjunctivitis;
• keratoconjunctivitis;
• blepharoconjunctivitis;
• keratitis;
• iridocyclitis.

Prevention and treatment of inflammatory phenomena in the postoperative period after cataract extraction.

Forms of release

Eye drops.

Ointment for eyes.

Instructions for use and treatment regimen

Drops

Eye drops are instilled in 1-2 drops in the conjunctival sac of the affected eye (or eyes) every 4-6 hours. In the first 24-48 hours the dose can be increased to 1-2 drops in the conjunctival sac every 2 hours.

Ointment

Locally. A strip of ointment 1.5 cm long is placed in the lower conjunctival sac 3-4 times a day with a decrease in the frequency of application as the phenomena of inflammation decrease. You can combine the use of ointments and drops: ointment - in the evening before going to bed, drops - during the day (with the frequency of use of the drug 3-4 times a day).

Side effect

• itching and swelling of the eyelids;
• redness of the conjunctiva;
• increased intraocular pressure;
• formation of posterior subcapsular cataract;
• slowing down the process of wound healing;
• development of secondary infection (including bacterial), as a result of suppression of the protective reaction of the patient's body;
• the appearance of non-healing ulcers on the cornea after prolonged treatment of SCS may indicate the development of fungal infection.

Contraindications

• viral diseases of the cornea and conjunctiva (including keratitis caused by Herpes simplex (herpes), chicken pox);
• mycobacterial infection of the eyes;
• fungal diseases of the eyes;
• condition after removal of the foreign body of the cornea;
• Children under 18 years of age (for ointment);
• hypersensitivity to any component of the drug.

Application in pregnancy and lactation

There is no sufficient experience in the use of the drug during pregnancy and lactation (breastfeeding).

It is possible to use Tevodex in pregnant women if the expected therapeutic effect exceeds the potential risk of side effects.

Studies in animals have revealed nephrotoxicity and ototoxicity in the fetus when high doses are prescribedtobramycin. Anomalies of fetal development in cases of chronic administration of high doses of dexamethasone have been revealed.

Do not use the drug during breastfeeding.

Use in children

Tebridex ointment is contraindicated in children and adolescents under the age of 18 years.

special instructions

When prescribing Tevodex simultaneously with the antibiotics of the aminoglycoside group for systemic use, the peripheral blood picture should be monitored.

When using the drug Tebridex simultaneously with other eye drops or ointments, the interval between their applications should be at least 5 minutes.

The bottle must be closed after each use. Before use, shake the contents of the vial. When instilling, do not touch the tip of the pipette to the eye.

Drug Interactions

In the case of the simultaneous administration of Tevecdex eye drops with systemic antibiotics from the aminoglycoside group, systemic side effects may be exacerbated.

Analogues of the drug Tevrodex

Structural analogs for the active substance:

• DexaTobrot;
• Tebronzon.

Analogues on the curative effect (remedies for the treatment of conjunctivitis):

• Berberil N;
• Bronal;
• Vitabakt;
• Garamycin;
• Gentamicin;
• Hydrocortisone;
• Histalong;
• Dexamethasone;
• Zanotsin;
• Ilozon;
• Innolier;
• Colbiocin;
• Liprokhin;
• Maxidex;
• Maxitrol;
• Midrim;
• Naklof;
• Okatsin;
• Okulokhel;
• Ofloxacin;
• Plivasept;
• Poludan;
• Prenatsid;
• Riboflavin;
• Sulfacil sodium (albucid);
• Tobrex;
• Totatsef;
• Floxal;
• Furacilin;
• Fucitalmic;
• Cefetrexyl;
• Cephezole;
• Ceftidine;
• Ciloxane;
• Ciprobay;
• Ciprosan;
• Ciprofloxacin;
• Cifloxinal;
• Chibroxin;
• Hermitsed.

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