Nonoxynol - instructions, analogues, reviews
In this article, you can read the instructions for using the drug Nonoxynol. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Nonoxinol in their practice. A big request is to add more actively your comments about the contraceptive: the medicine helped or did not help to get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Nonoxynol in the presence of existing structural analogs. Use for local contraception in women, as well as use in pregnancy and lactation. Contraceptive composition.
Nonoxynol means for contraception. Has a pronounced spermatocidal effect.It causes fragmentation, decreased mobility and death of spermatozoa. It also antimicrobial, antifungal, antiviral and antiparasitic action against a number of pathogens that cause sexually transmitted diseases (the effect is not currently proven).
Nonoxynol 9 leads to damage to the sperm acrosome membrane and to their inability to dissolve the egg cell membrane when it is inserted into the vagina as part of spermicidal ointments, suppositories, beads, and the like. It is a part of spermicidal lubricants of most condoms, uterine (cervical) caps, sponges and diaphragms. A 2004 study showed that during the use of vaginal contraceptives (films, candles and gels) with nonoxynol-9 as an active ingredient for more than six months, their effectiveness was 80 to 90%.
It is also widely believed that some of the protective effects of sexually transmitted diseases (and even HIV), of pelvic inflammation and infertility are inherent in nonoxynol 9, but in October 2001, WHO issued a report stating that nonoxynol-9 does not protect against sexually transmitted diseases by way of (in particular, gonorrhea, trichomoniasis, bacterial vaginosis, chlamydia and candidiasis) and HIV.Moreover, its use in one of the studies led to an increase in susceptibility to human papillomavirus.
Composition
Nonoxynol + auxiliary substances.
Indications
Applied as a contraceptive for:
- irregular menstruation;
- the need for occasional protection from pregnancy, in particular with an irregular sexual life;
- simultaneous use of drugs that reduce the effectiveness of oral hormonal contraceptives;
- the need for termination for a short or long period of oral hormonal contraceptive use;
- the presence of contraindications to the use of intrauterine contraception or oral hormonal contraceptives.
Forms of release
Vaginal Candles 120 mg.
Other dosage forms, be it tablets or capsules, at the time of publication of the drug in the Directory did not exist.
Instructions for use and how to use them
Intended for intravaginal application. It should be inserted deep into the vagina 10 minutes before sexual intercourse.
At each sexual intercourse it is necessary to use new candles.
Side effect
- individual reaction to the drug in the form of irritation of the vaginal mucosa (burning, itching).
Contraindications
- colpitis;
- erosion of the cervix;
- vaginitis;
- salpingo-oophoritis;
- anatomical features that make it difficult to use candles;
- hypersensitivity to the active ingredient of the drug.
Application in pregnancy and lactation
In pregnancy and lactation (breast-feeding), Nonoxynol is not used.
Use in children
It is not used until the onset of menarche.
special instructions
For at least six hours after the end of sexual intercourse, do not use the toilet of the vagina, as this may result in a weakening of the contraceptive effect.
Simultaneous use of candles with a condom is possible.
It is not a means of emergency contraception and can not be used after a sexual intercourse.
When itching in the vagina should abandon the use of candles Nonoxinol. With regular use of suppositories, the likelihood of side effects increases.
When melting the suppository because of accidental overheating, it can be reused after solidification in the refrigerator.
Drug Interactions
Because of the possible reduction in spermicidal activity, nonoxynol suppositories should not be used with other drugs intended for intravaginal administration.
Analogues of the drug Nonoxynol
Structural analogs for the active substance:
- Patent Oval H;
- Sterilin.
Analogues for the pharmacological group (contraceptives for local contraception):
- Benatex;
- Benzalkonium chloride;
- Gynecotheque;
- Contract;
- Contraceptin T;
- Patent Oval H;
- Spermatex;
- Sterilin;
- Pharmaginex;
- Pharmatex;
- Erotex.