Erinit - instructions, analogues, reviews
In this article, you can read the instructions for using the drug Erinith. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Erynit in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Erinite in the presence of existing structural analogs. Use for the treatment of IHD, angina and the prevention of seizures, heart failure in adults, children, as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.
Erinith - a peripheral vasodilator with a predominant effect on venous vessels, an antianginal agent. The action is associated with a decrease in preload (the expansion of peripheral veins and a decrease in the flow of blood to the right atrium) and postnagruzki (reduction in OPSS), as well as with a direct coronary expansive effect. Promotes redistribution of coronary blood flow in the area with reduced blood supply. In patients with IHD, angina increases exercise tolerance. With heart failure helps discharge the myocardium by reducing preload. Reduces pressure in a small circle of blood circulation. In comparison with nitroglycerin, the effect develops more slowly, but is characterized by a longer duration.
Composition
Pentaerythrityl tetranitrate + auxiliary substances.
Pharmacokinetics
When administered pentaerythritol tetranitrate is slowly absorbed from the digestive tract.
Indications
- IHD, angina pectoris (prevention of attacks, including in the post-infarction period);
- heart failure (as part of complex therapy).
Forms of release
Tablets 10 mg.
Instructions for use and dosing regimen
Inside (1 hour before meals) 10-20 mg (1-2 tablets) 3-4 times a day, if necessary - up to 40 mg 4 times a day, it is permissible to appoint 80 mg twice a day.
To prevent night attacks, angina pectoris is prescribed 20 mg at bedtime. The course of treatment usually lasts 2-4 weeks. Repeated courses - as directed by a doctor.
Side effect
- dyspeptic symptoms (nausea, vomiting, diarrhea);
- feeling tired;
- anxiety;
- headache;
- dizziness;
- orthostatic hypotension;
- increased sweating;
- skin allergic reactions.
Contraindications
- acute or recently transferred myocardial infarction;
- severe arterial hypotension;
- increased intracranial and intraocular pressure;
- hypersensitivity to pentaerythritol tetranitrate.
Application in pregnancy and lactation
During pregnancy and lactation, apply Erynit with caution.
Application in elderly patients
Use with caution in the elderly.
Use in children
In children, the drug is not used.
special instructions
Due to the slow development of the effect, Erinit is not used for cupping angina attacks.
With caution apply for violations of cerebral circulation (especially with hemorrhagic stroke), with a tendency to arterial hypotension, in the elderly.
With prolonged use, a decrease in the therapeutic effect (due to the development of tolerance) is possible. When using the drug once a day in combination with other antianginal drugs, the risk of developing tolerance is less.
During the period of treatment, drinking is contraindicated.
Drug Interactions
If you are taking other medicines at the same time, you should consult your doctor.
Under the influence of dihydroergotamine, there may be a decrease in the antianginal effect of Erinitis. The combination of these drugs is considered to be irrational.
The combination with Propranolol is rational, because antianginal effect of the drug is enhanced.
Ethanol enhances the action of Erinith.
Analogues of the drug Erinit
There are no structural analogs to the active substance of the drug Erinit.
Analogues for the pharmacological group (nitrates and nitrate-like agents):
- Amyl nitrite;
- Aerosonite;
- Gluconite;
- Dilaside;
- Dinisorb;
- Isacardin;
- From MacArthard;
- Is Mac Spray;
- Isoket;
- Isolong;
- Isonate;
- Isosorbide dinitrate;
- Isosorbide mononitrate;
- Cardiac;
- Cardix;
- Carneland;
- Corvaton;
- Molsidomine;
- Monizide;
- Monizol;
- Mono Mack;
- Mono Mack Depot;
- Mono Rum retard;
- Monolong;
- Monosan;
- Monochinkwe;
- Monochinkwe retard;
- Nitradisk;
- Nitro;
- Nitroglycerine;
- Nitrodzhekt;
- Nitrocore;
- Nitrolong;
- Nitromint;
- Nitrogen;
- Nitroung forte;
- Nitrosorbide;
- Nitrospray;
- Nitrosprint;
- Olicard;
- Pectrol;
- Pentacard;
- Perlingant;
- Sidnofarm;
- Sustak mite;
- Sustak forte;
- Sustonite;
- Trinitrolong;
- Efoks;
- Efoks long.