Corilip - instructions, reviews, analogs
In this article, you can read the instructions for using the drug Corilip. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Corilip in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Korilip in the presence of existing structural analogues. Use for the treatment of immunodeficiency, infections, malnutrition or hypotrophy in adults, children (including infants and newborns), as well as during pregnancy and lactation. Composition of the preparation.
Corilip - a combined drug, the effect of which is determined by the effects of its Vitamins and coenzymes, as well as their synergistic effect.
Cocarboxylase (coenzyme) catalyzes the carboxylation and decarbobic-suction of alpha-keto acids, participates in the processes of carbohydrate metabolism. Through participation in the pentose cycle, indirectly regulates the synthesis of nucleic acids, proteins, lipids. Promotes correction of metabolic acidosis and cellular hypoxia, as well as other metabolic disorders (insufficiency of the liver, kidneys, cardiovascular system, chronic intoxication).
Riboflavin (vitamin B2) as a coenzyme of flavinoproteins participates in the regulation of oxidation-reduction reactions (in the processes of carbohydrate, protein and fat metabolism). It plays an important role in the synthesis of hemoglobin and in maintaining the normal visual function of the eye, the condition of the mucous membranes and skin.
Thioctic acid is involved in the oxidative decarboxylation of pyruvic acid and other alpha-keto acids, in the regulation of lipid and carbohydrate metabolism, plays an important role in the process of energy production in the body.Thioctic acid has a hepatoprotective effect, improves the detoxification function of the liver, protects against the effects of exo- and endotoxins.
Coripil improves tissue metabolism under various physiological and pathological conditions, requiring correction by cofactors and substrates.
Composition
Kokarboksilazy hydrochloride + Riboflavin + Thioktova (alpha-lipoic) acid + auxiliary substances.
Pharmacokinetics
Data on the pharmacokinetics of the drug Corilip are not available.
Indications
As a monotherapy or as an addition to basic therapy for various pathological conditions in children, including:
- chronic tissue hypoxia;
- decreased immunity;
- bacterial and viral infections;
- chronic somatic diseases;
- chronic intoxication;
- condition after severe illness;
- malnutrition (hypotrophy).
Periods of intensive growth and development of new functions in the child, with intense physical and mental stress, in stressful situations.
As a general restorative for prevention during the epidemic of infectious diseases.
Forms of release
Candles rectal (Corilip and Corilip Neo for infants and newborns).
Other dosage forms, be it drops, tablets or capsules, do not exist.
Instructions for use and how to use them
Candles of Corilip
The drug is used rectally. Having released from packing, it is necessary to enter a candle in an anus (after preliminary emptying of an intestine).
Newborns and infants are prescribed 1/2 suppository per day; children (aged 1 year to 6 years) - 1 suppository per day; children aged 6 to 14 years - 1-2 suppositories per day.
The duration of the course of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 months).
Candles of Corilip Neo
The drug is used rectally. Having released from packing, to enter a candle in an anus after preliminary emptying of an intestine.
Suppositories prescribe to children up to 1 year of 1 suppository per day.
The duration of the course of treatment is 10 days. The total duration of treatment is 3-4 courses with an interval of 20 days (3-4 months).
Side effect
- hives;
- itching;
- bronchospasm;
- dyspepsia.
If adverse reactions occur, the patient should stop taking the drug and consult a doctor.
Contraindications
- proctitis;
- rectal bleeding;
- inflammation in the rectum;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
It is possible to use the drug Corilip during pregnancy and lactation (breast-feeding).
Use in children
The drug is intended for use in children, including infants and newborns. The application is possible according to the dosing regimen specified above.
special instructions
Criteria for the duration of treatment along with the clinical status are the cytochemical indices of the activity of peripheral blood leukocyte enzymes (succinate dehydrogenase and glycerophosphate dehydrogenase).
The differences of Korilip from Korilip Neo consist in a halved dosage of active ingredients in the candles of the preparation of Corilip Neo, which allows using the latter in newborns under 1 year in a convenient dosage form and not divide the candles in half.
Drug Interactions
Negative interaction was not observed. The drug can be used for complex therapy.
Analogues of the drug Corilip
Structural analogs for the active substance:
- Corilip Neo.
Analogues on the curative effect (remedies for the elimination of immunodeficiency):
- Shark cartilage;
- Alisat;
- Allikor;
- Ampholip;
- Arbidol;
- Arthromax;
- Bactistatin;
- Betulanorm;
- Vazoton (L-arginine);
- Vetoron;
- Galavit;
- Glutoxim;
- Groprinosin;
- Detrikan;
- Immunal;
- Immunoglobulin;
- Immunomax;
- Immunomyshki;
- Imunofan;
- Intraglobin;
- Beresz Plus drops;
- Cardioies;
- Carinate;
- Lamisplat;
- Lysite (L-Lysine);
- Lycopid;
- Myelopid;
- Neovir;
- Normoflorin;
- Octagam;
- OrtoImmun;
- Panavir;
- Pentaglobin;
- Polyoxidonium;
- Privyzhen;
- Ribasan forte;
- Roncoleicin;
- Tamerite;
- Timalin;
- Timogen;
- Timodepressin;
- Timoptin for injection;
- Timusamine;
- Trekrezan;
- Humaglobin;
- Cerebrum compositum H;
- Cycloferon;
- Cytotect;
- Eifitol;
- Engistol;
- Endobulin.