Dekasan - instructions for use, analogs, reviews and release forms (a solution of 0.02% for an inhaler or nebulizer, external use in the form of lotions and washes) drugs for the treatment of inflammation in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Dekasan. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Dekasan in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Dekasan in the presence of existing structural analogs.Use for the treatment of fungal and infectious diseases and concomitant inflammation in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Dekasan - fungicidal, antifungal, virusicidal and antimicrobial. The mechanism of action of Dekasan is based on its ability to disrupt the permeability of the cell membrane (CM) of the target, by combining with lipid structures in the region of their phosphatide groups. As a result of changes in CM permeability, homeostasis within cells is disrupted, and cell lysis occurs. The selectivity of Dekasan's action is manifested in the inability to concentrate on the CM of human cells.

The bactericidal action of Dexasan on most strains of gram-positive and gram-negative microorganisms was studied and confirmed. Among them are staphylococci, streptococci, causative agents of diphtheria, Pseudomonas aeruginosa, and others. The fungicidal action of Dexasan is manifested in relation to epidermophytes, trichophytes, yeast-like fungi, erythrasma, yeast, some mold-like fungi (penicillas, aspergilla). Antiprotozoal efficacy Dekasan shows against lamblia and trichomonads.There are no stable viruses to action of the drug. The bacteriostatic effect of Dexasan is due to the same mechanism of action and can be considered as the first stage of bactericidal manifestation.

During the treatment, Dekasan increases the sensitivity of microorganisms to antibiotics, and shows its activity towards strains that have been resistant to the treatment. Undamaged mucous membranes and skin interfere with the absorption of the drug. In the blood of significant concentrations of Dekasan was not detected.

Composition

A solution of 0.02% decamethoxin in an isotonic sodium chloride solution.

Indications

• skin diseases (bacterial, pustular and fungal, microbial eczema);
• purulent-inflammatory diseases of the skin and subcutaneous tissue in the stage of open wounds and drainage (furuncle, carbuncle, panaritium, phlegmon, abscess, infected wounds, etc.);
• inflammatory diseases of the oral cavity (gingivitis, stomatitis, paradontitis);
• severe inflammatory diseases of the respiratory system and their complications (suppurative bronchiectasis, abscessed cystic lung hypoplasia, exacerbation of chronic bronchitis);
• inflammatory diseases of the upper respiratory tract (angina, chronic laryngopharyngitis, bacterial carriage);
• inflammation of the large intestine (sigmoiditis, proctitis, ulcerative colitis);
• inflammation of the urogenital area (urethritis, balanoposthitis, prostatitis, vaginitis, endometritis);
• for irrigation of the abdominal and pleural cavity in surgery;
• apply in the pre-sterilization treatment of medical instruments and equipment;
• sanation of the birth canal in pregnant women before childbirth;
• disinfection of hands and gloves of medical personnel, before manipulation and surgical treatment.

Forms of release

A solution of 0.02% in a vial or a polymer container.

There are no other dosage forms, be it ointment or tablets.

Instructions for use and how to use them

In ordinary form, Dekasan is used to treat skin diseases in the form of lotions and washes. In fistulous forms of the disease, daily rinsing through the fistulas is used. The course of treatment is up to 5 days.

In urological practice for the treatment of chronic urethritis and cystitis, Dekasan is previously diluted 1: 7 with clean water, at a rate of up to 600 ml for 20 washes (treatment course).For the treatment of diseases of the large intestine and prostatitis, the heated solution is injected with enema 2 times a day for 100 ml, until the symptomatology, which is characteristic for the exacerbation of the process, disappears completely.

With diseases of the oral mucosa, Dekasan is used in the form of rinses of 150 ml or applications up to 50 ml, for 12-15 minutes. With periodontal disease of the 1-2 degree of the dystrophic inflammatory course, in the period of exacerbation of the process, the pockets of the gums are irrigated with a warm solution of the drug (about 100 ml) or applications are applied to the affected gums until relief of acute manifestations of inflammation. Ulcerative necrotic gingivitis and candidiasis of the oral mucosa, require rinsing 4-5 times a day, 150 ml each. The course of treatment is about 10 days.

In fungal lesions of palatine tonsils and chronic tonsillitis, as well as asymptomatic carriage of pathogenic bacteriological flora, lacunas of palatine tonsils and pharynge are washed or rinsed, using about 100 ml of Dekasan for 1 rinse. It is advisable at the same time to carry out irrigation of the nasopharynx.

Special care and caution requires endobronchial use of Dexan in cases of suppurative bronchiectasias, abscessed cystic lung hypoplasia, exacerbations of chronic bronchitis.Depending on the method of administration of the drug, the following dosage and multiplicity of administration is recommended:

• Microtraeostomal route of administration - up to 50 ml 2 times a day.
• Transnasal catheter - up to 10 ml 1 time per day.
• Ultrasonic inhalation (inhaler or nebulizer) - up to 10 ml 1-2 times a day.
• By tracheobronchial lavage - up to 100 ml.

The duration of therapy is from 2 weeks to 1 month.

When treating bacterial, trichomonas and mycotic vaginitis Dekasan is used by douching. The drug is heated to +38 degrees Celsius and injected in a volume of up to 100 ml 3 times a day. Similarly, a single prenatal sanation of the future birth canal of a pregnant woman is carried out. For relief of endometritis, in the postpartum period, rinsing of the uterine cavity is used, 2 times a day, with a warm solution of Dekasan, in a volume of up to 200 ml.

Disinfection of the hands and gloves of medical personnel before manipulation and surgical treatment is carried out by treating a sufficient amount of Dexan for at least 5 minutes. Pre-cleaned diagnostic and medical instruments are immersed in the drug solution for 30 minutes for disinfection.

Side effect

• local manifestations of allergies in the form of redness of the skin, hives;
• The endobronchial way of Dekasan administration causes a feeling of heat and burning behind the sternum (these symptoms pass independently for half an hour after the procedure).

Contraindications

• individual intolerance of the drug components.

Application in pregnancy and lactation

During pregnancy or lactation (breast-feeding) there are no contraindications to the use of Dekasan. It does not penetrate the skin and mucous membranes into the body of a woman.

Use in children

Use in children has not been studied.

special instructions

Dekasan does not cause toxic effects. However, before applying the drug for cavitary irrigation and in endobronchial practice, it is advisable to conduct skin tests for individual sensitivity to the drug.

Heated to +38 degrees Celsius Dekasan has a more effective effect.

Drug Interactions

Decassane has cationic surface-active properties and is therefore incompatible with substances exhibiting anionic activity (soap, etc.).

The drug increases the sensitivity of resistant strains of microflora to antibiotics.

Analogues of the drug Dekasan

Structural analogs for the active substance:

• Decamethoxin.

Analogues on the curative effect (means for treating cough):

• Alex Plus;
• Antussin;
• Biolin Cold;
• Bromhexine;
• Bronchalamine;
• Bronhalis Hel;
• Bronchicum;
• Bronchicum cough lozenges;
• Bronchicum cough syrup;
• Bronchipret;
• Broncholitin;
• Bronhosan;
• Hexapneumine;
• Herbion syrup of plantain;
• Glycodine;
• Chest fee;
• Insty;
• Carbocysteine;
• Kodelak;
• Codterpine;
• Broncho's Witchcraft;
• Coldrex;
• Levopron;
• Libexin;
• Linkas;
• Metovit;
• Mukaltin;
• Omnitus;
• Pectusin;
• Pulmeks;
• Sinecod;
• Stoptussin;
• Travisil;
• Tussin;
• Tusuprex;
• Falimint;
• Fervex from a dry cough;
• Eucabal;
• Eladon;
• Erespal.

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