Mebendazole - instructions for use, reviews, analogs and forms of release (100 mg tablets) for the treatment of worms (ascariasis, enterobiasis and others) in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Mebendazole. There are reviews of visitors to the site - consumers of this medication, as well as opinions of medical specialists on the use of Mebendazole in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Mebendazole in the presence of existing structural analogues. Use to treat worms (ascariasis, enterobiasis and others) in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Mebendazole - an anthelmintic agent of a wide spectrum of action; most effective in enterobiosis. Causes irreversible disruption of glucose utilization in the helminth organism and inhibits the synthesis of ATP.

Composition

Mebendazole + auxiliary substances.

Pharmacokinetics

Virtually not absorbed from the digestive tract. Binding to plasma proteins is 90%. Unevenly distributed in the organs, accumulates in adipose tissue, liver, larvae of helminths. In the liver, it is metabolized to a 2-amino derivative. More than 90% of the dose is excreted with feces unchanged. The absorbed part (5-10%) is excreted by the kidneys.

Indications

• enterobiosis;
• ascaridosis;
• ankylostomidosis;
• strongyloidiasis;
• trichocephalus;
• trichinosis;
• shadows;
• echinococcosis;
• alveococcosis;
• capillarial disease;
• gnathostomosis;
• mixed helminthiases.

Forms of release

Tablets of 100 mg.

Instructions for use and dosing regimen

Adults and children older than 10 years with enterobiosis - in a dose of 100 mg once.

Children aged 2 to 10 years - in a dose of 25-50 mg once. In the case of a high probability of repeated invasion, the dose is repeated after 2-4 weeks at the same dose.

It is recommended that all members of the family be treated at the same time.

With ascariasis, trichocephalosis, ankylostomiasis, teniosis, strongyloidiasis and mixed helminthiasis - 100 mg in the morning and in the evening for 3 days. In trichinosis, 200-400 mg three times a day for 3 days, and from the 4th to the 10th day, 400-500 mg 3 times a day. When echinococcosis - 500 mg twice a day for the first 3 days, then in the same dose 3 times a day for the next 3 days. In the future, apply in a dose of 25-30 mg / kg per day in 3-4 divided doses.

Side effect

• nausea, vomiting;
• stomach ache;
• diarrhea;
• dizziness;
• headache;
• leukopenia, anemia, eosinophilia;
• hematuria;
• cylindruria;
• allergic reactions;
• hair loss.

Contraindications

• severe liver dysfunction;
• pregnancy;
• lactation (breastfeeding);
• children under 2 years;
• increased sensitivity to mebendazole.

Application in pregnancy and lactation

Mebendazole is contraindicated in pregnancy and lactation (breast-feeding).

Use in children

Contraindicated in children under 2 years.

special instructions

With prolonged use, it is necessary to monitor the picture of peripheral blood, liver and kidney function.

During the day after taking mebendazole, avoid drinking alcohol.

After taking mebendazole, do not use a laxative.

Periodic examination of anal and feces smears after the end of treatment is mandatory (therapy is considered effective in the absence of helminths or their eggs for 7 consecutive days).

Drug Interactions

Mebendazole reduces the need for insulin in patients with diabetes mellitus.

Combination of mebendazole with lipophilic substances should be avoided. With simultaneous use of cimetidine can increase, and Carbamazepine and other inducers of metabolism - to reduce the concentration of mebendazole in the blood.

Analogues of the medicinal product Mebendazole

Structural analogs for the active substance:

• Vermox;
• Vero Mebendazole;
• Worming;
• Telmox 100.

Analogues for the pharmacological group (anthelmintics):

• Albendazole;
• Biltricide;
• Vermox;
• Vero Mebendazole;
• Worming;
• Gelmodol BM;
• Helmintox;
• Decaris;
• Nemosol;
• Nemocide;
• Piperazine;
• Piperazine adipate;
• Pirantel;
• Pirantela pamoat;
• Piervinium;
• Sanoxal;
• Telmox 100.

Similar medicines:

Other medicines: