Clenzite - instructions for use, analogs, reviews and release forms (gel, cream or ointment for external use 0.1% C) of the drug for the treatment of acne (acne) in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Clenzite. Comments of visitors of the site - consumers of this medicine, as well as opinions of doctors of specialists on the use of Clenzite in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Clenzite in the presence of existing structural analogs. Use to treat acne (acne) in adults, children, as well as during pregnancy and lactation.Composition of the preparation.

Clenzite - preparation for external use.

Adapalene (the active substance of the drug Klensit) is a metabolite of the retinoid, has a comedonolytic and anti-inflammatory effect, normalizes the processes of keratinization and epidermal differentiation.

The mechanism of action of adapalene is based on interaction with specific gamma-receptors of skin epidermal cells. As a result of the action of adapalene, in particular, the "cohesion" of epithelial cells in the mouth of the sebaceous-hair follicle decreases and the preconditions for the formation of micro-comedones decrease.

Clenzite has an anti-inflammatory effect, affecting the inflammatory factors by inhibiting the migration of leukocytes in the inflammatory focus and the metabolism of arachidonic acid.

Clindamycin (the active substance of the drug Clenzite C) is a bacteriostatic antibiotic from the group of lincosamides, has a wide spectrum of action, binds to the 50S subunit of the ribosomal membrane and suppresses protein synthesis in the microbial cell. With respect to a number of gram-positive cocci, a bactericidal effect is possible. There is a cross-resistance between Clindamycin and linkomycin.

Composition

Adapalene + auxiliary substances.

Adapalene (micronized) + Clindamycin (in the form of phosphate) + excipients (Clindamycin C).

Pharmacokinetics

Absorption of adapalene through the skin is very low (about 4% of the applied dose). Derivation of adapalene from the body occurs mainly with bile.

Indications

• acne (acne).

Forms of release

Gel for external use 0,1% (sometimes mistakenly called ointment or cream).

Gel for external use (Clenzite C).

Instructions for use and how to use them

Outwardly. Before applying the gel, it is necessary to clean and dry the skin of the face. With a gentle touch, apply the gel uniformly to the affected area 1 time per day before bedtime, avoiding getting the drug on the mucous membranes of the eyes and lips.

The therapeutic effect develops after 4-8 weeks of treatment, persistent improvement occurs after a 3-month treatment. In some cases, due to short-term skin irritation, treatment can be suspended until the symptoms of irritation disappear.

Repeated treatment is possible after consultation with a doctor.

Cylinder C

Outwardly. Before applying the gel, you need to clean and dry the skin.With a light touch, apply the gel evenly to the affected areas of the skin 1 time per day before bedtime. Avoid getting the drug on the mucous membranes of the eyes, lips.

The course of treatment is from 2 to 4 weeks. Repeated treatment is possible after consultation with a doctor.

Side effect

• skin irritation (treatment should be stopped until skin irritation disappears or frequency of application is reduced);
• hyperemia of the skin;
• peeling of the skin in the place of application;
• burning sensation.

Contraindications

• pregnancy;
• lactation period (breastfeeding);
• hypersensitivity to the components of the drug.

Application in pregnancy and lactation

It is not recommended to use the drug during pregnancy and lactation (breastfeeding).

special instructions

If you accidentally get the drug on the mucous membranes of the eyes, mouth or nose, you must thoroughly wash them with warm water.

Avoid direct sunlight, as skin irritation may occur. Treatment can be continued if solar exposure is minimized through the use of sunglasses and hats.

With caution should be used drug for dermatitis, eczema.

It is not recommended simultaneous use of cosmetic products with drying and irritating effect on the skin (for example, perfume or ethanol-containing products).

Adapalene, applied to the skin in the evening, can be combined with drugs for the treatment of blackheads, applied in the morning.

Do not use gel to treat damaged skin and burns.

Drug Interactions

Since ClenSit does not interact with oxygen and does not break down under the influence of light, it is possible to simultaneously treat acne with drugs such as clindamycin phosphate or benzoyl peroxide.

Clenzite C is incompatible with solutions containing a complex of B vitamins, aminoglycosides, ampicillin, Calcium gluconate and magnesium sulfate.

Analogues of the drug Clenzite

Structural analogs for the active substance:

• Adaclin;
• Adapalen;
• Adolen;
• Differin.

Analogues for the pharmacological group (remedies for acne):

• Acnekutan;
• Androkur;
• Arthromax;
• Basiron AC;
• Balian;
• Bassado;
• Bellune 35;
• Betusil;
• Biseptol;
• Wilprafen;
• Wilprafen solute;
• Delex Acne gel from acne;
• Deleks Acne cleansing lotion;
• Desquam;
• Jess;
• Jess Plus;
• Diane 35;
• Dimephosphone;
• Doxal;
• Doxycycline;
• Dr. Theiss Acne Cream for acne;
• Dr. Theiss Acne Acne Lotion;
• Yeast beer;
• Mirror;
• Zinerit;
• Curious;
• Kutis compositus;
• Purge of Puree;
• Metronidazole;
• Microfolline;
• Monoclin;
• Piolizin;
• Proderm;
• Roaccutane;
• Rosamet;
• Roxithromycin Lek;
• Skinoren;
• Streptonitol;
• Chloe;
• Cytale;
• Edas;
• Eplan;
• Unidox Solutab;
• Yarina Plus.

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