Furamag - instructions for use, reviews, analogs and forms of release (capsules or tablets of 25 mg and 50 mg) drugs for the treatment of cystitis, urethritis and pyelonephritis in adults, children and pregnancy. Interaction with alcohol

In this article, you can read the instructions for using the drug Furamag. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Furamaga in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Furamag with available structural analogues. Use for the treatment of cystitis, urethritis and pyelonephritis in adults, children, as well as in pregnancy and lactation. Interaction of the drug with alcohol.

Furamag - a broad-spectrum antimicrobial agent belonging to the group of nitrofurans.

Resistance to Furamago develops slowly and does not reach a high degree.

It is active against gram-positive cocci, gram-negative rods, protozoa and other microorganisms resistant to antibiotics.

With respect to Staphylococcus spp., Escherichia coli, Aerobacter aerogenes, Bacterium citrovorum, Proteus mirabilis, Proteus morganii, Furamag, in comparison with other nitrofurans, is more active.

Under the influence of nitrofurans in microorganisms, the respiratory chain and the cycle of tricarboxylic acids (Krebs cycle) are suppressed, as well as the inhibition of other biochemical processes of microorganisms, as a result of which their shell or cytoplasmic membrane is destroyed.

As a result of the action of nitrofurans, microorganisms produce fewer toxins, so that the improvement of the patient's general condition is possible even before the expressed suppression of microflora growth. Nitrofurans activate the immune system of the body: increase the complement titer and the ability of leukocytes to phagocytose microorganisms. Furazidine in therapeutic doses stimulates leukopoiesis.

Composition

Furazidine (in the form of potassium salt) + auxiliary substances.

Pharmacokinetics

After taking the drug inside, Furamag is absorbed in the small intestine by passive diffusion. Absorption of nitrofurans from the distal segment of the small intestine exceeds the absorption from the proximal and medial segments by 2 and 4 times, respectively (should be taken into account in the simultaneous treatment of urogenital infections and gastrointestinal diseases, in particular chronic enteritis). Nitrofurans are poorly absorbed from the large intestine. Being a mixture of the potassium salt of furazidine and magnesium carbonate basic in a ratio of 1: 1, Furamag, when administered orally, has a higher bioavailability than simple furazidine (after taking Furamag capsule in an acidic stomach, there is no conversion of potassium furozidine to poorly soluble furazidine). In the body, furazidine is distributed evenly. Clinically important is the high content of the drug in the lymph (delaying the spread of infection through the lymphatic ways). In bile, its concentration is several times higher than in serum, and in cerebrospinal fluid it is several times lower than in serum. In saliva, the content of furazidine is 30% of its serum concentration.The concentration of furazidine in the blood and tissues is relatively small, which is due to its rapid release, while the concentration in the urine is much higher than in the blood. It is excreted by the kidneys by glomerular filtration and tubular secretion (85%), partially subjected to reverse reabsorption in tubules.

Indications

Infections caused by susceptible microorganisms:

• urogenital infections (acute cystitis, urethritis, pyelonephritis);
• gynecological infections;
• infections of the skin and soft tissues;
• severe infected burns;
• with the preventive purpose at urological operations (including a cystoscopy, a catheterization).

Forms of release

Capsules 25 mg and 50 mg (sometimes mistakenly called tablets).

Instructions for use and dosage

The drug should be taken orally after a meal.

Adults appoint 50-100 mg 3 times a day.

Children are prescribed 25-50 mg 3 times a day (but not more than 5 mg / kg of body weight per day).

The course of treatment is 7-10 days. If it is necessary to repeat the course of treatment, you should take a break for 10-15 days.

To prevent infection (including urological operations, cystoscopy, catheterization), the drug is prescribed to adults 50 mg each, children - 25 mg once for 30 minutes before the procedure.

If you miss the drug, the next dose should be taken at the usual time.Do not take twice the dose to compensate for the missed dose.

Side effect

• nausea, vomiting;
• loss of appetite;
• impaired liver function;
• headache;
• dizziness;
• skin rash (including papular rashes).

Contraindications

• chronic renal failure of a serious degree;
• pregnancy;
• lactation period (breastfeeding);
• children under 3 years (for capsules);
• increased sensitivity to nitrofuran group drugs.

Application in pregnancy and lactation

Contraindicated use of the drug during pregnancy and lactation (breastfeeding).

special instructions

To reduce the likelihood of side effects Furamag washed down with a lot of fluid.

If side effects occur, the drug should be discontinued (toxic effects are more frequent in patients with reduced renal excretory function).

The patient should inform the doctor of any side effects that occur during treatment with the drug.

During the period of treatment, the patient is advised to refrain from drinking alcohol and alcoholic beverages, since side effects are likely to increase.

Drug Interactions

Do not apply Furamag along with ristomycin, chloramphenicol, sulfonamides (increases the risk of oppression of hematopoiesis).

It is not recommended simultaneously with nitrofurans to prescribe drugs that can acidify urine (including ascorbic acid, calcium chloride).

Analogues of the drug Furamag

Structural analogs for the active substance:

• Furagin;
• Furazidine;
• Furamag;
• Furasol.

Similar medicines:

Other medicines: