L methionine - instructions for use, analogs, testimonials and release forms (250 mg tablets) for the treatment of hepatitis, hepatosis and cirrhosis in adults, children and pregnancy

In this article, you can read the instructions for using the drug L methionine. Presented are reviews of visitors to the site - consumers of this medication, as well as the opinions of physicians specialists on the use of L methionine in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of L methionine in the presence of existing structural analogs. Use for the treatment of hepatitis, hepatosis and cirrhosis of the liver in adults, children, as well as during pregnancy and lactation.

L methionine - an indispensable amino acid, necessary to maintain growth and Nitrogen balance of the body. Contains a methyl group that participates in the process of re-methylation and is necessary for the synthesis of choline. Due to this, normalizes the synthesis of phospholipids from fats and reduces the deposition in the liver of neutral fat.

Participates in the exchange of sulfur-containing amino acids, in the synthesis of epinephrine, creatinine and other biologically active substances, activates the action of hormones, Vitamins (B12, ascorbic, folic acid), enzymes, proteins, re-methylation reactions, deamination, decarboxylation. It is necessary for detoxification of xenobiotics.

When atherosclerosis reduces the concentration of cholesterol and increases the concentration of blood phospholipids.

Indications

Diseases of the liver that occur with fatty infiltration of hepatocytes:

• toxic hepatitis;
• hepatosis (including alcohol);
• cirrhosis;
• hepatic dystrophy;
• intoxication.

In the combination therapy:

• deficiency of protein of different origin;
• atherosclerosis;
• diabetes.

Prevention of toxic liver damage by arsenic, chloroform, benzene, alcohol.

Forms of release

Tablets 250 mg.

Instructions for use and dosing regimen

Adults-500 mg-1500 mg 3-4 times a day.

Single doses for children under 1 year - 100 mg, at the age of 1-2 years - 200 mg, at the age of 3-4 years - 250 mg, at the age of 5-6 years - 300 mg, at the age of over 7 years - 500 mg; the frequency of reception is 3-4 times a day.

Take 1 / 2-1 hour before meals. The course of treatment is 10-30 days or 10 days with 10-day intervals.

Side effect

• allergic reactions;
• nausea, vomiting (due to unpleasant odor and taste).

Contraindications

• hypersensitivity to methionine;
• severe hepatic impairment;
• hepatic encephalopathy;
• viral hepatitis.

Application in pregnancy and lactation

Data on the effect of the drug on the body during pregnancy and lactation are absent. Use of the drug requires caution in use.

Use in children

The application is possible according to the dosing regimen.

special instructions

Use with caution in renal failure (the risk of an increase in hyperaemia).

When methionine is used in patients with atherosclerosis, a decrease in the cholesterol content in the blood and an increase in the level of phospholipids are noted.

It should be prescribed in balance with other amino acids. Unbalanced use of methionine in large doses can have a damaging effect on liver cells and other organs.

Drug Interactions

With simultaneous application with levodopa, its effectiveness decreases.

Analogues of the drug L methionine

Structural analogs for the active substance:

• D, L-Methionine;
• Methionine.

Analogues for the pharmacological group (hepatoprotectors):

• S-Adenosylmethionine;
• Alpha-lipoic acid;
• Antraliv;
• Berlition;
• Brentzialle forte;
• Vitanorm;
• Hepa-Mertz;
• Hepatosan;
• Heptor;
• Heptral;
• Heptrog;
• Glutargin;
• Covechol;
• Karsil;
• Karsil Forte;
• Cryomelt MN;
• Legalon 140;
• Legal 70;
• Livedoksa;
• Livolife Forte;
• Lipoic acid;
• Maxar;
• Methionine;
• Metrop;
• Milife;
• Moliksan;
• Octolipen;
• Ornitsetil;
• Resalute Pro;
• Silegon;
• Silibinin;
• Sylimar;
• Silymarin;
• Sirepard;
• Thiolipone;
• Tiotriazolin;
• Urdoks;
• Urso 100;
• Ursodez;
• Ursodeoxycholic acid;
• Ursodex;
• Ursuliv;
• Ursor;
• Ursosan;
• Ursofalk;
• Phosphontsiale;
• Hepabos;
• Holudexan;
• Exxhol;
• Erbisol;
• Espa Lipon;
• Essentiale N;
• Essentiale forte N;
• Essential phospholipids;
• The Essler.

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