Donormil - instructions for use, reviews, analogs and forms of release (15 mg tablets, including effervescent soluble) drug for the treatment of sleep disorders and insomnia in adults, children and pregnancy. Addiction and interaction with alcohol
In this article, you can read the instructions for using the drug Donormil. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Donormil in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues Donormila in the presence of existing structural analogues.Use to treat sleep disorders and insomnia in adults, children, as well as during pregnancy and lactation. Addiction and interaction of the drug with alcohol.
Donormil - blocker of H1-histamine receptors from the group of ethanolamines. The drug has a hypnotic, sedative and M-anticholinergic action. Reduces the time of falling asleep, increases the duration and quality of sleep, while not changing the phase of sleep. The duration of the action is 6-8 hours.
Composition
Doxylamine succinate + excipients.
Pharmacokinetics
Absorption is high, metabolized in the liver. It penetrates well through the histohematological barriers (including the blood-brain barrier). It is excreted by 60% kidneys in an unchanged form, partially through the digestive tract.
Indications
- sleep disturbance, insomnia.
Forms of release
Tablets effervescent soluble 15 mg.
The tablets covered with a cover of 15 mg.
Instructions for use and dosage
The recommended dose is from 1/2 to 1 tablet per day. The tablet is fizzy dissolve in half a glass of water. The coated tablet is inside, with a small amount of liquid. Take 15 minutes before bedtime. If treatment is ineffective,on the recommendation of a doctor, the dose can be increased to two tablets.
Duration of treatment from 2 to 5 days; If insomnia persists, treatment should be reviewed.
Side effect
- drowsiness during the day;
- dry mouth;
- paresis of accommodation;
- constipation;
- retention of urine.
Contraindications
- hypersensitivity to doxylamine or other components of the drug;
- angle-closure glaucoma;
- hyperplasia of the prostate, urinary retention;
- the period of breastfeeding;
- children and adolescence (up to 15 years).
Application in pregnancy and lactation
The drug should be used with caution in pregnancy. Before using the drug, consult your doctor.
Contraindicated during breastfeeding.
special instructions
It should avoid activities that require rapid mental and motor reactions. This drug contains 484 mg of sodium per tablet, which should be taken into account when calculating daily intake for a low-salt diet.
Drug Interactions
With the simultaneous reception of Donormil with barbiturates, benzodiazepines, clonidine, opioid analgesics, antipsychotics,anxiolytics intensifies the inhibitory effect on the central nervous system. May reduce the emetic reaction to apomorphine.
When taken with M-anticholinergic agents, the risk of side effects increases: dry mouth, urinary retention.
Since alcohol enhances the (mutually) sedative effect of Donormil, it is necessary to avoid the use of alcoholic beverages and drugs containing alcohol.
Analogues of the drug Donormil
Structural analogs for the active substance:
- Valocordin-Doxylamine.
Analogues on the therapeutic effect (hypnotics):
- Andante;
- Apo-Flurazepam;
- Berlidorm 5;
- Bromizoval;
- Heminearrin;
- Hypnogen;
- Dormikum;
- Zaleplon;
- Zolpidem;
- Zolsana;
- Zopiclone;
- Iwadal;
- Imovan;
- Melaxen;
- Nitrazadone;
- Nitrazepam;
- Nitram;
- Nitrust;
- Nitrosan;
- Piklodorm;
- Radedorm 5;
- Relaxon;
- Rohypnol;
- Sanvall;
- Signopam;
- Snovitel;
- Somnol;
- Thorson;
- Phenobarbital;
- Flormidal;
- Circadian;
- Estazolam;
- Eunotin.
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