Retinol (acetate and palmitate) - instructions for use, analogs, reviews and release forms (tablets, capsules, dragees, cream, ointment, solution in oil) for the treatment of eczema, dermatitis and other skin problems in adults, children and pregnancy
In this article, you can read the instructions for using the drug Retinol (acetate and palmitate). Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of specialists on the use of Retinol in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Retinol analogues with existing structural analogues.Use to treat eczema, dermatitis and other skin and hair problems in adults, children, as well as during pregnancy and lactation, including in cosmetology.
Retinol - dermatoprotective agent. Stimulates skin regeneration, enhances the division of skin epithelial cells, inhibits keratinization, hinders the development of hyperkeratosis. Local action is due to the presence on the cell surface of the epithelium of specific retinol-binding receptors.
Pharmacokinetics
After application, it easily penetrates the skin. Cmax of active substances in the blood is achieved 3-4 hours after application and is maintained for 12 hours.
Indications
- hypo- and vitamin A vitamin deficiency;
- ichthyosis;
- hyperkeratosis;
- seborrheic dermatitis;
- psoriasis;
- pyoderma;
- atopic dermatitis;
- neurodermatitis;
- eczema;
- frostbite;
- burns;
- erosion;
- ulcers;
- cracks;
- lupus;
- atrophy of the skin after prolonged use of glucocorticosteroids.
Forms of release
Pills.
Capsules.
Dragee.
Cream.
Ointment.
Solution for oral administration oil 3.44%.
Instructions for use and how to use them
Inside, intramuscularly, externally. Treatment doses for avitaminosis of light and medium degree: adults - up to 33000 IU / day, with eye diseases (hemeralopia, xerophthalmia, pigment retinitis) - 50000-100000 IU / day. Children - 1000-5000 IU / day, depending on the age. With skin diseases: adults - 50000-100000 IU / day, children - 5000-10000-20000 IU / day. Oily solutions can also be applied externally for burns, ulcers, frostbites, lubricating 5-6 times a day and covering with a gauze dressing; At the same time retinol is administered orally or intramuscularly.
Outwardly. Ointment is applied a thin layer on the affected skin areas 2 times a day, early in the morning and late at night. With strong peeling of the skin - under the occlusive bandage. Duration of use is 4-12 weeks.
Side effect
- increased itching;
- hyperemia;
- allergic reactions.
Contraindications
- hypervitaminosis A;
- 1 trimester of pregnancy;
- acute inflammatory skin diseases;
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
The drug is contraindicated for use in the first trimester of pregnancy.
In the period of lactation (breastfeeding) is not recommended to apply to the skin of the mammary glands.
External application of retinol during pregnancy and breastfeeding is possible,if the expected effect of therapy exceeds the potential risk to the fetus and the baby.
special instructions
Do not recommend to use for the treatment of skin dryness, wrinkles, eye diseases, infections not related to vitamin A deficiency.
Drug Interactions
Do not use in combination with other drugs containing vitamin A and retinoids, to avoid hypervitaminosis A.
It is not compatible with Tetracycline antibiotics.
Reduces (mutually) the risk of hypervitaminosis D. Absorption of retinol is disrupted by nitrites, colestyramine, colestipol, neomycin (by mouth).
Analogues of the drug Retinol
Structural analogs for the active substance:
- Let's see;
- Vitamin A;
- Vitamin A acetate;
- Vitamin A-palmitate is an oily form;
- Vitamin A-acetate is an oily form;
- Retinol acetate;
- Retinol acetate (Vitamin A);
- Retinol acetate-Rusfar;
- Retinol acetate solution in oil;
- Retinol acetate solution for injection in oil;
- Retinol acetate acetate coated tablets 0.01135 g (Vitamin A 33000 IU);
- Retinol palmitate;
- Retinol palmitate solution in oil;
- Sanvit A 1.7 million IU / g Palmitate oily form.
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