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Xidiphon - instructions for use, analogs, reviews and release forms (a solution of 20% - 2%) of the drug for the treatment and regulation of calcium metabolism, with urolithiasis in adults, children and pregnancy

Xidiphon - instructions for use, analogs, reviews and release forms (a solution of 20% - 2%) of the drug for the treatment and regulation of calcium metabolism, with urolithiasis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Xidifon. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Xidifon in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogs of Xidiphon with existing structural analogues. Use for the treatment and regulation of calcium metabolism (with urolithiasis, osteoporosis) in adults, children, as well as during pregnancy and lactation.

 

Xidifon - a drug that regulates calcium metabolism. Prevents excessive calcium output from the bones, thereby preventing osteoporosis, prevents pathological calcification of soft tissues.

 

The drug prevents crystal formation, as well as the growth and aggregation of crystals of calcium salts in the urine. Keeping the calcium ions in a dissolved state, Xidiphone prevents the recurrence of stones, eliminating the possibility of formation of insoluble calcium salts (with oxalates, mucopolysaccharides, phosphates, etc.), has a moderate anti-inflammatory effect in interstitial nephritis.

 

Xidiphon, like other complexing compounds, has the property of accelerating the excretion of heavy metals - lead, tin, antimony, strontium, magnesium, silicon. Does not disturb the balance of microelements.

 

Also confirmed the effectiveness of the use of Xidifon in the complex therapy of bronchial asthma. In this case, the mechanism of the action of Xidiphon is not fully understood. It is assumed that it changes the biophysical state of the membranes of immunocompetent cells, stabilizing them.

 

Pharmacokinetics

 

Absorbed from the stomach during the first 30 minutes after ingestion. In the body, it is not metabolized and is excreted unchanged in the main with urine.

 

Indications

  • to accelerate the removal from the body of excess heavy metals of lead, tin, strontium, silicon and antimony;
  • in the complex therapy of bronchial asthma of the lung and moderate course in adults with the goal of stabilizing the membranes of immunocompetent cells;
  • in the complex therapy of hormone-dependent bronchial asthma in adults with the goal of preventing osteoporosis.

 

As a means of regulating calcium metabolism in adults and children:

  • with urolithiasis and other kidney diseases;
  • with hyperavitaminosis D;
  • with hyperparathyroidism and concomitant interstitial nephritis;
  • for the treatment and prevention of osteoporosis;
  • as a means of preventing the development of osteopenia and osteoporosis with prolonged immobilization of patients with rheumatoid arthritis, which increases bone mass in secondary osteoporosis.

 

Forms of release

 

A solution of 20% for the preparation of a 2% solution for oral administration.

 

Instructions for use and dosage

 

Xidiphon is taken orally 30 minutes before meals, in the form of diluted to 2% solution,which is obtained by adding to the 1 part of the base 20% solution 9 parts of distilled or boiled water (for example, to 50 ml of 20% solution is added 450 ml of water), the diluted solution is stored in the refrigerator.

 

Adults and children over 10 years of age are prescribed 300 mg (1 tablespoon) 2-3 times a day.

 

Children from 3 to 10 years - 200 mg (1 dessert spoon) 2-3 times a day.

 

Children under 3 years - at the rate of 10 mg / kg body weight (1 tsp) 2-3 times a day.

 

The primary course of treatment is 14 days. With crystalluria and the presence of concrements in the kidneys, 5-6 courses are conducted with three-week breaks for 1-2 years. To prevent the recurrence of stone formation, the drug is prescribed up to 2-6 months.

 

For the treatment and prevention of osteoporosis, Xidiphon is used at a dose of 5-7 mg / kg for 2-3 months, after 1-2 months. treatment courses are repeated.

 

In trabecular osteoporosis and osteopenia in patients with rheumatoid arthritis, Xidiphon is used for at least a year at a rate of 5-10 mg / kg body weight in 2 divided doses. At the same time, it is recommended to eat foods rich in calcium salts (equivalent to 500 ml of milk), or, if for some reason, it is impossible, to take Calcium gluconate 1.5 g per day.

 

When chronic intoxication with heavy metals and when residing in theadverse environmental conditions for heavy metals, the use of Xidiphon in a dose of 10 mg / kg of body weight for 7-10 days of each month is recommended.

 

In bronchial asthma, Xidiphon is used in complex therapy in adults over 16 years for no more than 30 days.

 

Side effect

  • laxative effect;
  • hypomagnesemia and rachitis-like effect;
  • change lipid peroxidation, which is eliminated by taking 3-5 drops of a 5% vitamin E oil solution 1 time per day.

 

Contraindications

  • hypocalcemia;
  • pregnancy;
  • lactation period (breastfeeding);
  • hypersensitivity to the drug.

 

Application in pregnancy and lactation

 

The drug is contraindicated for use in pregnancy and lactation.

 

It is not established whether etidronic acid (active ingredient of Xidiphon preparation) is excreted in breast milk.

 

special instructions

 

With caution apply the drug in patients with chronic enterocolitis.

 

When used in patients with reduced renal function, the dosage regimen should be adjusted.

 

Patients taking Xidiphon should receive a sufficient amount of calcium and vitamin D.

 

Drug Interactions

 

The drug interaction of the drug Xidiphone is not described.

 

Analogues of the drug Xidifon

 

Structural analogs for the active substance:

  • Mono-potassium salt of 1-hydroxyethylidene diphosphonic acid dihydrate;
  • Phosphotech.

Similar medicines:

Other medicines:
Reviews (34):
Guests
Tatyana
Xidiphon was assigned to my child, I am very confused that it is used for hyperparathyroidism, and we have hypoparathyroidism, I am afraid to give.
Administrators
admin
Tatyana, The drug Xidiphon is really prescribed for hyperparathyroidism, this state is the opposite of hypoparathyroidism. So either you have confused you with a diagnosis, or the doctor has got it wrong and you need medical advice. These two states are opposite to each other and are treated with different medications.
Guests
Ludmila Viktorovna
At the son of 28 years ossifying myositis. How is xyliphones used in this case?
Administrators
admin
Ludmila Viktorovna, You need to go to the doctor who will prescribe the treatment. Do not risk your son's health.
Guests
Olya
They appointed him to see that I had high calcium in my blood.
For what?
He should reduce it?
Administrators
admin
OlyaThe question should be asked with the details of the situation, but now it turns out like this: it hurts it - it's treated that way. But based on assumptions, you can answer your question in the affirmative, since Xidiphon reduces the concentration of ionized calcium and normalizes the level of total calcium in the blood. The rest, ask the doctor who has all the tests on hand.
Guests
Olya
Thanks for the answer)))
Can I ask you a question?
About the fact that you should take it half an hour before eating. And if I sometimes get it after, it plays a big role?
Administrators
admin
Olya, Try to take the drugs as prescribed. In this particular case, if these are isolated cases of improper reception of Xidifon, then nothing terrible will happen.
Visitors
Islam Adzhiev
Hello, Lyudmila Viktorovna! This is a serious disease, if you have heard about the site foprussia.ru, then it's good, if not, then go to this site and find the next person there, this is Vladislav Grachev - the official FOP representative on the territory of the Russian Federation.
Administrators
admin
Islam Adzhiev, I left your feedback, may someone else come in handy information.
Guests
Natalia
Will not stomach irritate, it's acid, but I have an exacerbation of gastritis?
Administrators
admin
Natalia, To date, no indication of the negative effect of the drug Xidifon on the stomach or intestinal mucosa has been noted. So, against the background of adequate therapy of exacerbation of your gastritis, this drug can be taken.
Visitors
Valeria
I have a disease - galvanosis. This is when, due to metal crowns, the accumulation of ions of heavy metals in the whole body takes place in the mouth and they must be removed.Crowns all removed and now the doctor says that you need a drug to remove heavy metals in chronic form. Can Xidifon cope with this problem?
Administrators
admin
ValeriaThe meaning in the appointment of Xidifon in your case is. Since this drug is complexing, that is, it binds the salts of heavy metals, which the body can then excrete without obvious harm to itself and without disturbing the balance of microelements (good leaves - poor displays). True, the remedy is not cheap.
Visitors
Valeria
You write that the meaning in my case is with galvanose to take Xidiphon. And as the fact that xidiphon displays salts of heavy metals such as lead, tin, antimony, strontium, magnesium, silicon and no more. It turns out, if I had titanium pins and crowns from other metals, then the xyliphon would not remove them from the body?
Administrators
admin
ValeriaAs for the titanium, your question has stumped.It was necessary to open a directory on occupational diseases, since titanium poisonings are found on an industrial scale among the workers of industries associated with this element. I found nothing comforting, except that symptomatic therapy, the consequences of titanium intoxication, is carried out. That is, it can be argued that there is no specific antidote, and Xidifon is unlikely to help in this situation.

Maybe colleagues from the workshop of occupational diseases and more will say, but this specialty is rare and you need to find just such a specialist if the problem makes itself felt on a significant scale. In my mind, I so much want to believe that after removing the cause, the problem should be solved by itself and the body will withdraw the extra elements without medication. But this is only a theory. In addition, if alloys were used, then it is possible to use Xidiphon as well, since there only those crowns and pins are not added and all this taken together and causes galvanization.
Visitors
Valeria
And which scheme is best for me to drink xyliphones?
Administrators
admin
ValeriaIn the instructions, everything is detailed (there and how to dilute the solution and how to take it), I doubt that someone will appoint you other proportions of application, it is painfully exotic for our latitudes. I understand the appointment you prescribed a doctor, he should have indicated the exact proportions. Without eliminating the cause (metals in the mouth), drinking Xidiphon is useless.
Visitors
Islam Adzhiev
It is better to leave the address of the site for FOP (fibrodysplasia ossifying progressive, Munchheimer's disease) where everyone can find a representative in his region and consult him: http://foprussia.ru/physicians
changed admin
Guests
Igor
Acquired (09.2014) Xidiphone (release month 04.2013). A white substance was found in the bottle neck. Is such formation of by-products (sedimentary type) possible, or is this substance exceptionally extraneous?
Administrators
admin
Igor, Xidiphon can form soluble compounds with calcium salts.In any case, there should not be any impurities in the undiluted and fresh solution. Perhaps the seal of the vial was broken or something else, remotely difficult to understand.
Visitors
julinia81
Good afternoon! To my child 3 years this preparation was prescribed to drink 1 time per day for 6 ml, 1 month and after eating an hour later (we weigh 17 kg). Is it possible to drink it in such a scheme and in such a dosage? Because the instructions prescribe to drink at this age 2-3 times a day and 30 minutes before meals. We have a diagnosis of tubulonephritis.
Administrators
admin
julinia81, I get 8 ml of a ready diluted solution of Xidiphon 3 times a day, so there is still a reserve and the dose for one dose can be considered adequate, but why once a day, it is better to ask the doctor. Your child has a rare kidney condition tubulonephritis, so a narrow specialist - a urologist or nephrologist who examined the child - should deal with the dosage and frequency of the admission, so I can not interfere with this treatment. You can advise you to contact another specialist, if you do not trust, but it will be difficult to parse your case online.
Visitors
julinia81
It turns out in my case, once a day, drinking it will be useless? The nephrologist has appointed or nominated it or him. But at us to all this atopic dermatitis and in June there was an acute pyelonephritis. Is tubulointerstitial nephritis and tubulonephritis one and the same? We have written Tubulointerstitial nephritis.
Administrators
admin
julinia81, This is the same diagnosis. In other respects, the dosage and frequency of admission to a particular child is decided by the doctor. If this appointment was made by a narrow specialist (and the nephrologist is a narrow specialist), then I advise you to follow his recommendations. Still, he is responsible for the treatment and he can think that the child can be prescribed dosages below the minimum limit, perhaps from his experience. The condition is rare, some sources even consider it as a disease.
Guests
Karina
Tell me, please, how is it used in osteoporosis? Very necessary! Does this drug relieve joint pain in osteoporosis?
Administrators
admin
Karina, Yes, Xidiphon is used to regulate calcium metabolism in osteoporosis. With this disease joints do not hurt, it is the pathology of bone tissue. It is advisable to consult a doctor for diagnosis of arthrosis or arthritis, as it is these diseases that cause pain in 90% of cases with inflammation in the joints.
Visitors
MelyashkevichAV
Good afternoon, accidentally gave the child undiluted xidiphon, is it dangerous? What now?
Administrators
admin
MelyashkevichAV, In case of an overdose of Xidiphon (which was most likely to occur in your case), it is possible the appearance and / or intensification of the side effects of the drug noted in the instructions. If within two days you do not observe a child like that, then everything is in order and nothing terrible has happened. Next time try not to allow the wrong dosing or the order of taking this and other medications.
Guests
Olga
In St. Petersburg, there is no Xidiphon in any pharmacy. In reference 003 they said that it can not be ordered.Only consult a doctor for an analog.
Guests
Vitaly Sergeevich
What are kidney stones (oxalates) I know for 30 years. For this reason, 3 times I was in the hospital. 3 years ago I learned about Xidifone. Took in two years as described in the instructions to the drug. Completely dissolved 3 stones in the kidneys. For the first time in 20 years there are no stones in the right kidney and the size in the left stabilized. Awesome drug. But unfortunately, now it is almost not in the pharmacies. They say that there is no manufacturer at the factory either. Very, very sorry.
Guests
Natalia Vladimirovna
My daughter was assigned a xylophone. She has a dysmetabolic pyelonephritis, urine tests often show oxalates, and now phosphates. Unfortunately, this drug is not available in pharmacies and it can not be ordered. Are there any analogues of this drug?
Administrators
admin
Natalia VladimirovnaFrom the direct analogues of Xidifon, unfortunately, there is nothing to offer. There is Phosphotech, but it represents a connection with technetium and is used in diagnosis, but not treatment.So discuss with the attending physician of the child than it is possible to replace the analogues of adjacent groups with the desired but not found drug.
Guests
Andrei
For at least a year, the issue of Xidifon was shut down and there is nowhere its analogs, either. It's normal, yes! On a huge country nothing became .....

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