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Hemodez - instructions for use, reviews, analogs and forms of release (solution for infusion 100 ml, 200 ml, 250 ml, 400 ml and 500 ml H and 8000) drugs for the treatment of shock conditions, poisoning, intoxications in adults, children and pregnancy . Composition

Hemodez - instructions for use, reviews, analogs and forms of release (solution for infusion 100 ml, 200 ml, 250 ml, 400 ml and 500 ml H and 8000) drugs for the treatment of shock conditions, poisoning, intoxications in adults, children and pregnancy . Composition

In this article, you can read the instructions for using the drug Hemodez. Presented are reviews of visitors to the site - consumers of this medication, as well as the opinions of doctors specialists on the use of Hemodesis in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogies of Hemodesis in the presence of existing structural analogues. Use for the treatment of shock conditions, intoxications, intoxications in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

 

Hemodez - detoxifying agent. The effect of the drug is due to the ability of low molecular weight polyvinylpyrrolidone to bind toxins circulating in the blood and quickly remove them from the body. The most fully binds toxins circulating in the blood of patients with dysentery, salmonella, food intoxication. With burn disease, the toxins formed in the first 4-5 days of the disease are almost completely inactivated; toxins formed at a later date are much less neutralized. Toxins formed in the body of patients with acute radiation sickness do not bind, although it is possible to accelerate their excretion from the body.

 

Composition

 

Povidone (polyvinylpyrrolidone) low molecular weight medical + Sodium chloride + Potassium chloride + Calcium chloride + Sodium bicarbonate + Magnesium chloride anhydrous + excipients.

 

Pharmacokinetics

 

Metabolism in the body is not affected. Quickly excreted by the kidneys, within 4 hours - 80%, after 12-24 hours - completely.

 

Indications

  • shock (post-traumatic, postoperative, burn, hemorrhagic);
  • intoxication (toxic diseases of the digestive tract, including dysentery, dyspepsia, salmonellosis, burn, radiation and hemolytic disease,peritonitis, intestinal obstruction, thyrotoxicosis, liver disease, sepsis, pneumonia; acute phase of myocardial infarction);
  • toxemia of newborns;
  • gestosis (late toxicosis of pregnant women).

 

Forms of release

 

Solution for infusion or injection in vials of 100 ml, 200 ml, 250 ml, 400 ml and 500 ml (Haemodesum H and 8000).

 

Instructions for use and dosing regimen

 

Intravenously drip (in the form of a dropper) (40-80 drops per minute), through the device with a filter and a polymer needle to connect to the container.

 

The dose depends on the age of the patient and the severity of intoxication.

 

Single dose for adults - 200-500 ml; for children - 5-10 ml per kilogram; the maximum single dose for infants is 50-70 ml, 2-5 years - 100 ml, 5-10 years -150 ml, 10-15 years - 200 ml. The drug is administered once or up to 2 times a day for 1-10 days, depending on the severity of intoxication.

 

In acute gastrointestinal infections, burn and radiation diseases are administered 1-2 times a day; with hemolytic disease and toxemia of newborns - 2-8 times a day (daily or every other day); with large focal myocardial infarction (on the first day) - 200 ml once, with complications on the second day - 200 ml.

 

Side effect

  • lowering blood pressure;
  • tachycardia (increased heart rate);
  • difficulty breathing (with rapid administration);
  • allergic reactions of varying severity (up to the development of anaphylactic shock);
  • infection at the injection site;
  • thrombosis (blockage of blood vessels) or phlebitis (inflammation of the vein wall), spreading from the site of infusion.

 

Contraindications

  • intracranial hypertension;
  • hemorrhagic stroke;
  • condition after traumatic brain injury;
  • chronic heart failure 2b-3 degrees;
  • respiratory insufficiency;
  • severe allergic reactions;
  • thromboembolism;
  • oliguria, anuria, acute nephritis;
  • bronchial asthma;
  • phlebothrombosis;
  • hypersensitivity.

 

Application in pregnancy and lactation

 

Hemodesis is allowed to be used to treat pregnant women according to the dosing regimen.

 

Use in children

 

The application is possible according to the dosing regimen.

 

special instructions

 

With extensive burns combined with the introduction of plasma, albumin, gamma globulin.

 

Before the start of the infusion, it is necessary to check the expiry date of the package. The drug should be clear, free of sediment, sediment and mold. Pressing the container with the preparation is checked for its tightness and the integrity of the package.The results of visual inspection are recorded in the medical history. During the treatment, it is necessary to monitor blood pressure and the patient's condition.

 

Before administration, the solution is warmed to body temperature.

 

Drug Interactions

 

When the solution of Hemodesis is used together with drugs, it is possible to reduce their therapeutic effect, due to the formation of complex compounds with polyvinylpyrrolidone.

 

Analogues of the drug Hemodez

 

The hemoglobin has no structural analogs in terms of the composition of the active substances.

 

Analogues on the pharmacological group (regulators of water-electrolyte balance and KHS in combinations):

  • Acesol;
  • Volulayt;
  • Hemodez H;
  • Hemodez 8000;
  • Disol;
  • Ionoplasm;
  • Infukol;
  • Yonosterol;
  • Quintasol;
  • Custodiol;
  • Mafusol;
  • Sodium fumarate is complex;
  • Neohemodeisis;
  • Normakor;
  • Plasma-Lit 148;
  • Perftoran;
  • Polyoxidin;
  • Polyoxyfumarin;
  • Ringer's solution;
  • Hartmann's solution;
  • Regidron;
  • Reogluman;
  • Reomacrodex;
  • Reopoliglyukin;
  • Ringer;
  • Sorbilact;
  • Seprotin;
  • Trihydrosol;
  • Trisol;
  • Chlosol.

 

Response of a toxicologist

 

Hemodez is an effective detoxification drug.Its composition includes povidone (polyvinylpyrrolidone), which can quickly bind the circulating toxins in the blood and remove them from the body. When it is used, the condition of patients suffering from severe intoxications, developing due to toxic pathologies of the digestive tract, dyspepsia, salmonellosis, dysentery, improves significantly. The use of Hemodesis greatly facilitates the condition of patients with sepsis, intestinal obstruction, thyrotoxicosis. I often prescribe infusions of Hemodesis to pregnant women suffering from late toxicosis.

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