Dicetel - instructions for use, reviews, analogs and forms of release (tablets of 50 mg and 100 mg) drugs for the treatment of irritable bowel syndrome and dyskinesia in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Dicetel. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Dicetel in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Dicetel in the presence of existing structural analogues. Use for the treatment of irritable bowel syndrome and dyskinesia of the gallbladder and ducts in adults, children, as well as during pregnancy and lactation. Composition of the preparation.

Dicetel - spasmolytic drug with a selective effect on the gastrointestinal tract (GIT). Inhibits the flow of calcium into the cells of the smooth muscles of the intestine. Studies in animals have shown that pinaverium bromide reduces the effects of stimulation of sensitive neurons. Does not possess anticholinergic action. Has no effect on the cardiovascular system.

Composition

Pinaverium bromide + excipients.

Pharmacokinetics

After oral administration, the Dicetel is rapidly absorbed and reaches Cmax in the plasma after 1 h. Pinaverium bromide has a high ability to bind to plasma proteins (95-96%). It is actively metabolized in the liver. Absolute bioavailability is very low (less than 1%). It is excreted mainly from the body with feces.

Indications

• symptomatic treatment of pain, transit disorders of intestinal contents and discomfort associated with functional bowel movement (irritable bowel syndrome);
• symptomatic treatment of pain associated with functional disorders of the biliary tract (dyskinesia of the gallbladder and bile ducts);
• Preparation for the roentgenological examination of the gastrointestinal tract with the use of barium sulfate.

Forms of release

Tablets coated with 50 mg and 100 mg.

Instructions for use and dosing regimen

The drug is intended for oral administration.

Tablets are taken with food wholly, without chewing or dissolving, with a glass of water to prevent the contact of pinaverium bromide with the mucosa of the esophagus.

Tablets, film-coated, 50 mg prescribed in a daily dose of 1 tablet 3 times a day or 2 tablets 2 times a day. If necessary, the daily dose can be increased to 2 tablets 3 times a day. When preparing for the X-ray examination of the digestive tract - 2 tablets 2 times a day for 3 days before the test.

Tablets, film-coated, 100 mg prescribed in a daily dose of 1 tablet 2 times a day. If necessary, the daily dose can be increased to 1 tablet 3 times a day. When preparing for X-ray examination - 1 tablet 2 times a day for 3 days before the test.

Side effect

• pain in the abdomen;
• diarrhea;
• nausea, vomiting;
• dysphagia;
• damage to the mucosa of the esophagus;
• rash;
• itching;
• hives;
• erythema;
• hypersensitivity to the components of the drug.

Contraindications

• deficiency of lactase, galactose intolerance, glucose-galactose malabsorption;
• children and adolescents under the age of 18;
• hypersensitivity to any of the components of the drug.

Application in pregnancy and lactation

There is insufficient data on the use of Dicetel in pregnant women. The potential risk to humans is unknown. The use of the drug during pregnancy is allowed if the benefit from the use for the mother exceeds the potential risk to the fetus.

In addition, it should be taken into account that the composition of the drug includes bromine. In this regard, the appointment of pinaverium bromide at the end of pregnancy can cause neurological disorders (lowering blood pressure, sedation) in a newborn.

There is insufficient information on the induction of pinaverium bromide with breast milk. Physico-chemical and accessible data on the pharmacodynamics and toxicology of the drug Dicetel indicate the excretion of the drug with the mother's milk, and therefore the risk for the infant can not be ruled out. Dicetel should not be used during lactation.

Use in children

Due to the lack of data on efficacy and safety, the use of the drug in children and adolescents under the age of 18 is not recommended.

special instructions

In connection with the risk of damage to the mucous membrane of the esophagus, you must carefully follow the recommendations for use. Patients with esophagitis and / or hernia of the esophagus should pay special attention to the correct use of the drug.

Impact on the ability to drive vehicles and manage mechanisms

Studies on the effect of the drug on the ability to drive and other mechanisms were not carried out.

Drug Interactions

Clinical studies have not revealed any interactions of Dicetel with cardiac glycosides, oral hypoglycemic agents, insulin, oral anticoagulants and heparin.

Simultaneous administration of anticholinergics can increase the cramping of spasms.

No effect of the drug on the results of laboratory tests for determining the concentration of drugs was noted.

Analogues of the drug Dicetel

Structural analogues of the active ingredient do not have the drug Dicetel. The drug is unique in terms of the active ingredient in the composition.

Analogues on the curative effect (remedies for the treatment of irritable bowel syndrome):

• Bactistatin;
• Betamax;
• Galidor;
• Duspatalin;
• Irmalax;
• Colorado;
• Lactofiltrum;
• Meteopazmil;
• Mukofalk;
• Neointestopan;
• But the spine;
• But the forte;
• Novo Passit;
• Papaverine;
• Spasmonet;
• Spasmonet forte;
• Spacock;
• Sparex;
• Trimedate;
• Eglek;
• Enterosan.

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