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Trimedat - instructions for use, reviews, analogs and formulations (tablets of 100 mg and 200 mg) of the drug for the treatment of nausea, vomiting and other dyspeptic disorders in adults, children and pregnancy. Frequency of admission (before or after eating)

Trimedat - instructions for use, reviews, analogs and formulations (tablets of 100 mg and 200 mg) of the drug for the treatment of nausea, vomiting and other dyspeptic disorders in adults, children and pregnancy. Frequency of admission (before or after eating)

In this article, you can read the instructions for using the drug Trimedate. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Trimedata in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Trimedate in the presence of existing structural analogs.Use for the treatment of nausea, vomiting and other dyspeptic disorders in spasms and irritable bowel syndrome (IBS) in adults, children, as well as in pregnancy and lactation. The frequency of taking the drug (before or after eating).

 

Trimedate - regulator of gastrointestinal motility. Trimebutin (the active ingredient of the preparation Trimedat), acting on the enkephalinergic system of the intestine, is the regulator of its peristalsis. Possessing affinity for the receptors of excitation and suppression, it has a stimulating effect in hypokinetic states of smooth muscles of the intestine and spasmolytic - in hyperkinetic.

 

The drug acts throughout the gastrointestinal tract, reduces the pressure of the sphincter of the esophagus, promotes the emptying of the stomach and enhances the intestinal peristalsis, and also promotes the response of the smooth muscles of the colon to food stimuli.

 

Trimedate restores the normal physiological activity of the musculature of the intestine for various gastrointestinal disorders associated with motor disorders.

 

Composition

 

Trimebutina maleate + excipients.

 

Pharmacokinetics

 

After ingestion, Trimedate is rapidly absorbed from the digestive tract. Bioavailability is 4-6%. The degree of binding to plasma proteins is low - about 5%. Trimebutin penetrates insignificantly through the placental barrier. Biotransformatsya in the liver. Trimebutin is excreted in urine mainly in the form of metabolites (approximately 70% during the first 24 hours).

 

Indications

 

Disorders of GI motility in the following functional diseases and conditions:

  • gastroesophageal reflux disease;
  • dyspeptic disorders in gastroduodenal diseases (abdominal pain, digestive disorders, nausea, vomiting);
  • irritable bowel syndrome (IBS), manifested by pain, colic in the abdominal cavity, intestinal spasms, flatulence, diarrhea and / or constipation;
  • postoperative paralytic intestinal obstruction;
  • preparation for X-ray / endoscopic examination of the digestive tract;
  • Dyspeptic disorders in children associated with a violation of GI motility.

 

Forms of release

 

Tablets of 100 mg and 200 mg.

 

Instructions for use and dosage

 

Adults and children over 12 years of age the drug is administered orally 100-200 mg 3 times a day for 15 minutes before meals.To prevent the recurrence of irritable bowel syndrome after the course of treatment during remission, it is recommended to continue taking the drug at a dose of 300 mg per day for 12 weeks.

 

Children aged 5-12 years are prescribed 50 mg 3 times a day, children aged 3-5 years - 25 mg 3 times a day.

 

Side effect

  • skin reactions.

 

Contraindications

  • children under 3 years (for tablets);
  • hypersensitivity to the components of the drug.

 

Application in pregnancy and lactation

 

It is not recommended to use Trimedate in the first trimester of pregnancy.

 

Not recommended application Trimedat during lactation (breast-feeding) due to lack of reliable clinical data supporting the safety of the drug.

 

In experimental studies, there was no evidence of teratogenicity and embryotoxicity of the drug.

 

Use in children

 

The drug in the form of tablets is not prescribed for children under the age of 3 years

 

special instructions

 

The course of treatment of irritable bowel syndrome in the acute period of 600 mg a day for 4 weeks and continued after the course of treatment in a dose of 300mg a day for 12 weeks, to avoid recurrence.

 

Drug Interactions

 

Drug interaction of the drug Trimedate is not described.

 

Analogues of the drug Trimedat

 

Structural analogs for the active substance:

  • Trimebutin maleate.

 

Analogues on the medicinal effect (remedies for the treatment of irritable bowel syndrome):

  • Bactistatin;
  • Betamax;
  • Galidor;
  • Duspatalin;
  • Irmalax (dietary fiber with vitamin C and citrus flavor);
  • Meteopazmil;
  • Mukofalk;
  • Neointestopan;
  • But the spine;
  • But the forte;
  • Novo Passit;
  • Papaverine;
  • Platyphylline;
  • Spasmonet;
  • Spasmonet forte;
  • Spacock;
  • Eglek;
  • Enterosan.

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Reviews (42):
Guests
Christie
A good drug, I like it, it stimulates the intestinal peristalsis. I was appointed recently and I gradually recovered.Now I live an active life and almost forgot about constant constipation.
Guests
Laura
I had problems with the stomach and intestines when there was a stressful situation. Against this background, bloating, colic, severe spasms, constipation, or diarrhea. I went to the doctors and finally appointed a trimedate. I did not help immediately, took about a month and only then I felt relieved.
Guests
olga
I take trimedate, according to the appointment of a gastroenterologist. Has helped. I accept 10 days, but it takes another 20 days, but somehow it's expensive for a pensioner. Is there an analogue of this drug, which is cheaper?
Administrators
admin
olgaThere are no direct analogs of the preparation of Trimedate for active substance in Russia. The direct analogue of the given medicine of Trimebutin maleate specified in the instructions is not supplied to Russia. If the financial condition does not allow the purchase of expensive Trimedate, then it is possible to agree with the doctor on the replacement of other drugs, with a similar mechanism of action, but with another active substance.
Guests
galena
Very good drug. Helps better no-shpy. It improves the normal functioning of the intestine. I have IBS. And not so expensive.
Guests
Galina
Just started taking, but there are shifts ...
Guests
love
The drug is good. I like this.
Guests
Voronkova N.I.
And if you stop taking the drug after a 4-week treatment for a crack in the anus and constipation, there will be a withdrawal syndrome?
Administrators
admin
Voronkova N.I., Withdrawal syndrome with the use of the drug Trimedat was not noted. So you can safely cancel the drug after the end of the prescribed course of treatment, no consequences should not be.
Guests
Alesya Kovtun
Before pregnancy, he applied, when there was swelling and heaviness, tried others, but in Trimedata the effect is better and comes faster. After pregnancy I fed for a long time, I was afraid even to drink coffee, not like tablets ... And somehow I forgot about them.And then my girlfriend took her stomach right in the gym ... She drank a pill, I looked at the package familiar, said from pain and colic helps. Now I bought it and put it in the medicine chest too, in reserve.
Guests
Alla
An excellent drug, but you must remember that the course of treatment 4 weeks, with a one-time admission can not immediately hope for results. 3 times a day (preferably with an interval of 8 hours was to evenly) 4 weeks.
Administrators
admin
Alla and the rest, I bring you a warning for active advertising of the drug Trimedat in the Directory under the guise of reviews of ordinary visitors. I have been watching your attempts for a long time, and most of these reviews have been deleted, but you all are in need, so for the time being a warning, but if such an advertising policy continues, a more severe punishment will follow - all those who noted such reviews and the moderation policy for this drug will be significantly toughened . Let's live in peace and no more hooliganism!
Guests
Lyudmila
The drug was prescribed by a neurologist for the treatment of irritable bowel syndrome 2 times a day for 200 mg. I drank almost a pack of pills. Almost immediately there was a strange stool from hard to diarrhea. The pain in the umbilical region on the left has increased, it is poorly cropped. Nausea increased, appetite disappeared. I was surprised that I found only one site where people gave positive reviews and negative ones, and several people had my problems. From the positive, I note that meteorism disappeared. In general, I can not yet give this drug a positive characteristic. If all of the above does not work, I will stop taking it.
Guests
Lena
I like. Calms and a headache.
Visitors
Elenalena
The gastroenterologist has appointed or nominated trimedat. Has spent on drink a course of 4 weeks. It seems that the chair has improved, and the pain has passed. But after stopping the drug, a month later, the problem recalled itself again. Can I start taking this medication again or do I need another treatment?
Administrators
admin
Elenalena, Trimedat take a minimum of 3-month courses. During the month, a specialist can only assess the adequacy of the appointment (that is, began to help the drug or not). In your case, you need to continue treatment, because there is a positive dynamics. Perhaps the doctor recommended that you show yourself a month after the start of treatment for the necessary adjustments.
Guests
Aleftina
Prompt, it is possible to replace Trimedat with Drotaverinom? Thank you.
Administrators
admin
AleftinaIf you use Trimedate to treat GERD or irritable bowel syndrome, it is unlikely that such substitution is appropriate. Plus Drotaverin and Trimedat are not analogues to the active substance, although they are related to spasmodics, but they have different points of application. This issue requires discussion with your doctor, as he knows your pathology and will be able to recommend an adequate substitute.
Visitors
evgen
Tortured! I take a bunch of drugs, laxatives, but they do not last long.And do not recommend taking them often - the body gets used to them. One doctor advised to take Trimedat. I would like to know how he acts. Do you get used to it, because you are advised to take it for a long time?
Administrators
admin
evgenThe effect of the drug Trimedate is described in the instructions. Regarding constipation, if the diet is adjusted (a sufficient amount of rough, intractable fiber is present in the diet), plus sufficient water regime (drinking with constipation is necessary a lot and often), there is no dysbiosis and other abnormalities in the intestinal microflora (stool analysis), also a diagnosis of thick (colonoscopy) and no abnormalities are found, then it is possible to put a violation of GI motility with symptoms in the form of constipation and appoint Trimedat.
Visitors
evgen
Thanks for the advice! I realized if your intestines are healthy, then you can take Trimedat. Well, if the intestines are not all right, you can not take it anymore. This "medicine" only for healthy people with healthy wallets!
Administrators
admin
evgen, We will assume that you understand my recommendation. Who needs it - that Trimedat will help.
Guests
Svetlana Weinblat
That I just did not drink, I mean from the stomach, now I must try to trimmedate, although I doubt that it will help. Some kind of moving in the stomach.
Guests
NatNik
Gallbladder removed a long time ago. Pain in the right side began to appear periodically with nausea, eructation. The abdominal ultrasound, FGS of the stomach, colonoscopy and the therapist assumed that it was an inflammation of the small intestine and prescribed trimedate. Improvement was felt only after two weeks, the pain was gone. A month drank, but then caught the flu and, accordingly, had to be treated for it. Again the pain in the right side returned and the feces became green.
Visitors
tysia
After the operation in the hospital, they were treated with antibiotics, they discharged home, the stomach began to ache. A week later I drank alone for 5 days, bifiform 15 days, now switched to probiogol.Drawing pains in the abdomen do not pass. Today the doctor prescribed trimedate 100 mg 3 r. per day for a month. Is it possible to drink trimedate with probiobol or just one trimedate?
Administrators
admin
tysiaYou can take Trimedat with ProbiLog. According to the instruction of negative side effects with such a joint admission should not be. Given the previous treatment with probiotics and their inefficiency (as I understood from the question), the advisability of taking this group of drugs in the future is questionable and it is better to focus on taking only Trimedat, as the doctor advised.
Visitors
tysia
Thank you for your prompt response. Pleasantly surprised. Now I will often contact you for advice. Happy New Year!
Guests
Mind
Did not like the drug trimedate - headache, pressure jumps, could not understand from what, in the annotation, in the side there is an allergic reaction and everything, but in fact, pobachek plenty and heart palpitations.I regretted that I had bought - thrown away money, and constipation from it.
Guests
Ioannina
I read all the reviews and I realized that it's expensive, there are no analogues, but it will help or torture me with little details. The doctor has written out. The stomach hurts, I do not know what to eat, it's terrible because of pains and constipation.
Guests
Love
My constipation only increased.
Guests
raile
After taking the drug immediately increased pressure, tachycardia appeared.
Guests
Tatyana
After a stressful situation, unpleasant sensations began in the left side of the abdomen, a swelling. She started to drink Trimedat. Surprisingly, almost immediately everything went away, but since after removing the gall, with a chair I had problems, I decided to fix the result and drink this drug course. I felt great, but when the first pack was finished, our analogue, Neboutin, was advised in the pharmacy. It is cheaper by a hundred rubles, and the main substance is the same. After the first pill, drunk in the middle of the day, everything was normal, but closer to the night, after the second, there was a pain in the stomach and in the upper abdomen.And now I woke up before the alarm clock, but with the condition that was before the reception of Trimedat. I do not know what to think. If the Neutrut is an absolute analog, then why is there no action? It is not excluded the option, of course, that the last tablet I took it is not quite right, just drank at night and did not eat anything. I'll try, of course, to observe the process of the day, observing the rules. Or is there any difference in these preparations and could not be substituted for one another in the course of treatment?
Administrators
admin
TatyanaThe active ingredient in the preparations Trimedat and Neobutin is the same - trimebutine maleate and is produced in Korea for one and the other drug, though at different plants. Sometimes it happens that absolute analogs can have different effects and have different side effects. I always try to assign to my patients those trademarks that show effectiveness and, in extreme cases, translate them into analogues (most often because of financial problems and high cost of original drugs). What caused the instability of health status when taking the analogue of Trimedate will be difficult to determine,but I would return to that medicine, which proved its positive effect in your case.
Visitors
Anjik
Good afternoon. The gastroenterologist has written out Trimedatum, but I have forgotten to inform him about calculous cholecystitis. Can I take it, is not it choleretic?
Administrators
admin
Anjik, The ban on the use of the drug Trimedat with calculous cholecystitis is not, as there is no mention of a negative effect on the course of cholelithiasis as a whole.
Guests
Tatyana
It turns out that Trimedat reduces the pressure of the esophageal sphincter, there is an eructation and heartburn.
Guests
Thani
Tell me, is there an addiction to Trimedat?
Administrators
admin
ThaniOfficially, no. But some patients take Trimedat for a long time and after the withdrawal of the drugs there appears an unreasonable (and sometimes justified) fear of the return of symptoms. Call it addictive, but you can not pass by.
Guests
Oksana Dohlenko
Could you tell me whether it makes sense to take trimedate together with eubicor?
Administrators
admin
Oksana Dohlenko, It depends that we treat. You can take Eubicor and Trimedat together.
Visitors
markizneangelov
Good evening. Tell me, please, whether it is possible to take trimedate, if the expiration date has already expired as a year and a half?
Administrators
admin
markizneangelov, It is impossible. After such delay, the medicine could change its chemical properties and no one will be able to predict the possible outcome of such treatment.

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