Tsereton - instructions for use, analogs, testimonials and release forms (capsules or tablets 400 mg, injections in injections) for the treatment of the consequences of stroke and head injuries in adults, children and pregnancy. Composition

In this article, you can read the instructions for using the drug Cereton. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Cereton in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Tsereton in the presence of existing structural analogs.Use to treat vascular dementia, the consequences of stroke and head injuries in adults, children, as well as during pregnancy and lactation. Composition of a nootropic preparation.

Cereton - Nootropic preparation. Cholinomimetic of central action, which contains 40.5% of metabolically protected choline.

Metabolic protection contributes to the release of choline in the brain. Provides the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes, improves blood flow and enhances metabolic processes in the central nervous system, activates the reticular formation. Increases the linear velocity of blood flow on the side of traumatic brain injury, contributes to the normalization of spatiotemporal characteristics of spontaneous bioelectric activity of the brain, regression of focal neurological symptoms and restoration of consciousness. Has a positive effect on cognitive and behavioral reactions of patients with cerebral vascular diseases (discirculatory encephalopathy and residual phenomena of cerebral circulation disorders).

Provides a preventive and corrective effect on the pathogenetic factors of the involutionary psychoorganic syndrome,changes the phospholipid composition of neuronal membranes and reduces cholinergic activity. Stimulates a dose-dependent release of acetylcholine under physiological conditions. Participating in the synthesis of phosphatidylcholine (membrane phospholipid), improves synaptic transmission, plasticity of neuronal membranes, receptor function.

Has no effect on the reproductive cycle and does not have a teratogenic, mutagenic effect.

Composition

Choline alphoscerate + excipients.

Pharmacokinetics

Absorption - 88%. Easily penetrates the blood-brain barrier (BBB). When administered orally, the concentration in the brain is 45% of that in the plasma. It accumulates mainly in the brain, lungs and liver. 85% of the drug is excreted in the form of carbon dioxide, the rest (15%) is excreted by the kidneys and through the intestine.

Indications

• the recovery period of severe craniocerebral trauma and ischemic stroke, the recovery period of hemorrhagic stroke, with focal hemispheric symptoms or symptoms of brainstem lesions;
• psychoorganic syndrome in the background of degenerative and involuntary changes in the brain;
• cognitive disorders (impaired mental function, memory, confusion, disorientation, decreased motivation, initiative and ability to concentrate), incl. with dementia and encephalopathy;
• senile pseudomelanchia.

Forms of release

Capsules 400 mg (sometimes mistakenly called pills).

Solution for intravenous and intramuscular injection (injections in ampoules for injection).

Instructions for use and dosing regimen

Capsules

In the recovery period of craniocerebral trauma, ischemic or hemorrhagic stroke, Tsereton is prescribed 800 mg in the morning and 400 mg in the daytime for 6 months.

With chronic cerebrovascular insufficiency and dementia syndromes, Cereton is prescribed 400 mg 3 times daily, preferably after meals, for 3-6 months.

Ampoules

When acute conditions are administered intravenously (slowly) or deeply intramuscularly (slowly) 1 g (1 ampoule) per day for 10-15 days.

Side effect

• nausea (mainly due to dopaminergic activation);
• constipation, diarrhea;
• dryness of the oral mucosa;
• pharyngitis;
• headache;
• drowsiness;
• insomnia;
• aggressiveness;
• anxiety;
• nervousness;
• cerebral ischemia;
• convulsions;
• dizziness;
• rash;
• hives;
• pain in the injection site;
• increased frequency of urination;
• allergic reactions.

Contraindications

• acute stage of hemorrhagic stroke;
• pregnancy;
• the period of breastfeeding;
• children under 18 years of age (due to lack of data);
• hypersensitivity to the drug.

Application in pregnancy and lactation

The drug is contraindicated in pregnancy and lactation (breastfeeding).

Use in children

Contraindicated in children and adolescents under 18 years.

Application in elderly patients

The application is possible according to the dosing regimen.

special instructions

The drug is released by prescription.

Impact on the ability to drive vehicles and manage mechanisms

Tsereton does not affect the speed of psychomotor reactions.

Drug Interactions

Clinically significant drug interaction Tsereton with other drugs has not been identified.

Analogues of the drug Tsereton

Structural analogs for the active substance:

• Glaser;
• Gliatilin;
• Glycerylphosphorylcholine hydrate;
• Delecite;
• Noochlin Rompharm;
• Phosal GFH;
• Choline alphoscerate;
• Choline alfoscerate hydrate;
• Holilitil;
• Cerepro.

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