Normax - instructions for use, reviews, analogs and forms of release (eye drops and ear 0.3%, tablets 400 mg) of the antibiotic drug for the treatment of otitis, cystitis and adnexitis in adults, children and pregnancy

In this article, you can read the instructions for using the drug Normax. There are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors of specialists on the use of antibiotic Normax in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Normax in the presence of existing structural analogs. Use for the treatment of otitis, cystitis and adnexitis in adults, children, as well as during pregnancy and lactation.

Normax - an antibacterial drug from the group of fluoroquinolones.Has a wide range of bactericidal effects.

Highly active against Gram-negative bacteria: Escherichia coli (E. coli), Haemophilus influenzae, Haemophilus ducreyi, Klebsiella spp. (incl. Klebsiella pneumoniae (Klebsiella)), Morganella morganii, Neisseria spp. (incl. Neisseria gonorrhoeae), Salmonella spp. (salmonella), Shigella spp. (shigella), Proteus spp., Pseudomonas aeruginosa, Enterobacter spp., Chlamydia trachomatis (chlamydia), Citrobacter freundii, Serratia spp., Yersinia spp.

It is active against gram-positive bacteria: Staphylococcus aureus (including strains producing penicillinase and methicillin-resistant strains), Staphylococcus epidermidis (Staphylococcus aureus), Staphylococcus saprophyticus, some strains of Streptococcus spp.

The drug is not very sensitive to Enterococcus spp. (enterococcus) and Acinetobacter spp.

Anaerobic bacteria are resistant to Normax.

Composition

Norfloxacin + excipients.

Pharmacokinetics

When ingested absorbed 30-40% of the dose, eating reduces the absorption rate. Norfloxacin is well distributed in the tissues of the genitourinary system. About 30% of the active substance is excreted unchanged in the urine.

With topical application of the drug, the therapeutic concentration of the active substance is achieved in the tissues and biological fluids of the eye or in the ear tissues.

Indications

For oral administration

Treatment of infectious-inflammatory diseases caused by microorganisms sensitive to the preparation:

• diseases of the urinary tract;
• infections of the pelvic organs (including adnexitis, prostatitis);
• intestinal infections;
• infections of the skin and soft tissues;
• infections of the paranasal sinuses, pharynx, larynx, middle ear;
• ophthalmic infections.

For topical application

Treatment of infectious-inflammatory diseases caused by microorganisms sensitive to the preparation:

• conjunctivitis (including gonococcal);
• keratitis;
• keratoconjunctivitis;
• corneal ulcer;
• blepharitis;
• blepharoconjunctivitis;
• trachoma;
• otitis externa;
• acute and chronic otitis media;
• otitis media;
• infectious eustachyte.

Prevention of eye infections after removal of a foreign body from the cornea or conjunctiva, after damage by chemical or physical means, before and after surgical interventions.

Prevention of infectious otitis before and after surgery, with ear trauma, removal of foreign body from the external auditory canal, accompanied by damage to the ear tissues.

Forms of release

Eye and ear drops 0,3%.

The tablets covered with a cover of 400 mg.

Instructions for use and how to use them

Drops

Assign 1-2 drops to the affected eye or ear 4 times a day.If necessary, on the first day of application, the dose may be increased to 1-2 drops every 2 hours. After the disappearance of the symptoms of the disease, the drug should be continued for a further 48 hours.

In acute and chronic trachoma, 2 drops are prescribed in each eye 2-4 times a day for 1-2 months.

Before instillation in the ear drops Normax should be sanitized external auditory meatus. Drops should have body temperature. The patient should lie sideways or tilt his head to facilitate instillation. After digging in, you need to drop into the ear canal, pulling the earlobe down and back. Keep the head in the indicated position for approximately 2 minutes. You can put in the outer ear canal wool turunda.

Pills

Inside take 400 mg 2 times a day. In severe infections, a single dose can be increased to 800 mg. The duration of treatment is determined individually. The minimum course of treatment is 3 days.

Side effect

• nausea;
• heartburn;
• anorexia;
• diarrhea;
• stomach ache;
• headache;
• dizziness;
• feeling tired;
• sleep disorders;
• irritability;
• sense of anxiety;
• interstitial nephritis;
• skin rash;
• itching;
• angioedema.

Contraindications

• children and adolescence up to 15 years;
• pregnancy;
• lactation (breastfeeding);
• increased sensitivity to norfloxacin and other fluoroquinolone drugs.

Application in pregnancy and lactation

The drug Normax is not recommended for use during pregnancy and lactation (breastfeeding).

Use in children

The drug is contraindicated in children and adolescents under 15 years.

special instructions

Normaks in the form of tablets should be used with caution in patients with epilepsy, convulsive syndrome of another etiology, marked violations of the liver and / or kidney function.

The drug should be taken at least 2 hours before or 2 hours after taking antacids or preparations containing iron, magnesium, zinc or sucralfate.

Normax in the form of drops is for local use only.

To achieve a better therapeutic effect, drops should be used in combination with systemic antimicrobial therapy (except for mild cases).

It is necessary to protect the solution and dropper from contamination.

Impact on the ability to drive vehicles and manage mechanisms

Within 30 minutes after instillation of the drug in the eye should refrain from engaging in potentially hazardous activities that require increased attention.

Drug Interactions

With the simultaneous administration of Normax and warfarin, the anticoagulant effect of the latter is enhanced.

With the simultaneous administration of Normax and cyclosporine, there is an increase in the concentration of the latter in the blood plasma.

With the simultaneous administration of Normax with antacids or preparations containing iron, magnesium, calcium, zinc, sucralfate, the absorption of norfloxacin is reduced by the formation of complexons with metal ions.

Pharmaceutical interaction

A solution of norfloxacin is incompatible with drugs having pH 3-4 that are physically or chemically unstable.

Analogues of the drug Normax

Structural analogs for the active substance:

• Loxon 400;
• Nolycin;
• Norbaktin;
• Norillet;
• Noroksin;
• Norfacin;
• Norfloxacin;
• Renor;
• Sofazine;
• Chibroxin;
• Utibid.

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