Stoppier - instructions for use, analogs, reviews and release forms (suspension or syrup 220 mg, tablets 100 mg) drugs for the treatment of diarrhea or diarrhea in adults, children (including infants) and during pregnancy. Composition and alcohol
In this article, you can read the instructions for using the drug Stoppier. Presented are reviews of visitors to the site - consumers of this medication, as well as opinions of doctors specialists on the use of Stopdiar in their practice. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Stopdiar in the presence of existing structural analogues. Use to treat diarrhea or diarrhea of infectious origin in adults, children (including infants),as well as during pregnancy and lactation. Composition and interaction of the drug with alcohol.
Stoppier - antidiarrhoeal preparation. Nifuroxazide (active ingredient of Stoppediar) is a derivative of nitrofuran, it has antibacterial action against gastrointestinal gram-positive bacteria (Staphylococcus spp., Streptococcus spp.) And some gram-negative bacteria (Salmonella spp. (Salmonella), Shigella spp (shigella), Klebsiella spp. (Klebsiella), Escherichia coli (E. coli)). Does not affect the composition of normal bacterial flora of the large intestine. The detailed mechanism of action of the drug is unknown.
The stoppier presumably inhibits the activity of dehydrogenases and the synthesis of proteins in bacterial cells. Does not cause the emergence of drug-resistant strains, nor did cross-resistance to other antibacterial drugs.
The effectiveness of nifuroxazide does not depend on the pH existing in the lumen of the intestine, nor on the sensitivity of microorganisms to antibacterial drugs. The drug is practically not absorbed from the digestive tract, it acts exclusively in the lumen of the intestine.
In therapeutic doses, it practically does not disturb the balance of the symbiotic bacterial flora of the intestine; does not cause the development of resistant strains of pathogenic microorganisms and the cross-resistance of bacteria to other antimicrobial agents, which allows, if necessary, in generalized infections to prescribe it in a complex therapy with systemic drugs. When intestinal infections of viral origin prevents the development of bacterial superinfection.
Composition
Nifuroxazide + excipients.
Pharmacokinetics
Nifuroxazide is slightly soluble. After oral administration, it is practically not absorbed from the digestive tract and does not have a systemic effect. It is excreted through the intestine.
Indications
- acute and chronic diarrhea caused by intestinal Gram-positive bacteria (Staphylococcus spp., Streptococcus spp.), as well as some gram-negative bacteria (Haemophilus influenzae, Salmonella spp., Shigella spp., Klebsiella spp., Escherichia coli, Proteus spp., Enterobacter spp. ).
Forms of release
Tablets coated with 100 mg.
Suspension for ingestion 220 mg (sometimes mistakenly called syrup).
Instructions for use and dosing regimen
Suspension
The drug is used inside. Before use, the vial should be shaken thoroughly until a uniform suspension is obtained. Dosage and frequency of use:
- age from 2 months to 6 months of 1-2 measures. spoons for 2.5 ml 2 times a day;
- age from 6 months to 6 years, 1 measure. spoon for 5 ml 3 times a day;
- age from 6 years to 18 years of age. spoon for 5 ml 4 times a day;
- adults with 1 measurement. spoon for 5 ml 4 times a day.
1 measuring spoon for 2.5 ml contains 110 mg of nifuroxazide. 1 measuring spoon for 5 ml contains 220 mg of nifuroxazide.
The drug is recommended to be taken at regular intervals, regardless of food intake. The course of treatment is 5-7 days.
Pills
Adults and children over 6 years of age are prescribed 2 tablets (200 mg) 4 times a day after 6 hours. The course of treatment is 6 days. Before use, consult a physician.
Side effect
- abdominal pain;
- dyspnea;
- skin rashes;
- itching;
- nausea;
- increased diarrhea (these symptoms do not require special treatment and discontinuation of the drug).
Contraindications
- children under 6 years (for tablets), up to 2 months (for suspension);
- hypersensitivity reactions to derivatives of 5-nitrofuran.
Application in pregnancy and lactation
Caution should be used during pregnancy and lactation.
Use in children
Tablets are a contraindicated for children under the age of 6 years.Suspension is contraindicated for children under 2 months (newborns). The use of a suspension in infants from 2 months of age is allowed.
special instructions
During treatment, it is necessary orally or parenterally (depending on the patient's condition) to compensate for fluid loss.
During the treatment should adhere to a certain diet: do not eat raw fruits and vegetables, juices, spicy and fatty dishes.
Before the suspension is prescribed to infants, it is necessary to exclude from them an inborn deficiency of enzymes that break down sucrose.
The use of alcoholic beverages during treatment Stopdiar can cause a disulfiram-like reaction.
Impact on the ability to drive vehicles and manage mechanisms
The drug does not affect the ability to drive and work with other mechanisms.
Drug Interactions
Because nifuroxazide is not absorbed from the digestive tract, the possibility of interaction with other drugs is unlikely.
Analogues of the drug Stopdiar
Structural analogs for the active substance:
- Nifuroxazide;
- Nifuroxazide Richter;
- Ecofuril;
- Enterofuryl;
- Ersefuril.
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