Detraleks - instructions for use, analogs, reviews and release form (tablets of 500 mg) of the drug for the treatment of hemorrhoids, venous disorders in adults, including during pregnancy
In this article, you can read the instructions for using the drug Detralex. Comments of visitors of the site - consumers of this medication, as well as opinions of doctors of specialists on the use of Detralex in their practice are presented. A big request is to actively add their feedback on the drug: the medicine helped or did not help get rid of the disease, which were observed complications and side effects, possibly not declared by the manufacturer in the annotation. Analogues of Detralex in the presence of existing structural analogs. Use for the treatment of hemorrhoids and venous disorders in adults, including during pregnancy and lactation.
Detralex - a drug used for violations of venous circulation. Detralex has venotonic and angioprotective properties. The drug reduces the extensibility of veins and venous congestion, reduces the permeability of capillaries and increases their resistance. The results of clinical studies confirm the pharmacological activity of the drug with respect to the indices of venous hemodynamics.
A statistically reliable dose-dependent effect was demonstrated for the following venous plethysmographic parameters: venous capacity, venous dilatability, venous emptying time.
The optimal dose-effect ratio is observed when taking 2 tablets.
Increases venous tone: with the help of venous occlusion plethysmography, a decrease in the time of venous emptying was shown. In patients with signs of severe disturbance of microcirculation, there is a (statistically significant), in comparison with placebo, an increase in capillary resistance evaluated angiostereiometrically after Detralex therapy.
Therapeutic efficacy in the treatment of functional and organic chronic venous insufficiency of the lower extremities, as well as in proctology in the treatment of hemorrhoids, is proved.
Pharmacokinetics
Diosmin (the active substance of Detralex) is excreted from the body mainly with feces. The kidneys deduce 14% of the dose.
Indications
Symptomatic therapy of venous-lymphatic insufficiency:
- feeling of heaviness in the legs;
- pain;
- "morning tiredness" of the feet;
- symptomatic therapy of acute hemorrhoids.
Forms of release
Tablets, film-coated 500 mg.
Forms of release in the form of an ointment or cream does not exist, in these cases, you can talk about a fake medicine or another type of drug.
Instructions for use and dosing regimen
The drug is prescribed inside.
The recommended dose for venous-lymphatic insufficiency is 2 tablets per day (1 tablet in the middle of the day and 1 tablet in the evening during meals).
The recommended dose for acute hemorrhoids is 6 tablets per day (3 tablets in the morning and 3 tablets in the evening) for 4 days, then 4 tablets per day (2 tablets in the morning and 2 tablets in the evening) for the next 3 days.
Side effect
- diarrhea, nausea, vomiting;
- dyspepsia;
- dizziness, headache;
- general malaise;
- rash, itching, hives.
Contraindications
- hypersensitivity to the components of the drug.
Application in pregnancy and lactation
To date, there have been no reports of any side effects in the use of the drug in pregnant women.
It is not known whether Diosmin is excreted in human breast milk, therefore it is not recommended to prescribe the drug during lactation.
In the experimental studies of teratogenic effects, Detralex was not observed.
special instructions
With exacerbation of hemorrhoids, the purpose of this drug does not replace the specific treatment of other anal disorders. The duration of treatment should not exceed the recommended time. In the event that the symptoms do not disappear after a short therapy, a proctologic examination should be performed and the therapy reviewed.
In the presence of violations of venous circulation, the maximum effect of treatment is provided by a combination with a healthy, well-balanced lifestyle, in which it is desirable to avoid long exposure to the sun, prolonged stay on the legs, and to reduce excess body weight, make walks and in some cases - wear special stockings , improving blood circulation.
Impact on the ability to drive vehicles and manage mechanisms
The drug does not affect the ability to drive vehicles and perform work that requires a high rate of psychomotor reactions.
Drug Interactions
The drug interaction Detralex is not described.
Analogues of the drug Detralex
Structural analogs for the active substance:
- Venarus;
- Purified micronized flavonoid fraction.
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